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Evaluation of selenium and carotenoid concentrations of 200 foxtail millet accessions from China and their correlations with agronomic performance

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Journal of Integrative Agriculture 2016年第7期15卷 1449-1457页

作者： liu min-xuan ZHANG Zong-wen REN Gui-xing ZHANG Qi WANG Yin-yue LU Ping Institute of Crop Science Chinese Academy of Agricultural Sciences Faculty of Life Science Jilin Agricultural University

As selenium and carotenoids are essential micronutrients, the determination of their concentrations in different varieties is important in the breeding of foxtail milet （Setaria italicaL. ***.）. To identify selenium- and carotenoid-enriched foxtail milet varieties and to analyze correlations between trace elements and agronomic traits, we measured the selenium and carotenoid concentrations of 200 Chinese accessions by high-performance liquid chromatography and atomic lfuorescence spectrometry. Our analysis revealed that lutein concentration in 200 foxtail milet accessions folowed normal distribution and average was 3.1 μg g–1. The mean value of zeaxanthin concentration in 200 accessions was 8.6 μg g–1. Lutein and zeaxanthin concentrations were higher in the foxtail milet from Liaoning than in varieties from other locations, with averages of 10.0 and 3.5 μg g–1, respectively. The average measured selenium concentration was 100.3 μg kg–1. The highest average selenium concentration, 110.3 μg kg–1, was found in varieties from Shanxi. Varieties from Inner Mongolia had the lowest average selenium concentration, 84.7 μg kg–1, which was signiifcantly lower （P〈0.05） than that of Shanxi. Selenium con-centrations of 23 varieties were higher than 117.9 μg kg–1, accounting for 11.5% of the total, thereby were considered to be enriched in selenium. In addition, we identiifed 29 lutein-enriched varieties （〉4.27 μg g–1） and 30 zeaxanthin-enriched ones （〉12.63 μg g–1）, which corresponded to 14.5 and 15% of tested accessions, respectively. Correlation analysis revealed that selenium concentration was signiifcantly positively correlated with spikelet length （P〈0.01）, while zeaxanthin concentration was signiifcantly correlated with grass weight （P〈0.05） and spikelet length （P〈0.01）. No correlation was found between lutein concentration and agronomic characters, selenium content or zeaxanthin content. Our results should contribute substantialy to the selection of suitable varieties

关键词： foxtail milet varieties selenium carotenoids HPLC correlation analysis

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ERPS OF CHARACTERS OF CHINESE WORDS COMPARED WITH TONE AND PICTURE STIMULI IN HUMAN YOUNG AND AGED SUBJECTS

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神经解剖学杂志 2001年第B7期17卷 78-80页

作者： Feng-Jun liu, Xun WU, min-xuan YU Department of Neurology, The First Hospital, Peking University, Beijing, 100034

Event related-potentials (ERPs) are divided into exogenous and endogenous components. The exogenous components include P1, N1 and P2 waves, and the endogenous include N2 and P3 waves. The endogenous components are sensitive to psychological variables. There were a few of reports about ERPs of Characters of Chinese Words (CWW). We studied the ERPs and reaction time (RT) elicited by stimulation with CCW on adolescents and aged persons, and compared them with ERPs to tone and picture stimuli.

关键词：年轻人老年人汉字笔划语音刺激图形刺激事件相关电位 ERPS

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胰岛素样因子、睾酮及骨代谢指标预测老年男性骨质疏松性骨折的意义

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中国组织工程研究 2015年第24期19卷 3778-3782页

作者：刘宣民博兴县人民医院外二科山东省滨州市256500

背景:老年男性骨质疏松的发病率随着国内人口老龄化趋势的加剧逐年提升,骨质疏松患者容易发生骨折,对患者的生命安全造成严重威胁,但目前临床上仍缺少有效的筛选措施预防骨质疏松的发生。目的:探究胰岛素样因子、睾酮及骨代谢指标水平... 详细信息

背景:老年男性骨质疏松的发病率随着国内人口老龄化趋势的加剧逐年提升,骨质疏松患者容易发生骨折,对患者的生命安全造成严重威胁,但目前临床上仍缺少有效的筛选措施预防骨质疏松的发生。目的:探究胰岛素样因子、睾酮及骨代谢指标水平在预测老年男性骨质疏松性骨折中的临床意义。方法:选取骨质疏松症男性患者120例作为观察组,另选择同时期收治的非骨质疏松症体检健康的男性人群120例作为对照组,两组受试者在年龄及体质量指数等方面比较差异无显著性意义,具有可比性。对两组受试者抽血检测胰岛素样因子、血清睾酮及骨代谢指标的水平。结果与结论:观察组患者腰椎侧位骨密度和左股骨颈骨密度均显著低于对照组(P0.05)。结果提示,通过检测老年男性血清中睾酮、胰岛素样因子及部分骨代谢指标的水平,可早期预测骨密度,为筛查老年男性骨质疏松症的高危状态起到一定的预测作用,具有一定的参考价值。

关键词：组织构建骨组织工程骨密度睾酮骨代谢指标老年男性睾酮性骨折

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Three-dimensional fracture of UO2 ceramic pellets by phase field modeling

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 169-180页

作者： Wei Xiong xuan Ye Hongzhang Cheng Xiaoming liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education Tsinghua University State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences

Fracture is the primary failure type for the UO2ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional （3D） UO2ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

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长江朱沱断面磷浓度与通量变化及来源解析

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环境科学 2024年第1期45卷 159-172页

作者：娄保锋谢卫民黄波刘旻璇生态环境部长江流域生态环境监督管理局监测与科研中心武汉430010

磷(P)是长江流域备受关注的污染物.金沙江下游向家坝水库和溪洛渡水库分别于2012年和2013年蓄水成库,极大改变了库区及长江宜宾至江津段(金沙江、岷江和长江“三江口”与三峡水库之间)水沙条件和磷的赋存及输移规律.朱沱断面是宜宾至江... 详细信息

磷(P)是长江流域备受关注的污染物.金沙江下游向家坝水库和溪洛渡水库分别于2012年和2013年蓄水成库,极大改变了库区及长江宜宾至江津段(金沙江、岷江和长江“三江口”与三峡水库之间)水沙条件和磷的赋存及输移规律.朱沱断面是宜宾至江津段代表断面,既可以反映金沙江梯级水库及岷沱江水环境变化等所产生的综合效应,又是三峡水库的入库断面.研究了2002~2019年长江朱沱断面径流量、悬浮泥沙(SS)浓度与输沙量、磷浓度与通量[分总磷(TP)、溶解态磷(DP)、颗粒态磷(PP)]年际变化及水期特征,基于河流基流分割原理对磷的来源进行了解析.结果表明,18年来朱沱TP和PP浓度与通量丰水期高于平、枯水期;PP与SS正相关性的规律未变.从2002~2019年,TP、PP和DP浓度与通量总体上呈先升高后下降趋势,且向家坝水库运行是SS、输沙量和TP、PP浓度与通量下降的重要时间节点.相对于2002~2012年,2014~2019年SS与输沙量分别下降了94%和77%,TP与PP浓度分别下降了46%和70%,TP与PP通量分别下降了58%和74%,下降主要发生于丰水期,其次是平水期.两座水库形成后,水沙关系和磷赋存形态都发生了巨大变化,DP占比显著升高,PP占比显著下降,枯水期和平水期的磷已由颗粒态为主转变为以溶解态为主.水沙条件改变是磷浓度、通量及形态发生显著变化的主要驱动力.向家坝水库运行前,汇水次级流域中,金沙江对朱沱TP总负荷和面源负荷的贡献率最大,运行后变为岷江贡献率最大.2017~2019朱沱断面总磷负荷平均为3.575万t·a^(-1)(扣除天然背景值后),其中面源和点源贡献率分别为68%和32%;朱沱TP总负荷中岷江贡献率占49%,面源负荷中岷江贡献率占43%,点源负荷中岷江贡献率占62%.长江三峡水库上游磷污染治理的重点区域是岷沱江流域.

关键词：长江梯级水库磷通量形态源解析

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知识网络的结构、演化及热点探测——CSSCI(1998-2011)经济学文献计量分析

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情报科学 2014年第7期32卷 3-8页

作者：马费成刘旻璇武汉大学信息资源研究中心

对六种主要类型的知识网络进行对比,确定了共词网络在探究学科知识内涵的重要作用。选用CSSCI数据库收录的经济学领域72种核心期刊的关键词构筑不同层次的网络,从宏观视角、中观视角以及微观视角全方位地探究了我国经济学的知识结构、... 详细信息

对六种主要类型的知识网络进行对比,确定了共词网络在探究学科知识内涵的重要作用。选用CSSCI数据库收录的经济学领域72种核心期刊的关键词构筑不同层次的网络,从宏观视角、中观视角以及微观视角全方位地探究了我国经济学的知识结构、演化热点。

关键词：共词网络学科知识经济学可视化计量分析

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Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

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Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong Xu Shoumin xuan Shuai Chen Dan liu Qian Xiao Jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of Life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

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Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis

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Science China Life Sciences 2025年第1期68卷 103-115页

作者： Xizi Luo Nan Zhang Yuntao liu Beibei Du xuan Wang Tianxu Zhao Bingqiang liu Shishun Zhao Jiazhang Qiu Guoqing Wang State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Basic MedicineJilin University State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Veterinary MedicineJilin University College of Mathematics Jilin University Bioinformatic Lab School of MathematicsShandong University Department of Cardiology China-Japan Union HospitalJilin University

The coronavirus disease 2019（COVID-19） outbreak caused by the severe acute respiratory syndrome coronavirus-2（SARS-CoV-2） developed into a global health emergency. Systemic microthrombus caused by SARS-CoV-2 infection is a common complication in patients with COVID-19. Cardiac microthrombosis as a complication of SARS-CoV-2 infection is the primary cause of cardiac injury and death in patietns with severe COVID-19. In this study, we performed single-cell sequencing analysis of the right ventricular free wall tissue from healthy donors,patients who died during the hypercoagulable period of characteristic coagulation abnormality（CAC）, and patients who died during the fibrinolytic period of CAC. We collected 61,187 cells enriched in 24 immune cell subsets and 13 cardiac-resident cell subsets. We found that in the course of SARS-CoV-2 infected heart microthrombus, MYO1EhighRASGEF1Bhighmonocyte-derived macrophages promoted hyperactivation of the immune system and initiated the extrinsic coagulation pathway by activating chemokines CCL3, CCL5. This series of events is the main cause of cardiac microthrombi following SARS-CoV-2 infection. In a SARS-CoV-2 infected heart microthrombus, excessive immune activation is accompanied by an increase in cellular iron content, which in turn promotes oxidative stress and intensifies intercellular competition. This induces cells to alter their metabolic environment, resulting in increased sugar uptake via the glycosaminoglycan synthesis pathway. In addition, high levels of reactive oxygen species generated by elevated iron levels promote increased endogenous malondialdehyde synthesis in a subpopulation of cardiac endothelial cells. This exacerbates endothelial cell dysfunction and exacerbates the coagulopathy process.

关键词： SARS-CoV-2 cardiac microthrombosis immune hyperactivation cell competition

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图书馆宣传工作探析

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图书馆论坛 2007年第5期27卷 170-171,106页

作者：刘敏宣任志海贵州省财经学院图书馆贵州贵阳550003 北京大学信息管理系北京100871

对近几年来图书馆宣传工作进行了梳理,从图书馆宣传的内涵、现状、策略等方面进行了总结,指出图书馆宣传是新时期图书馆需要加强和改进的工作之一。

关键词：图书馆形象宣传策略

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The Internet of Things under Federated Learning:A Review of the Latest Advances and Applications

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Computers, Materials & Continua 2025年第1期82卷 1-39页

作者： Jinlong Wang Zhenyu liu Xingtao Yang min Li Zhihan Lyu School of Information and Control Engineering Qingdao University of TechnologyQingdao260043China Anhui Province Key Laboratory of Intelligent Building&Building Energy Saving Anhui Jianzhu UniversityHefei230000China Department of Game Design Uppsala UniversityUppsala75310Sweden

With the rapid development of artificial intelligence,the Internet of Things(IoT)can deploy various machine learning algorithms for network and application *** the IoT environment,many sensors and devices generatemassive data,but data security and privacy protection have become a serious *** learning(FL)can achieve many intelligent IoT applications by training models on local devices and allowing AI training on distributed IoT devices without data *** review aims to deeply explore the combination of FL and the IoT,and analyze the application of federated learning in the IoT from the aspects of security and privacy *** this paper,we first describe the potential advantages of FL and the challenges faced by current IoT systems in the fields of network burden and privacy ***,we focus on exploring and analyzing the advantages of the combination of FL on the Internet,including privacy security,attack detection,efficient communication of the IoT,and enhanced learning *** also list various application scenarios of FL on the ***,we propose several open research challenges and possible solutions.

关键词： Federated learning Internet of Things sensors machine learning privacy security

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