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Associations of Daytime Napping with Incident Cardiovascular Diseases and Hypertension in Chinese Adults:A Nationwide Cohort Study

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Biomedical and Environmental Sciences 2022年第1期35卷 22-34页

作者： WANG Lu WANG Ke liu lin jiong ZHANG Yuan Yuan SHU Hai Nan WANG Kai ZHOU Pei Xuan ZHANG Yun Quan Department of Nursing Medical CollegeWuhan University of Science and TechnologyWuhan 430065HubeiChina Department of Epidemiology and Biostatistics School of Public HealthWuhan University of Science and TechnologyWuhan 430065HubeiChina Hubei Province Key Laboratory of Occupational Hazard Identification and Control Wuhan University of Science and TechnologyWuhan 430065HubeiChina

Objective This study aimed to examine the associations of daytime napping with incident risks of cardiovascular diseases(CVDs)and hypertension(HTN).Methods Data for napping and CVD outcomes in 25 provinces were collected from baseline(2010)and three waves of follow-up(2012-2017)investigations of the China Family Panel *** frailty models with random intercepts for the surveyed provinces were used to assess the longitudinal effects of daytime napping on CVD and *** Compared with non-nappers,30+min nappers had higher risks of CVD and HTN,while no significant associations were observed among<30 min *** risks among 30-to<60-min nappers increased by 22%[hazard ratio(HR)1.22,95% confidence interval(CI)1.08-1.39]for CVD and 21%(1.21,1.04-1.41)for HTN,respectively,with corresponding HRs of CVD and HTN of 1.27(1.09-1.47)and 1.38(1.16-1.65)among≥60 min ***-associated CVD risks varied by subgroups,with stronger associations in participants with lower body mass index(<24 kg/m^(2)),physically inactive persons,smokers,and participants with longer nighttime sleep(≥7 h/night).Significant effects of daytime napping were observed on rural and northern residents only,highlighting great regional variations in CVD risks associated with napping *** This cohort study revealed strong evidence that long daytime napping(≥30 min)is associated with an increased incidence of cardiovascular events.

关键词： Daytime napping Cardiovascular disease Hypertension Adults Sleep duration

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Floor heave mechanism for gob-side entry retaining with concrete blocks and control method:A case study

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Underground Space 2024年第2期15卷 244-259页

作者： jiong Wang Peng liu Manchao He Guangyuan Yu Huanzhi Tian State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of Mechanics and Civil Engineering China University of Mining and Technology(Beijing)Beijing 100083China College of Mining Engineering North China University of Science and TechnologyTangshan 063210China

The issue of significant floor heave deformation in gob-side entry retaining has long been a challenging problem in the context of longwall *** paper studies the floor heave failure mechanism and control method for gob-side entry retaining with concrete blocks in Guizhou Faer Coal Mine in *** on Rankine’s earth pressure theory,the effective shear stress equation for the plastic slip of roadway floor is *** deformation mechanism of floor heave in a retaining roadway with a block wall is revealed in this *** new comprehensive control method is proposed,encompassing roof pre-splitting blasting for pressure relief,reinforcing cables for roof control,double directions control bolts for concrete block,and pliability cushion yielding ***3D numerical calculation model is established,which shows that the new method can effectively reduce the average vertical stress peak value of the entity coal floor by 34.6%and significantly reduce the pressure source causing the roadway floor ***,a multi-parameter real-time online monitoring system for mine pressure was designed,and field tests were carried *** results show that the maximum value of roadway floor heave under the new method is 163 mm,reduced by 66.9%,and the roadway floor heave is effectively *** research findings offer a fresh perspective and new ideas for controlling floor heave in mining operations.

关键词： Gob-side entry retaining Floor heave mechanism Plastic slip Control methods Mine pressure monitoring

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Mechanical behavior of 2G NPR bolt anchored rock samples under static disturbance loading

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Journal of Mountain Science 2024年第7期21卷 2494-2516页

作者： WANG jiong JIANG Jian WANG Siyu CHANG Yiwen liu Peng HE Manchao CHENG Shuang State Key Laboratory for Tunnel Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of Mechanics and Civil Engineering China University of Mining and Technology(Beijing)Beijing 100083China

The deep mining of coal resources is accompanied by severe environmental challenges and various potential engineering *** implementation of NPR(negative Poisson's ratio)bolts are capable of controlling large deformations in the surrounding rock *** paper focuses on studying the mechanical properties of the NPR bolt under static disturbance *** deep nonlinear mechanical experimental system was used to study the mechanical behavior of rock samples with different anchored types(unanchored/PR anchored/2G NPR anchored)under static disturbance *** whole process of rock samples was taken by high-speed camera to obtain the real-time failure characteristics under static disturbance *** the same time,the acoustic emission signal was collected to obtain the key characteristic parameters of acoustic emission such as acoustic emission count,energy,and *** deformation at the failure of the samples was calculated and analyzed by digital speckle *** findings indicate that the failure mode of rock is influenced by different types of *** peak failure strength of 2G NPR bolt anchored rock samples exhibits an increase of 6.5%when compared to the unanchored rock *** cumulative count and cumulative energy of acoustic emission exhibit a decrease of 62.16%and 62.90%,*** maximum deformation of bearing capacity exhibits an increase of 59.27%,while the failure time demonstrates a delay of 42.86%.The peak failure strength of the 2G NPR bolt anchored ones under static disturbance load exhibits an increase of 5.94%when compared to the rock anchored by PR(Poisson's ratio)*** cumulative count and cumulative energy of acoustic emission exhibit a decrease of 47.16%and 43.86%,*** maximum deformation of the bearing capacity exhibits an increase of 50.43%,and the failure time demonstrates a delay of 32%.After anchoring by 2G NPR bolt,anchoring support effectively reduces the risk of damage caused by s

关键词： Anchored rock samples Static disturbance load Acoustic emission characteristics Digital speckle Negative Poisson's ratio

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Broadband angular spectrum analog processors based on all-dielectric metasurfaces

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Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 188-190页

作者： lin Deng Yongmin liu Department of Electrical and Computer Engineering Northeastern UniversityBoston 02115USA Department of Mechanical and Industrial Engineering Northeastern UniversityBoston 02115USA

Digital signal processors are extensively used to execute mathematical operations and advanced computational tasks on digital ***,they suffer from several inherent limitations,including low speed,high energy consumption,and large memory requirements,because of the hardware bottleneck and the imperative conversion between digital and analogue signals.

关键词： dielectric spectrum hardware

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Field survey and analysis on near-fault severely damaged high-speed railway bridge in 2022 M6.9 Menyuan earthquake

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Earthquake Engineering and Engineering Vibration 2024年第4期23卷 1043-1055页

作者： lin Xuchuan liu Fuxiang Shan Wenchen Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin 150080China Key Laboratory of Earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin 150080China Institute of Smart City and Intelligent Transportation Southwest Jiaotong UniversityChengdu610000China

The 2022 M6.9 Menyuan earthquake caused severe damage to a high-speed railway bridge,which was designed for high-speed trains running at speeds of above 250 km/h and is located right next to the *** of this type have been widely used for rapidly constructing the high-speed railway network,but few bridges have been tested by near-fault devastating *** potential severe impact of the earthquake on the high-speed railway is not only the safety of the infrastructure,trains and passengers,but also economic loss due to interrupted railway ***,a field survey was carried out immediately after the earthquake to collect time-sensitive *** damage to the bridge was carefully investigated,and quantitative analyses were conducted to better understand the mechanism of the bridge *** was found that seismic action perpendicular to the bridge’s longitudinal direction caused severe damage to the girders and rails,while none of the piers showed obvious deformation or *** maximum values of transverse displacement,out-of-plane rotation and twisting angle of girders reached 212.6 cm,3.1 degrees and 19.9 degrees,respectively,causing severe damage to the bearing supports and anti-seismic retaining *** observations provide a basis for improving the seismic design of high-speed railway bridges located in near-fault areas.

关键词： Menyuan earthquake field survey high-speed railway bridge near fault seismic damage

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Flexible Crystal Heterojunctions of Low-Dimensional Organic Metal Halides Enabling Color-Tunable Space-Resolved Optical Waveguides

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Research 2024年第3期6卷 293-304页

作者： Yuhang lin Shuya liu Dongpeng Yan Beijing Key Laboratory of Energy Conversion and Storage Materials and Key Laboratory of RadiopharmaceuticalsMinistry of EducationCollege of ChemistryBeijing Normal UniversityBeijing 100875China.

Molecular luminescent materials with optical waveguide have wide application prospects in light-emitting diodes, sensors, and logic gates. However, the majority of traditional optical waveguide systems are based on brittle molecular crystals, which limited the fabrication, transportation, storage, and adaptation of flexible devices under diverse application situations. To date, the design and synthesis of photofunctional materials with high flexibility, novel optical waveguide, and multi-port color-tunable emission in the same solid-state system remain an open challenge. Here, we have constructed new types of zero-dimensional organic metal halides (Au-4-dimethylaminopyridine [DMAP] and In-DMAP) with a rarely high elasticity and rather low loss coefficients for optical waveguide. Theoretical calculations on the intermolecular interactions showed that the high elasticity of 2 molecular crystalline materials was original from their herringbone structure and slip plane. Based on one-dimensional flexible microrods of 2 crystals and the 2-dimensional microplate of the Mn-DMAP, heterojunctions with multi-color and space-resolved optical waveguides have been fabricated. The formation mechanism of heterojunctions is based on the surface selective growth on account of the low lattice mismatch ratio between contacting crystal planes. Therefore, this work describes the first attempt to the design of metal-halide-based crystal heterojunctions with high flexibility and optical waveguide, expanding the prospects of traditional luminescent materials for smart optical devices, such as logic gates and multiplexers.

关键词： waveguide Crystal elasticity

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Improved catalytic performance of CO_(2) electrochemical reduction reaction towards ethanol on chlorine-modified Cu-based electrocatalyst

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Nano Research 2024年第5期17卷 3761-3768页

作者： Yifan liu Hehua Tang Yitian Zhou Bo-lin lin School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China

Effective electrochemical conversion of CO_(2) to value-added liquid multi-carbon products driven by renewable energy is a promising approach to alleviate excessive CO_(2) emission and achieve large-scale renewable energy ***,the selectivity and catalytic activity towards liquid multi-carbon products of CO_(2) electroreduction reaction are still unsatisfactory due to the sluggish C-C coupling process and the formation of complex oxygen-containing ***,designing and fabricating highly effective electrocatalysts is crucial for practical applications in this ***,we developed Cl-modified Cu catalyst(Cu-Cl)for efficient electrochemical reduction of CO_(2) to *** optimal Faradaic efficiency and partial current density of ethanol on the Cu-Cl sample reached 26.2%and 343.2 mA·cm^(-2) at-0.74 V(*** hydrogen electrode(RHE)),which were 1.66 and 1.76 times higher than those of the catalyst without Cl decoration,outperforming those in most previously reported *** functional theory(DFT)calculations revealed that the Cl-modified Cu surface suppressed the parasitic hydrogen evolution reaction(HER)and reduced the energy barrier for the C-C coupling process,making the formation of key intermediates favorable for ethanol ***,the decoration of Cl on the Cu surface facilitated ethanol formation.

关键词： CO_(2)electrochemical reduction halogen chlorine Cu-based catalysts ethanol multi-carbon products

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Integrin β5 subunit regulates hyperglycemia-induced vascular endothelial cell apoptosis through FoxO1-mediated macroautophagy

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Chinese Medical Journal 2024年第5期137卷 565-576页

作者： Xuze lin Sizhuang Huang Side Gao Jinxing liu jiong Tang Mengyue Yu Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100037China Department of Cardiology Fuwai Yunnan Cardiovascular HospitalKunmingYunnan 650000China

Background:Hyperglycemia frequently induces apoptosis in endothelial cells and ultimately contributes to microvascular dysfunction in patients with diabetes mellitus(DM).Previous research reported that the expression of integrins as well as their ligands was elevated in the diseased vessels of DM ***,the association between integrins and hyperglycemia-induced cell death is still *** research was designed to investigate the role played by integrin subunit β5(ITGB5)in hyperglycemia-induced endothelial cell ***:We used leptin receptor knockout(Lepr-KO)(db/db)mice as spontaneous diabetes animal *** deletion of ITGB5 in endothelial cell was achieved by injecting vascular targeted adeno-associated virus via tail ***,we also applied small interfering RNA in vitro to study the mechanism of ITGB5 in regulating high glucose-induced cell ***:ITGB5 and its ligand,fibronectin,were both upregulated after exposure to high glucose in vivo and in ***5 knockdown alleviated hyperglycemia-induced vascular endothelial cell apoptosis and microvascular rarefaction in *** vitro analysis revealed that knockdown of either ITGB5 or fibronectin ameliorated high glucose-induced apoptosis in human umbilical vascular endothelial cells(HUVECs).In addition,knockdown of ITGB5 inhibited fibronectin-induced HUVEC apoptosis,which indicated that the fibronectin-ITGB5 interaction participated in high glucose-induced endothelial cell *** using RNA-sequencing technology and bioinformatic analysis,we identified Forkhead Box Protein O1(FoxO1)as an important downstream target regulated by ***,we demonstrated that the excessive macroautophagy induced by high glucose can contribute to HUVEC apoptosis,which was regulated by the ITGB5-FoxO1 ***:The study revealed that high glucose-induced endothelial cell apoptosis was positively regulated by ITGB5,which suggested that ITGB5 could potentially be used

关键词： Endothelial cell apoptosis Integrin Autophagy Diabetes

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CFD-DEM simulation of fluorination reaction in fluidized beds with local grid and time refinement method

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Particuology 2024年第1期84卷 145-157页

作者： Mofan Qiu lin Jiang Rongzhen liu Yaping Tang Malin liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy TechnologyTsinghua UniversityBeijing100084China

The gas-solid reaction process with wide particle size distribution is extensively used in the chemical engineering field,especially the particle reacts with the gas gradually,such as fluorination reactions in fluidized *** the computational fluid dynamics-discrete element method(CFD-DEM)is used for the coupling simulation of multiphase and polydisperse particle reaction system,the grid size directly affects the accuracy of flow field information and simulation of chemical ***,particle calculation time step will directly affect the efficiency of coupling *** this work,a local grid and time step refinement method is proposed to simulate multiphase and polydisperse particle fluid-ization reaction *** this method,the refined DEM grids are automatically generated in the computational domain around the fine particles,and the detailed fluid phase information is obtained with the interpolation *** the two-phase coupling process,particles are divided into different groups based on physical properties,each group has its own independent time *** multistage conical-cylindrical spouted bed is proposed for the fluorination reaction process;the operating gas ve-locity range of the polydisperse particle system is extended by the new design while the particle size distribution changes with the gas-solid reaction *** is demonstrated that the local grid and time step refinement method can improve the accuracy and efficiency of the traditional CFD-DEM method in the reaction process simulation,which describes a polydisperse particle system with wide particle size *** at improving the simulation accuracy and efficiency,this paper will be helpful for simulating the particle reaction process in the gas-solid fluidized bed and beneficial for the development of the CFD-DEM method.

关键词： CFD-DEM Polydisperse particle Two-phase flow Fluidized bed

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CFD-DEM simulation of high density particles fluidization behaviors in 3D conical spouted beds

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Particuology 2024年第5期88卷 266-281页

作者： lin Jiang Mofan Qiu Rongzheng liu Bing liu Youlin Shao Malin liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy TechnologyTsinghua UniversityBeijing 100084China

The spouted bed has been used in the coating process of high-density nuclear fuel *** particle fluidization behaviors in pseudo-2D and 3D spouted beds were simulated and *** effects of four independent variables(cone angle,particle density,inlet gas velocity,and particle loading)on particle fluidization behaviors in the 3D spouted bed were investigated *** cone angle effect on fluidization mechanism was studied quantitatively first time.A new fluidization quality index was proposed based on the particle entrainment principle,and an extreme value was obtained when the cone angle was 60°,considered to be the optimum value for the 3D conical spouted *** was indicated the gas–solid contact efficiency can be kept up if the gas velocity was proportional to ρ_(p)^(0.65) and N_(p)^(0.78) when the particle density or loading was *** results will be useful for geometry and operation parameters design of the 3D conical spouted bed and helpful for developing the fluidization mechanism of high-density particles.

关键词： Spouted bed High-density particle CFD-DEM Fluidization quality index Particle loading

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