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颈淋巴结阴性的甲状腺乳头状微灶癌中央组淋巴结转移的危险因素分析

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中国临床药理学杂志 2015年第2期31卷 96-98页

作者：杨杰曹树立刘同喜何彪宁波市第九医院普外科浙江宁波315020 宁波市第二医院普外科浙江宁波315020

目的了解甲状腺乳头状微灶癌(PTMC)气管旁淋巴结转移情况,探讨临床颈淋巴结阴性(c N0)PTMC患者发生Ⅵ区淋巴转移的危险因素。方法回顾性分析行患侧甲状腺根治性切除+颈Ⅵ区淋巴清扫术的120例c N0PTMC患者临床资料。根据术后病理检查分... 详细信息

目的了解甲状腺乳头状微灶癌(PTMC)气管旁淋巴结转移情况,探讨临床颈淋巴结阴性(c N0)PTMC患者发生Ⅵ区淋巴转移的危险因素。方法回顾性分析行患侧甲状腺根治性切除+颈Ⅵ区淋巴清扫术的120例c N0PTMC患者临床资料。根据术后病理检查分为Ⅵ区淋巴结转移组(40例)和未转移组(80例),并对可能的危险因素进行分析研究。结果 PTMC颈Ⅵ区淋巴结转移率为33.3%,单侧癌灶部位(P<0.05)、甲状腺包膜侵犯(P<0.05)、单侧多灶性PTMC(P<0.01)为Ⅵ区淋巴结转移的危险因素。结论 c N0PTMC有较高的颈部中央组淋巴结转移率,在切除甲状腺的同时清扫颈Ⅵ区的淋巴结是十分必要的,尤其有相关危险因素者。

关键词：甲状腺乳头状微灶癌中央组淋巴结颈淋巴结转移 Logistic回归模型

Boosting hydrocarbon conversion via Cu-doping induced oxygen vacancies on CeO2 in CO2 electroreduction

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Journal of Energy Chemistry 2025年第1期100卷 66-76页

作者： Lei Xue tong Shi Chenhui Han Heng Zhang Fenrong liu Haorun Li Yan Wang xiaojun Gu Shanghong Zeng Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials School of Chemistry and Chemical Engineering Inner Mongolia University State Key Laboratory of Coal Conversion Institute of Coal Chemistry Chinese Academy of Sciences Institute of Catalysis Department of Chemistry Zhejiang University National Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization Baotou Research Institute of Rare Earths

Conversion of CO2back to hydrocarbons is the most direct way of closing the“carbon cycle”,and its significance is further enlarged if this process is driven by renewable energies such as ***,precisely controlling the product selectivity towards hydrocarbons against the competitive hydrogen evolution remains challenging,especially for Cu-based ***,we report a novel defect engineering strategy,by which Cu-doping-induced oxygen vacancies on CeO2nanorods were effectively created,with adjustable vacancy/Cu *** resulting optimum catalyst shows up to 79% catalytic current density to hydrocarbons （excluding CO）,with 49% faradaic efficiency to *** and density functional theory unveil that the ratio between oxygen vacancy and Cu affects significantly the formation of*CHO and activation of H2O,which leads to the following deep hydrogenation to *** findings may spur new insights for designing and developing more controllable chemical process relevant to CO2utilization.

关键词： Oxygen vacancy Hydrocarbon production Reaction mechanism

35CrMo与Q345D异种材料焊接工艺技术

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装备制造技术 2012年第5期 77-78页

作者：唐莎刘同喜中国葛洲坝集团机械船舶有限公司机械厂湖北宜昌443002 中国葛洲坝集团设备中心湖北宜昌443002

针对异种材料焊接时品质往往难以保证的问题,对35CrMo与Q345D材料焊接做了阐述,对其难点进行了具体的分析和研究,并采取了相应的措施,为类似材料的焊接提供了可借鉴的理论依据。

关键词： 35CrMo Q345D 焊接工艺

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门型移动式启闭机维护保养及故障处理

装备制造技术 2017年第8期 168-170页

作者：刘同喜唐莎中国葛洲坝集团股份有限公司湖北武汉443000 中国葛洲坝集团机械船舶有限公司湖北宜昌443007

列举了门型移动式启闭机的日常维护、定期维护、故障处理及注意事项,具有一定的借鉴意义。

关键词：门型移动式启闭机日常维护定期维护故障处理、注意事项

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胰腺闭合性损伤48例分析

新乡医学院学报 2005年第3期22卷 273-273,277页

作者：刘同喜鲁朝敏新乡医学院第三附属医院普外科河南新乡453003

目的探讨胰腺闭合性损伤早期诊断的方法和术式与预后关系。方法对48例胰腺不同程度闭合性损伤的诊断和治疗进行回顾和分析。结果48例患者中治愈46例(96%),并发胰瘘3例,十二指肠瘘1例,腹腔内感染2例,应激性溃疡合并上消化道出血1例,死亡2... 详细信息

目的探讨胰腺闭合性损伤早期诊断的方法和术式与预后关系。方法对48例胰腺不同程度闭合性损伤的诊断和治疗进行回顾和分析。结果48例患者中治愈46例(96%),并发胰瘘3例,十二指肠瘘1例,腹腔内感染2例,应激性溃疡合并上消化道出血1例,死亡2例(4%)。结论胰腺闭合性损伤早期诊断及手术方式的选择是减少并发症及死亡率的关键。

关键词：胰腺损伤诊断临床分析

弥漫性肺间质疾病中医证候要素量化诊断工具的初步研究

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中华中医药杂志 2023年第6期38卷 2823-2827页

作者：刘锡曈刘强张宗学焦以庆王玉光首都医科大学附属北京中医医院北京100010 世界中医药学会联合会评价中心北京100101

目的:初步探索弥漫性肺间质疾病中医证候要素量化诊断工具的建立方法。方法:在文献整理和专家问卷调查的基础上,采集105例弥漫性肺间质疾病患者的临床四诊和辨证信息,初步分析证候要素分布规律,经过诊断条目筛选,采用Fisher判别分析法... 详细信息

目的:初步探索弥漫性肺间质疾病中医证候要素量化诊断工具的建立方法。方法:在文献整理和专家问卷调查的基础上,采集105例弥漫性肺间质疾病患者的临床四诊和辨证信息,初步分析证候要素分布规律,经过诊断条目筛选,采用Fisher判别分析法构建量化诊断模型,采用回代法对其进行初步验证。结果:构建的证候要素量化诊断工具对气虚、痰和血瘀的临床诊断符合率>90%,且敏感度和特异度较高。阴虚证诊断符合率达到85.71%,但敏感度偏低。湿证诊断符合率相对较低。结论:构建的弥漫性肺间质疾病中医证候要素量化诊断工具具备可行性,但对个别证候要素诊断能力不足,需进一步方法学提升。

关键词：弥漫性肺间质疾病证候要素条目筛选德尔菲法专家问卷判别分析量化诊断

Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu xiaoling liu Biao Meng Tao Chen Yu Han Jun Wang Shibo xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Single atom catalyst Synergy effect Carbon catalyst Electrocatalysis

Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3273-3286页

作者： Shiming Li Jianfeng Li Guoliang Chen Tao Lin Penghui Zhang Kuileung tong Ningning Chen Shaoyu liu Shenzhen Key Laboratory of Bone Tissue Repair and Translational Research Department of Orthopedic SurgeryThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdong ProvinceChina Department of Orthopedic Surgery The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedics and Traumatology Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedic Surgery The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord *** exosomes are recognized as playing a pivotal role in neural stem cells exocrine function,their precise function in spinal cord injury remains *** investigate the role of exosomes generated following neural stem cells necroptosis after spinal cord injury,we conducted singlecell RNA sequencing and validated that neural stem cells originate from ependymal cells and undergo necroptosis in response to spinal cord ***,we established an in vitro necroptosis model using neural stem cells isolated from embryonic mice aged 16-17 days and extracted *** results showed that necroptosis did not significantly impact the fundamental characteristics or number of *** sequencing of exosomes in necroptosis group identified 108 differentially expressed messenger RNAs,104 long non-coding RNAs,720 circular RNAs,and 14 microRNAs compared with the control *** of a competing endogenous RNA network identified the following hub genes:tuberous sclerosis 2(Tsc2),solute carrier family 16 member 3(Slc16a3),and forkhead box protein P1(Foxp1).Notably,a significant elevation in TSC2 expression was observed in spinal cord tissues following spinal cord ***2-positive cells were localized around SRY-box transcription factor 2-positive cells within the injury ***,in vitro analysis revealed increased TSC2 expression in exosomal receptor cells compared with other *** assessment of cellular communication following spinal cord injury showed that Tsc2 was involved in ependymal cellular communication at 1 and 3 days post-injury through the epidermal growth factor and midkine signaling *** addition,Slc16a3 participated in cellular communication in ependymal cells at 7 days post-injury via the vascular endothelial growth factor and macrophage migration inhibitory factor signaling

关键词： cellular communication competing endogenous RNA exosomes Foxp1 necroptosis neural stem cells Slc16a3 spinal cord injury transcriptome sequencing Tsc2

喙突下臂丛神经阻滞用于骨科上肢手术的效应观察

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临床骨科杂志 2014年第6期17卷 721-723页

作者：刘同喜孙东岳平凉市第二人民医院麻醉科甘肃平凉744000

目的：观察用神经刺激仪定位喙突下臂丛神经阻滞的临床效应。方法将80例ASA Ⅰ-Ⅱ级骨科肘关节以下部位择期手术患者按照随机数字表达法分为喙突下组（A组）和腋路组（B组），每组40例。分别应用神经刺激仪进行喙突下和腋路途径施行臂... 详细信息

目的：观察用神经刺激仪定位喙突下臂丛神经阻滞的临床效应。方法将80例ASA Ⅰ-Ⅱ级骨科肘关节以下部位择期手术患者按照随机数字表达法分为喙突下组（A组）和腋路组（B组），每组40例。分别应用神经刺激仪进行喙突下和腋路途径施行臂丛神经阻滞。记录两组阻滞起效时间和维持时间；比较臂丛阻滞效果及感觉阻滞成功率；记录副作用；评价综合满意度。结果同样浓度容量的局麻药，阻滞起效时间A组较B组短（P〈0．05）；维持时间两组间比较差异无统计学意义（P〉0．05）。桡神经、肌皮神经、腋神经、前臂内侧皮神经、正中神经感觉完全阻滞率A组为93．3%-100%，明显高于B组的60．0%-86．7%（ P〈0．05）；两组尺神经感觉完全阻滞率均为100%。两组均无副作用发生；综合满意度A组较B组高（ P〈0．05）。结论用神经刺激仪定位喙突下臂丛阻滞操作简便，阻滞起效时间短，阻滞成功率高，效果确切。

关键词：喙突臂丛神经阻滞上肢手术