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Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

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World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： Bo-fan chen Li liu fang-Zhen Lin Hai-Min Zeng Hai-Qiang huang Chun-fang Zhang Cong-Cong liu Xiang chen Jie Peng Yun-fa Wang Zhi-Lin Wang Bin chen De-Le liu Yun liu Zheng-Zheng Li xin-xing Zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina Department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

Thickness-dependent highly sensitive photodetection behavior of lead-free all-inorganic CsSnBr_(3) nanoplates

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Rare Metals 2022年第5期41卷 1753-1760页

作者： Dong liu Yan-Xue Yin Feng-Jing liu cheng-cheng miao xin-ming Zhuang Zhi-Yong Pang ming-sheng Xu ming chen Zai-xing yang School of Physics State Key Laboratory of Crystal MaterialsSchool of MicroelectronicsShandong UniversityJinan 250100China

Non-layered two-dimensional(2D) lead-free all-inorganic perovskites nanoplates have recently attracted considerable attention in photodetectors;however, the indepth investigation of thickness on photodetection performance is still lacking. In this work, by constructing the famous metal-semiconductor-metal photodetectors, the photodetection behaviors of thickness-controlled CsSnBr;nanoplates are investigated systematically. Ni electrodes are adopted for ensuring the good ohmic contact behaviors of as-fabricated photodetectors. With the increase in thickness, the photodetection performances improve accordingly, such as photocurrent increases from 0.22 to 19.40 nA, responsivity increases from 72.9 to 4893.7 mA·W^(-1), rise/decay time decreases from 11/35 to 3/10 ms, respectively. Notability, the dark current also increases with the increase in thickness, making the further investigation on the reduction in dark current *** of the as-fabricated photodetectors are stable, suggesting the careful thickness selection in next-generation high-performance lead-free all-inorganic perovskites photodetectors.

关键词： Thickness Photodetection Lead-free all-inorganic perovskites Non-layered two-dimensional perovskites CsSnBr3 nanoplates

Altered Brain Regional Homogeneity Following Contralateral Acupuncture at Quchi (LI 11) and Zusanli (ST 36) in Ischemic Stroke Patients with Left Hemiplegia: An fMRI Study

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Chinese Journal of Integrative Medicine 2020年第1期26卷 20-25页

作者： chen Shu-qi CAI De-chun chen Ji-xin yang Han liu Lian-sheng Medical Imaging Department The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510405China Medical College of Acu・Moxi and Rehabilitation Guangzhou University of Chinese MedicineGuangzhou510006China Artemisinin Research Center Guangzhou University of Chinese Medicine510006China The Second Clinical College Guangzhou University of Chinese MedicineGuangzhou510006China

Objective: To study the effect of contralateral acupuncture(CAT) at acupoints of Quchi(LI 11) and Zusanli(ST 36) on the unaffected limbs of ischemic stroke patients with left hemiplegia based on regional homogeneity(ReHo) indices. Methods: Ten ischemic stroke patients with left hemiplegia received CAT on right side at LI 11 and ST 36. Functional magnetic resonance imaging(fMRI) was performed before and after acupuncture. A ReHo analytical method was used to compare brain responses of patients before and after CAT operated by REST software. Results: The stimulation at both LI 11 and ST 36 on the unaffected limbs produced significantly different neural activities. CAT elicited increased ReHo values at the right precentral gyrus and superior frontal gyrus, decreased ReHo value at right superior parietal lobule, left fusiform gyrus and left supplementary motor area. Conclusions: Acupuncture at one side could stimulate bilateral regions. CAT could evoke the gyrus which was possibly related to motor recovery from stroke. A promising indicator of neurobiological deficiencies could be represented by ReHo values in post-stroke patients.

关键词： contralateral acupuncture ischemic stroke functional magnetic resonance imaging regional homogeneity

Fractal model of spontaneous imbibition in low-permeability reservoirs coupled with heterogeneity of pore seepage channels and threshold pressure

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Petroleum Science 2024年第2期21卷 1002-1017页

作者： ming-sheng Zuo Hao chen Xi-Liang liu Hai-Peng liu Yi Wu xin-Yu Qi National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China College of Safety and Ocean Engineering China University of Petroleum(Beijing)Beijing102249China

Spontaneous imbibition(SI)is an important mechanism for enhancing oil recovery in low-permeability *** to the strong heterogeneity,and the non-Darcy flow,the construction of SI model for lowpermeability reservoirs is extremely ***,traditional SI models based on single or averaged capillary tortuosity ignore the influence of heterogeneity of pore seepage channels and the threshold pressure(TP)on ***,in this work,based on capillary model and fractal theory,a mathematical model of characterizing SI considering heterogeneity of pore seepage channels is *** this basis,the threshold pressure was introduced to determine the pore radius at which the wetted phase can displace *** proposed new SI model was verified by imbibition experimental *** study shows that for weakly heterogeneous cores with permeability of 0-1 m D,the traditional SI model can characterize the imbibition process relatively accurately,and the new imbibition model can increase the coefficient of determination by 1.05 ***,traditional model has serious deviations in predicting the imbibition recovery for cores with permeability of 10-50 m *** new SI model coupling with heterogeneity of pore seepage channels and threshold pressure effectively solves this problem,and the determination coefficient is increased from 0.344 to 0.922,which is increased by2.68 *** low-permeability reservoirs,the production of the oil in transitional pores(0.01-0.1μm)and mesopores(0.1-1μm)significantly affects the imbibition recovery,as the research shows that when the heterogeneity of pore seepage channels is ignored,the oil recovery in transitional pores and mesopores decreases by 7.54%and 4.26%,*** analysis shows that increasing interfacial tension,decreasing contact angle,oil-water viscosity ratio and threshold pressure will increase imbibition *** addition,there are critical values for the influence of these factors o

关键词： Spontaneous imbibition Low-permeability reservoir Fractal model Threshold pressure Capillary tube

Copper-catalyzed direct acyloxylation of C(sp^2)–H bonds with Benzoic acids

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Science China Chemistry 2015年第8期58卷 1302-1309页

作者： sheng Zhao fa-Jie chen Bin liu Bing-Feng Shi Department of Chemistry Zhejiang University

A copper-catalyzed acyloxylation of C(sp2)–H bond with sterically bulky benzoic acids was *** protocol is compatible with a broad range of functional groups and could proceed in gram scale,providing an efficient and ... 详细信息

关键词： copper C-H activation acyloxylation ester bidentate

Prediction of Critical Conditions for Dynamic Recrystallization in 316LN Austenitic Steel

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Journal of Iron and Steel Research International 2016年第3期23卷 238-243页

作者： xin-gang liu Li-ge ZHANG Rong-sheng QI Lei chen miao JIN Bao-feng GUO Key Laboratory of Advanced Forging & Stamping Technology and Science(Yanshan University) Ministry of Education of China Yanshan University Library Yanshan University National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan University

Hot compression experiments conducted on a Gleeble-3500thermo-mechanical simulator and metallographic observation tests were employed to study the critical conditions of dynamic recrystallization（DRX）of 316 LN austenitic stainless *** true stress-true strain curves of 316 LN were obtained at deformation temperatures ranging from 900℃to 1 200℃and strain rates ranging from 0.001s-1 to *** on the above tests,the critical conditions of DRX were determined and compared with those obtained from work-hardening theory and the Cingara-McQueen flow stress ***,the microstructure was observed to validate the calculated *** ratio of critical strain to peak strain（εc/εp）for 316 LN was determined,and the quantitative relationship between the critical strain and the deformation parameters of 316 LN was *** results demonstrated that the onset of DRX corresponds to the constant normalized strain hardening rate（Γ）,namely,the critical strain hardening rateΓcfor316LN is equal to 0.65.

关键词： 316LN austenitic stainless steel hot deformation dynamic recrystallization critical condition

Current Status of Objectification of Four Diagnostic Methods on Constitution Recognition of Chinese Medicine

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Chinese Journal of Integrative Medicine 2022年第12期28卷 1137-1146页

作者： LI Cong-cong YAN xin-sheng liu ming-hao TENG Gui-fa School of Information Science and Technology Hebei Agricultural UniversityBaodingHebei Province 071001China Hebei Key Laboratory of Agricultural Big Data BaodingHebei Province 071001China

Chinese medicine(CM)has thousands of years of experience in prevention of *** for CM,people's constitution is closely related to their health status,thus recognition of CM constitution is the fundamental and core contentof research on constitution *** development of technologies such as sensors,arificial intelligence and big data,objectification of the four diagnostic methods of CM has gradually matured,bringing changes in the mindset and innovations in technical means for recognition of CM *** paper presents a systematic review of the latest research trends in constitution recognition based on objectification of diagnostic methods in CM.

关键词： Chinese medicine constitution recognition four diagnostic methods objectification machine learning deep learning

Inheritance and Availability of High Grain Number Per Spike in Two Wheat Germplasm Lines

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Journal of Integrative Agriculture 2012年第9期11卷 1409-1416页

作者： chen Dan ZHANG Jin-peng WANG Jian-sheng yang xin-ming liu Wei-hua GAQ Ai-nong LI Xiu-quan LI Li-hui National Key facility for Crop Gene Resources and Genetic Improvement/Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China Hybrid Rapeseed Research Center of Shaanxi Province/Shaanxi Rapeseed Branch of National Oil Crops Genetic Improvement Center Dali 715105 P.R.China

Grain number per spike （GNPS） is a major factor in wheat yield breeding. The development of high GNPS germplasm is widely emphasized in wheat-yield breeding. This paper reported two high GNPS wheat germplasm lines, Pubing 3228 and Pubing 3504, which had a stable and wide adaptability to different ecological regions. By exploring a nested cross design with reciprocals using Pubing 3228 or Pubing 3504 as a common parent and investigating the GNPS phenotypes of F1 hybrids in 2007-2008 and F2 populations in 2008-2009 of different cross combinations, the narrow-sense GNPS heritability was up to 49.58 and 52.23%, respectively. Genetic model analysis predictions suggested that GNPS in Pubing 3228 and Pubing 3504 was mainly controlled by additive genetic effects. Correlation analysis results between GNPS and 1 000- kernel weight （TKW） of F2 populations showed that TKW was not influenced with the increase of GNPS. The good coordination among three yield components of spike number per plant （SNPP）, GNPS, and TKW in the F2 segregating population implied that selection of good candidate individuals in breeding programs would be relatively straightforward. Overall, our results indicated that Pubing 3228 and Pubing 3504 are two potential germplasm lines for yield improvement of GNPS in pedigree selection of wheat breeding.

关键词： wheat high grain number per spike inheritance yield breeding

A public Cloud-based China's Landslide Inventory Database(Cs LID): development, zone, and spatiotemporal analysis for significant historical events, 1949-2011

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Journal of Mountain Science 2016年第7期13卷 1275-1285页

作者： LI Wei-yue liu Chun HONG yang ZHANG xin-hua WAN Zhan-ming Manabendra SAHARIA SUN Wei-wei YAO Dong-jing chen Wen chen sheng yang Xiu-qin YUE Jing Institute of Urban Study Shanghai Normal University Center for Spatial Information Science and Sustainable Development Applications Tongji University College of Surveying and Geo-Informatics Tongji University School of Civil Engineering and Environmental Sciences University of Oklahoma Advanced Radar Research Center University of Oklahoma State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University College of Architectural Engineering Civil Engineering and Environment Ningbo University Department of Geography Shanghai Normal University Engineering Center of SHMEC for Space Information and GNSS East China Normal University Applied Hydrometeorological Research Institute Nanjing University of Information Science & Technology Department of Stomatology Shanghai Tenth People’s Hospital of Tongji University

Landslide inventory plays an important role in recording landslide events and showing their temporal-spatial distribution. This paper describes the development, visualization, and analysis of a China's Landslide Inventory Database(Cs LID) by utilizing Google's public cloud computing platform. Firstly, Cs LID(Landslide Inventory Database) compiles a total of 1221 historical landslide events spanning the years 1949-2011 from relevant data sources. Secondly, the Cs LID is further broken down into six zones for characterizing landslide cause-effect, spatiotemporal distribution, fatalities, and socioeconomic impacts based on the geological environment and terrain. The results show that among all the six zones, zone V, located in Qinba and Southwest Mountainous Area is the most active landslide hotspot with the highest landslide hazard in China. Additionally, the Google public cloud computing platform enables the Cs LID to be easily accessible, visually interactive, and with the capability of allowing new data input to dynamically augment the database. This work developed a cyber-landslide inventory and used it to analyze the landslide temporal-spatial distribution in China.

关键词： Landslide Inventory Zone Distribution Cloud computing