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Efficacy of needling acupoints of Guanyuan(CV4), Sanyinjiao(SP6), Zusanli(ST36), Pishu(BL20), Shenshu(BL23), Zigong(EX-CA1) on expression of p38 mitogen-activated protein kinase in ovarian tissue in rats with premature ovarian failure induced by cyclophosp

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Journal of Traditional Chinese Medicine 2021年第6期41卷 953-958页

作者： WANG Shengchun JIANG Yiming qiu lirong SU Meng Department of Acupuncture Physiotherapy Rehabilitation Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China Specialty of acupuncture and massage Traditional Chinese Medicine of Shandong UniversityJinan 250014China

OBJECTIVE:To investigate the efficacy of needling acupoins of Guanyuan(CV4),Sanyinjiao(SP6),Zusanli(ST36),Pishu(BL20),Shenshu(BL23),Zigong(EX-CA1)on the expression of p38 mitogen-activated protein kinase(p38MAPK)in ovarian tissue in rats with premature ovarian failure induced by cyclophosphamide,and to study the underlying ***:Forty specific pathogen free female Sprague-Dawley rats were randomly divided into the blank group,the model group,the acupuncture group,the Western Medicine group and the Western Medicine combined with acupuncture *** the blank group,the rest of the rats were given with cyclophosphamide for 14 d to establish premature ovarian failure *** intervention was conducted in the blank group and model group;the acupuncture group was given with acupuncture daily;the Western Medicine group was given with estradiol valerate(0.09 mg/kg)by intragastrical gavage daily;the combination group was given with acupuncture combined with estradiol valerate(0.09 mg/kg)*** group was intervened in continuously for 14 *** the last treatment,the levels of estradiol(E2),follicle stimulating hormone(FSH)and luteinizing hormone(LH)were detected by enzyme-linked immunosorbent assay,then the ovarian tissue was *** blot was used to detect the expression of p38 MAPK ***:Compared with the blank group,E2 in the serum of rats in the model group was significantly decreased(P<0.05),FSH and LH were significantly increased(P<0.05),and the expression of p38 MAPK protein in the ovarian tissue of the rats was significantly increased(P<0.05).Compared with the model group,E2 in the serum of the acupuncture group,Western Medicine group and the combination group were significantly increased(P<0.05),FSH and LH levels were significantly decreased(P<0.05),and the expression of p38MAPK protein in the ovarian tissue of the rats was significantly decreased(P<0.05).However,there was no statistically significant difference between the

关键词： acupuncture premature ovarian insufficiency p38 mitogen-activated protein kinases signal transduction

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A High-Resolution Measurement Method for Inner and Outer 3D Surface Profiles of Laser Fusion Targets Using a Laser Differential Confocal–Atomic Force Probe Technique

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Engineering 2024年第10期41卷 51-60页

作者： Weiqian Zhao Zihao Liu lirong qiu MIIT Key Laboratory of Complex-Field Intelligent Exploration School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China

The high-resolution and nondestructive co-reference measurement of the inner and outer threedimensional(3D)surface profiles of laser fusion targets is difficult to *** this study,we propose a laser differential confocal(LDC)–atomic force probe(AFP)method to measure the inner and outer 3D surface profiles of laser fusion targets at a high *** method utilizes the LDC method to detect the deflection of the AFP and exploits the high spatial resolution of the AFP to enhance the spatial resolution of the outer profile *** and co-reference measurements of the inner profile of a target were achieved using the tomographic characteristics of the LDC ***,by combining multiple repositionings of the target using a horizontal slewing shaft,the inner and outer 3D surface profiles of the target were obtained,along with a power spectrum assessment of the entire *** experimental results revealed that the respective axial and lateral resolutions of the outer profile measurement were 0.5 and 1.3 nm,while the respective axial and lateral resolutions of the inner profile measurement were 2.0 nm and approximately 400.0 *** repeatabilities of the rootmean-square deviation measurements for the outer and inner profiles of the target were 2.6 and 2.4 nm,*** believe our study provides a promising method for the high-resolution and nondestructive co-reference measurement of the inner and outer 3D profiles of laser fusion targets.

关键词： Laser fusion targets Laser differential confocal-atomic force probe High-resolution Nondestructive Co-reference

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A high-precision multi-dimensional microspectroscopic technique for morphological and properties analysis of cancer cell

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Light(Science & Applications) 2023年第6期12卷 1117-1126页

作者： lirong qiu Yunhao Su Ke-Mi Xu Han Cui Dezhi Zheng Yuanmin Zhu Lin Li Fang Li Weiqian Zhao MIIT Key Laboratory of Complex-field Intelligent Exploration School of Optics and PhotonicsBeijing Institute of Technology100081 BeijingChina Department of Gastroenterology Aerospace Central HospitalPeking University Aerospace School of Clinical Medicine100081 BeijingChina Department of Pathology Aerospace Central HospitalPeking University Aerospace School of Clinical Medicine100081 BeijingChina

Raman and Brillouin scattering are sensitive approaches to detect chemical composition and mechanical elasticity pathology of cells in cancer development and their medical treatment *** application is,however,suffering from the lack of ability to synchronously acquire the scattering signals following three-dimensional(3D)cell morphology with reasonable spatial resolution and signal-to-noise ***,we propose a divided-aperture laser differential confocal 3D Geometry-Raman-Brillouin microscopic detection technology,by which reflection,Raman,and Brillouin scattering signals are simultaneously in situ collected in real time with an axial focusing accuracy up to 1 nm,in the height range of 200μ*** divided aperture improves the anti-noise capability of the system,and the noise influence depth of Raman detection reduces by 35.4%,and the Brillouin extinction ratio increases by 22 dB.A high-precision multichannel microspectroscopic system containing these functions is developed,which is utilized to study gastric cancer *** a result,a 25%reduction of collagen concentration,42%increase of DNA substances,17%and 9%decrease in viscosity and elasticity are finely resolved from the 3D *** findings indicate that our system can be a powerful tool to study cancer development new therapies at the sub-cell level.

关键词： elasticity dimensional spectroscopic

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Large dynamic range Shack-Hartmann wavefront sensor based on adaptive spot matching

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Light(Advanced Manufacturing) 2024年第1期5卷 40-49页

作者： Jiamiao Yang Jichong Zhou lirong qiu Rongjun Shao Linxian Liu Qiaozhi He School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Institute of Marine Equipment Shanghai Jiao Tong UniversityShanghai 200240China Beijing Key Lab for Precision Optoelectronic Measurement Instrument and Technology School of OptoelectronicsBeijing Institute of TechnologyBeijing 100081China School of Automation and Software Engineering Shanxi UniversityTaiyuan 030006China

The Shack-Hartmann wavefront sensor(SHWS)is widely used for high-speed,precise,and stable wavefront ***,conventional SHWSs encounter a limitation in that the focused spot from each microlens is restricted to a single microlens,leading to a limited dynamic ***,we propose an adaptive spot matching(ASM)-based SHWS to extend the dynamic *** approach involves seeking an incident wavefront that best matches the detected spot distribution by employing a Hausdorff-distance-based nearest-distance matching *** ASM-SHWS enables comprehensive spot matching across the entire imaging plane without requiring initial spot ***,due to its global matching capability,ASM-SHWS can maintain its capacity even if a portion of the spots are *** showed that the ASM-SHWS could measure a high-curvature spherical wavefront with a local slope of 204.97 mrad,despite a 12.5%absence of *** value exceeds that of the conventional SHWS by a factor of 14.81.

关键词： Wavefront sensing Large dynamic range Shack-Hartmann sensor

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Laser self-mixing interferometer with scalable fringe precision based on phase multiplication algorithm

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Optoelectronics Letters 2021年第11期17卷 665-668页

作者： WANG Xiulin XIONG Yanbin XU Huizhen qiu lirong LI Zhen HUANG Wencai Department of Physics Jimei UniversityXiamen 361021China Department of Electronics Engineering Xiamen UniversityXiamen 361005China

In this paper,we present a phase multiplication algorithm(PMA)to obtain scalable fringe precision in laser self-mixing interferometer under a weak feedback *** by applying the double angle formula on the self-mixing signal multiple times,the continuously improved fringe precision will be *** analysis shows that the precision of the fringe could be improved toλ/2^(n+1).The validity of the proposed method is demonstrated by means of simulated SMI signals and confirmed by experiments under different amplitudes.A fringe precision ofλ/128 at a sampling rate of 500 k S/s has been achieved after doing 6 th the ***,an amplitude of 50 nm has been proved to be measurable and the absolute error is 3.07 nm,which is within the theoretical error *** proposed method for vibration measurement has the advantage of high accuracy and reliable without adding any additional optical elements in the optical path,thus it will play an important role in nanoscale measurement field.

关键词： Laser self-mixing interferometer with scalable fringe precision based on phase multiplication algorithm

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Synchronous nanoscale topographic and chemical mapping by differential-confocal controlled Raman microscopy

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Photonics Research 2020年第9期8卷 1441-1447页

作者： HAN CUI YUN WANG lirong qiu SHUCHENG LI JONATHAN M.COOPER AND WEIQIAN ZHAO Key Laboratory for Precision Optoelectronic Measurement Instrument and Technology School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China Division of Biomedical Engineering James Watt School of EngineeringUniversity of GlasgowGlasgow G128LTUK

Confocal Raman microscopy is currently used for label-free optical sensing and imaging within the biological,engineering,and physical sciences as well as in ***,currently these methods have limitations,including their low spatial resolution and poor focus stability,that restrict the breadth of new *** paper now introduces differential-confocal controlled Raman microscopy as a technique that fuses differential confocal microscopy and Raman spectroscopy,enabling the point-to-point collection of three-dimensional nanoscale topographic information with the simultaneous reconstruction of corresponding chemical *** microscope collects the scattered Raman light together with the Rayleigh light,both as Rayleigh scattered and reflected light(these are normally filtered out in conventional confocal Raman systems).Inherent in the design of the instrument is a significant improvement in the axial focusing resolution of topographical features in the image(to^1 nm),which,when coupled with super-resolution image restoration,gives a lateral resolution of 220 *** using differential confocal imaging for controlling the Raman imaging,the system presents a significant enhancement of the focusing and measurement accuracy,precision,and stability(with an antidrift capability),mitigating against both thermal and vibrational *** also demonstrate an improved scan speed,arising as a consequence of the nonaxial scanning mode.

关键词： scattered chemical stability

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面对网络建设的新发展

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中国有线电视 2001年第2期 40-41页

作者：裘礼荣信息产业部电子五十四所 050081

1　宽带网建设的发展过程　　早期的电信网络是通过E1/T1、帧中继、DDT等连接来实现文件传输、电子邮件等业务，后来出现E3/T3、快速以太网等技术可实现图像的传输，但要传送多媒体信息就显得带宽不足。21世纪是知识经济时代，是知识化... 详细信息

1　宽带网建设的发展过程　　早期的电信网络是通过E1/T1、帧中继、DDT等连接来实现文件传输、电子邮件等业务，后来出现E3/T3、快速以太网等技术可实现图像的传输，但要传送多媒体信息就显得带宽不足。21世纪是知识经济时代，是知识化、信息化、网络化的时代。通过各种互联网的大量信息、电子商务网站的建立、政府上网、企业上网……，这些数据传输的业务量将呈几何级数增长，而基于窄带的电信网络，将难以满足其要求。因此，建设信息高速公路，建设大容量、宽频带、高速率的数据网势在必行。　　我国宽带网建设主要有3种方式：IP OVER SDH，IP OVER ATM，IP OVER DWDM。　　我国前几年已在全国各地陆续建立了若干光纤同步网系统(SONET)，后来又逐步建起了若干异步传输模式(ATM)的宽带网。

关键词：网络建设电信网宽带网 IP网

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Ku频段SCPC数字压缩式卫星广播电视节目的接收

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电视技术 1999年第11期23卷 42-44页

作者：裘礼荣河北电子工业部五十四所

1 Ku频段的特点及应用前景在东经100.5°的亚洲卫星2号(ASIASAT-2)上,用一个转发器(K5)同时播发了北京市、山西省、河北省及天津市数字压缩卫星广播电视节目.它分别由各省市的卫星发射站向赤道上空的同步卫星发送信号,因而采用的是单路... 详细信息

1 Ku频段的特点及应用前景在东经100.5°的亚洲卫星2号(ASIASAT-2)上,用一个转发器(K5)同时播发了北京市、山西省、河北省及天津市数字压缩卫星广播电视节目.它分别由各省市的卫星发射站向赤道上空的同步卫星发送信号,因而采用的是单路单载波(SCPC)方式.其中:北京台下行工作频率为12 329 MHz;山西台下行工作频率为12 339 MHz;天津台下行工作频率为12 389 MHz;河北台下行工作频率为12 349 MHz.

关键词： SCPC 数字压缩式卫星电视接收卫星广播

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球面惯性元件激光共焦曲率半径测量系统

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中国惯性技术学报 2019年第2期27卷 266-271页

作者：邱丽荣王超峰赵维谦北京理工大学光电学院

针对球面惯性元件散射特性导致其曲率半径测量难度大、精度低的问题,研制了一套球面惯性元件激光共焦曲率半径测量系统。系统通过针孔滤波降低探测器接收散射光的比例来抑制散射光的影响,利用共焦回馈技术提高返回光探测强度,以适应低... 详细信息

针对球面惯性元件散射特性导致其曲率半径测量难度大、精度低的问题,研制了一套球面惯性元件激光共焦曲率半径测量系统。系统通过针孔滤波降低探测器接收散射光的比例来抑制散射光的影响,利用共焦回馈技术提高返回光探测强度,以适应低反射率球面惯性元件的探测。采用共焦轴向光强响应曲线的峰值点精确对应物镜焦点的特性,对被测元件的猫眼和共焦位置进行精密定位,通过激光干涉仪获取两点间距离,继而实现曲率半径的高精度测量。以半球型动压气体轴承作为实验对象进行了实验。理论分析和实验结果表明,系统相对扩展不确定度优于20×10^-6,提出的测量系统为具有散射特性的球面惯性元件曲率半径的高精度测量提供了技术途径。

关键词：激光共焦曲率半径测量球面惯性元件抗散射

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基于主体的语义Web服务自动组合研究

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计算机研究与发展 2007年第4期44卷 643-650页

作者：邱莉榕史忠植林芬常亮中国科学院计算技术研究所

语义Web服务要解决的一个主要问题就是如何实现服务组合自动化.主体技术因其智能性、自主性等特点在解决语义Web服务组合问题中具有较大优势.通过分析语义Web服务组合研究现状,分析主体、语义Web与Web服务的紧密关系,论证了基于主体的语... 详细信息

语义Web服务要解决的一个主要问题就是如何实现服务组合自动化.主体技术因其智能性、自主性等特点在解决语义Web服务组合问题中具有较大优势.通过分析语义Web服务组合研究现状,分析主体、语义Web与Web服务的紧密关系,论证了基于主体的语义Web服务的可行性并描述了基于多主体的Web服务组合平台架构.介绍了基于主体技术的语义Web服务组合技术,将服务组合看成是一个多主体环境下的规划问题,给出语义Web服务作为主体动作子类的形式化定义,并针对服务组合问题增加限定条件,定义服务之间的5种关系,试图从逻辑角度,以描述逻辑为基本工具,突出服务的动态性与交互性.最后利用主体的目标规划以及基于描述逻辑的有效推理,给出了服务的自动组合算法.

关键词：语义Web服务服务组合 AI规划动态描述逻辑主体

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