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Th17/Treg balance and macrophage polarization ratio in lower extremity arteriosclerosis obliterans

作者： GAO Si-ze NI Bang-fa ZHANG Gui-ying XIAO Cai-jin liu cun-xiong CHEN Zhe NIE Peng liu Chao ZHAO Chang-jun College of Physics Science and Engineering Technology Guangxi University

This system is designed to pick up sound signals from large volume,low-threshold energy, low-background superheated droplets bubble detectors.A sound-sensitive bubble detector is composed of a container filled with a mixture of superheated droplets and gel,a temperature and pressure control system,and an audio acquisition system attached on the outer surface of the *** superheated droplets are in a metastable and superheated state at ambient temperature and *** the outside

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Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 127-136,I0006-I0009页

作者： Zhen-Zhen Li Min liu xiong-Hui He Zhen-Dong liu Zhan-Xiang Xiao Hao Qian You-Fei Qi cun-Chuan Wang Department of Metabolic and Bariatric Surgery The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong Province510632China Department of Vascular Surgery Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China Department of Physical Examination Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China Department of Gastrointestinal Surgery Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China

Objective:To explore the balance of peripheral blood T helper 17 cells/regulatory T cell(Th17/Treg)ratio and the polarization ratio of M1 and M2 macrophages in lower extremity arteriosclerosis obliterans(ASO).Methods:A rat model of lower extremity ASO was established,and blood samples from patients with lower extremity ASO before and after surgery were *** was used to detect interleukin 6(IL-6),IL-10,and ***-time RCR and Western blot analyses were used to detect Foxp3,IL-6,IL-10,and IL-17 ***,flow cytometry was applied to detect the Th17/Treg ratio and M1/M2 ***:Compared with the control group,the iliac artery wall of ASO rats showed significant hyperplasia,and the concentrations of cholesterol and triglyceride were significantly increased(P<0.01),indicating the successful establishment of ***,the levels of IL-6 and IL-17 in ASO rats were pronouncedly increased(P<0.05),while the IL-10 level was significantly decreased(P<0.05).In addition to increased IL-6 and IL-17 levels,the mRNA and protein levels of Foxp3 and IL-10 in ASO rats were significantly decreased compared with the control *** Th17/Treg and M1/M2 ratios in the ASO group were markedly increased(P<0.05).These alternations were also observed in ASO *** endovascular surgery(such as percutaneous transluminal angioplasty and arterial stenting),all these changes were significantly improved(P<0.05).Conclusions:The Th17/Treg and M1/M2 ratios were significantly increased in ASO,and surgery can effectively improve the balance of Th17/Treg,and reduce the ratio of M1/M2,and the expression of inflammatory factors.

关键词： Lower extremity arteriosclerosis Regulatory T cells Regulatory B cells Inflammatory factors M1 macrophages M2 macrophages

Bilayer solid-electrolyte interphase structure enables a 440 Wh kg^(-1) lithium metal pouch cell to achieve 130 cycles

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Science China Chemistry 2024年第3期67卷 751-752页

作者： xiong liu Chaojiang Niu School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China

Lithium(Li) metal has been considered one of the most promising anodes due to its high theoretical capacity, lightweight and low electrochemical potential. The cell-level energy density of rechargeable lithium metal batteries(LMBs) is expected to surpass 500 Wh kg^(-1) after replacing the graphite anode in lithium-ion batteries [1].

关键词： lithium electrolyte layer

Hole mobility enhancement in monolayer WSe2 p-type transistors through molecular doping

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Science China(Information Sciences) 2024年第6期67卷 207-213页

作者： Shiyuan liu xiong xiong Xin WANG Xinhang SHI Ru HUANG Yanqing WU School of Integrated Circuits and Beijing Advanced Innovation Center for Integrated Circuits Peking University Wuhan National High Magnetic Field Center and School of Integrated Circuits Huazhong University of Science and Technology

Two-dimensional （2D） transition metal dichalcogenide （TMDC） semiconductor materials exhibit extraordinary electrical properties,holding promise for the realization of next-generation complementary metal-oxide-semiconductor （CMOS） devices at ultimate ***,constrained by effective device doping strategies,the hole mobility and device performance of tungsten diselenide （WSe2） p-type transistors,especially monolayer chemical vapor deposition （CVD）-grown WSe2,have not met *** this paper,an effective performance enhancement of monolayer WSe2p-type transistor was achieved through a molecular doping *** monolayer WSe2directly on SiO2back-gated substrates and leveraging energy band alignment design,4-nitrobenzenediazonium tetrafluoroborate （4-NBD） molecular dopant with a concentration of 10 m M was utilized to modulate the Fermi level position of monolayer WSe2for hole *** devices demonstrated a more than 98%increase in hole mobility,reaching up to 97 cm2·V-1·s-1while maintaining the current on/off ratio of *** p-type WSe2transistors with 1μm channel length exhibit a high drive current surpassing 176μA·μm-1,exceeding previous CVD-WSe2devices with similar channel *** straightforward and effective approach to improving the electrical performance of WSe2transistors paves the way for advanced logic technologies based on transition metal dichalcogenide semiconductors.

关键词： CVD-grown WSe$_2$ molecular doping 4-NBD p-type transistors hole mobility

Exploring the Core-shell Structure of BaTiO3-based Dielectric Ceramics Using Machine Learning Models and Interpretability Analysis

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 561-569页

作者：孙家乐 xiong Peifeng 郝华 liu Hanxing State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Material Science and EngineeringInternational School of Material Science and EngineeringWuhan University of TechnologyWuhan 430070China Sanya Science and Education Innovation Park Wuhan University of TechnologySanya 572000China Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory Xianhu Hydrogen ValleyFoshan 528200China

A machine learning(ML)-based random forest(RF)classification model algorithm was employed to investigate the main factors affecting the formation of the core-shell structure of BaTiO_(3)-based ceramics and their interpretability was analyzed by using Shapley additive explanations(SHAP).An F1-score changed from 0.8795 to 0.9310,accuracy from 0.8450 to 0.9070,precision from 0.8714 to 0.9000,recall from 0.8929 to 0.9643,and ROC/AUC value of 0.97±0.03 was achieved by the RF classification with the optimal set of features containing only 5 features,demonstrating the high accuracy of our model and its high *** the interpretability analysis of the model,it was found that the electronegativity,melting point,and sintering temperature of the dopant contribute highly to the formation of the core-shell structure,and based on these characteristics,specific ranges were delineated and twelve elements were finally obtained that met all the requirements,namely Si,Sc,Mn,Fe,Co,Ni,Pd,Er,Tm,Lu,Pa,and *** the process of exploring the structure of the core-shell,the doping elements can be effectively localized to be selected by choosing the range of features.

关键词： machine learning BaTiO_(3) core-shell structure random forest classifier

Light People:Professor Laura Na liu

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Light(Science & Applications) 2024年第2期13卷 184-189页

作者： Hui Wang cun Yu Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences130033ChangchunChina

Editorial The DNA nanotechnology outlines a new chapter in biological sciences,opening a new era of scientific and technological advancements.A pioneer of DNA nanotechnology,Professor liu from the University of Stuttgart in Germany,our latest Light People,has been working at the interface,where nanophotonics meets biology and *** the path of scientific explorations.

关键词： chemistry. advancement pioneer

Facile preparation of Fe/N-based biomass porous carbon composite towards enhancing the thermal decomposition of DAP-4

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Defence Technology（防务技术） 2024年第1期31卷 288-294页

作者： Er-hai An Xiao-xia Li cun-juan Yu Ying-xin Tan Zi-jun Fan Qing-xia Li Peng Deng xiong Cao School of Environment and Safety Engineering North University of ChinaTaiyuan030051PR China College of Safety and Emergency Management Engineering Taiyuan University of Science and TechnologyTaiyuan030024PR China

Fe/N-based biomass porous carbon composite(Fe/N-p Carbon) was prepared by a facile high-temperature carbonization method from biomass,and the effect of Fe/N-p Carbon on the thermal decomposition of energetic molecular perovskite-based material DAP-4 was *** porous carbonaceous materials was considered as the micro/nano support layers for in situ deposition of Fe/N ***/Np Carbon was prepared simply by the high-temperature carbonization *** was found that it showed the inherent catalysis properties for thermal decomposition of *** heat release of DAP-4/Fe/N-p Carbon by DSC curves tested had increased slightly,compared from DAP-4/Fe/N-p *** decomposition temperature peak of DAP-4 at the presence of Fe/N-p Carbon had reduced by 79°C from384.4°C(pure DAP-4) to 305.4°C(DAP-4/Fe/N-p Carbon-3).The apparent activation energy of DAP-4thermal decomposition also had decreased by 29.1 J/*** possible catalytic decomposition mechanism of DAP-4 with Fe/N-p Carbon was proposed.

关键词： Biomass materials Porous carbon DAP-4 Thermal decomposition Facile method

Copper-coated Porous Polyimide as Ultralight and Safe Current Collectors for Advanced LIBs

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Chinese Journal of Polymer Science 2024年第4期42卷 521-531页

作者： cun-Sheng liu Jun-Qi Hu Ting-Ting Mao Song-Yi Liao Ru-Ming Feng Yi-Dong liu Yong-Gang Min School of Materials and Energy Guangdong University of TechnologyGuangzhou510006China College of Chemistry and Chemical Engineering Zhongkai University of Agriculture and EngineeringGuangzhou510225China Shanwei Branch of Advanced Energy Science and Technology Guangdong Laboratory Shanwei516600China

Metallic copper is widely used as current collector(CC) for graphite anode of lithium-ion batteries(LIBs) due to its high electrical conductivity and electrochemical stability. However, the large volume density of commercial copper foil(~8.9 g·cm^(-3)) limits the increase of energy density of battery. Here, copper-coated porous polyimide(Cu@PPI) was prepared by vacuum evaporation as collector for the graphite anode. The sandwich structure connects the copper metal on both sides of the collector with excellent electrical conductivity. Compared to commercial Cu foil, Cu@PPI has lighter mass(≤3.9 mg for disc of 12 mm diameter versus 9.9 mg of ~10 μm Cu foil) and lower volume density(≤3.3 g·cm^(-3)). In addition, the porous structure allows of better adhesion of reactive substances and electrochemical properties than pure Cu foils. It is estimated that the energy density of Cu@PPI should be much higher than that of Cu foil. This strategy should be applicable for other current collectors.

关键词： Copper-coated Vacuum evaporation Porous polyimide(PPI) Current collector(CC) LIBs

On the Surface Helium Abundance of B-type Hot Subdwarf Stars from the WD+MS Channel of Type Ia Supernovae

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Research in Astronomy and Astrophysics 2024年第5期24卷 21-27页

作者： Rui-Jie Ji Xiang-cun Meng Zheng-Wei liu Yunnan Observatories Chinese Academy of SciencesKunming 650216Kunming 650216China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China International Centre of Supernovae(ICESUN) Yunnan Key LaboratoryKunming 650216China

The origin of intermediate helium (He)-rich hot subdwarfs is still *** studies have suggested that some surviving Type Ia supernovae (SNe Ia) companions from the white dwarf+main-sequence (WD+MS)channel may contribute to the intermediate He-rich hot ***,previous studies ignored the impact of atomic diffusion on the post-explosion evolution of surviving companion stars of SNe Ia,leading to the aspect that they could not explain the observed surface He abundance of intermediate He-rich hot *** this work,by taking the atomic diffusion and stellar wind into account,we trace the surviving companions of SNe Ia from the WD+MS channel using the one-dimensional stellar evolution code MESA until they evolve into hot *** find that the surface He-abundances of our surviving companion models during their core He-burning phases are in a range of-1■log(N_(He) N_(H))■0,which are consistent with those observed in intermediate He-rich hot *** seems to further support the notion that it is possible for surviving companions of SNe Ia in the WD+MS channel to form some intermediate He-rich hot subdwarfs.

关键词： (stars:)subdwarfs-atomic processes-diffusion

Deep neural network-enabled battery open-circuit voltage estimation based on partial charging data

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Journal of Energy Chemistry 2024年第3期90卷 120-132,I0005页

作者： Ziyou Zhou Yonggang liu Chengming Zhang Weixiang Shen Rui xiong State Key Laboratory of Mechanical Transmission for Advanced Equipment&College of Mechanical and Vehicle Engineering Chongqing UniversityChongqing 400000China Department of Vehicle Engineering School of Mechanical EngineeringBeijing Institute of TechnologyBeijing 100081China Department of Electrical Engineering Harbin Institute of TechnologyHarbin 150000HeilongjiangChina School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyHawthornVictoria 3122Australia

Battery management systems(BMSs) play a vital role in ensuring efficient and reliable operations of lithium-ion *** main function of the BMSs is to estimate battery states and diagnose battery health using battery open-circuit voltage(OCV).However,acquiring the complete OCV data online can be a challenging endeavor due to the time-consuming measurement process or the need for specific operating conditions required by OCV estimation *** addressing these concerns,this study introduces a deep neural network-combined framework for accurate and robust OCV estimation,utilizing partial daily charging *** incorporate a generative deep learning model to extract aging-related features from data and generate high-fidelity OCV *** analysis is employed to identify the optimal partial charging data,optimizing the OCV estimation precision while preserving exceptional *** validation results,using data from nickel-cobalt-magnesium(NCM) batteries,illustrate the accurate estimation of the complete OCV-capacity curve,with an average root mean square errors(RMSE) of less than 3 *** this level of precision for OCV estimation requires only around 50 s collection of partial charging *** validations on diverse battery types operating under various conditions confirm the effectiveness of our proposed *** cases of precise health diagnosis based on OCV highlight the significance of conducting online OCV *** method provides a flexible approach to achieve complete OCV estimation and holds promise for generalization to other tasks in BMSs.

关键词： Lithium-ion battery Open-circuit voltage Health diagnosis Deep learning