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超声内镜引导下细针注射治疗胰腺以外腹腔脏器囊肿的初步疗效

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中华消化内镜杂志 2024年第4期41卷 310-312页

作者：谭玉勇楚毅罗敏刘德良周雨迁中南大学湘雅二医院消化内科中南大学消化病研究中心湖南省消化疾病临床医学研究中心长沙410011

2017年8月至2022年8月间,在中南大学湘雅二医院消化内科共8例胰腺以外腹腔脏器组织囊肿患者接受了超声内镜引导下细针注射治疗,其中2例肝囊肿、2例脾囊肿、3例肾囊肿、1例胃胰间隙囊肿,8例患者共行11例次注射治疗,其中无水乙醇注射2例... 详细信息

2017年8月至2022年8月间,在中南大学湘雅二医院消化内科共8例胰腺以外腹腔脏器组织囊肿患者接受了超声内镜引导下细针注射治疗,其中2例肝囊肿、2例脾囊肿、3例肾囊肿、1例胃胰间隙囊肿,8例患者共行11例次注射治疗,其中无水乙醇注射2例次、聚桂醇注射9例次,注射成功率100.0%(11/11)。随访3个月至5年,5例患者囊肿完全消失,其余3例患者囊肿缩小50%或以上。以上结果初步证实,对于胰腺以外腹腔脏器组织囊肿,超声内镜引导下细针注射治疗具有较好的临床疗效。

关键词：囊肿肝囊肿肾囊肿脾囊肿超声内镜引导下细针注射

Functions of ULK1 in autophagy and non-autophagy pathways and its implications in human physiology and disease

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BIOCELL 2020年第4期44卷 535-543页

作者： LINNA TAN YUYONG TAN deliang liu Department of Gastroenterology the Second Xiangya HospitalChangsha410011China Research Center of Digestive Disease Central South UniversityChangsha410011China

ULK1(unc-51 like autophagy activating kinase 1),a mammalian serine/threonine kinase,is a key component of autophagy initiation complex and helps to induce all types of *** autophagy is a process in which,through the interactions of a series of autophagy-related proteins,damaged organelles or misfolded proteins are engulfed by autophagosomes and then merged with lysosomes to be ***,canonical autophagy is an important constituent part of the cellular“quality control.”Besides,accumulating evidence indicates that ULK1 exerts autophagy-independent effects in a cell-specific *** example,ULK1 facilitates neurite elongation through the regulation of endoplasmic reticulum(ER)–Golgi trafficking in neurons,stimulates phosphopentose pathway to help NADPH(nicotinamide adenine dinucleotide phosphate hydrogen)production,and acts as a duplex regulator in type I IFN(type I interferon)induced innate immune *** the importance and diversity of ULK1 in various biological processes,this review aims to present a comprehensive overview of autophagy and non-autophagy related functions of ULK1 in a variety of human physiological,pathological,and disease processes.

关键词： Ubiquitination Axonal extension Cancer Metabolism Immune response Stress

Hydrogeochemical and Isotopic Evidence for Flow Paths of Karst Waters Collected in the Heshang Cave,Central China

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Journal of Earth Science 2015年第1期26卷 149-156页

作者： Xiang Long Ziyong Sun Aiguo Zhou deliang liu School of Environmental Studies China University of Geosciences

Understanding of hydrological processes in caves is important to help us interpret paleoclimate records from speleothems. In this study, we integrated hydrogeological and hydrogeochemical properties to characterize the hydraulic behavior of karst waters in the Heshang Cave, Central China. Using geological and topographical analyses, we identified regional watershed boundaries and hydrogeological connections that were controlled by anticlinal geometry and faults. Water samples were collected from the Heshang Cave and potential recharge sites. Geochemical data of c（Sr^2＋）/c（Ca^2＋） and c（Mg^2＋）/c（Ca^2＋） ratios suggest that the drainage system in Heshang Cave consists of two flow paths. For vadose waters, including drip water and rimstone pool water, c（Sr^2＋）/c（Ca^2＋） ratio ranges from 0.000 6 to 0.001 1, and c（Mg^2＋）/c（Ca^2＋） ratio ranges from 0.97 to 1.1, indicating that recharge was mainly from rainfall infiltration through the overlying Cambrian dolomite stratum. In contrast, slope current and underground river waters have higher c（Sr^2＋）/c（Ca^2＋） ratios （values from 0.002 2 to 0.002 8）, and lower c（Mg2＋）/c（Ca^2＋） ratios （values from 0.50 to 0.64）. These waters show homogeneous isotopic composition （δ^18O： -7.15‰- -6.95‰; δD： -52.73‰- -51.31‰）, implying recharge of allogeneic water from the Xiaocr River via karst conduits that pass through Ordovician limestone and Cambrian dolomite stratum.

关键词： karst water hydrogeochemistry stable isotope flow path Heshang Cave.

Survived Seamount Reveals an in situ Origin for the Central Qiangtang Metamorphic Belt in the Tibetan Plateau

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Journal of Earth Science 2019年第6期30卷 1253-1265页

作者： deliang liu Rendeng Shi Lin Ding Shao-Yong Jiang State Key L aboratory of Geological Processes and Mineral Resources Collaborative Innovation Center for Exploration of Strategic Mineral ResourcesSchool of Earth ResourcesChina University of GeosciencesWuhan 430074China Key L aboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China

The origin of the central Qiangtang metamorphic belt(CQMB)has long been in debate,which is not clear whether this belt is the exhumed Jinsha oceanic plate that had been subducted and underthrusted beneath the Qiangtang Block,or the in situ Longmu Co-Shuanghu suture that separated the south and north Qiangtang *** we report field observations,zircon U-Pb ages and Lu-Hf isotopes,as well as whole rock geochemistry and Sr-Nd isotopes of the Late Triassic volcanic rocks near the Chabo Co within the southern margin of the *** ca.229 Ma Chabo Co volcanic rocks and limestones possess characteristic lithologies of a *** geochemical and isotopic compositions are similar to OIB-type *** other metabasalts(eclogites and blueschists)in the CQMB,the Chabo Co volcanic rocks are OIB-type lavas that did not experience high-grade metamorphism;this is likely because that the Chabo Co seamount was detached from the subducting Longmu Co-Shuanghu oceanic *** work provides new solid evidences for an in situ origin of the CQMB.

关键词： volcanic rock OIB central Qiangtang metamorphic belt Longmu Co-Shuanghu Tibet

Study on estimate method of wave velocity and quality fac-tor to fault seals

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Chinese Science Bulletin 2005年第19期50卷 2243-2248页

作者： LI Zhensheng liu deliang liu Bo YANG Qiang LI dingming The School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China Research Institute of Petroleum Exploration and Development Petro- China Langfang 065007 China

Based on ultrasonic test of fault rocks, the re-sponses for wave velocity and quality factor (Q value) to lithology, porosity and permeability of fault rocks and me-chanical property of faults are studied. In this paper, a new quantitative estimate method of fault seals is originally of-fered. The conclusions are as follows: (1) Wave velocity and Q value increase and porosity decreases with the increase in stress perpendicular to joint; (2) In compressive and com-presso-shear fault rocks that are obviously anisotropic com-pared with their original rocks, the wave velocity and Q value are greater in the direction parallel with foliation, and usually less perpendicular to it. In tensile and tenso-shear fault rocks that are not obviously anisotropic, the wave ve-locity and Q value are under that of original rocks; (3) In foliated fault rocks, the direction with minimal wave velocity and Q value is the best direction for sealing; on the contrary it is the best for flowing; (4) Structural factures develop mainly along foliation, the minimal wave velocity and Q value reflect the flowing capacity in parallel direction to fo-liation, and the maximal wave velocity as well as Q value reflect the sealing capacity in normal direction to foliation. The new estimate method is based upon contrast of wave velocity and Q value between fault rocks and their original rocks, and is divided into three parts that are respectively to identify rock’s lithology, to judge mechanic property of faults and to Judge sealing capacity of faults. Although there is vast scale effect between ultrasonic wave and seismic wave, they have similar regularity of response to fabric and porosity of faults. This research offers new application for seismic data and petrophysical basis for seismological estimation of fault seals. The estimate precision will be improved with the en-hancement of three-dimensional seismic prospecting work.

关键词：超声波各向异性波速品质因素岩石学渗透性

基于SDT的智慧变电站站端遥测数据修正系统

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电子设计工程 2024年第19期32卷 38-41,46页

作者：刘德亮郑欢蓝映彬中国南方电网有限责任公司广东广州510663 武汉大学湖北武汉430072

针对海量变电站遥测数据堆积,导致数据修正误差较大的问题,设计基于结构化数据传送(Structured Data Transfer,SDT)的智慧变电站站端遥测数据修正系统。通过遥测数据前端处理模块并行处理转换数据。利用遥测数据判读模块,结合专家测试... 详细信息

针对海量变电站遥测数据堆积,导致数据修正误差较大的问题,设计基于结构化数据传送(Structured Data Transfer,SDT)的智慧变电站站端遥测数据修正系统。通过遥测数据前端处理模块并行处理转换数据。利用遥测数据判读模块,结合专家测试库知识判读反馈数据。根据实际数据中显著数据污染率,确定待修正遥测数据。结合异常数据决策规则,应用基于SDT数据修正技术压缩海量遥测数据,避免待修正遥测数据大量堆积。设定SDT数据压缩强制记录限度,将最大误差序列作为系统输入量,构建修正函数,获取站端遥测数据修正结果。测试结果表明,该系统修正的视在功率数据和电流与理想数据存在最大为0.2 MVA和8 A的误差,能够为智慧变电站稳定运行提供可靠数据。

关键词：结构化数据传送智慧变电站站端遥测数据数据修正误差序列

Calculation of the CO2 Degassing during Contact Metamorphism and Its Geological Significance:The Model and Example from the Shuanshan Area of the South Tan-Lu Fault Belt

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Acta Geologica Sinica(English Edition) 2008年第3期82卷 562-576页

作者： YANG Xiaoyong liu deliang CHEN Yongjian DAI Jinxing CAS Key Laboratory of Crust-Mantle Materials and Environments School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China State Key Laboratory of Continental Dynamics Department of Geology Northwest University Xi＇an 710069 China The Institute of Research and Exploration for Oil and Natural Gas China ChiefOil and Natural Gas Corporation Beijing 100083 China

The paper studies CO2 degassing and controlling factors under the condition of contact metamorphism in the Shuangshan area, southern Tan-Lu fault belt and the method of calculating the amount of CO2 degassing. The results show that the amount of CO2 degassing is controlled by the characteristics of the country rocks, including the thermal conductivity, penetrability, porosity and connectivity. Compositions, size and depth of intrusive rock also have an important influence on CO2 degassing, i.e., they generated numerous cracks in the country rocks, and thus allowed the easy flow and accumulation of fluids. The amount of CO2 flux in contact metamorphism is calculated quantitatively based on the metamorphic reaction and time-integrated fluid flux. The value （0.729- 2.446×10^4 mol/cm^2） of CO2 flux suggests that CO2 was provided mainly by the contact metamorphic reaction. The generation and releasing of CO2 are positively correlated with the degree of metamorphism, and XCO2 in fluids gradually increases from dolomite zone to calcite zone, but in the zone of grossular, fluid flux is the largest and XCO2 sharply decreases due to involvement of magmatic water. This study presents evidence that a large amount of industrial-scale CO2 can be produced during contact metamorphism. On the basis of theoretical and practical studies, a cone model has been proposed to response CO2 degassing for the contact metamorphism, and it can be used to explore CO2 accumulations beyond the oil-gas basins. This model can also be applied to the study of inorganic genesis of CO2 accumulations.

关键词： Contact metamorphism CO2 degassing CO2 accumulations Tan-Lu fault belt

基于声发射和GA-BP神经网络的铣削SiCp/Al表面粗糙度预测

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软件工程 2024年第4期27卷 6-12页

作者：蒋厚伟陈宗玉刘德亮柳苏洋上海理工大学上海200082 北京兴华机械厂有限公司北京102600

为满足航天航空、电子封装、光学精密仪器等领域对工件加工质量的高要求,针对提高中高体积分数铝基碳化硅复合材料(SiCp/Al)铣削表面粗糙度的声发射智能在线监测精度的问题,通过小波包技术对铣削声发射信号进行分解,对分解后的特征值与... 详细信息

为满足航天航空、电子封装、光学精密仪器等领域对工件加工质量的高要求,针对提高中高体积分数铝基碳化硅复合材料(SiCp/Al)铣削表面粗糙度的声发射智能在线监测精度的问题,通过小波包技术对铣削声发射信号进行分解,对分解后的特征值与表面粗糙度进行相关性分析,确定了最相关频段为375~406.25 kHz,筛选出相关特征矩阵,并利用GA-BP(Genetic Algorithm-Back Propagation)神经网络进行训练。研究结果表明,该方法能够实现对45%SiCp/Al铣削表面粗糙度的较小预测误差,通过成功构建的声发射预测模型,将平均预测误差控制在0.050 4左右,相比未经特征提取的BP神经网络模型,该方法的平均预测误差减小了0.072 8,为工程实践提供了可行且有效的方法。

关键词： SiCp/Al 铣削声发射小波包分解相关性分析 GA-BP神经网络

Rock Deformation,Component Migration and 18O/16O Variations during Mylonitization in the Southern Tan-Lu Fault Belt

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Acta Geologica Sinica(English Edition) 2007年第2期81卷 297-311页

作者： YANG Xiaoyong liu deliang FENG Min YU Qingni WANG Kuiren CAS Key Laboratory of Crust-Mantle Materials and Environments School of Earth and Space Sciences University of Science and Technology of China Hefei Anhui 230026 CAS Key Laboratory of Isotope Geochronology and Geochemistry Guangzhou Institute of Geochemistry Guangzhou Guangdong 510640

This paper discusses the relationship between the volume loss, fluid flow and component variations in the ductile shear zone of the southern Tan-Lu fault belt. The results show that there is a large amount of fluids flowing through the shear zone during mylonitization, accompanied with the loss of volume of rocks and variations of elements and oxygen isotopes. The calculated temperature for mylonitization in different mylonites ranges from 446 to 484℃, corresponding to that of 475 to 500℃ for the wall rocks. The condition of differential stress during mylonization has been obtained between 99 and 210 MPa, whereas the differential stress in the wall rock gneiss is 70-78 MPa. The mylonites are enriched by factors of 1.32-1.87 in elements such as TiO2, P2O5, MnO, Y, Zr and V and depleted in SiO2, Na2O, K2O, Al203, Sr, Rb and light REEs compared to their protolith gneiss. The immobile element enrichments are attributed to enrichments in residual phases such as ilmentite, zircon, apatite and epidote in mylonites and are interpreted as due to volume losses from 15% to 60% in the ductile shear zone. The largest amount of SiO2 loss is 35.76 g/100 g in the ductile shear zone, which shows the fluid infiltration. Modeling calculated results of the fluid/rock ratio for the ductile shear zone range from 196 to 1192 by assuming different degrees of fluid saturation. Oxygen isotope changes of quartz and feldspar and the calculated fluid are corresponding to the variations of differential flow stress in the ductile shear zone. With increasing differential flow stress, the mylonites show a slight decrease of δ^18O in quartz, K-feldspar and fluid.

关键词： mylonitization ductile shear zone component migration oxygen isotopes southern Tan- Lu fault belt