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Rare Metals 2008年第1期27卷 32-35页

作者： lin wei ma ruixin shao wei kang bo wu zhongliang Department of Nonferrous Metallurgy University of Science and Technology Beijing Beijing 100083 China

To obtain high transmittance and low resistivity ZnO transparent conductive thin films,a series of ZnO ceramic targets（ZnO：Al,ZnO：（Al,Dy）,ZnO：（Al,Gd）,ZnO：（Al,Zr）,ZnO：（Al,Nb）,and ZnO：（Al,W）） were fabricated and used to deposit thin films onto glass substrates by radio frequency（RF） magnetron sputtering.X-ray diffraction（XRD） analysis shows that the films are polycrystalline fitting well with hexagonal wurtzite structure and have a preferred orientation of the（002） *** transmittance of above 86% as well as the lowest resistivity of 8.43 × 10^-3 Ω·cm was obtained.

关键词： ZnO transparent conductive thin film RF magnetron sputtering optical properties electrical properties

Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in glioma U87 cells

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Neural Regeneration Research 2010年第17期5卷 1319-1323页

作者： Fei Zhong Xiangyuan wu Chunkui shao Qu lin Min Dong Jingyun Wen Xiaokun ma Li wei Department of Medical Oncology Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of Pathology Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

Studies have shown that tumor necrosis factor-related apoptosis-inducing ligand（TRAIL）exhibits strong induction of apoptosis in human glioma *** remains unclear whether the mitochondrion pathway,an important apoptosis signaling pathway,is involved in TRAIL-induced glioma cell *** the present study,in vitro cultured human glioma U87 cells were treated with human recombinant soluble *** of glioma U87 cells,mitochondrial transmembrane potential（Δψm）,cytoplasmic cytochrome c concentration and changes in caspase-3,-8 and-9 activity following human recombinant soluble TRAIL treatment were investigated to determine the mechanism of glioma U87 cell apoptosis induced by ***,blocking caspase-8resulted in TRAIL-induced mitochondrion pathway activation,suggesting that TRAIL,through activating caspase-8,initiated a series of mitochondrial events and resulted in apoptosis of glioma U87 cells.

关键词： tumor necrosis factor-related apoptosis-inducing ligand glioma apoptosis mitochondria neural regeneration

Acceptor Engineering Produces Ultrafast Nonradiative Decay in NIR-Ⅱ Aza-boDIPY Nanoparticles for Efficient Osteosarcoma Photothermal Therapy via Concurrent Apoptosis and Pyroptosis

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Research 2024年第1期2023卷 625-635页

作者： Zhenxiong Shi Hua Bai Jiaxing wu Xiaofei Miao Jia Gao Xianning Xu Yi Liu Jiamin Jiang Jiaqi Yang Jiaxin Zhang Tao shao bo Peng Huili ma Dan Zhu Guojing Chen Wenbo Hu lin Li wei Huang Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory for Organic Electronics and Information Displays&Institute of Advanced materials(IAM) Nanjing University of Posts&TelecommunicationsNanjing 210023China Key Laboratory of Flexible Electronics(KLOFE)and IAM Nanjing Tech UniversityNanjing 211800China Britton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Advanced Biomedical Imaging FacilityHuazhong University of Science and TechnologyWuhan 430074China Department of Orthopedics Xijing HospitalThe Fourth Military Medical UniversityXi’an 710032China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China

Small-molecule photothermal agents(PTAs)with intense second near-infrared(NIR-Ⅱ,1,000 to 1,700 nm)absorption and high photothermal conversion efficiencies(PCEs)are promising candidates for treating deep-seated tumors such as *** date,the development of small-molecule NIR-Ⅱ PTAs has largely relied on fabricating donor–acceptor–donor(D–A–D/D′)structures and limited success has been ***,through acceptor engineering,a donor–acceptor–acceptor(D–A–A′)-structured NIR-Ⅱ aza-boron-dipyrromethene(aza-boDIPY)PTA(SW8)was readily developed for the 1,064-nm laser-mediated phototheranostic treatment of *** the donor groups to acceptor groups produced remarkable red-shifts of absorption maximums from first near-infrared(NIR-Ⅰ)regions(~808 nm)to NIR-Ⅱ ones(~1,064 nm)for aza-boDIPYs(SW1 to SW8).Furthermore,SW8 self-assembled into nanoparticles(SW8@NPs)with intense NIR-Ⅱ absorption and an ultrahigh PCE(75%,1,064 nm).This ultrahigh PCE primarily originated from an additional nonradiative decay pathway,which showed a 100-fold enhanced decay rate compared to that shown by conventional pathways such as internal conversion and vibrational ***,SW8@NPs performed highly efficient 1,064-nm laser-mediated NIR-Ⅱ photothermal therapy of osteosarcoma via concurrent apoptosis and *** work not only illustrates a remote approach for treating deep-seated tumors with high spatiotemporal control but also provides a new strategy for building high-performance small-molecule NIR-Ⅱ PTAs.

关键词： donor boDIPY intense

Cotton ethylene response factor Gh ERF91 is involved in the defense against Verticillium dahliae

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Journal of Integrative Agriculture 2024年第10期23卷 3328-3342页

作者： Nurimanguli Aini Yuanlong wu Zhenyuan Pan Yizan ma Qiushuang An Guangling Shui Panxia shao Dingyi Yang Hairong lin Binghui Tang Xin wei Chunyuan You Longfu Zhu Dawei Zhang Zhongxu lin Xinhui Nie Key Laboratory of Oasis Eco-agriculture Xinjiang Production and Construction Group/Agricultural CollegeShihezi UniversityShihezi 832003China National Key Laboratory of Crop Genetic Improvement/College of Plant Sciences&Technology Huazhong AgriculturalUniversityWuhan 430070China Cotton Research Institute Shihezi Academy of Agricultural ScienceShihezi 832011China Institute of Economic Crops Xinjiang Academy of Agricultural SciencesUrumqi 830091China

Verticillium dahliae causes significant losses in cotton *** reveal the mechanism of the defense response to *** in cotton,transcriptomic analyses were performed using cotton cultivars M138(***-resistant)and P2(***-susceptible).The results revealed 11,076 and 6,640 differentially expressed genes(DEGs)in response to ***,*** weighted gene co-expression network analysis of 4,633 transcription factors(TFs)indicated a“MEblue”module containing 654 TFs that strongly correlate with resistance to *** these TFs,the ethylene response factor Ghi_A05G10166(GhERF91)was identified as a putative hub gene with a defense response against ***.A virus-induced gene silencing assay and exogenous application of ethephon showed that GhERF91 is activated by ethylene and positively regulates the response to *** exposure in *** study provides fundamental transcriptome data and a putative causal gene(GhERF91)associated with resistance to ***,as well as genetic resources for breeding ***-resistant cotton.

关键词： cotton Verticillium wilt RNA-sequencing GhERF91 virus-induced gene silencing

Resource enrichment combined with biomass removal maintains plant diversity and community stability in a long-term grazed grassland

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Journal of Plant Ecology 2020年第5期13卷 611-620页

作者： Feng-wei Xu Jian-Jun Li Li-Ji wu Xiao-Ming Lu Wen Xing Di-ma Chen Biao Zhu shao-Peng Wang lin Jiang Yong-Fei Bai State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China Collaborative Innovation Center of Jiangxi Typical Trees Cultivation and Utilization College of ForestryJiangxi Agricultural UniversityNanchang 330045China College of Ecology and Environmental Science Inner Mongolia Agricultural UniversityHohhot 010011China Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081China College of Biological and Pharmaceutical Sciences China Three Gorges UniversityYichang 443002China Department of Ecology College of Urban and Environmental Scienceand Key Laboratory for Earth Surface Processes of the Ministry of EducationPeking UniversityBeijing 100871China School of Biology Georgia Institute of TechnologyAtlantaGA 30332USA College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China

Aims Long-term heavy grazing reduces plant diversity and ecosystem function by intensifying nitrogen(N)and water *** contrast,the absence of biomass removal can cause species loss by elevating light competition and weakening community stability,which is exacerbated by N and water ***,how to maintain species diversity and community stability is still a huge challenge for sustainable management of worldwide *** We conducted a 4-year manipulated experiment in six long-term grazing blocks to explore combination of resource additions and biomass removal(increased water,N and light availability)on species richness and community stability in semiarid grasslands of Inner Mongolia,*** Findings In all blocks treated with the combination of resource additions and biomass removal,primary productivity increased and species richness and community stability were maintained over 4 years of *** both species and plant functional group(PFG)levels,the aboveground biomass of treated plants remained temporally stable in treatments with the combination of N and/or water addition and biomass *** maintenance of species richness was primarily caused by the biomass removal,which could increase the amount of light exposure for grasses under resource *** species asynchrony and stability of PFGs contributed to the high temporal stability observed in these *** results indicate that management practices of combined resource enrichment with biomass removal,such as grazing or mowing,could not only enhance primary productivity but also maintain plant species diversity,species asynchrony and community ***,as overgrazing-induced degradation and resource enrichment-induced biodiversity loss continue to be major problems worldwide,our findings have important implications for adaptive management in semiarid grasslands and beyond.

关键词： biomass removal resource addition species richness community stability plant functional groups(PFGs) species asynchrony

Tumor suppressor p53 functions as an essential antiviral molecule against Japanese encephalitis virus

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Journal of Genetics and Genomics 2016年第12期43卷 709-712页

作者： Xufang Deng Jianchao wei Zixue Shi Wenjun Yan Zhuanchang wu Donghua shao Beibei Li Ke Liu Xiaodu Wang Yafeng Qiu Zhiyong ma Shanghai Veterinary Research Institute Chinese Academy of Agricultural ScienceNo.518Ziyue RoadShanghai 200241China Forestry and Biotechnology School Zhejiang Agriculture and Forestry UniversityLin'anHangzhou 211300China

Japanese encephalitis virus （jEV） is a mosquito-borne virus of the family Flaviviridae. It is the causative agent of Japanese encephalitis with approximately 50,000 infection cases and 10,000 fatal cases annually in Asia （Erlanger et al., 2009）. Although liveattenuated JEV vaccine has been developed and used for human and pig vaccination, JE occurs epidemically or sporadically in some developing countries or even in vaccinated areas （Solomon, 2006）. Host resistance factors play an important role in the outcome of viral infection.

关键词： RNA Tumor suppressor p53 functions as an essential antiviral molecule against Japanese encephalitis virus PFU NC

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TiAlN硬质薄膜/涂层材料的研究进展

硬质合金 2008年第3期25卷 186-191页

作者：王目孔马瑞新林炜康勃吴中亮北京科技大学冶金与生态工程学院北京100083

概述了TiAlN硬质薄膜/涂层材料的基本性质、应用及制备技术的发展。介绍了国内外利用磁控溅射法(MS)、空心阴极离子镀(HCD)、多弧离子镀等镀膜工艺制备TiAlN硬质薄膜材料的最新研究进展。TiAlN薄膜应用于切削加工、航空、航天和模具中... 详细信息

概述了TiAlN硬质薄膜/涂层材料的基本性质、应用及制备技术的发展。介绍了国内外利用磁控溅射法(MS)、空心阴极离子镀(HCD)、多弧离子镀等镀膜工艺制备TiAlN硬质薄膜材料的最新研究进展。TiAlN薄膜应用于切削加工、航空、航天和模具中的优良性能。

关键词： TiAlN硬质薄膜制备方法性能应用

Single-channel vector magnetic information detection method based on diamond NV color center

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Chinese Physics B 2021年第8期30卷 275-281页

作者： Qin-Qin Wang Rui-Rong Wang Jin-Ping Liu shao-Zhuo lin Liang-wei wu Hao Guo Zhong-Hao Li Huan-Fei Wen Jun Tang Zong-Min ma Jun Liu Key Laboratory of Instrumentation Science and Dynamic Measurement School of Instrument and ElectronicsNorth University of ChinaTaiyuan 030051China

A method of detecting the single channel triaxial magnetic field information based on diamond nitrogen-vacancy(NV)color center is ***,the incident angle of the bias magnetic field which can achieve the equal frequency difference optically-detected magnetic resonance(ODMR)spectrum of diamond NV color center is calculated theoretically,and the triaxial magnetic information solution model is also ***,the microwave time-controlled circuit module is designed to generate equal timing and equal frequency difference microwave pulse signals in one *** with the optical detection magnetic resonance technology,the purpose of sequentially locking and detecting the four formant signals on one side of the diamond NV color center(m_(s)=-1 state signal)is achieved,and the vector magnetic field information detection is accomplished by combining the triaxial magnetic information solution *** system can obtain magnetic field detection in a range of 0 mT-0.82 *** system's magnetic noise sensitivity is 14.2 nT/Hz^(1/2),and the deviation angle errors of magnetic field detectionθ_(x) andθ_(y) are 1.3° and 8.2° respectively.

关键词： nitrogen-vacancy(NV)color center vector electron spin magnetic detection

Orthotopic liver transplantation with hepatopancreatoduodenectomy for hilar cholangiocarcinoma

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Chinese Medical Journal 2007年第3期120卷 251-253页

作者： HE Xiao-shun ZHANG shao ZHU Xiao-feng WANG Dong-ping ma Yi WANG Guo-dong JU wei-qiang wu lin-wei HUANG Jie-fu Organ Transplantation Center Ftrst Affiliated Hospital of Sun Yat-sen University Guangzhou 510080 China

Although the surgical treatment for hilar cholangiocarcinoma represents the only potentially curative option, local excision and major hepatectomyl have failed to produce a favorable survival figure over the last decade. This is partly due to local tumor recurrences within the resection margin, perineural sheaths infiltration, and the regional lymph nodes metastasis after the surgery. Recently; an extended bile duct resection combined with total hepatectomy, pancreatoduodenectomy, and orthotopic fiver transplantation （HPLTx） was proposed to eradicate the entire biliary tract without cutting off the hepatoduodenal ligament. The results demonstrated an increased rate of curative （Ro） resections from 29% to 93% by HPLTx, and a favour＇able 5-year survival rate. We report here on a patient with advanced fiver disease associated with hilar cholangiocareinoma, who was treated successfully by HPLTx.

关键词： cholangiocarcinoma liver transplantation pancreatoduodenectomy

Experience of Clinical management for Pregnant Women and Newborns with Novel Coronavirus Pneumonia in Tongji Hospital,China

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Current Medical Science 2020年第2期40卷 285-289页

作者： shao-shuai WANG Xuan ZHOU Xing-guang lin Yan-yan LIU Jian-li wu Lali Mwamaka Shariful Xiao-lin HU Zhi-bui RONG wei LIU Xiao-ping LUO Zhuo CHEN Wan-jiang ZENG Su-hua CHEN Ding ma ling CHEN ling FENG Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Pediatrics Tongji HospitalTongji Medical CollegeHuazhong Universiry 0f Science and TechnologyWuhan 430030 China Deparment of Traditional Chinese Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Based on the New Diagnosis and Treatment Scheme for Novel Coronavirus Infected Pneumonia(Trial Edition 5),combined with our current clinical treatment experience,we recently proposed a revision of the first edition of“Guidance for maternal and fctal management during pneumonia epidemics of novel coronavirus infection in the wuhan Tongji Hospital".This article focused on the issues of greatest concern of pregnant women including severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection diagnostic criteria,inspection precautions,drug treatment options,indications and methods of termination of pregnancy,postpartum fever,breastfeeding considerations,mode of mother-to-child transmission,neonatal isolation and advice on nconatal nursing,to provide valuable experience for better management of SARS-CoV-2 infection in pregnant women and newborns.

关键词： COVID-19 pneumonia pregnant women newborn disease management