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New Results on Almost Periodic Solution of Shunting Inhibitory Cellular Neural Networks with Continuously Distributed Delays

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Journal of Electronic Science and Technology of China 2008年第1期6卷 70-74页

作者： Jing liu pei-yong Zhu School of Applied Mathematics Universityof Electronic S~i~n~~ and Technology of China Chcngdu 610054 China

In this paper,the existence,uniqueness and global attractivity are discussed on almost periodic solution of SICNNs（shunting inhibitory cellular neural networks）with continuously distributed *** using the fixed point theorem,differential inequality technique and Lyapunov functional method,giving the new ranges of parameters,several sufficient conditions are obtained to ensure the existence,uniqueness and global attractivity of almost periodic *** with the previous studies,our methods are more effective for almost periodic solution analysis of SICNNs with continuously distributed *** existing results have been improved and *** order to show the effectiveness of the obtained results,an example is given in this paper.

关键词： Almost periodic solution global attractivity shunting inhibitory cellular neural networks.

Global Exponential Stability of Almost Periodic Solution of Cellular Neural Networks with Time-Varying Delays

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Journal of Electronic Science and Technology of China 2007年第3期5卷 238-242页

作者： Jing liu pei-yong Zhu The authors are with School of Applied Mathematics University of Electronic Science and Technology of China （UESTC） Chengdu 610054 China

In this paper, global exponential stability of almost periodic solution of cellular neural networks with time-varing delays （CNNVDs） is considered. By using the methods of the topological degree theory and generalized Halanay inequality, a few new applicable criteria are established for the existence and global exponential stability of almost periodic solution. Some previous results are improved and extended in this letter and one example is given to illustrate the effectiveness of the new results.

关键词： Almost periodic solution cellular neural networks with time-varying delays (CNNVDs) global exponential stability topological degree theory.

Regeneration and identification of interspecific asymmetric somatic hybrids obtained by donor-recipient fusion in cotton

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Chinese Science Bulletin 2009年第15期54卷 3035-3044页

作者： FU LiLi YANG XiYan ZHANG XianLong WANG ZhiWei FENG ChangHui liu ChuanXiang JIANG pei-yong ZHANG JinLong National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Wuhan 430070 China

Asymmetric hybrids between Gossypium hirsutum (YZ-1) and G. davidsonii were obtained by donor-recipient fusion. YZ-1 was considered the recipient and was pretreated with iodoacetamide (IOA), while G. davidsonii was considered the donor and was irradiated with ultraviolet (UV) before fusion. YZ-1 protoplasts stopped growth when treated with 0.5 mmol/L IOA for 20 min, and G. davidsonii protoplasts stopped growth when irradiated with 38.7 J/cm2 UV for 30 s. Asymmetric somatic hybrids were obtained by electrofusion between the separately treated protoplasts of the 2 species. The regenerated plants were identified by morphological, cytological, and molecular analysis. Most regenerated plants derived from fused protoplasts displayed new morphology; some were intermediate between the two parents and a few displayed recipient-like morphology. Chromosome numbers in these somatic hybrids mostly ranged from 40 to 73. The hybridity was confirmed by random amplified polymorphic DNA and simple sequence repeat analysis. Organelle DNA inheritance of the YZ-1 and G. davidsonii somatic hybrid was investigated by cleaved amplified polymorphism sequence and chloroplast simple sequence repeat analysis, which indicated that recombination and rearrangements might have occurred in some regions of mitochondrial and chloroplastic DNA. This is the first report of completely asymmetric hybrid production via donor–recipient fusion between G. hirsutum and G. davidsonii, which is a novel case in hybrid production following the symmetric fusion and asymmetric fusion based on UV irradiation in cotton.

关键词：不对称体细胞杂交融合识别棉花种间再生

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专利法:一种博弈论视角下的合作机制

云南大学学报（社会科学版） 2009年第6期8卷 57-62,71页

作者：刘永沛上海交通大学上海200240

本文试图用博弈论的方法来探究专利法机制设计的合理性。作者以没有专利制度的假设为逻辑起点,通过构建发明人-投资人博弈模型,认为专利法是解决"囚徒困境"的有效机制。在一个有效运行的专利制度下,发明人会积极申请专利,而投资人也会... 详细信息

本文试图用博弈论的方法来探究专利法机制设计的合理性。作者以没有专利制度的假设为逻辑起点,通过构建发明人-投资人博弈模型,认为专利法是解决"囚徒困境"的有效机制。在一个有效运行的专利制度下,发明人会积极申请专利,而投资人也会积极投资于这些专利技术。专利法用排他权给发明人提供正向激励,用专利无效宣告程序给发明人提供反向激励;用完全准确披露的技术信息给投资人提供正向激励,用专利侵权责任给投资人提供反向激励。通过这种制度设计,就可以改变博弈的原初结构,让双方在一个良好的制度框架内进行合作,从而促进技术的进步和创新。

关键词：专利法博弈论信息披露合作机制

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乙型病毒性肝炎数学模型及其控制

东北大学学报（自然科学版） 2007年第3期28卷 308-311页

作者：杨光张庆灵刘佩勇东北大学理学院辽宁沈阳110004

针对乙型肝炎病毒的传播方式以及各种状态间的转化模式,建立由微分方程表达的乙型肝炎数学模型.分析表明,如果该模型有正平衡点,则疾病消除点不稳定,此时该传染病将会蔓延,因此应对疾病实施有效控制:在采取母婴阻断和新出生婴儿免疫控... 详细信息

针对乙型肝炎病毒的传播方式以及各种状态间的转化模式,建立由微分方程表达的乙型肝炎数学模型.分析表明,如果该模型有正平衡点,则疾病消除点不稳定,此时该传染病将会蔓延,因此应对疾病实施有效控制:在采取母婴阻断和新出生婴儿免疫控制方法的基础上,再对易感人群施加免疫控制.构造出一个Lyapunov函数,应用Lyapunov稳定性理论,证明了施加上述控制后,该传染病模型在疾病消除点全局渐近稳定,即乙肝病毒最终可以灭绝,并得出了乙肝病毒最终消除的免疫条件.

关键词：传染性疾病乙型肝炎病毒免疫控制数学模型全局渐近稳定

RGS4 promotes the progression of gastric cancer through the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition

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World Journal of Gastroenterology 2025年第2期31卷 113-127页

作者： Peng-Yu Chen pei-Yao Wang Bang liu Yang-Pu Jia Zhao-Xiong Zhang Xin liu Dao-Han Wang yong-Jia Yan Wei-Hua Fu Feng Zhu Department of General Surgery Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Department of General Surgery Jincheng People’s HospitalJincheng 048000Shanxi ProvinceChina

BACKGROUND Regulator of G protein signaling(RGS)proteins participate in tumor formation and metastasis by acting on theα-subunit of heterotrimeric G *** speci-fic effect of RGS,particularly RGS4,on the progression of gastric cancer(GC)is not yet *** To explore the role and underlying mechanisms of action of RGS4 in GC *** The prognostic significance of RGS4 in GC was analyzed using bioinformatics based public databases and verified by immunohistochemistry and quantitative polymerase chain reaction in 90 patients with *** assays were employed to assess the carcinogenic impact of RGS4,and the mechanism of its possible influence was detected by western blot analysis.A nude mouse xenograft model was established to study the effects of RGS4 on GC growth in *** RGS4 was highly expressed in GC tissues compared with matched adjacent normal *** RGS4 expression was correlated with increased tumor-node-metastasis stage,increased tumor grade as well as poorer overall survival in patients with *** experiments demonstrated that RGS4 knockdown suppressed GC cell proliferation,migration and ***,xenograft experiments confirmed that RGS4 silencing significantly inhibited tumor ***,RGS4 knockdown resulted in reduced phosphorylation levels of focal adhesion kinase,phosphatidyl-inositol-3-kinase,and protein kinase B,decreased vimentin and N-cadherin,and elevated *** High RGS4 expression in GC indicates a worse prognosis and RGS4 is a prognostic ***4 influences tumor progression via the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition.

关键词： Gastric cancer Prognosis Regulator of G protein signaling 4 Focal adhesion kinase Epithelial-mesenchymal transition

Network pharmacology:Changes the treatment mode of"one disease-one target"in cancer treatment

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 268-271页

作者： Shuai liu yong-Wei Yu Department of Cardiology The First People’s Hospital of JiashanJiaxing 314100Zhejiang ProvinceChina Department of Critical Care Medicine The First Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

The article concluded that network pharmacology provides new ideas and insights into the molecular mechanism of traditional Chinese medicine(TCM)treatment of *** is a new choice and hot spot in the field of cancer *** have also previously published studies on TCM and network *** this letter,we summarize the new paradigm of network pharmacology in cancer treatment mechanisms.

关键词： Network pharmacology Cancer Multicomponent Multitarget Therapy

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T-S离散模糊系统的二次稳定性

东北大学学报（自然科学版） 2006年第10期27卷 1063-1066页

作者：杨晓光张庆灵刘晓东刘佩勇东北大学理学院辽宁沈阳110004 大连海事大学数学系辽宁大连116026

研究了T-S离散模糊系统的二次稳定性,目的是得到更简单的稳定性条件·首先,引入适合于T-S离散模糊系统的Lyapunov函数,得到了该系统稳定的充分条件·然后利用Schur补将非线性矩阵不等式问题转换成线性矩阵不等式问题,从而把被研究系统... 详细信息

研究了T-S离散模糊系统的二次稳定性,目的是得到更简单的稳定性条件·首先,引入适合于T-S离散模糊系统的Lyapunov函数,得到了该系统稳定的充分条件·然后利用Schur补将非线性矩阵不等式问题转换成线性矩阵不等式问题,从而把被研究系统转化为凸组合系统,提出了基于LMI的更为简单的二次稳定性的充分条件·最后,给出了一个计算例子,计算结果说明可以使用LMI和MATLAB求解这类问题,同时证明了上述方法的优越性·利用该方法可以进一步研究T-S离散模糊系统的鲁棒控制、H∞控制等问题·

关键词： T-S离散模糊系统 Schur补二次稳定性线性矩阵不等式正定矩阵充分条件

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一类不确定广义时滞系统的鲁棒耗散控制

控制理论与应用 2007年第6期24卷 1038-1042页

作者：杨丽张庆灵杨晓光刘佩勇辽宁大学数学系辽宁沈阳110036 东北大学系统科学研究所辽宁沈阳110004

将耗散不确定性引入到不确定广义系统中,在状态空间下,通过线性矩阵不等式(LMI)的方法,研究了一类不确定广义时滞系统的鲁棒耗散控制问题.给出了此类不确定广义系统严格耗散的充分条件,然后设计了此类不确定广义系统的鲁棒耗散控制器,... 详细信息

将耗散不确定性引入到不确定广义系统中,在状态空间下,通过线性矩阵不等式(LMI)的方法,研究了一类不确定广义时滞系统的鲁棒耗散控制问题.给出了此类不确定广义系统严格耗散的充分条件,然后设计了此类不确定广义系统的鲁棒耗散控制器,最后通过数值算例验证了定理的可行性.

关键词：耗散不确定性鲁棒稳定耗散控制器