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Analyzing architectural diversity in maize plants using the skeletonimage-based method

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Journal of Integrative Agriculture 2023年第12期22卷 3804-3809页

作者： liu min-guo Thomas CAMPBELL LI Wei WANG Xi-qing College of Biological Sciences China Agricultural UniversityBeijing 100193P.R.China Frontier Technology Research Institute of China Agricultural University in Shenzhen Shenzhen 518000P.R.China Center for Crop Functional Genomics and Molecular Breeding China Agricultural UniversityBeijing 100193P.R.China Department of Biology Northeastern Illinois UniversityChicago 60625USA

Shoot architecture in maize is critical since it determines resource use,impacts wind and rain damage tolerance,and affects yield *** the diversity among inbred lines in heterosis breeding is essential,especially when describing germplasm ***,traditional geometric description methods oversimplify shoot architecture and ignore the plant’s overall architecture,making it difficult to reflect and illustrate *** study presents a new method to describe maize shoot architecture and quantifies its diversity by combining computer vision algorithms and persistent *** results reveal that persistent homology can capture key characteristics of shoot architecture in maize and other details often overlooked by traditional geometric *** on this method,the morphological diversity of shoot architecture can be mined(quantified),and the main shoot architecture types can be ***,this method can easily describe the diversity of shoot architecture in many maize materials.

关键词： maize shoot architecture persistent homology phenotyping technology morphological diversity

The Grey Relational Analysis （GRA） of Influence Factors on Exports in China

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Journal of Systems Science and Information 2006年第1期4卷 135-140页

作者： Yunfeng liu min guo Management and Economics School Beijing University of Technology Beijing 100022 China

There are many factors influencing export in China, such as the supply in domestic market, the market openness in China, the demand in overseas market, exchange rate and so on. Since the late of 1990＇s, non-tariff barriers such as antidumping, safeguard measures and technical barriers to trade （TBT） have become the main factors. We analyze the influence factors and the degree of the influence about exports in China by the Grey Relational Analysis （GRA） and put forward countermeasures for enterprises.

关键词： the grey relational analysis (GRA) TBT technology innovation

Feasibility of vertebral internal fixation using deer and sheep as animal models

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Chinese Medical Journal 2010年第17期123卷 2379-2383页

作者： liu guo-min, LI You-qiong, XU Chuan-jie, ZHU Xiao-min and liu Yi liu guo-min LI You-qiong XU Chuan-jie ZHU Xiao-min liu Yi Department of Orthopedics Second Hospital of Jilin University Changchun Jilin 130041 China Department of Pathology Second Hospital of Jilin University Changchun Jilin 130041 China Department of Gastroenterology Second Hospital of Jilin University Changchun Jilin 130041 China Basic Medical Department of Jilin University Changchun Jilin 130041 China

Backgroud Studies on new vertebral internal fixations of animals are very important prior to clinical application. This study aimed to determine the feasibility of vertebral internal fixation on morphologic and biomechanical properties using deer and sheep as animal models and comparing to human *** Thirty sets of fresh Sika deer lumbar, 30 sets of fresh sheep lumbar, and 20 sets of fresh lumbar from male cadavers were used. We examined the morphology of the centra and pedicles of the three groups, and determined the cancellous bone density and biomechanical properties in all *** There were marked differences in all parameters measured between the different species. The sizes of the upper, middle, and lower transverse diameter were largest in the human, followed by the deer, then the sheep. The index of centrum transverse diameters and sagittal diameters were less than 0.8 （a triangle）, and the deer was more similar to the human. The heights of the right vertebral pedicles and the anterior disc heights （IDH） were largest in the human, followed by the deer, then the sheep. The apparent density, elastic modulus, and ultimate load were largest in the sheep, followed by the deer, then the human. The range of motion （ROM） of functional lumbar units （FLUs） with a combined flexion-extension moment was largest in the human, followed by the deer then the sheep. Conclusions The deer lumbar is more similar to that of human in anatomical form and biomechanics than the sheep lumbar. As such, deer is more appropriate as an animal model for use in vertebral internal fixation studies.

关键词： deer sheep lumbar morphology bone density biomechanics

In vivo study of extracellular matrix coating enhancing fixation of the pedicle screw-bone＇s interface

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Chinese Medical Journal 2011年第23期124卷 3945-3952页

作者： liu guo-min ZHANG Xing-yi XU Chuan-jie ZHU Xiao-min WANG Jun liu Yi Department of Ortiaopedics Department of Thoracic Surgery Changchun Jilin 130041 China

Based on in vivo research on the effect of the coating of the extracellular matrix composition of pedicle screws on the conduction and induction of bone formation in young sheep, the aim of this study was to investigate the application of coated pedicle screws in sheep with scoliosis whose spines are under constant development. Methods Four groups of pedicle screws were randomly implanted into bilateral L2-L5 pedicles of 2.5- to 3-month-old sheep. A static experiment was performed on one side and a loading test was performed on the other side by implanting connecting rods at the L2-L3 and L4-L5 segments. The changes in the force on the coated screws and the combination of the surface of the coated screws with the surrounding bone in the growth process of young sheep＇s spines with aging were observed. After 3 months, the lumbar vertebrae with the screws were removed and examined by micro-CT, histological, and biomechanical analyses. Results Under nonloading conditions, there is bone formation around the surfaces of coated screws. The bone forming on the surface of collagen/chondroitin sulfate/hydroxyapatite coating of pedicle screws is the most, the one of the collagen / chondroitin sulfate coating and hydroxyapatite coating is followed, and no significant difference between the two groups. In terms of the trabecular bone morphology parameters of the region of interest around the surface of the pedicle screws, such as bone mineral content, bone mineral density, tissue mineral content, tissue bone mineral density, bone volume fraction, and connection density, those associated with collagen/chondroitin sulfate/hydroxyapatite coatings are largest and those unassociated with coatings are smallest. Under nonloading conditions, the pullout strength of the collagen/chondroitin sulfate/hydroxyapatite-coated screws was largest, and that of the uncoated screws was minimal （P 〈0.01）. Under loading conditions, the maximum pullout strength of each group of pedicle screws was less

关键词： hydroxyapatite collagen chondroitin sulfate micro-CT biomechanics

Inhibition of Nogo expression to promote repair after spinal cord injury

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Chinese Medical Journal 2012年第22期125卷 4044-4048页

作者： SUN Hong-hui GAO Feng liu Bin YU Hai-tao KONG Ning liu guo-min Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jinlin Peoples R China Jilin Univ Hosp 2 Dept Gen Surg Changchun 130041 Jinlin Peoples R China Jilin Univ Coll Pharm Dept Regenerat Med Changchun 130041 Jinlin Peoples R China

Background One of the reasons for poor neuroregeneration after central nervous system injury is the presence of inhibitory factors such as Nogo. Here, we tested the inhibition of Nogo by RNA interference both in vitro and in vivo, using recombinant adenovirus-mediated transfection of short hairpin RNAs, to explore a new method of treatment for spinal cord injury. Methods We designed and cloned two Nogo-specific short hairpin RNAs and an unrelated short hairpin RNA, packaged the clones into adenovirus, and amplified the recombinant virus in 293 cells. We then tested the inhibition of Nogo expression both in vitro in adenovirus-transfected oligodendrocytes and in vivo in spinal cord tissue from adenovirus-transfected spinal cord injury model rats. We tested Nogo expression at the mRNA level by reverse-transcription PCR and at the protein level by Western blotting and immunohistochemistry. Results In vitro, the two specific Nogo short hairpin RNAs decreased Nogo mRNA expression by 51% and 49%, respectively, compared with Nogo expression in cells transfected with the unrelated control small hairpin RNA （P 〈0.005）. Similarly, Nogo protein expression decreased by 50% and 48%, respectively （P 〈0.005）. In vivo, in spinal cord injury model rats, the two specific Nogo short hairpin RNAs decreased Nogo mRNA expression by 45% and 40%, respectively, compared with Nogo expression in spinal cord injury model rats transfected with the unrelated control short hairpin RNA （P 〈0.005）. The Nogo protein level was similarly decreased. Conclusions We were successful in specifically downregulating Nogo at the mRNA and protein levels by adenovirus-mediated delivery of short hairpin RNAs, both in vitro and in vivo. This confirms the effectiveness of RNA interference for the inhibition of Nogo gene expression and the efficiency of using adenovirus for delivery. Thus gene therapy may be an effective treatment for spinal cord injury.

关键词： spinal cord injury axonal regeneration RNA interference short hairpin RNA

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论董仲舒的德治思想

中国青年政治学院学报 2006年第2期25卷 57-62页

作者：刘国民中国青年政治学院中文系北京100089

在儒家德治、礼治思想的反思和现实社会政治的批判中,董仲舒阐释了其德治思想。其德治思想的突出内容有三:其一,执政者要有德,有德是内在德性和外在德行的内外合一;执政者有德不仅能成为人民的楷模,而且是实行合理政治行为的根据。其二... 详细信息

在儒家德治、礼治思想的反思和现实社会政治的批判中,董仲舒阐释了其德治思想。其德治思想的突出内容有三:其一,执政者要有德,有德是内在德性和外在德行的内外合一;执政者有德不仅能成为人民的楷模,而且是实行合理政治行为的根据。其二,执政者以仁义礼乐教化人民,唤醒和培养他们内在的仁义之质,人民自然应礼、中道,由他律的道德提升为自律的道德。其三,董仲舒为儒家的德治政治建立了天道的神圣根据,从而加强了执政者实行德治政治的责任感。

关键词：董仲舒德治思想德性教化

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徐复观对《淮南子》的解释

首都师范大学学报（社会科学版） 2008年第3期 60-66页

作者：刘国民中国青年政治学院中文系

徐复观先生在解释《淮南子》时多有创见:(1)刘安在帝室中是"二世含冤"的一系,他的"谋反"实是朝廷的诬陷;(2)刘安及其宾客是在危惧深迫的心态下同著《淮南子》,他们以浮夸瑰玮的语言,表达其烦冤悲愤之情和追求独立自由的心愿;(3)《淮南... 详细信息

徐复观先生在解释《淮南子》时多有创见:(1)刘安在帝室中是"二世含冤"的一系,他的"谋反"实是朝廷的诬陷;(2)刘安及其宾客是在危惧深迫的心态下同著《淮南子》,他们以浮夸瑰玮的语言,表达其烦冤悲愤之情和追求独立自由的心愿;(3)《淮南子》是以儒道两家思想为主的"杂家",道家并不是汉初的黄老新道家,而是老庄的原始道家,《庄子》思想尤占有突出的地位。徐先生的解释表现出两个基本的性格:一是从解释的内容来看,他突出了西汉大一统的专制政治对刘安及其宾客的压制和打击;二是在解释方法上,他把抽象的思想与活生生的时代以及具体的生命紧密结合起来。

关键词：徐复观《淮南子》解释

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评徐复观对王充哲学思想的解释

中国青年政治学院学报 2010年第2期29卷 68-73页

作者：刘国民中国青年政治学院中文系北京100089

王充的《论衡》在中国哲学史上受到太高的评价,但徐复观《王充论考》一文对王充其人及思想展开了多方面的批评。他认为:王充以追求知识为目的,在他的人格和思想中,人伦道德的观念非常薄弱;王充的命定论彻底否定人之行为与结果的因果关系... 详细信息

王充的《论衡》在中国哲学史上受到太高的评价,但徐复观《王充论考》一文对王充其人及思想展开了多方面的批评。他认为:王充以追求知识为目的,在他的人格和思想中,人伦道德的观念非常薄弱;王充的命定论彻底否定人之行为与结果的因果关系;王充有疾虚妄、求真实的学问要求,但没有得到立真破妄的结果;王充是一位矜才负气的乡曲之士,他的乡曲之见限制了他展望时代政治和学术的视野。他的解释,并不只是建构王充的思想体系,而且重视揭示王充的个性人格和人生遭遇对其思想形成的重要影响。

关键词：王充徐复观乡曲之士伦理道德命定论

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俗知与真知:庄子的知识论新释

中南民族大学学报（人文社会科学版） 2022年第1期42卷 171-180,188页

作者：刘国民中国社会科学院大学文学院北京100089

庄子的知识论丰富而复杂。学者多认为,庄子怀疑进而否定世人之俗知,而崇尚真人之真知;真知即体道之知,只有抛弃世人的感性和理性的认知方法及其知识,才能直觉体证本原之大道。因此,世人之俗知与真人之真知完全地对立、割裂开来,且真知... 详细信息

庄子的知识论丰富而复杂。学者多认为,庄子怀疑进而否定世人之俗知,而崇尚真人之真知;真知即体道之知,只有抛弃世人的感性和理性的认知方法及其知识,才能直觉体证本原之大道。因此,世人之俗知与真人之真知完全地对立、割裂开来,且真知及直觉的方式颇有神秘性。俗知分为事实之知与价值之知,庄子质疑进而否定事实之知的真实性、确定性,质疑进而否定价值之知的普遍性、确定性;庄子之真知不是在人世间获得真实性、普遍性的知识,也不是齐之玄知,而是忘知、无知;真人通过忘的工夫彻底地忘却一切知识,心虚静虚无,不识自我,不识天地万物,从而与天地万物混而为一,即回归原初浑沌未分或混而为一的存在形态,即向大道的回归,即体道。真人彻底地消解了自己的主体性,一方面自我养心养神,另一方面万物自生自成自毁。

关键词：庄子俗知真知无知