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Down-regulation of SEIPIN transcription attenuated the triacylglycerol accumulation in Nannochloropsis oceanica

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Journal of Oceanology and Limnology 2025年第1期43卷 187-195页

作者： Lixian liu Li GUO Hang liu Xiaohui PAN Yanan zong Leili FENG Guanpin YANG College of Marine Life Sciences Ocean University of ChinaQingdao 266003China Institutes of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China Key Laboratory of Marine Genetics and Breeding of Ministry of Education Ocean University of ChinaQingdao 266003China MoE Laboratory of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China

Abnormal content of protein SEIPIN causes Berardinelli-Seip congenital lipodystrophy type 2(BSCL2)in *** studies have shown that Arabidopsis thaliana has evolved three SEIPIN homologs,determining the fusion and size of lipid *** oceanica is a model oleaginous microalga with the accumulation potential of fatty *** believe that the SEIPIN homolog if any in *** should function as it does in humans,plant among *** this study,we identified a homologous gene of SEIPIN in ***,constructed a bacterial plasmid containing the elements controlling the transcription of its complete antisense RNA,and integrated the linearized plasmid into the *** *** obtained a transformant in which the abundance of SEIPIN transcript is significantly *** cytometry analysis showed that the triacylglycerol(TAG)content of the transformant is significantly lower than that of the wild type(WT).Transcriptomic analysis showed that the down-regulation of SEIPIN transcript abundance could affect the protein functioning in endoplasmic reticulum(ER),implying that SEIPIN gene can function in *** in a similar way to that in ***.

关键词： Nannochloropsis oceanica antisense RNA SEIPIN neutral lipid

Radiation belt electron wisp inside South Atlantic Anomaly due to terrestrial VLF transmitter observed by MSS-1

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Science China Earth Sciences 2025年第2期68卷 538-548页

作者： Yixin SUN Ying liu Qiugang zong Yixin HAO Hong ZOU Yuguang YE Institute of Space Physics and Applied Technology Peking UniversityBeijing 100871China State Key Laboratory of Lunar and Planetary Science Macao University of Science and TechnologyMacao 999078China Max Planck Institute for Solar System Research Goettingen 37077Germany

The South Atlantic Anomaly represents a region within near-Earth space characterized by a significantly weaker geomagnetic field and a higher flux of energetic particles compared to other areas. It is a space weather hazards to Low-EarthOrbit satellites. There has been evidence that the Very Low Frequency(VLF) waves from the powerful ground VLF radio transmitter in Australia, known as NWC, have the capacity to scatter energetic electrons' pitch angle in the inner radiation *** scattering directs electrons into the drift loss cone, forms a “wisp”, characterized by its peak intensity outside the South Atlantic Anomaly(SAA), and a “rift” exhibiting minimal intensity within SAA. Our findings mark the initial observation of a“wisp” precipitation, an unusual occurrence with peak intensity detected inside the SAA, observed via the Macao Science Satellite-1. Enabled by the Medium-energy Electron Spectrometer onboard Macao Science Satellite-1, we were able to comprehensively measure the full pitch angle distribution at Low-Earth-Orbit. This allowed us to attribute the “wisp” within the anomaly to a specific pitch angle range just outside the drift loss cone, a measurement unattainable by previous satellites. This“wisp” occurrence aligns with previous model predictions, despite being overlooked. Moreover, we distinguished between the trapped and precipitating electron populations. Directly derived from the ratio of these populations, our analysis revealed that approximately 2%-5% of trapped electrons will be lost in this specific wisp due to the influence of the ground VLF *** results not only complement existing evidence of energetic electron pitch angle scattering facilitated by the ground VLF transmitter but also offer a quantitative estimation of its impact.

关键词： South Atlantic Anomaly Radiation belts Electrons precipitation VLF transmitter Wave-particle interaction

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Functional ternary salt construction enabling an in-situ Li3N/LiF-enriched interface for ultra-stable all-solid-state lithium metal batteries

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Journal of Energy Chemistry 2025年第2期101卷 68-75页

作者： Hong-Yan liu Xin-Yu liu Nan Zhang Peng-Fei Wang zong-Lin liu Jie Shu Ting-Feng Yi School of Materials Science and Engineering Northeastern University Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province School of Resources and Materials Northeastern University at Qinhuangdao Faculty of Materials Science and Chemical Engineering and Key Laboratory of Photoelectric Detection Materials and Devices of Zhejiang Province Ningbo University

Poly（ethylene oxide）-based polymer all-solid-state lithium metal batteries（ASSLBs） have received widespread attention due to their low cost,good process ability,and high energy ***,the growth of Li dendrites within polymer solid-state electrolytes damages the reversibility of Li anodes and still impedes their widespread *** efficient strategy is to construct a superior solid electrolyte ***,a stable interface enriched with Li3N and LiF is in-situ formed between Li anode and a terna ry salt *** terna ry salt electrolyte is innovatively designed by introducing lithium bis（trifluoromethane sulfonyl）imide（LiTFSI）,lithium bis（fluorosulfonyl）imide（LiFSI）,and LiNO3to poly（ethylene oxide） *** characterization indicates that LiNO3and LiFSI contribute to forming a Li3N-LiF-enriched interface and meanwhile LiTFSI ensures excellent ***,among various Li compound components,Li3N has high ionic conductivity,which is beneficial for reducing overpotential,while LiF has high interfacial energy which can enhance nucleation energy and suppress the formation of Li *** experimental results show that ASSLBs coupled with LiFePO4cathode display extremely excellent cycle stability approximately 2200 cycles at 2 C,with a final and corresponding discharge specific capacity of 96.7 mA h g-1. Additionally,a schematic illustration of the working mechanism for the Li3N-LiF interface is proposed.

关键词： All-solid-state lithium metal batteries In-situ SEI Lithium dendrite PEO (LiTFSI) Solid electrolyte

Confined electric field in nano-sized channels of ionic porous framework towards unique adsorption selectivity

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Chinese Chemical Letters 2025年第02期36卷 465-469页

作者： Congyan liu Xueyao Zhou Fei Ye bin Jiang Bo liu School of Chemistry and Materials Science University of Science and Technology of China

Efficient selective adsorption and separation using porous frameworks are critical in many industrial processes,where adsorption energy and dynamic diffusion rate are predominant factors governing *** are highly susceptible to framework charge,which plays a significant role in selective ***,ionic porous frameworks can be divided into two *** of them is composed of a charged backbone and counter *** framework with zwitterionic channels is another *** is composed of regular and alternating arrangements of cationic and anionic building ***,we report a hydrogen-bonded ionic framework （HIF） of{（CN3H6）2[Ti（μ2–O）(SO4)2]}_nwith 1D channel exhibits unique adsorption selectivity for Ar against N2and *** functional theory （DFT） results suggest that CO2cannot be adsorbed by HIF at the experimental temperature due to a positive adsorption free *** addition,due to a relatively large diffusion barrier at 77 K,N2molecules hardly diffuse in HIF channels,while Ar has a negligible diffusion *** unique net positively-charged space in the channel is the key to the unusual phenomena,based on DFT simulations and structural *** findings in this work proposes the new adsorption mechanism and provides unique perspective for special separation applications,such as isotope and noble gasses separations.

关键词： Adsorption Channel Guanidinium Positive electric field Selectivity

Simulations of electron zebra stripes in the inner radiation belt using a composite empirical electric field model

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Science China Earth Sciences 2025年第1期68卷 27-38页

作者： Ziyang WANG Ying liu Qiugang zong Hong ZOU Yuguang YE Xuzhi ZHOU Chao YUE Shan WANG Institute of Space Physics and Applied Technology Peking UniversityBeijing100871China State Key Laboratory of Lunar and Planetary Science Macao University of Science and TechnologyMacao999078China

The phenomenon termed“zebra stripes”manifests as regular patterns in the energy-space(L shell)spectrum of energetic electrons(ranging from tens to hundreds ke V)within the inner radiation *** structures exhibit drift-periodic behavior and commonly arise from large-scale electric field perturbations near the substorm *** this study,we introduce a composite electric field model and replicate the formation,structure,and evolution of zebra stripes using a bounce-averaged test particle code under this electric field ***-resolution measurements of energetic electrons obtained from the Van Allen Probes and the recently launched Macao Science Satellites-1 are used as initial conditions and served to validate our test particle *** analyses between observed data and simulations demonstrate our test particle method's efficacy in capturing zebra stripes'general ***,the composite model proves capable of reproducing realistic variations in the electric field within the inner radiation belt to a certain ***,subtle differences emerge in the flux strength and the positions of *** disparities primarily stem from limitations inherent in the electric field model and the initial conditions of the *** that the model represents an average case,it is conceivable that real-world scenarios may deviate from the average,thereby introducing variations in the observed phenomena.

关键词： Zebra stripes Inner radiation belt Large-scale electric fields Van Allen Probes Macao Science Satellite

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BLAKE算法的硬件实现研究

计算机学报 2012年第4期35卷 703-711页

作者：刘宗斌荆继武夏鲁宁中国科学院研究生院信息安全国家重点实验室北京100049

随着对MD5和SHA1攻击方法的提出,美国国家标准技术研究所(NIST)组织启动了SHA-3的征集计划,目前已进入第3轮.BLAKE算法进入了最后一轮竞赛,文中首先综述了BLAKE算法从提交到目前为止在硬件评估方面的状况.在此基础上优化了BLAKE压缩函数... 详细信息

随着对MD5和SHA1攻击方法的提出,美国国家标准技术研究所(NIST)组织启动了SHA-3的征集计划,目前已进入第3轮.BLAKE算法进入了最后一轮竞赛,文中首先综述了BLAKE算法从提交到目前为止在硬件评估方面的状况.在此基础上优化了BLAKE压缩函数在FPGA上实现的关键路径,并在FPGA平台上实现了BLAKE算法.和现有的BLAKE算法在FPGA上实现的吞吐率相比,文中实现结构的吞吐率又有提升.

关键词： SHA-3 BLAKE FPGA 散列函数

Multiple-stage W mineralization in the Guanfang W deposit,southeastern Yunnan Province,China:Insights from scheelite in-situ trace elemental and Sr isotopic analyses

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Acta Geochimica 2025年第1期44卷 112-127页

作者： bin Sun Yi liu Zhigang Kong Xuelong liu Xiaojun Jiang Chao Li Wenchang Li Faculty of Land Resources Engineering Kunming University of Science and TechnologyNo.727 South Jingming RoadChenggong DistrictKunming City 650093Yunnan ProvinceChina Institute of Mineral Resources Chinese Academy of Geological SciencesNo.26 Baiwanzhuang StreetXicheng DistrictBeijing 100037China

The Guanfang large-scale W deposit is located in the W polymetallic ore concentration area of Bozhushan in southeastern Yunnan,*** extensive research,the fluid evolution process of the deposit remains ambiguous,leading to controversy regarding its *** study conducted a detailed field geological survey,with systematic sampling of the KT6 orebody,to delineate mineralization *** mineralogy work,including the use of CL images of scheelite,in-situ LA-ICP-MS trace elements,and Sr isotopes,was carried out on diff erent generations of scheelite formed in various *** findings identified the evolution of fluids in the mineralization process,shedding light on the genesis of the *** study revealed four mineralization stages at the Guanfang W deposit:prograde skarn stage,retrograde skarn stage,quartz-sulfide stage,and carbonate-fluorite *** erent generations of scheelite(Sch I,Sch II,Sch III)were observed in the first three stages,displaying distinct chondrite-normalized REE *** REE of Sch I mainly substituted into the Ca site by REE^(3+)+□_(Ca),and there may be a similar substitution of Nb for REE,whereas it is not the main substitution *** REE of Sch II mainly enter the scheelite lattice in the form of REE 3++Na+,and there may be a substitution of Nb for REE *** the early stage,The REE of Sch III was mainly replaced by Nb for REE isomorphism,while in the later stage,the replacement mode of REE^(3+)+□_(Ca)coexisted with *** Mo content in scheelite,along with the corresponding Eu anomalies in both scheelite and garnet,collectively imply that the ore-forming fluids during various mineralization stages were predominantly oxidizing,with only slight reducibility observed in Sch *** in-situ Sr isotope ratios of scheelite concentrates ranged from 0.7093 to 0.7153,resembling those of the Bozhushan granite,indicating a relationship between W mineralization and *** addition,the Y/Ho ratios of scheeli

关键词： Guanfang W deposit Trace elements of scheelite In-situ Sr isotopes Southeast Yunnan

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基于DSP的便携式应力检测仪设计

仪表技术与传感器 2020年第10期 38-41页

作者：刘宗斌车华军刘宗苏江苏省特种设备安全监督检验研究院无锡分院江苏无锡461000 江苏大学江苏镇江212013 常州工学院江苏常州213022

为了实现铁磁性材料的应力检测,设计了一种基于巴克豪森(MBN)的便携式应力检测装置。该装置是以DSP微控制器为控制核心,采用巴克豪森效应检测原理,通过分析巴克豪森噪声产生的原理,建立巴克豪森噪声与铁磁性材料应力之间的关系,通过分... 详细信息

为了实现铁磁性材料的应力检测,设计了一种基于巴克豪森(MBN)的便携式应力检测装置。该装置是以DSP微控制器为控制核心,采用巴克豪森效应检测原理,通过分析巴克豪森噪声产生的原理,建立巴克豪森噪声与铁磁性材料应力之间的关系,通过分析噪声信号来计算得到铁磁性材料的应力值。实际测试结果表明,巴克豪森信号随着应力的增大而逐渐减小,通过压力标定机对系统进行标定后,将系统测得应力值与标准应力进行对比,得出系统具有较高的测量精度,相对误差不超过5%,系统具有无损检测铁磁性检测应力的优势。

关键词：铁磁性材料便携式巴克豪森 DSP

Arsenic exposure and oxidative damage to lipid,DNA,and protein among general Chinese adults:A repeated-measures cross-sectional and longitudinal study

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Journal of Environmental Sciences 2025年第1期147卷 382-391页

作者： Yongfang Zhang Min Zhou Dongming Wang Ruyi Liang Wei liu bin Wang Weihong Chen Department of Occupational and Environmental Health School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Key Laboratory of Environment and Health Ministry of Education and Ministry of Environmental Protectionand State Key Laboratory of Environmental Health(Incubating)School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Arsenic-related oxidative stress and resultant diseases have attracted global concern,while longitudinal studies are *** assess the relationship between arsenic exposure and systemic oxidative damage,we performed two repeatedmeasures among 5236 observations(4067 participants)in theWuhan-Zhuhai cohort at the baseline and follow-up after 3 *** total arsenic,biomarkers of DNA oxidative damage(8-hydroxy-2-deoxyguanosine(8-OHdG)),lipid peroxidation(8-isoprostaglandin F2alpha(8-isoPGF2α)),and protein oxidative damage(protein carbonyls(PCO))were detected for all *** we used linearmixed models to estimate the cross-sectional and longitudinal associations between arsenic exposure and oxidative ***-response curves were constructed by utilizing the generalized additive mixed models with thin plate *** adjusting for potential confounders,arsenic level was significantly and positively related to the levels of global oxidative damage and their annual increased rates in dose-response *** cross-sectional analyses,each 1%increase in arsenic levelwas associated with a 0.406%(95%confidence interval(CI):0.379%to 0.433%),0.360%(0.301%to 0.420%),and 0.079%(0.055%to 0.103%)increase in 8-isoPGF2α,8-OHdG,and PCO,*** importantly,arsenic was further found to be associated with increased annual change rates of 8-isoPGF2α(β:0.147;95%CI:0.130 to 0.164),8-OHdG(0.155;0.118 to 0.192),and PCO(0.050;0.035 to 0.064)in the longitudinal *** study suggested that arsenic exposurewas not only positively related with global oxidative damage to lipid,DNA,and protein in cross-sectional analyses,but also associated with annual increased rates of these biomarkers in dose-dependent manners.

关键词： Arsenic Oxidative stress Oxidative damage 8-isoPGF2α 8-OHdG Protein carbonyls(PCO)