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New Record Ocean Temperatures and Related Climate Indicators in 2.2.

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Advances in Atmospheric sciences 2024年第6期41卷 1068-1082页

作者： Lijing CHENG John ABRAHAM Kevin E.TRENBERTH Tim BOYER Michael EMANN jiang zhu Fan WANG Fujiang YU Ricardo LOCARNINI John FASULLO fei ZHENG Yuanlong LI Bin ZHANG Liying WAN Xingrong CHEN Dakui WANG Licheng feng Xiangzhou SONG Yulong liu Franco RESEGHETTI Simona SIMONCELLI Viktor GOURETSKI Gengxin CHEN Alexey MISHONOV Jim REAGAN Karina VON SChuCKMANN Yuying PAN Zhetao TAN Yujing zhu Wangxu WEI Guancheng LI Qiuping REN Lijuan CAO Yayang LU International Center for Climate and Environment sciences Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China university of St.Thomas School of EngineeringMinnesota 55105USA NSF National Center for Atmospheric Research BoulderColorado 80307USA university of Auckland Auckland 1010New Zealand National Oceanic and Atmospheric Administration National Centers for Environmental InformationSilver SpringMaryland 20910USA Department of Earth and environmental Science University of PennsylvaniaPhiladelphiaPennsylvania 19104USA Institute of Oceanology Chinese Academy of SciencesQingdao 266071China National Marine environmental Forecasting Center Ministry of Natural Resources of ChinaBeijing 100081China Oceanographic Data Center Chinese Academy of SciencesQingdao 266071China college of Oceanography Hohai UniversityNanjing 210098China National Marine Data and Information Service Tianjin 300171China Italian National Agency for New Technologies Energy and Sustainable Economic DevelopmentS.Teresa Research CenterLerici 19032Italy Istituto Nazionale di Geofisica e Vulcanologia Sede di BolognaBologna 40128Italy South china Sea Institute of Oceanology Chinese Academy of SciencesGuangzhou 510301China ESSIC/CISESS-MD University of MarylandCollege ParkMD20740USA Mercator Ocean International Toulouse 31400France Eco-environmental Monitoring and Research Center Pearl River Valley and South China Sea Ecology and Environment AdministrationMinistry of Ecology and EnvironmentPRCGuangzhou 510611China National Meteorological Information Center China Meteorological AdministrationBeijing 100081China International Research Center of Big Data for Sustainable Development Goals Beijing 100094China

The global physical and biogeochemical environment has been substantially altered in response to increased atmospheric greenhouse gases from human *** 2.2.,the sea surface temperature(SST)and upper 2.00 m ocean heat content(OHC)reached record *** 0–2.00 m OHC in 2.2. exceeded that of 2.2. by 15±10 ZJ(1 Zetta Joules=102. Joules)(updated IAP/CAS data);9±5 ZJ(NCEI/NOAA data).The Tropical Atlantic Ocean,the Mediterranean Sea,and southern oceans recorded their highest OHC observed since the *** with the onset of a strong El Niño,the global SST reached its record high in 2.2. with an annual mean of~0.2.℃ higher than 2.2. and an astounding>0.3℃ above 2.2. values for the second half of *** density stratification and spatial temperature inhomogeneity indexes reached their highest values in 2.2..

关键词： ocean heat content salinity stratification global warming climate

One-year status of hepatic venous pressure gradient measurement from 85 hospitals in china

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Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao Wang Ting Cui Linpeng Zhang Zhiping Yan Lei Li Jinjun Chen Junhui Sun hua Xiang He zhu Hao Wu Jiancuo Gengzang feng Zhang Wei Wu Guohong Cao Wuhua Guo Haibin Shi hui Xue Guangjun huang Qiang Yu Meng Niu huiling Xiang Derun Kong Wei Gou Xuefeng Luo Fuliang He Min Yuan Wei liu Yong Wang Hongjie hu Xiaoli zhu Tao Yu Qinxue Sun Wei Qu Ting Lu Deqiang Ma Li Zhang Jun Ma Jun Yang Ketao Mu Xiaoliang zhu Kai Xiong huiguo Ding Shengjuan Yao Mingsheng huang Fang Wang Zexin Wang Yong huang Jianan Li Hongfeng Yi Birun huang Zhongwei Zhao Duiping feng Yanming Lei Changlong Hou Wenbo Guo Shirong liu Gaojun Teng Kangshun zhu Fan Wu Xiaogang hu Wenfeng Zhang Shaoqi Yang Zhouchao hu Pengfei Pang Shaowu zhuang Weidong Wang Qingliang zhu Kunpeng Zhang Chengyu liu Dongliang Li Chao Ma Hong jiang Xingong Zhao Weixin Ren Zhiwei Wang Lei Yu Fuhuang Lin Chaoguang Yan feng Wang Lei Yu hui huan Wenyong Shen Shaofei He Chengda Zhang Jinlun Bao jiangtao liu Jun Wu Jianbo Zhao Jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina Department of Interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina Department of Intervention Taiyuan Third People's HospitalTaiyuanShanxiChina Department of Intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina Department of Interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic Intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina Department of Intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina Department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina Department of Intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina Department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina Department of Intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina Department of Interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in china in ***:We investigated the overall status of HVPG technology in china-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in china used HVPG technology in 2.2. distributed across 2. provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2.2.,of which 2.13 cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2.2..9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82.87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in china and confirmed that some medical institutions in china have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey

Will the Historic Southeasterly Wind over the Equatorial Pacific in March 2.2. Trigger a Third-year La Niña Event?

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Advances in Atmospheric sciences 2023年第1期40卷 6-13页

作者： Xianghui FANG fei ZHENG Kexin LI Zeng-Zhen hu Hongli REN Jie WU Xingrong CHEN Weiren LAN Yuan YUAN Licheng feng Qifa CAI {2. zhu Department of Atmospheric and Oceanic sciences&Institute of Atmospheric sciences Fudan UniversityShanghai 200438China International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044China Climate Prediction Center NCEP/NWS/NOAACollege ParkMD 20740USA State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China National Climate Center Beijing 100081China National Marine environmental Forecasting Center Beijing 100081China Mailbox 5111 Beijing 100094China

Based on the updates of the Climate Prediction Center and International Research Institute for Climate and Society(CPC/IRI)and the china Multi-Model Ensemble(CMME)El Niño-Southern Oscillation(ENSO)Outlook issued in April 2.2.,La Niña is favored to continue through the boreal summer and fall,indicating a high possibility of a three-year La Niña(2.2.-2.).It would be the first three-year La Niña since the 1998-2.01 event,which is the only observed three-year La Niña event since *** examining the status of air-sea fields over the tropical Pacific in March 2.2.,it can be seen that while the thermocline depths were near average,the southeasterly wind stress was at its strongest since ***,based on a quaternary linear regression model that includes various relevant air-sea variables over the equatorial Pacific in March,we argue that the historic southeasterly winds over the equatorial Pacific are favorable for the emergence of the third-year La Niña,and both the anomalous easterly and southerly wind stress components are important and contribute~50%of the third-year La Niña growth,***,the possible global climate impacts of this event are discussed.

关键词： El Niño-Southern Oscillation three-year La Niña strongest southeasterly wind air-sea interaction

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen hua-Xing Chen huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geo{2. Beijing china university of Geo{2. WuhanHubei china university of Mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhu&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2.s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2.15)and the Conceptual Design Report(CDR,2.18),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2.2.-2.2.,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2.30s.

关键词： initiated exceeding precise

The Chinese Society of Clinical Oncology(CSCO)clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

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Cancer Communications 2021年第11期41卷 1195-1227页

作者： Ling-Long Tang Yu-Pei Chen Chuan-Ben Chen Ming-Yuan Chen Nian-Yong Chen Xiao-Zhong Chen Xiao-Jing Du Wen-feng Fang Mei feng Jin Gao {2. Han Xia He Chao-Su hu De-sheng hu Guang-Yuan hu Hao jiang Wei jiang feng Jin Jin-Yi Lang Jin-Gao Li Shao-Jun Lin Xu liu Qiu-Fang liu Lin Ma Hai-Qiang Mai Ji-Yong Qin Liang-Fang Shen Ying Sun Pei-Guo Wang Ren-Sheng Wang Ruo-Zheng Wang Xiao-Shen Wang Ying Wang hui Wu Yun-{2. Xia Shao-Wen Xiao Kun-Yu Yang Jun-Lin Yi Xiao-Dong zhu Jun Ma Department of Radiation Oncology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer Center651 Dongfeng Road EastGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Fujian Provincial Cancer HospitalFujian Medical University Department of Radiation OncologyTeaching Hospital of Fujian Medical University Provincial Clinical CollegeCancer Hospital of Fujian Medical UniversityFuzhouFujian 350014P.R.China Department of Nasopharyngeal Carcinoma State Key Laboratory of Oncology in South ChinaCollaborative Innovation Centre for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Cancer CenterWest China HospitalSichuan UniversityChengduSichuan 610041P.R.China Cancer Hospital of the university of Chinese Academy of sciences(Zhe{2. Cancer Hospital)Institute of Cancer and Basic Medicine(IBMC)Chinese Academy of sciences HangzhouZhejiang 310000P.R.China State Key Laboratory of Oncology in South china Collaborative Innovation Center for Cancer MedicineMedical Oncology DepartmentSun Yat-Sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Sichuan Cancer Hospital and InstituteSichuan Cancer CenterSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan 610041P.R.China Department of Radiation Oncology Anhui Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui 230001P.R.China Department of Clinical Laboratory Affiliated Cancer Hospital of Nanjing Medical UniversityJiangsu Cancer HospitalJiangsu Institute of Cancer ResearchNanjingJiangsu 210000P.R.China Department of Radiation Oncology Fudan University Shanghai Cancer CenterShanghai 200032P.R.China Department of Radiotherapy Hubei Cancer HospitalTong

Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North *** develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the *** on the findings of evidencebased medicine in china and abroad,domestic experts have iteratively developed these guidelines to provide proper management of ***,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC.

关键词： Chinese Society of Clinical Oncology CSCO Nasopharyngeal carcinoma Diagnosis Staging Risk Radiotherapy Chemotherapy Surgery Immunotherapy

2.2. Roadmap on two-dimensional nanomaterials for environmental catalysis

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Chinese Chemical Letters 2019年第12期30卷 2065-2088页

作者： Yulu Yang Mingguang Wu Xingwang zhu hui Xu Si Ma Yongfeng Zhi Hong Xia Xiaoming {2. Jun Pan Jie-Yinn Tang Siang-Piao Chai Leonardo Palmisano Francesco Parrino Junli {2. Jianzhong Ma Ze-Lin Wang Ling Tan Yu-fei Zhao Yu-fei Song Pardeep Singh Pankaj Raizada Deli jiang Di Li R.A.Geioushy Jizhen Ma Jintao Zhang Song hu Rongjuan feng Gang {2. Minghua {2. Zhenhua Li Mingfei Shao Neng Li Jiahe Peng Wee-Jun Ong Nikolay Kornienko Zhenyu Xing Xiujun Fan Jianmin Ma School of Physics and Electronics Hunan UniversityChangsha 410082China School of the Environment and Safety Engineering Institute for Energy ResearchJiangsu UniversityZhenjiang 212013China college of Chemistry Jilin UniversityChangchun 130012China State Key Laboratory on Integrated Optoelectronics College of Electronic Science and TechnologyJilin UniversityChangchun 130012China Key Laboratory for Powder Metallurgy Central South UniversityChangsha 410083China Multidisciplinary Platform of Advanced Engineering Chemical Engineering DisciplineSchool of EngineeringMonash UniversityJalan Lagoon SelatanBandar SunwaySelangor 47500Malaysia university of Palermo Department of EngineeringPalermo 90128Italy university of Trento Department of Industrial EngineeringTrento 38123Italy School of Materials Science and Engineering Shaanxi University of Science&TechnologyXi'an 710021China college of Bioresources Chemistry and Materials Engineering Shaanxi University of Science&TechnologyXi'an 710021China State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China School of Chemistry Faculty of Basic SciencesShoolini UniversitySolanHP 173229India Himalayan Centre for Excellence in Nanotechnology Shoolini UniversitySolanmHP 173229India School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China Institute for Energy Research Jiangsu UniversityZhenjiang 212013China Nanomaterials and Nanotechnology Department Advanced Materials DivisionCentral Metallurgical R&D Institute(CMRDI)Cairo 11421Egypt Key Laboratory for Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical Engineering Shandong UniversityJi'nan 250100China National Laboratory for Molecular Science(BNLMS) CAS Laboratory of ColloidInterface and Chemical ThermodynamicsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence i

environmental catalysis has drawn a great deal ofattention due to its clean ways to produce useful chemicals or carry out some chemical *** and electrocatalysis play important roles in these *** can decompose and remove organic pollutants from the aqueous environment,and prepare some fine ***,they also can carry out some important reactions,such as 02.reduction reaction(ORR),O2.evolution reaction(OER),H2.evolution reaction(HER),CO2.reduction reaction(C02.RR),and N2.fixation(NRR).For catalytic reactions,it is the key to develop high-performance catalysts to meet the demand fortargeted *** recentyears,two-dimensional(2.D) materials have attracted great interest in environmental catalysis due to their unique layered structures,which offer us to make use of their electronic and structural *** progress has been made so far,including graphene,black phosphorus,oxides,layered double hydroxides(LDHs),chalcogenides,bismuth-based layered compounds,MXenes,metal organic frameworks(MOFs),covalent organic frameworks(COFs),and *** content drives us to invite many famous groups in these fields to write the roadmap on two-dimensional nanomaterials for environmental *** hope that this roadmap can give the useful guidance to researchers in future researches,and provide the research directions.

关键词： Two-dimensional materials Graphene Black phosphorus C3N4 Metal organic frameworks MXenes

Nucleic acids analysis

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Science china Chemistry 2021年第2期64卷 171-203页

作者： Yongxi Zhao Xiaolei Zuo Qian Li feng Chen Yan-Ru Chen Jinqi Deng Da Han Changlong Hao Fujian huang Yanyi huang Guoliang Ke hua Kuang Fan Li jiang Li Min Li Na Li Zhenyu Lin Dingbin {2. Juewen {2. Libing {2. Xiaoguo {2. Chunhua Lu Fang Luo Xiuhai Mao Jiashu Sun Bo Tang fei Wang Jianbin Wang Lihua Wang Shu Wang Lingling Wu Zai-Sheng Wu Fan Xia Chuanlai Xu Yang Yang Bi-feng Yuan Quan Yuan Chao Zhang Zhi zhu Chaoyong Yang Xiao-Bing Zhang huanghao Yang Weihong Tan Chunhai Fan Institute of Analytical Chemistry and Instrument for Life Science The Key Laboratory of Biomedical Information Engineering of Ministry of EducationSchool of Life Science and TechnologyXi’an Jiaotong UniversityXi’an 710049China Institute of Molecular Medicine Shanghai Key Laboratory for Nucleic Acid Chemistry and NanomedicineRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesInstitute of Translational MedicineShanghai Jiao Tong UniversityShanghai 200240China Cancer Metastasis Alert and Prevention Center Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and ChemotherapyState Key Laboratory of Photocatalysis on Energy and EnvironmentCollege of ChemistryFuzhou UniversityFuzhou 350108China CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China State Key Lab of Food Science and Technology International Joint Research Laboratory for Biointerface and BiodetectionSchool of Food Science and TechnologyJiangnan UniversityWuxi 214122China Faculty of Materials Science and Chemistry Engineering Research Center of Nano-Geomaterials of Ministry of EducationChina University of GeosciencesWuhan 430074China college of Chemistry and Molecular Engineering Biomedical Pioneering Innovation Center(BIOPIC)Beijing Advanced Innovation Center for Genomics(ICG)Peking-Tsinghua Center for Life SciencesPeking UniversityBeijing 100871China State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Division of Physical Biology CAS Key Laboratory of Interfacial Physics and TechnologyShanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai 201800China Bioimaging Center Shanghai Synchrotron Radiation FacilityZhangjiang LaboratoryShanghai Advanced

Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic *** the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological *** this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided.

关键词： nucleic acids analysis signal amplification DNA nanotechnology aptamer biosensing

A chromosome-level genome assembly of rugged rose (Rosa rugosa) provides insights into its evolution, ecology, and floral characteristics

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Horticulture Research 2021年第1期8卷 1939-1951页

作者： fei Chen Liyao Su Shuaiya hu Jia-Yu Xue hui liu Guanhua liu Yifan jiang Jianke Du Yushan Qiao Yannan Fan huan liu Qi Yang Wenjie Lu zhu-Qing Shao Jian Zhang Liangsheng Zhang feng Chen Zong-Ming(Max)Cheng college of Horticulture Nanjing Agricultural UniversityNanjing 210095China Academy for Advanced Interdisciplinary Studies Nanjing Agricultural UniversityNanjing 210095China BGI-Shenzhen Beishan Industrial ZoneYantian DistrictShenzhen 518083China Department of Biology University of CopenhagenCopenhagenDenmark Grandomics Biosciences Co. LtdWuhanChina School of Life sciences Nanjing UniversityNanjingChina college of life science Nantong UniversityNantongChina Genomics and Genetic Engineering Laboratory of Ornamental Plants College of Agriculture and BiotechnologyZhejiang UniversityHangzhouChina Department of plant sciences University of TennesseeKnoxvilleTNUSA

Rosa rugosa,commonly known as rugged rose,is a perennial ornamental *** produces beautiful flowers with a mild fragrance and colorful seed *** many other cultivated roses,*** adapts to a wide range of habitat types and harsh environmental conditions such as salinity,alkaline,shade,drought,high humidity,and frigid ***,we produced and analyzed a high-quality genome sequence for *** to understand its ecology,floral characteristics and *** HiFi reads were initially used to construct the draft genome of ***,and then Hi-C sequencing was applied to assemble the contigs into 7 *** obtained a 382.6Mb genome encoding 39,704 protein-coding *** genome of *** appears to be conserved with no additional whole-genome duplication after the gamma whole-genome triplication(WGT),which occurred~100 million years ago in the ancestor of core *** on a comparative analysis of the high-quality genome assembly of *** and other high-quality Rosaceae genomes,we found a unique large inverted segment in the Chinese rose *** and a retroposition in strawberry caused by post-WGT *** also found that floral development-and stress response signaling-related gene modules were retained after the *** MADS-box genes involved in floral development and the stress-related transcription factors DREB2.-INTERACTING PROTEIN 2.DRIP2.and PEPTIDE TRANSPORTER 3(PTR3)were found to be positively selected in evolution,which may have contributed to the unique ability of this plant to adapt to harsh *** summary,the high-quality genome sequence of *** provides a map for genetic studies and molecular breeding of this plant and enables comparative genomic studies of Rosa in the near future.

关键词： breeding characteristics evolution

Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in china

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Biomedical and environmental sciences 2020年第12期33卷 893-905页

作者： MA Yan zhu Dong Shan CHEN Ren Bo SHI Nan Nan liu Si Hong FAN Yi Pin WU Gui hui YANG Pu Ye BAI {2. feng CHEN Hong CHEN Li Ying feng Qiao GUO Tuan Mao HOU Yong hu Gui Fen hu Xiao Mei hu Yun Hong huANG Jin huANG Qiu hua huANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong liu Hong De liu Jin Ping liu Zhang MA Yu Ting MAO Ya MO liu Fen NA hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun zhu Jun Teng zhu Tian Qing ZHANG hua Min WANG Yan Ping WANG Yong Yan 无 Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Centre for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Tuberculosis The Public Health Clinical Center of ChengduChengdu 610066SichuanChina Department of Infectious Disease Shaanxi Infectious Disease HospitalXi'an 610113ShaanxiChina Department of Infectious Disease Yulin Chinese Medicine HospitalYulin 719000ShaanxiChina President's Office The First Hospital of QiqiharQiqihar 161005HeilongjiangChina Department of Traditional Chinese Medicine Shangluo Central HospitalShangluo 726000ShaanxiChina Department of Traditional Chinese Medicine The People's Hospital of QitaiheQitaihe 154603HeilongjiangChina Department of Scientific Research Xianyang Central HospitalXianyang 712000ShaanxiChina Department of traditional Chinese medicine The First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230012AnhuiChina Department of Infectious Disease Heping Hospital Affiliated to Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Traditional Chinese Medicine Langfang Hospital of Chinese MedicineLangfang 065000HeibeiChina Department of Traditional Chinese Medicine Xingtai Hospital of Chinese MedicineXingtai 054001HeibeiChina Department of Traditional Chinese Medicine The People's Hospital of Guangxi Zhuang Autonomous RegionNanning 168600GuangxiChina Department of Traditional Chinese Medicine The First People'sHospital of FangchenggangFangchenggang 538001GuangxiChina Department of Traditional Chinese Medicine Mianyang Hospital of Traditional Chinese MedicineMianyang 621000SichuanChina Department of Traditional Chinese Medicine Liuzhou People's HospitalLiuzhou 545006GansuChina Department of Traditional Chinese Medici

Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains *** A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in china. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of *** Overall, 158(13.6%) patients were diagnosed with severe illness and 32.2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32., type 2.diabetes(T2.DM)(3.57, 2.32.5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–2..96), hyperlipidemia(2.15, 1.2.–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–2..10)were independently linked to increased odds of being severely ill. T2.DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.2.–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–2..64) within two *** Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes.

关键词： Comorbidities COVID-19 Severity Gender Age Treatment outcome