检索结果-南通市图书馆

Ultra-small MoS2 nanodots with rapid body clearance for photothermal cancer therapy

Nano Research 2016年第10期9卷 3003-3017页

作者： Teng liu Yu chao min Gao chao Liang Qian Chen Guosheng Song Liang Cheng Zhuang liu Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & DevicesSoochow University 199 Ren'ai Road Suzhou 215123 China

The clinical translation of many inorganic nanomaterials is severely hampered by toxicity issues because of the long-term retention of these nanomaterials in the body. In this study, we developed a bio-clearable theranostic agent based on ultra-small MoS2 nanodots, which were synthesized by a facile bottom-up approach through one-step solvothermal decomposition of ammonium tetrathiomolybdate. After modification by glutathione （GSH）, the obtained MoS2-GSH nanodots exhibited sub-10-nm hydrodynamic diameters without aggregation in various physiological buffers. Without showing appreciable in vitro toxicity, such MoS2-GSH nanodots with strong near-infrared （NIR） absorbance could induce remarkable photothermal ablation of cancer cells. Upon intravenous （i.v.） injection, efficient tumor accumulation of MoS2-GSH nanodots was observed by photoacoustic imaging, and further confirmed by analysis of the biodistribution of Mo. Notabl）4 the MoS2-GSH nanodots, in contrast to conventional MoS2 nanoflakes with larger sizes, showed rather efficient body clearance via urine, where the majority of the injected dose was cleared within just seven days. Photothermal ablation of tumors on mice was then realized with the MoS2-GSH nanodots, achieving excellent therapeutic efficacy. This study presents a new type of ultra-small nanoparticle with efficient tumor homing/treatment abilities, as well as rapid body clearance behavior, making it promising for cancer theranostics without long-term toxiciW concerns.

关键词： ultra-small MoS2 nanodots photoacoustic imaging rapid body clearance photothermal therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Removal of Cd and Pb with biochar made from dairy manure at low temperature

引用

Journal of Integrative Agriculture 2019年第1期18卷 201-210页

作者： CHEN Zhi-liang ZHANG Jian-qiang HUANG Ling YUAN Zhi-hui LI Zhao-jun liu min-chao Guangdong Engineering Technology Research Center of Heavy Metal Pollution Control and Restoration in Farmland Soil South China Institute of Environmental Sciences School of Environment and Chemistry Wuyi UniversityJiangmen Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture/China-New Zealand Joint Laboratory for Soil Molecular EcologyInstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences

Biochar(BC) derived from waste products is a cost-effective sorbent for remediation of metal-contaminated *** studied the kinetics and adsorption mechanisms for removal of metal ions,such as lead(Pb^(2+)) and cadmium(Cd^(2+)) with *** adsorption capacities of BC for Pb^(2+) and Cd^(2+) increased after alkaline *** highest sorption capacities were 175.53 and 68.08 mg g^(–1),for Pb and Cd,*** Langmuir adsorption isotherm and pseudo second kinetic equation could well fit the adsorption processes,revealing that the sorption mechanisms of Pb^(2+) and Cd^(2+) by BC are complex and predominantly controlled by *** has a higher affinity for Pb than Cd,due to easy hydrolysis of Pb at low ***,precipitation as carbonate minerals(2PbCO_3·Pb(OH)_2 and CdCO_3) and complexation with functional groups(carboxyl and hydroxyl) were also important for adsorption of Pb and Cd by BC.

关键词： biochar kinetics isotherms Pb Cd

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly elastic and degradable vitrimeric elastomers using polycondensation

引用

Chinese Chemical Letters 2024年第3期35卷 434-438页

作者： Yue liu Yongshuang Huang chao Li Guifu Si min Chen Institutes of Physical Science and Information Technology Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of EducationAnhui UniversityHefei 230601China CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

Introducing covalently crosslinked network to polymer matrix can merge the advantages in reprocessing and durability of *** this contribution,a series of high-performance vitrimeric elastomers were achieved via *** topological structures of polymers were tuned by varying the feeding ratios of bisacetoacetate,hex–substituted bisacetoacetate,bisamine and tris(2-aminoethyl)*** these structural manipulations,the vitrimeric elastomers presented great elastic recovery properties(strain recovery value up to 80%)benefiting from the introduction of long chain ***,the elastomers exhibited excellent reprocessing property,water vapor/oxygen barrier and adhesive ***,the elastomers could be degraded into monomer under acid conditions which enabled the elastomer synthesis again in closed loop recycling *** ease of the polycondensation in this work to prepare highly elastic and recyclable vitrimeric elastomers demonstrated exciting opportunities for the synthesis of sustainable polymers.

关键词： Polycondensation Vitrimeric elastomers Highly elastic Degradable polymers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Thioacetamide Additive Homogenizing Zn Deposition Revealed by In Situ Digital Holography for Advanced Zn Ion Batteries

引用

Nano-Micro Letters 2024年第6期16卷 261-275页

作者： Kaixin Ren min Li Qinghong Wang Baohua liu Chuang Sun Boyu Yuan chao Lai Lifang Jiao chao Wang School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhou 221116JiangsuPeople’s Republic of China Jiangsu Key Laboratory of Advanced Laser Materials and Devices School ofPhysics and Electronic EngineeringJiangsu Normal UniversityXuzhou 221116JiangsuPeople’s Republic of China Key Laboratory of Advanced Energy Materials Chemistry(ministry of Education) Nankai University300071 TianjinPeople’s Republic of China

Zinc ion batteries are considered as potential energy storage devices due to their advantages of low-cost,high-safety,and high theoretical ***,dendrite growth and chemical corrosion occurring on Zn anode limit their *** problems can be tackled through the optimization of the ***,the screening of electrolyte additives using normal electrochemical methods is time-consuming and ***,a fast and simple method based on the digital holography is *** can realize the in situ monitoring of electrode/electrolyte interface and provide direct information concerning ion concentration evolution of the diffusion *** is effective and time-saving in estimating the homogeneity of the deposition layer and predicting the tendency of dendrite growth,thus able to value the applicability of electrolyte *** feasibility of this method is further validated by the forecast and evaluation of thioacetamide *** on systematic characterization,it is proved that the introduction of thioacetamide can not only regulate the interficial ion flux to induce dendrite-free Zn deposition,but also construct adsorption molecule layers to inhibit side reactions of Zn *** easy to operate,capable of in situ observation,and able to endure harsh conditions,digital holography method will be a promising approach for the interfacial investigation of other battery systems.

关键词： Digital holographic microscopy In situ observation Electrode/electrolyte interface Zn dendrites Screening electrolyte additives

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A highly reduced Mo_(74) polyoxometalate featuring high proton conductivity accessed by building block strategy

引用

Science China Chemistry 2024年第3期67卷 862-868页

作者： Shi-Yi liu Xue-Xin Li Wei-chao Chen Kui-Zhan Shao Xin-Long Wang chao Qin Zhong-min Su Key Laboratory of Polyoxometalate and Reticular Material Chemistry of ministry of Education Department of ChemistryNortheast Normal UniversityChangchun 130024China State Key Laboratory of Supramolecular Structure and Materials Institute of Theoretical ChemistryCollege of ChemistryJilin UniversityChangchun 130021China

Highly reduced polyoxometalates(POMs) are predicted to be used as rather high energy density materials;however,it still suffers from the limited cluster species and reduction *** we demonstrate that it is possible to employ the building block strategy to generate a highly reduced polyoxomolybdate(C_(2)H_(8)N)_(14)(NH_(4))_(4)H_(14)[Mo_(48)-ⅤMo_(26)ⅥO_(202)(OH)_(12)(SO_(4))_(6)]·46H_(2)O(Mo_(74)).The fundamental Mo-based{Mo_x}(x=4,5,and 6) building blocks,which are templated by tetra-coordinated anions{MoO_(4)}or{SO_(4)},not only lay foundation for the formation of Mo_(74) featuring an unprecedented reduction ratio of 65%,but also give rise to SBBs-mediated(secondary building blocks) supramolecular dense packing interactions among the isolated Mo_(74) clusters that are favorable for proton ***,high proton conductivity(2.04×10^(-2)S cm^(-1)) had been realized at 50℃ and 90% relative humidity,revealing one of the well-known POMs-based crystalline proton conducting *** result highlights that this building block approach possesses great potential in producing highly reduced POM systems that can achieve controllable reduced ratio and desirable properties.

关键词： polyoxometalate building block molybdenum highly reduced state proton conduction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tracked robot with underactuated tension-driven RRP transformable mechanism:ideas and design

引用

Frontiers of Mechanical Engineering 2024年第1期19卷 85-104页

作者： Ran XU chao liu School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China Key Laboratory of Vehicle Advanced Manufacturing Measuring and Control Technology(Ministry of Education)Beijing Jiaotong UniversityBeijing 100044China

Robots with transformable tracked mechanisms are widely used in complex terrains because of their high adaptability,and many studies on novel locomotion mechanisms have been conducted to make them able to climb higher *** underactuated transformable mechanisms for tracked robots could decrease the number of actuators used while maintaining the flexibility and obstacle-crossing capability of these robots,and increasing their cost ***,the underactuated tracked robots have appreciable research *** this paper,a novel tracked robot with a newly proposed underactuated revolute‒revolute‒prismatic(RRP)transformable mechanism,which is inspired by the sit-up actions of humans,was *** newly proposed tracked robot has only two actuators installed on the track pulleys for moving and does not need extra actuators for ***,it could concentrate the track belt’s tension toward one side,and the unbalanced tension would drive the linkage mechanisms to change its *** this method,the proposed underactuated design could change its external shape to create support points with the terrain and move its center of mass actively at the same time while climbing obstacles or crossing other kinds of terrains,thus greatly improving the climbing capability of the *** geometry and kinematic relationships of the robot and the crossing strategies for three kinds of typical obstacles are *** the basis of such crossing motions,the parameters of links in the robot are designed to make sure the robot has sufficient stability while climbing ***-crossing dynamic simulations were run and analyzed to prove the feasibility of the robot.A prototype was built and *** show that the proposed robot could climb platforms with heights up to 33.3%of the robot’s length or cross gaps with widths up to 43.5%of the robot’s length.

关键词： mechanical design tracked robot underactuated mechanisms RRP mechanism obstacle crossing strategy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pillar uplift of a subway station caused by foundation pit excavation in deep soft soil area

引用

Yantu Lixue/Rock and Soil Mechanics 2020年 41卷 397-404页

作者： Gao, Yan-Bin Yang, Zheng-Yuan liu, chao-min Li, Wen-Yong College of Civil Engineering Tongji University Shanghai 200092 China Construction Management Center Shanghai Shentong Metro Group Company Shanghai 200092 China

The steel pillars are usually used as vertical supports to maintain the stability of the internal support in the braced excavation. As a case study, the pillar uplift in a subway station, with the excavation depth of 17.6 m, located in a thick soft layer of paleochannel with a total thickness up to 40 m in Shanghai are studied. When the excavation reaches to the bottom of pit, the monitored uplift δhv in the standard section is in the range of 60-80 mm, causing cracks in some reinforced concrete layer. The uplift process of steel pillars is roughly divided into three stabilization stages: the early low-speed stage (Fssv and the maximum lateral displacement of the diaphragm wall(δhhm). The lateral displacement of the deep soil at the bottom of the diaphragm wall causes a larger δhv/δhhm of the standard section in the late stages of excavation. The uplift amount of the steel pillar for the end well is within 30 mm and much smaller than that of the standard section. There is no obvious lateral displacement in the soil at the bottom of the wall, showing a significant spatial effect. In addition, the uplift amount of the steel pillar decreases along the excavation direction during the stepped excavation mode. It is necessary to pay more attention on the influence of excavation mode and pouring process of slab on the uplift of the pillars. © 2020, Science Press. All right reserved.

关键词： Safety factor

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Constructing the Impossible Differential of Type-II GFN with Boolean Function and Its Application to WARP

引用

Chinese Journal of Electronics 2024年第1期33卷 80-89页

作者： Jiali SHI Guoqiang liu chao LI College of Liberal Arts and Sciences National University of Defense Technology Hunan Engineering Research Center of Commercial Cryptography Theory and Technology Innovation State Key Laboratory of Information Security Institute of Information Engineering

Type-Ⅱ generalized Feist el network(GFN) has attracted a lot of attention for its simplicity and high *** differential attack is one of the powerful cryptanalytic approaches for word-oriented block ciphers such as Feistel-like *** deduce the impossible differential of Type-Ⅱ GFN by analyzing the Boolean function in the middle *** main idea is to investigate the expression with the variable representing the plaintext(ciphertext) difference words for the internal state *** adopting the miss-in-the-middle approach,we can construct the impossible differential of Type-Ⅱ *** an illustration,we apply this approach to WARP,a lightweight 128-bit block cipher with a 128-bit key which was presented by Banik et *** SAC *** structure of WARP is a 32-branch Type-Ⅱ ***,we find two 21-round truncated impossible differentials and implement a 32-round key recovery attack on *** the 32-round key recovery attack on WARP,some observations are used to mount an effective *** the advantage of the early abort technique,the data,time,and memory complexities are 2125.69chosen plaintexts,2126.6832-round encryptions,and 2100-bit,*** the best of our knowledge,this is the best attack on WARP in the single-key scenario.

关键词： Ciphers Boolean functions Parallel processing Complexity theory

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Design of efficient thermoelectric generators

引用

Science China Materials 2024年第1期67卷 377-378页

作者： min liu Yanzhong Pei Interdisciplinary Materials Research Center School of Materials Science and EngineeringTongji UniversityShanghai 201804China

Thermoelectricity,which enables direct conversion between heat and electricity,undergoes impressive developments in recent decades,and is particularly promising for recovering low-grade heat of<600 K[1,2].Currently,only Bi2Te3-based thermoelectric devices are commercialized[3].However,the scarcity of tellurium(Te)(Fig.1a)is the main *** leads to numerous recent efforts on the development of efficient nonBi2Te3 thermoelectrics as potential alternatives,and successful examples(Fig.1b)include Mg3Sb2-alloys[2,3]and MgAgSb[1,2].

关键词： enable efficient electricity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Effect and Mechanism of Fructus lycii on Improvement of Exercise Fatigue Using a Network Pharmacological Approach with in vitro Experimental Verification

引用

Biomedical and Environmental Sciences 2024年第1期37卷 42-53页

作者： JI Xiao Ning liu Zhao Ping ZHANG chao Zheng CHEN min LIANG Jiang LU Jiang ZHANG Lei National Resource Center for Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China China National Center for Food Safety Risk Assessment Beijing 100022China Chinese Center for Disease Control and Prevention Beijing 102206China

Objective This study aimed to investigate the effect and underlying mechanism of Fructus lycii in improving exercise *** A network pharmacological approach was used to explore potential mechanisms of action of Fructus *** muscle C2C12 cells and immunofluorescence were employed to verify the effect and mechanism of the representative components in Fructus lycii predicted by network pharmacological *** Six potential active components,namely quercetin,β-sitosterol,stigmasterol,7-Omethylluteolin-6-C-beta-glucoside_qt,atropine,and glycitein,were identified to have potency in improving exercise fatigue via multiple pathways,such as the PI3K-Akt,neuroactive ligand-receptor interaction,IL-17,TNF,and MAPK signaling *** immunofluorescence results indicated that quercetin,a significant active component in Fructus lycii,increased the mean staining area of 2-NBDG,TMRM,and MitoTracker,and decreased the area of CellRox compared to the ***,the protein expression levels of p-38 MAPK,p-MAPK,p-JNK,p-PI3K,and p-AKT markedly increased after quercetin *** Fructus lycii might alleviate exercise fatigue through multiple components and *** these,quercetin appears to improve exercise fatigue by enhancing energy metabolism and reducing oxidative *** PI3K-AKT and MAPK signaling pathways also appear to play a role in this process.

关键词： Fructus lycii Exercise fatigue Network pharmacology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：