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Statistical Channel Modeling for Indoor VLC Communications Based on Channel Measurements

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China Communications 2024年第1期21卷 131-147页

作者： Shuo liu Pan Tang Jianhua Zhang Yue Yin Yu Tong Baobao liu Guangyi liu liang Xia State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and TelecommunicationsBeijing 100876China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China China Mobile Research Institute Beijing 100053China

Visible light communication(VLC)has attracted much attention in the research of sixthgeneration(6G)***,channel modeling is the foundation for designing efficient and robust VLC *** this paper,we present extensive VLC channel measurement campaigns in indoor environments,i.e.,an office and a *** on the measured data,the large-scale fading characteristics and multipath-related characteristics,including omnidirectional optical path loss(OPL),K-factor,power angular spectrum(PAS),angle spread(AS),and clustering characteristics,are analyzed and modeled through a statistical *** on the extracted statistics of the above-mentioned channel characteristics,we propose a statistical spatial channel model(SSCM)capable of modeling multipath in the spatial ***,the simulated statistics of the proposed model are compared with the measured *** instance,in the office,the simulated path loss exponent(PLE)and the measured PLE are 1.96and 1.97,***,the simulated medians of AS and measured medians of AS are 25.94°and 24.84°,***,the fact that the simulated results fit well with measured results has demonstrated the accuracy of our SSCM.

关键词： channel characteristics channel measurement channel modeling 6G spatial lobe VLC

Distribution, bioaccumulation, trophic transfer and risk assessment of trace elements in fish from a typical shallow outflow lake basin, China

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 141-156页

作者： Miao He Guijian liu Xiaodan shi Lei Wu Qiang Chen CAS Key Laboratory of Crust-Mantle Materials and Environment School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Anhui Academy of Environmental Sciences Hefei 230022China School of Resources and Environmental Engineering Hefei University of TechnologyHefei 230009China

Fish are important food sources for humans,and the availability of appropriate amount of trace elements(TEs)plays a crucial role in fish ***,due to large volumes of sewage discharge,high levels of certain elements are present in aquatic environments,and these elements accumulate in fish and potentially affect human *** this study,the distribution and bioaccumulation capacity of trace elements in six dominant fish species from Chaohu Lake(China)were *** results showed that the bioaccumulation capacity of fish for Zn was greater than other *** the source of the TEs in the fish were explored along with the concentration of the TEs in the aquatic environment,which indicated that TEs in fish were mainly obtained through ingestion and indirectly affected by the industrial activities in the ***,stable carbon and nitrogen isotopes were used to classify the trophic levels and explore the biological magnification of TEs of the *** was found that Sb and Sr showed biomagnification with the increase of trophic level of *** on the above analyses,the environmental biogeochemical cycle model of TEs in the lake was distinguished and established,which can offer valuable insights for sustainable fishery management in the downstream Yangtze River Delta ecosystem.

关键词： Trophic level Bioaccumulation Risk assessment Trace elements

Correction of a CADASIL point mutation using adenine base editors in hiPsCsandbloodvessel organoids

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Journal of Genetics and Genomics 2024年第2期51卷 197-207页

作者： Jingwen Wang Lei Zhang Guanglan Wu Jinni Wu Xinyao Zhou Xiaolin Chen Yongxia Niu Yiren Jiao Qianyi liu Puping liang Guang shi Xueqing Wu Junjiu Huang MOE Key Laboratory of Gene Function and Regulation State Key Laboratory of BiocontrolSchool of Life SciencesSun Yat-sen UniversityGuangzhouGuangdong 510275China Key Laboratory of Reproductive Medicine of Guangdong Province The First Affiliated Hospital and School of Life SciencesSun Yat-sen UniversityGuangzhouGuangdong 510275China Center of Reproductive Medicine Children's Hospital of Shanxi and Women Health Center of ShanxiTaiyuanShanxi 030013China

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic small vessel disease caused by mutations in the NOTCH3 gene. However, the pathogenesis of CADASIL remains unclear, and patients have limited treatment options. Here, we use human induced pluripotent stem cells (hiPSCs) generated from the peripheral blood mononuclear cells of a patient with CADASIL carrying a heterozygous NOTCH3 mutation (c.1261C>T, p.R421C) to develop a disease model. The correction efficiency of different adenine base editors (ABEs) is tested using the HEK293T-NOTCH3 reporter cell line. ABEmax is selected based on its higher efficiency and minimization of predicted off-target effects. Vascular smooth muscle cells (VSMCs) differentiated from CADASIL hiPSCs show NOTCH3 deposition and abnormal actin cytoskeleton structure, and the abnormalities are recovered in corrected hiPSC-derived VSMCs. Furthermore, CADASIL blood vessel organoids generated for in vivo modeling show altered expression of genes related to disease phenotypes, including the downregulation of cell adhesion, extracellular matrix organization, and vessel development. The dual adeno-associated virus (AAV) split-ABEmax system is applied to the genome editing of vascular organoids with an average editing efficiency of 8.82%. Collectively, we present potential genetic therapeutic strategies for patients with CADASIL using blood vessel organoids and the dual AAV split-ABEmax system.

关键词： CADASIL Induced pluripotent stem cells Adenine base editors AAV Blood vessel Organoid

The interannual periodicity of precipitation and its links to the large-scale circulations over the Third Pole

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Journal of Geographical Sciences 2024年第8期34卷 1457-1471页

作者： liang Liqiao liu Qiang LI Jiuyi State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchCASBeijing 100101China State Key Laboratory of Water Environment Simulation School of EnvironmentBeijing Normal UniversityBeijing 100875China Key Laboratory for Water and Sediment Sciences Ministry of EducationSchool of EnvironmentBeijing Normal UniversityBeijing 100875China Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources ResearchCASBeijing 100101China

To understand the spatio-temporal variability of precipitation(P)in the Third Pole region(centered on the Tibetan Plateau-TP),it is necessary to quantify the interannual periodicity of P and its relationship with large-scale *** this study,Morlet wavelet transform was used to detect significant(p<0.05)periodic characteristics in P data from meteorological stations in four climate domains in the Third Pole,and to reveal the major large-scale circulations that triggered the variability of periodic P,in addition to bringing large amounts of water *** wavelet transform results were as follows.(1)Significant quasiperiodicity varied from 2 to 11 *** high-frequency variability mode(2 to 6 years quasi-periods)was universal,and the low-frequency variability mode(7 to 11 years quasi-periods)was rare,occurring mainly in the westerlies and Indian monsoon domains.(2)The majority of periods were base periods(53%),followed by two-base *** all stations in the Third Pole(95%)showed one or two periods.(3)Periodicity was widely detected in the majority of years(84%).(4)The power spectra of P in the four domains were dominated by statistically significant high-frequency oscillations(ie.,with short periodicity).(5)Large-scale circulations directly and indirectly influenced the periodic P variability in the different *** mode of P variability in the different domains was influenced by interactions between large-scale circulation features and not only by the dominant circulation and its control of water vapour *** results of this study will contribute to better understanding of the causal mechanisms associated with P variability,which is important for hydrological science and waterresourcemanagement.

关键词： precipitation interannual periodicity Morlet wavelet large-scale circulations Third Pole

Gas-propelled nanomotors alleviate colitis through the regulation of intestinal immunoenvironment-hematopexis-microbiota circuits

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2732-2747页

作者： Bo Xiao Yuqi liang Ga liu Lingshuang Wang Zhan Zhang Libin Qiu Haiting Xu Sean Carr Xiaoxiao shi Rui LReis Subhas CKundu Zhenghua Zhu Department of Gastroenterology the First Affiliated Hospital of Nanchang UniversityNanchang 330006China College of Sericulture Textileand Biomass SciencesSouthwest UniversityChongqing 400715China Department of Neurology School of MedicineEmory UniversityAtlantaGA 30322USA Atlanta Veterans Affairs Medical Center DecaturGA 30033USA Department of Surgery School of MedicineEmory UniversityAtlantaGA 30322USA Bs Research Group I3Bs—Research Institute on BiomaterialsBiodegradables and BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineAveParkBarcoGuimaraes 4805-017Portugal

The progression of ulcerative colitis(UC)is associated with immunologic derangement,intestinal hemorrhage,and microbiota *** traditional medications mainly focus on mitigating inflammation,it remains challenging to address multiple ***,a versatile gas-propelled nanomotor was constructed by mild fusion of post-ultrasonic CaO_(2) nanospheres with Cu_(2)O *** resulting CaO_(2)–Cu_(2)O possessed a desirable diameter(291.3 nm)and a uniform size *** could be efficiently internalized by colonic epithelial cells and macrophages,scavenge intracellular reactive oxygen/nitrogen species,and alleviate immune reactions by pro-polarizing macrophages to the anti-inflammatory M2 *** nanomotor was found to penetrate through the mucus barrier and accumulate in the colitis mucosa due to the driving force of the generated oxygen *** administration of CaO_(2)–Cu_(2)O could stanch the bleeding,repair the disrupted colonic epithelial layer,and reduce the inflammatory responses through its interaction with the genes relevant to blood coagulation,anti-oxidation,wound healing,and ***,it restored intestinal microbiota balance by elevating the proportions of beneficial bacteria(e.g.,Odoribacter and Bifidobacterium)and decreasing the abundances of harmful bacteria(e.g.,Prevotellaceae and Helicobacter).Our gas-driven CaO_(2)–Cu_(2)O offers a promising therapeutic platform for robust treatment of UC via the rectal route.

关键词： Nanomotor Anti-inflammation Blood coagulation Immune regulation Hematopexis Microbiota rebalance Ulcerative colitis Rectal administration

Method of fabricating artificial rock specimens based on extrusion free forming(EFF)3D printing

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1455-1466页

作者： Xiaomeng shi Tingbang Deng Sen Lin Chunjiang Zou Baoguo liu Key Laboratory for Urban Underground Engineering of the Ministry of Education Beijing Jiaotong UniversityBeijing100044China School of Civil Engineering Beijing Jiaotong UniversityBeijing100044China Department of Civil Engineering Monash UniversityMelbourne3800Australia

Three-dimensional(3D)printing technology has been widely used to create artificial rock samples in rock *** 3D printing can create complex fractures,the material still lacks sufficient similarity to natural *** free forming(EFF)is a 3D printing technique that uses clay as the printing material and cures the specimens through high-temperature *** this study,we attempted to use the EFF technology to fabricate artificial rock *** results show the physico-mechanical properties of the specimens are significantly affected by the sintering temperature,while the nozzle diameter and layer thickness also have a certain *** specimens are primarily composed of SiO_(2),with mineral compositions similar to that of natural *** density,uniaxial compressive strength(UCS),elastic modulus,and tensile strength of the printed specimens fall in the range of 1.65–2.54 g/cm3,16.46–50.49 MPa,2.17–13.35 GPa,and 0.82–17.18 MPa,*** is capable of simulating different types of rocks,especially mudstone,sandstone,limestone,and ***,the simulation of hard rocks with UCS exceeding 50 MPa still requires validation.

关键词： Artificial rock 3D printing Extrusion free forming(EFF) Similarity analysis Mechanical properties

The design and engineering strategies of metal tellurides for advanced metal-ion batteries

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Journal of Energy Chemistry 2024年第2期89卷 579-598,I0013页

作者： Wenmiao Zhao Xiaoyuan shi Bo liu Hiroshi Ueno Ting Deng Weitao Zheng Key Laboratory of Automobile Materials of MOE School of Materials Science and EngineeringJilin Provincial International Cooperation Key Laboratory of High-Efficiency Clean Energy MaterialsJilin UniversityChangchun 130012JilinChina Key Laboratory of Polyoxometalate Science of Ministry of Education Northeast Normal UniversityChangchun 130024JilinChina Key Laboratory of Preparation and Application of Environmental Friendly Materials(Jilin Normal University) Ministry of EducationChangchun 130103JilinChina Creative Interdisciplinary Research Division The Frontier Research Institute for Interdisciplinary Sciences(FRIS)Department of ChemistryGraduate School of ScienceTohoku UniversitySendai 980-8578Japan

Owning various crystal structures and high theoretical capacity,metal tellurides are emerging as promising electrode materials for high-performance metal-ion batteries(MBs).Since metal telluride-based MBs are quite new,fundamental issues raise regarding the energy storage mechanism and other aspects affecting electrochemical *** volume expansion,low intrinsic conductivity and slow ion diffusion kinetics jeopardize the performance of metal tellurides,so that rational design and engineering are crucial to circumvent these ***,this review provides an in-depth discussion of recent investigations and progresses of metal tellurides,beginning with a critical discussion on the energy storage mechanisms of metal tellurides in various *** the following,recent design and engineering strategies of metal tellurides,including morphology engineering,compositing,defect engineering and heterostructure construction,for high-performance MBs are *** primary focus is to present a comprehensive understanding of the structural evolution based on the mechanism and corresponding effects of dimension control,composition,electron configuration and structural complexity on the electrochemical *** closing,outlooks and prospects for future development of metal tellurides are *** work also highlights the promising directions of design and engineering strategies of metal tellurides with high performance and low cost.

关键词： Metal tellurides Metal-ion battery Energy storage mechanism Material design and engineering

Phylogenetic study on Scenedesmacae with the description of a new genus Coccoidesmus ***.(Chlorophyceae,Chlorophyta)and chloroplast genome analyses

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Journal of Oceanology and Limnology 2024年第4期42卷 1272-1285页

作者： Qinghua WANG Ying HOU Yanhui LI Ying shi Guoxiang liu College of Biological Sciences and Technology Taiyuan Normal UniversityJinzhong 030619China Shanxi Vocational University of Engineering Science and Technology Jinzhong 030619China Key Laboratory of Algal Biology Institute of HydrobiologyChinese Academy of SciencesWuhan 430072China

Members of the family Scenedesmaceae are some of the most common algal taxa in inland ecosystems,and they are widely distributed in freshwaters,aerial,and sub-aerial *** the continuous updating of methods,the classic morphological taxonomy of this family needs to be *** recent years,many genera of Scenedesmaceae have been established via the use of molecular *** phylogenetic relationships within Scenedesmaceae were analyzed using different molecular markers and morphological data,and the new freshwater genus Coccoidesmus Wang,Hou et liu *** *** new species in this genus were also *** analysis based on tufA genes revealed that the new genus formed an independent clade closely related to ***,these two genera are characterized by significant morphological differences in colony arrangement and cell *** chloroplast genome of the type species was assembled and annotated,and analyses of genome structure and sequences were *** genome data could help clarify the phylogenetic relationships within this family.

关键词： phylogenetic Scenedesmaceae Coccoidesmus morphology chloroplast genome

Wintertime Arctic Sea-Ice Decline Related to Multi-Year La Niña Events

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Advances in Atmospheric Sciences 2024年第9期41卷 1680-1690页

作者： Wenxiu ZHONG Qian shi Qinghua YANG Jiping liu Song YANG School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen UniversityGuangzhou 510275China

Arctic sea ice has undergone a significant decline in the Barents-Kara Sea(BKS)since the late *** studies have shown that the decrease in sea ice caused by increased poleward moisture transport is modulated by tropical sea temperature changes(mainly referring to La Niña events).The occurrence of multi-year La Niña(MYLA)events has increased significantly in recent decades,and their impact on Arctic sea ice needs to be further *** this study,we investigate the relationship between sea-ice variation and different atmospheric diagnostics during MYLA and other La Niña(OTLA)*** decline in BKS sea ice during MYLA winters is significantly stronger than that during OTLA *** is because MYLA events tend to be accompanied by a warm Arctic-cold continent pattern with a barotropic high pressure blocked over the Urals ***,more frequent northward atmospheric rivers intrude into the BKS,intensifying longwave radiation downward to the underlying surface and melting the BKS sea ***,in the early winter of OTLA years,a negative North Atlantic Oscillation presents in the high latitudes of the Northern Hemisphere,which obstructs the atmospheric rivers to the south of *** infer that such a different response of BKS sea-ice decline to different La Niña events is related to stratospheric *** the rapid climate changes in the past,more frequent MYLA events may account for the substantial Arctic sea-ice loss in recent decades.

关键词： Arctic sea ice multi-year ENSO Ural blocking atmospheric river Barents-Kara Sea