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腹腔镜完全腹膜外疝修补术后血清肿的危险因素分析

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中国医师进修杂志 2022年第9期45卷 834-838页

作者：李海风战俊滕世岗尹鹏刘忠诚李梦良青岛市胶州中心医院普通外科青岛266300 同济大学附属东方医院胶州医院普通外科青岛266300 青岛市胶州中心医院麻醉科青岛266300

目的探讨影响腹腔镜完全腹膜外疝修补术后血清肿形成的危险因素。方法回顾性分析青岛市胶州中心医院2018年7月至2021年6月236例行腹腔镜完全腹膜外疝修补术患者的临床资料,分析影响术后血清肿形成的危险因素。结果 236例患者术后发生血... 详细信息

目的探讨影响腹腔镜完全腹膜外疝修补术后血清肿形成的危险因素。方法回顾性分析青岛市胶州中心医院2018年7月至2021年6月236例行腹腔镜完全腹膜外疝修补术患者的临床资料,分析影响术后血清肿形成的危险因素。结果 236例患者术后发生血清肿36例(血清肿组),发生率为15.25%;未发生血清肿200例(无血清肿组)。两组病程≥5年、阴囊疝、内环缺损≥3 cm、疝囊离断、术者手术经验0.05)。多因素Logistic回归分析结果显示,病程≥5年、阴囊疝、疝囊离断和术者手术经验<5年是影响腹腔镜完全腹膜外疝修补术后血清肿形成的独立因素(OR = 5.147、5.006、0.044和3.315,95%CI 1.513~17.516、1.845~13.583、0.008~0.240和1.029~10.679,P<0.01或<0.05)。结论病程≥5年、阴囊疝、疝囊离断和术者手术经验<5年为影响腹腔镜完全腹膜外疝修补术后血清肿形成的独立因素,术前正确评估相关危险因素有助于减少血清肿的发生。

关键词：疝缝术,疝修补手术,疝修补术腹腔镜血清肿危险因素

Study on the interaction between Jak3 and IL-2R γ using the yeast two-hybrid system

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Chinese Science Bulletin 1999年第18期44卷 1664-1669页

作者： Jinfang Zhu Wei Tang Hongbin Ji zhongcheng Zheng Xinyuan liu Shanghai Institute of Biochemistry Chinese Academy of Sciences Shanghai China

Both interleukin-2 (IL-2) receptor y subunit and non-receptor tyrosine kinase Jak3 play important roles in IL-2 physiological functions. Jak3 has been known to bind IL-2Ry and the interaction is very important for IL-2 signaling. In order to find the domains directly involved in the interaction between IL-2Ry and Jak3, various deletion mutants have been constructed

关键词： IL-2Rγ Jak3 yeast two-hybrid system interaction.

PROCESS AND PROPERTIES OF ELECTROLESS PLATING RE-Ni-B-SiC COMPOSITE COATINGS

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Acta Metallurgica Sinica(English Letters) 1995年第2期8卷 118-122页

作者： GUO zhongcheng liu Hongkang WANG Zhiyin WANG Min(Kunming Institute of Technology,Kunming. China ) Kunming Inst of Technology Kunming China

Technology and properties of electroless composite RE-Ni-B-SiC coatings have been *** show that stabilizer plys a decisive role in electroless composite Ni-B-SiC,the addition of appropriate quantity of RE(rare earth) into the Ni-B-SiC bath not only increases SiC content in composite coatings,their hardness and wear resistance but also improves crystalline fineness,Wear resistance increases with the increase of *** and wear resistance of composite coatings reach peak values a fter heat treatment at 4OO and 500℃ for 1h respectively.

关键词： electroless plating Ni-B-SiC-RE composite coating

JAK3 mediates c-myc gene expression induced by interleukin-2

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Chinese Science Bulletin 1998年第4期43卷 308-311页

作者： Zhu Jinfang Lu Linrong Ji Hongbin Zheng zhongcheng J. Thèze liu Xinyuan Chinese Acad Sci Shanghai Inst Biochem Shanghai 200031 Peoples R China Inst Pasteur Paris France

C myc gene expression can be rapidly induced by IL 2 through intracellular signal transduction which is triggered by the interaction between IL 2 and its receptor （IL 2R）. JAK3 which associates to the intracellular domain of IL2R γ may play a critical role in this process. To reveal the action of JAK3 in c myc induction, a chimeric receptor gene IL2R α/γ/Δ NJAK3 is constructed which consists of extracellular domain derived from IL 2R α subunit （IL2R α）, the transmembrane sequence derived from IL2R γ and the cytoplasmic domain derived from the catalytic domain of JAK3 （Δ NJAK3）, and then transfected this chimeric gene into mouse fibroblast cell line L929 β which had been transfected with IL2R β gene and stably expressed IL2R β in high level. In the transfectants coexpressing IL2R β and α/γ/Δ NJAK3, the stimulation of IL2 could intensively induce c myc gene expression. Because the whole cytoplasmic domain of IL2R γ which could recruit signaling molecules was replaced by JAK3 and the c myc could be still induced by IL2 in this situation, the results here gave the direct evidence demonstrating that JAK3 plays an important role in c myc gene expression induced by IL2.

关键词： interleukin 2(IL 2) JAK3(Janus Kinase 3) c myc gene signal transduction.

2012-2017年北京市昌平区流感相关超额流感样病例数估计

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国际病毒学杂志 2018年第3期25卷 174-179页

作者：李飒刘重程高进玺王瑞琴蔡旭金文军唐雅清北京市昌平区疾病预防控制中心传染病与地方病控制科 102200

目的估计2012-2017年北京市昌平区流感相关的超额流感样病例数（influenza—like illness cases，ILI）。方法使用昌平区二级及以上医疗机构ILI监测数据，分别拟合传统Serfling回归模型和调整Serfling回归模型，分年龄组估计流感相关超... 详细信息

目的估计2012-2017年北京市昌平区流感相关的超额流感样病例数（influenza—like illness cases，ILI）。方法使用昌平区二级及以上医疗机构ILI监测数据，分别拟合传统Serfling回归模型和调整Serfling回归模型，分年龄组估计流感相关超额ILI数。结果调整Serfling回归模型结果显示，全人群中，2012-2013年度的流行周为2012年的第52周至次年的第2周、2013-2014年度为2013年的第52周至次年的第6周、2014-2015年度为2014年的第46周至次年第3周、2015-2016年度为2015年的第52周至次年第14周、2016-2017年度为2016年的第47周至次年第6周，年均流行周数为10（范围：4．15）周。各年度流行周的超额流感样病例数分别为598（95％CI：207-719）、1517（95％CI：1070-1964）、2883（95％CI：2243-3522）、5027（95％CI：4067-5986）和3126（95％C1：2291-3961）例，年均超额ILI数为2630（95％C1：1976-3230）例，占同期总ILI监测数的58．7％。传统Serfling回归模型估计〈5岁、5-59岁和全人群的结果基本一致。结论调整Serfling回归模型对于超额ILI的估算结果较传统Serfling模型更为精确。每个流行季，流感的流行均导致数千人至数万人的超额ILI数和门急诊就诊量。

关键词：流感回归分析人群监测超额流感样病例数

Interleukin-2 mediates the peripheral analgesia of interferon alpha

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Chinese Science Bulletin 1999年第3期44卷 243-246页

作者： Li Li Qiwei Zhai Wei Tang Tong Wu zhongcheng Zheng Xinyuan liu Chinese Acad Sci Shanghai Inst Biochem Shanghai 200031 Peoples R China

Interferon-α (IFN-α) and interleukin-2 (IL-2) are crucial cytokines in immune system. They also play an important role in nerve system. It has been reported that IL-2 can induce the central analgesia. It is demonstrated that IFN-α also can induce the peripheral analgesia, which can be blocked by naloxone as IL-2. Furthermore, the analgesic effect of IFN-α is reversible by monoclonal anti-IL-2 antibody. In vitro experiments show that IFN-α significantly increases the production of IL-2 in a dose dependent manner. These data suggest that IL-2 mediates the peripheral analgesia of IFN-α.

关键词： IFN-α IL-2 analgesia.

Impacts of CaO Solid Particles in Carbon Dioxide Absorption Process from Ship Emission with NaOH Solution

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Journal of Shanghai Jiaotong university(Science) 2018年第2期23卷 320-326页

作者： WANG zhongcheng liu Xiaoyu ZHOU Peilin XU Leping Merchant Marine College Shanghai Maritime University Shanghai 201306 China Naval Architecture Ocean and Marine Engineering College University of Strathclyde Glasgow G11XQ UK

CO_2 emitted from ship exhaust is one of the major sources of atmospheric pollution. In order to reduce ship CO_2 emissions, this paper comes up with the idea of recovering CO_2 from ship exhaust by Na OH solution and improves the absorption rate by adding Ca O solid particles. The effect mechanism of Ca O solid particles on CO_2 absorption efficiency is analyzed in detail, and the mathematical model is deduced and the Ca O enhancement factor is calculated through experiments. Experiment result demonstrates that the effect of CaO solid particles on the absorption of CO_2 in alkali solution is significant. The absorption rate of pure CO_2 gas,the simulated ship exhaust gas and 6135 AZG marine diesel engine emission can be increased by 10%, 15.85% and10.30%, respectively. So it can be seen that CaO solid particles play an important role in improving the absorption efficiency of ship CO_2 emission.

关键词： environmental protection diesel emissions CO2 absorption CaO particulate matter enhancement factor

PROPERTIES OF ELECTRODEPOSITED AMORPHOUS Ni-W-P-SiC COMPOSITE COATINGS

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Acta Metallurgica Sinica(English Letters) 1996年第1期9卷 44-48页

作者： GUO zhongcheng liu Hongkang WANG Zhiyin WANG Min(Department of Metallurgy,Kunming institute of Technology,Kunming 650093,China) Kunming Inst of Technology Kunming China

The Effects of heat treatment temperature on the hardness,wear resistance and structure of the amorphous Ni-W-P-SiC composite coatings have been *** results show that Ni-W-P-SiC composite coatings are amorphous under 300℃, partially crystalline at 300-400℃,and crystalline when heat treatment temperature reaches 400℃,the crystals being fine Ni3P phase *** hardness,wear resistance and the crystallization temperature of the composite coatings increase when an additive is added into the *** hardness and wear resistance of the coatings increase with increasing heat treatment temperature,and they will reach their peak values when the heat treatment temperature reaches 400℃.Corrosion experiment indicates that the corrosion resistance of amorphous Ni-W-P-SiC composite coatings in various kinds of corrosive media except nitric acid is better than that of stainless steel *** electron microscopy observation shows that the additive has no effect on the surface appearance of the coatings,but the current density and the pH value have considerable effects on the surface appearance.

关键词： electrodeposition Ni-W-P-SiC composite coating amorphous

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室上性心动过速射频消融术终点的判定与确认

天津医药 1996年第3期24卷 135-138页

作者：李广平李忠诚刘洪徐延敏张一梅天津医科大学第二医院 300211

对47例室上性心动过速患者做了射频消融术,其中1例未成功,计46例。房室结双径路15例,隐匿性房室旁路17例,W-P-W综合征14例。46例病人中,右侧隐匿性旁路1例,B型W-P-W综合征3例,A型合并B型W-P-W综合征1例。结果提示,房室结双径路应选择慢... 详细信息

对47例室上性心动过速患者做了射频消融术,其中1例未成功,计46例。房室结双径路15例,隐匿性房室旁路17例,W-P-W综合征14例。46例病人中,右侧隐匿性旁路1例,B型W-P-W综合征3例,A型合并B型W-P-W综合征1例。结果提示,房室结双径路应选择慢径消融,消融后一旦慢径路消失,即表明消融成功。而波消失或心室起搏时表现室房分离或递减传导,即为旁路消融成功的标志。房室结双径路消融成功后一般不必要巩固放电,而旁路消融成功后可以再巩固放电1～2次。消融术后系统的电生理检查是必要的。

关键词：射频消融术终点判定心动过速