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Effectiveness and safety of acupuncture in treatment of pregnancyrelated symptoms:a systematic review and Meta-analysis

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Journal of Traditional Chinese Medicine 2024年第1期44卷 16-26页

作者： liu Tingting liu Tongou liu mingfu School of Traditional Chinese Medicine Clinical Medicine Hubei University of Traditional Chinese MedicineWuhan 430000China First Clinical College of Hubei University of Traditional Chinese Medicine Wuhan 430000China Department of Acupuncture and Tuina Affiliated Hospital of Hubei University of Traditional Chinese MedicineHubei Provincial Hospital of Traditional Chinese MedicineWuhan 430000China

OBJECTIVE:To systematically evaluate the efficacy and safety of acupuncture(AM)in the treatment of pregnancyrelated symptoms such as acute vomiting during pregnancy.METHODS:We comprehensively searched the available literature up to November 2021,including Pub Med,Embase,Cochrane Library,Chinese Biomedical Literature Database,and China National Knowledge Infrastructure Database,for randomized controlled trials(RCTs)on AM for the treatment of severe vomiting,insomnia,pharyngeal and pelvic pain,mood abnormalities,and dyspepsia during pregnancy.RESULTS:Sixteen RCTs with a cumulative sample size of 1178 cases were included.Of these,964 patients were included in the Meta-analysis.The Meta-analysis results showed that AM was more efficient than Western medicine in treating discomfort during pregnancy[odds ratio(OR)=1.19,95%confidence interval(CI)(1.11,1.28),P<0.01].AM was better than the control group in improving the visual analog scale scores[standard mean difference(SMD)=0.62,95%CI(0.53,0.71),P<0.01].AM was superior to the control group in improving Numerical Rating Scale(NRS)symptom scores[OR=7.31,95%CI(3.36,15.94),P<0.01].There was no significant difference in adverse effects between the AM and sham-AM groups and the analgesic drug group[OR=0.70,95%CI(0.39,1.28),P=0.25],but the treatment and control groups had mild adverse effects with a low incidence.CONCLUSIONS:AM is more effective than other treatments or pharmacotherapy alone in the treatment of pregnancy-related symptoms,and is relatively safe.However,the quality of the included trials was rather poor,and high-quality studies are required to confirm our findings.

关键词： acupuncture pregnancy nausea vomiting sleep initiation and maintenance disorders low back pain pelvic pain mood abnormalities Meta-analysis systematic review

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超燃冲压发动机研究回顾与展望

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航空学报 2024年第5期45卷 218-244页

作者：刘小勇王明福刘建文任鑫张轩北京动力机械研究所北京100074

自20世纪50年代以来,航空航天领域把超燃冲压发动机作为高超声速推进系统的一种追求目标,在理论和技术方面矢志不渝地开展了大量研究工作。21世纪初,美国取得了一系列接近实际应用的技术突破,将超燃冲压发动机技术的研究和应用推动至新... 详细信息

自20世纪50年代以来,航空航天领域把超燃冲压发动机作为高超声速推进系统的一种追求目标,在理论和技术方面矢志不渝地开展了大量研究工作。21世纪初,美国取得了一系列接近实际应用的技术突破,将超燃冲压发动机技术的研究和应用推动至新阶段。简述了超燃冲压发动机工作原理,论述了双模态工作过程、高超声速压缩流动、超声速燃烧、超高温结构与热防护、地面试验与数值模拟等关键技术的难点和新进展,并针对超燃冲压发动机宽速域、可重复和更高马赫数等当前重点技术发展方向,阐述了认识和建议。

关键词：超燃冲压发动机超声速燃烧超高温结构再生冷却高超声速

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Comparison of transport coefficients before and after density pump-out induced by resonant magnetic perturbation using a BOUT++ six-field model on the EAST tokamak

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Plasma Science and Technology 2024年第6期26卷 111-119页

作者：邓成成刘子奚夏天阳刘彦君厉鹏程龙飞飞高翔王守信李国强刘海庆臧庆李玖瑛杨康宁吴茗甫尹晓宇李弘谢锦林兰涛毛文哲刘阿娣周楚丁卫星庄革刘万东 the EAST Team Department of Plasma Physics and Fusion Engineering University of Science and Technology of ChinaHefei 230026People’s Republic of China Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People’s Republic of China

Many experiments have demonstrated that resonant magnetic perturbation(RMP) can affect the turbulent transport at the edge of the tokamak. Through the Experimental Advanced Superconducting Tokamak(EAST) density modulation experiment, the particle transport coefficients were calculated using the experimental data, and the result shows that the particle transport coefficients increase with RMP. In this study, the six-field two-fluid model in BOUT++ is used to simulate the transport before and after density pump-out induced by RMP,respectively referred as the case without RMP and the case with RMP. In the linear simulations,the instabilities generally decreases for cases with RMP. In the nonlinear simulation, ELM only appears in the case without RMP. Additionally, the particle transport coefficient was analyzed,and the result shows that the particle transport coefficient becomes larger for the case with RMP,which is consistent with the experimental conclusion. Moreover, its magnitude is comparable to the results calculated from experimental data.

关键词： BOUT++ resonant magnetic perturbation(RMP) transport coefficients

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基于深度学习的人体行为识别综述

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现代信息科技 2024年第4期8卷 50-55页

作者：吴婷刘瑞欣刘明甫刘海华中南民族大学湖北武汉430074

近年来,人体行为识别是计算机视觉领域的研究热点,在诸多领域有着广泛的应用,例如视频监控、人机交互等。随着深度学习的发展,卷积神经网络作为其领域中表现能力优越的人工神经网络之一,在动作识别领域中发挥着不可或缺的作用。文章基... 详细信息

近年来,人体行为识别是计算机视觉领域的研究热点,在诸多领域有着广泛的应用,例如视频监控、人机交互等。随着深度学习的发展,卷积神经网络作为其领域中表现能力优越的人工神经网络之一,在动作识别领域中发挥着不可或缺的作用。文章基于深度学习总结基于2D CNN和基于3D CNN的动作识别方法,根据不同算法搭建的模型进行性能对比,同时对基准数据集进行归纳总结。最后探讨了未来人体动作识别的研究重难点。

关键词：动作识别深度学习卷积神经网络图像分类

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Photo-induced visual response of western flower thrips attracted and repulsed by their phobotaxis spectrum light

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International Journal of Agricultural and Biological Engineering 2022年第27期15卷 48-57页

作者： Qihang liu Yuqing Wu mingfu Zhao Henan Institute of Science and Technology Xinxiang 453003HenanChina Institute of Plant Protection Henan Academy of Agricultural SciencesZhengzhou 450002China

This study aimed to clarify the synergistic phototactic attraction-repulsion effect formed by the photo-induced approach-avoidance behavior of thrips,construct phototactic attraction-repulsion light control technologies.The phototactic push-pull effects of red light and UV(365 nm),violet(405 nm),green(520 nm),and yellow(560 nm)single light,as well as their pairwise combined light on the behavior of western flower thrips were investigated using an apparatus that measured thrips response.The study also analyzed the influence of light properties on the phototactic attraction-repulsion effects of thrips and the synergistic effects of red light,and the attraction-repulsion regulation mode.The influence factors on the photo-induced attraction-repulsion effect of thrips were also discussed.The results showed that the red light,presenting the push effect,drove thrips to respond to the sensitive light.The synergistic attraction-repulsion effect of red light and singlelight,as well as that of red light and combined light was related to the light intensity.However,the attraction-repulsion synergism did not reflect thrips response effect and approach effect pulled and pushed by red light and single light,red light and combined light.Thrips preference for green-yellow light,and their behavior depended on the degree of UV light,making the attraction-repulsion synergy of red and green light the strongest.When the light intensity increased,the attraction-repulsion synergy of red and yellow light was the strongest.The attraction-repulsion response to red light and single light was related to the spectral attribute of the single light,with that of red lightand UV light being better.The attraction-repulsion response to red light and combined light was related to light intensity.The intensity of combined light made the attraction-repulsion response to red light and the combined UV and violet light be the best,and the brightness of long-short spectrum light rendered red light and the combined UV and yellow light the best.All such lig

关键词： Western flower thrips photo-induced visual response effect attraction-repulsion effect phobotaxis spectrum light light intensity

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Synergistic influence of the capture effect of western flower thrips(Frankliniella occidentalis)induced by proportional yellow-green light in the greenhouse

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International Journal of Agricultural and Biological Engineering 2023年第1期16卷 88-94页

作者： Qihang liu Xinfa Wang mingfu Zhao Tao liu Henan Institute of Science and Technology Xinxiang 453003HenanChina Inner Mongolia Agricultural University Huhehot 010018China

To clarify the influence of yellow,green,and proportional yellow-green light on the capture effect,western flower thrips,Frankliniella occidentalis(Pergande),were captured using different self-made light sources in a greenhouse.The bio-activity capture effect of thrips was regulated by light and analyzed to determine the reasons for the changes in their capture by light.The results showed that the thrips’capture effect induced by different light sources with the same brightness was positively correlated with night temperature.When the average night temperature was 27℃(19:00-21:30),the capture effect was optimal,indicating that the coupling effect of light temperature can regulate the capture effect of thrips.Green light intensified and yellow light inhibited the visual trend sensitivity of thrips to yellow-green light of differing proportions.The capture effect trapped by a green-yellow light ratio of 4:1 was optimal(1088.00 individuals in night time),while that of yellow light was the worst(456.67 individuals/night),thus,indicating that visual trend sensitivity of thrips to green light was higher than that of yellow light.Such differences originated from the differences in the photoelectric thermal conversion effect of spectral optical properties,and the spectral photo-thermal effect was the main reason that thrips produced a light-trapped behavior.Night light enhanced the sensitivity of thrips’responses to a white adhesive board during the daytime,and the effect of yellow light intensity was the strongest(1563.00 individuals in the daytime),while that of green light was the weakest(75.33 individuals in the day time).Additionally,yellow light intensified while green light inhibited the regulatory effect of different proportions of yellow-green light on the bio-activity of thrips.However,the capture effect of day and night corresponding to 4:1 green-yellow light was the best(2019.67 individuals in day and night).The function of the photo-thermal effect on the capture effect of thrips was affected by the decrease

关键词： western flower thrips proportional yellow-green light synergistic influence effect capture effect

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RRT Autonomous Detection Algorithm Based on Multiple Pilot Point Bias Strategy and Karto SLAM Algorithm

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Computers, Materials & Continua 2024年第2期78卷 2111-2136页

作者： Lieping Zhang Xiaoxu Shi liu Tang Yilin Wang Jiansheng Peng Jianchu Zou Key Laboratory of Advanced Manufacturing and Automation Technology(Guilin University of Technology) Education Department of Guangxi Zhuang Autonomous RegionGuilin541006China College of Mechanical and Control Engineering Guilin University of TechnologyGuilin541006China Guilin mingfu Robot Technology Company Limited Guilin541199China Key Laboratory of AI and Information Processing(Hechi University) Education Department of Guangxi Zhuang Autonomous RegionYizhou546300China

A Rapid-exploration Random Tree(RRT)autonomous detection algorithm based on the multi-guide-node deflection strategy and Karto Simultaneous Localization and Mapping(SLAM)algorithm was proposed to solve the problems of low efficiency of detecting frontier boundary points and drift distortion in the process of map building in the traditional RRT algorithm in the autonomous detection strategy of mobile robot.Firstly,an RRT global frontier boundary point detection algorithm based on the multi-guide-node deflection strategy was put forward,which introduces the reference value of guide nodes’deflection probability into the random sampling function so that the global search tree can detect frontier boundary points towards the guide nodes according to random probability.After that,a new autonomous detection algorithm for mobile robots was proposed by combining the graph optimization-based Karto SLAM algorithm with the previously improved RRT algorithm.The algorithm simulation platform based on the Gazebo platform was built.The simulation results show that compared with the traditional RRT algorithm,the proposed RRT autonomous detection algorithm can effectively reduce the time of autonomous detection,plan the length of detection trajectory under the condition of high average detection coverage,and complete the task of autonomous detection mapping more efficiently.Finally,with the help of the ROS-based mobile robot experimental platform,the performance of the proposed algorithm was verified in the real environment of different obstacles.The experimental results show that in the actual environment of simple and complex obstacles,the proposed RRT autonomous detection algorithm was superior to the traditional RRT autonomous detection algorithm in the time of detection,length of detection trajectory,and average coverage,thus improving the efficiency and accuracy of autonomous detection.

关键词： Autonomous detection RRT algorithm mobile robot ROS Karto SLAM algorithm

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Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis

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Journal of Clinical and Translational Hepatology 2023年第5期11卷 1069-1078页

作者： Lu Zhang mingfu Wang Ran An Jun Dai Shujun liu Ming Chen Haoran Ding Department of Hepatobiliary Surgery Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjingJiangsuChina Surgery Department I Zhangjiagang Traditional Chinese Medicine HospitalSuzhouJiangsuChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Wannan Medical CollegeWuhuAnhuiChina Department of Hepatobiliary Surgery Nanjing Drum Tower HospitalClinical College of Traditional Chinese and Western MedicineSchool of PharmacyNanjing University of Chinese MedicineNanjingJiangsuChina

Background and Aims:Donors with fatty livers are considered to address the shortage of livers for transplantation,but those livers are particularly sensitive to ischemia-reperfusion injury(IRI),and an increased incidence of graft failure is observed.Kupffer cells account for 20–35%of liver nonparenchymal cells,and have been shown to participate in the process of IRI and inflammatory reactions of hepatic steatosis.NOD-like receptor thermal protein domain-associated protein 3(NLRP3)is an intracellular sensor activated by Kupffer cells to promote generation and participates in IRI.Dynamics-associated protein 1(Drp1)is one of the main proteins regulating mitochondrial division and exacerbates IRI by affecting mitochondrial dynamics.The mechanism of interaction of Kupffer cells with Drp1 and NLRP3 to aggravate IRI has not been clarified.Methods:A mouse model of hepatic steatosis was established by feeding the mice with a high-fat diet.In vitro experiments were performed using AML12 normal mouse liver cells and RAW264.7 mononuclear macrophage cells cultured in medium with palmitate and oleic acid.Western blotting and immunohistochemical(IHC)staining were used to detect the expression of NLRPP3 and Drp1 in IRI in the control and high-fat diet groups.The expression of F4/80+cells during IRI in hepatic steatosis was verified by IHC staining,and the role of NLRPP3 and Drp1 in Kupffer-cell mediated IRI was investigated by targeting Drp-1 inhibition.Results:Drp1 and NLRP3 expression was increased during IRI in hepatic steatosis,and the expression of Drp1 and NLRP3 were decreased after the elimination of Kupffer cells.That indicated Kupffer cells were involved in the process of IRI in hepatic steatosis through the action of Drp1 and NLRP3.After Drp1 inhibition,liver function was restored and NLRP3 expression level was reduced.Conclusions:Kupffer cells aggravated IRI in hepatic steatosis via NLRP3 and Drp1.Drp1 inhibitors might be useful as specific therapeutics to alleviate IRI in hepatic steatosis and may have promise in cas

关键词： Drp1 Kupffer cells NLRP3 Hepatic steatosis Ischemia-reperfusion

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酶解鲍鱼肽特性及其抗氧化与调节免疫的研究

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食品与发酵工业 2024年第9期50卷 23-28页

作者：江新辉江敏谢永灿张国强蓝登杭刘海霞温海兰江铭福福建大众健康生物科技有限公司福建福州350500 福州日兴水产食品有限公司福建福州350500 江南大学未来食品科学中心江苏无锡214122

该研究旨在探究酶解鲍鱼肽的分子特性及其抗氧化、调节免疫的功能。通过酶解获得鲍鱼多肽,利用液相色谱、氨基酸分析仪分别测定了鲍鱼肽分子质量和氨基酸含量,并在小鼠体内研究了鲍鱼肽抗氧化和调节免疫的功能,均设置低(0.25 g/kg BW)、... 详细信息

该研究旨在探究酶解鲍鱼肽的分子特性及其抗氧化、调节免疫的功能。通过酶解获得鲍鱼多肽,利用液相色谱、氨基酸分析仪分别测定了鲍鱼肽分子质量和氨基酸含量,并在小鼠体内研究了鲍鱼肽抗氧化和调节免疫的功能,均设置低(0.25 g/kg BW)、中(0.5 g/kg BW)、高(1.0 g/kg BW)3个剂量组,以及对应的对照组。研究结果显示鲍鱼肽的分子质量低于6500 Da占95%,氨基酸含量为72.54%。体内实验结果显示,抗氧化实验中,3个剂量组小鼠血清中的丙二醛和蛋白质羰基含量显著低于模型组,超氧化歧化酶和还原性谷胱甘肽含量显著高于模型组。在调节免疫实验中,与模型组相比,中、高剂量组小鼠白细胞数显著高于模型组,各组细胞免疫功能均无显著差异,体液免疫中,高剂量组小鼠脾细胞中半数溶血值和溶血空斑数量均显著提高,且中、高剂量组的NK细胞活性显著提高。综上所述,鲍鱼肽的分子质量小且氨基酸含量高,具有抗氧化和调节免疫的功能。

关键词：鲍鱼肽酶解氨基酸抗氧化调节免疫力

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Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17^(+) γδ T cells

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第4期24卷 312-325页

作者： Pan liu mingfu liu Deshuang XI Yiguang BAI Ruixin MA Yaomin MO Gaofeng ZENG Shaohui ZONG Department of Spine Osteopathic the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Department of Orthopaedics the Third Affiliated Hospital of Xinxiang Medical UniversityXinxiang 453000China Department of Orthopaedics Nanchong Central Hosipitalthe Second Clinical Institute of North Sichuan Medical CollegeNanchong 637000China Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry Guangxi Medical UniversityNanning 530021China College of Public Hygiene of Guangxi Medical University Nanning 530021China

Spinal cord injury(SCI)causes motor,sensory,and autonomic dysfunctions.The gut microbiome has an important role in SCI,while short-chain fatty acids(SCFAs)are one of the main bioactive mediators of microbiota.In the present study,we explored the effects of oral administration of exogenous SCFAs on the recovery of locomotor function and tissue repair in SCI.Allen’s method was utilized to establish an SCI model in Sprague-Dawley(SD)rats.The animals received water containing a mixture of 150 mmol/L SCFAs after SCI.After 21 d of treatment,the Basso,Beattie,and Bresnahan(BBB)score increased,the regularity index improved,and the base of support(BOS)value declined.Spinal cord tissue inflammatory infiltration was alleviated,the spinal cord necrosis cavity was reduced,and the numbers of motor neurons and Nissl bodies were elevated.Enzyme-linked immunosorbent assay(ELISA),real-time quantitative polymerase chain reaction(qPCR),and immunohistochemistry assay revealed that the expression of interleukin(IL)-10 increased and that of IL-17 decreased in the spinal cord.SCFAs promoted gut homeostasis,induced intestinal T cells to shift toward an anti-inflammatory phenotype,and promoted regulatory T(Treg)cells to secrete IL-10,affecting Treg cells and IL-17^(+)γδT cells in the spinal cord.Furthermore,we observed that Treg cells migrated from the gut to the spinal cord region after SCI.The above findings confirm that SCFAs can regulate Treg cells in the gut and affect the balance of Treg and IL-17^(+)γδT cells in the spinal cord,which inhibits the inflammatory response and promotes the motor function in SCI rats.Our findings suggest that there is a relationship among gut,spinal cord,and immune cells,and the“gut-spinal cord-immune”axis may be one of the mechanisms regulating neural repair after SCI.

关键词： Short-chain fatty acids(SCFAs) Spinal cord injury(SCI) Regulatory T cells IL-17^(+)γδT cells Neuroprotection Inflammation Motor function recovery

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