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现场总线技术PROFIBUS在烟草制丝电控系统中的应用

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微计算机信息 2006年第11S期22卷 70-72,166页

作者：林龙广州卷烟二厂生产一部 510310

本文简要介绍了现场总线技术的PROFIBUS特点,分析了利用PROFIBUS在设计烟草制丝电控系统中的系统组成、系统功能、系统特性,并给出实现方法。

关键词： PROFIBUS 特点组成功能特性方法

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准噶尔盆地油气勘探新思路

新疆石油地质 2007年第6期28卷 661-667页

作者：林隆栋中国石油新疆油田分公司新疆克拉玛依834000

对传统的有机生油凹陷理论提出质疑,并对盆地内已出现的三大油气富集带进行地质解释,指出这是盆地内富含油气的特殊的深部地壳结构(上地幔上拱、中下或中上地壳内存在低速高导层、以近南北向为主的壳幔断裂发育)与其上沉积盖层相互依存... 详细信息

对传统的有机生油凹陷理论提出质疑,并对盆地内已出现的三大油气富集带进行地质解释,指出这是盆地内富含油气的特殊的深部地壳结构(上地幔上拱、中下或中上地壳内存在低速高导层、以近南北向为主的壳幔断裂发育)与其上沉积盖层相互依存、相互作用的结果。对今后盆地勘探提出了与传统有机生油凹陷理论完全不同的新思路、新举措。

关键词：深部地壳结构幔源底辟构造俯冲消减碰撞带

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佤族的药食同源文化

云南民族大学学报（哲学社会科学版） 2005年第5期22卷 100-102页

作者：龙鳞云南民族大学民族研究所云南昆明650031

佤族医药文化有着悠久的历史和民族特色,在其医药文化中,有一个十分显著的特点,就是药食同源,药和食相伴相生。在饮食结构中,强调药物的功能;而在药物的功能中,注重食物的药用特性。

关键词：佤族药食同源医药文化

In vivo evaluation of early renal damage in type 2 diabetic patients on 3.0 T MR diffusion tensor imaging

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World Journal of Radiology 2018年第8期10卷 83-90页

作者： Yu-Ting Wang Xiong Yan Hong Pu long-lin Yin Department of Radiology Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of China

AIM To investigate the utility of renal diffusion tensor imaging(DTI) to detect early renal damage in patients with type 2 *** Twenty-six diabetic patients(12 with microalbuminuria(MAU), and 14 with normoalbuminuria) and fourteen healthy volunteers were prospectively included in this study. Renal DTI on 3.0 T MR was performed, and estimated glomerular filtration rate(e GFR) was recorded for each subject. Mean cortical and medullary fractional anisotropy(FA) values were calculated by placing multiple representative regions of interest. Mean FA values were statistically compared among groups. Correlations between FA values and e GFR were evaluated. RESULTS Both cortical and medullary FA were significantly reduced in diabetic patients compared to healthy controls(0.403 ± 0.064 vs 0.463 ± 0.047, P = 0.004, and 0.556 ± 0.084 vs 0.645 ± 0.076, P = 0.002, respectively). Cortical FA was significantly lower in diabetic patients with NAU than healthy controls(0.412 ± 0.068 vs 0.463 ± 0.047, P = 0.02). Medullary FA in diabetic patients with NAU and healthy controls were similar(0.582 ± 0.096 vs 0.645 ± 0.076, P = 0.06). Both cortical FA and medullary FA correlated with e GFR(r = 0.382, P = 0.015 and r = 0.552, P = 0.000, respectively).CONCLUSION FA of renal parenchyma on DTI might serve as a more sensitive biomarker of early diabetic nephropathy than MAU.

关键词： Renal diffusion tensor imaging Fractional anisotropy Diabetic nephropathy Microalbuminuria Estimated GFR Correlation

Joint Detection of Serum Vitamin D,Body Mass Index,and Tumor Necrosis Factor Alpha for the Diagnosis of Crohn’s Disease

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Current Medical Science 2023年第3期43卷 496-504页

作者： Ying ZHENG Jing-hong LI Shan-ying LIAO Yi-ming FU Yan-jun ZHANG Jun-long lin Xin-bin CHEN Wei-hong SHA Shi-xue DAI Wen-jun MA Department of Nutrition Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou510080China The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510080China Department of Gastroenterology Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou 510080China The First School of Clinical Medicine&Nanfang Hospital Southern Medical UniversityGuangzhou 510080China Department of Gastroenterology Guangdong Provincial Geriatrics InstituteNational Key Clinical SpecialtyGuangdong Provincial People's HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou 510080China

Objective Vitamin D(VD)deficiency was reported to contribute to the progression of Crohn’s disease(CD)and affect the prognosis of CD *** study investigated the role of serum VD,body mass index(BMI),and tumor necrosis factor alpha(TNF-α)in the diagnosis of Crohn’s *** CD patients(n=76)and healthy subjects(n=76)were enrolled between May 2019 and December *** serum 25-hydroxyvitamin D[25(OH)D]levels,BMI,and TNF-αlevels,together with other biochemical parameters,were assessed before *** diagnostic efficacy of the single and joint detection of serum 25(OH)D,BMI,and TNF-αwas determined using receiver operating characteristic(ROC)*** The levels of 25(OH)D,BMI,and nutritional indicators,including hemoglobin,total protein,albumin,and high-density lipoprotein cholesterol,were much lower,and the TNF-αlevels were much higher in the CD patients than in the healthy subjects(Plinical practice.

关键词： Crohn’s disease vitamin D body mass index tumor necrosis factor alpha

Study on the Application of iTRAQ Technology in Retinal Apoptosis Protein in Diabetic Retinopathy Mice

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Chinese Journal of Biomedical Engineering(English Edition) 2023年第4期32卷 161-169,184页

作者： QUE Li-dan lin Yi-long QUE Xiu-ping LIU Bin longyan First Affiliated Hospital of Fujian Medical University Longyan Fujian 364000China Quanzhou Maternal and Child Health Hospital Children's Hospital Quanzhou Fujian 362000China

Objective:Using isobaric tags for relative and absolute quantitation(i TRAQ)technology to study differential protein expression in the retinal tissue of DR mouse models,providing proteomic evidence at the protein level for the pathogenesis of ***:Firstly,establish diabetic mice and DR mice models,use i TRAQ technology to detect the retinal tissue samples of normal control group and DR model group mice,label the total retinal proteins of mice with i TRAQ reagent,and analyze them using mass spectrometry *** the differential proteins of the two groups using BioWorks TM 3.0 software,and conduct interaction feature analysis on the different proteins using the STRING ***:The i TRAQ technology detected a total of 406 different proteins between the diabetes and normal control groups,with 19 of them closely related to retinal cell *** them,significantly different proteins include acyl-CoA dehydrogenase short chain specific(ACADS),ataxin-10(ATXN10),BCL-2-associated X protein(BAX),caspase-3(CASP3),collagen type IIα1 chain(COL4A2),glycyl-tRNA synthetase(GARS),glial fibrillary acidic protein(GFAP),legumain(LGMN),mucin-4(MUC4),N-myc downstream-regulated gene 1 protein(NDRG1),with ratios to internal controls in the normal group of 1.67,2.06,1.76,2.16,1.53,1.87,1.24,1.61,0.42,0.56,respectively;and there is a potential functional association between GFAP,CASP3,and BAX ***:In DR mice retinas,there are abnormal changes in the expression of a large number of apoptosis-related proteins.i TRAQ technology can effectively screen out key apoptosis proteins,among which GFAP,CASP3,and BAX may have adverse effects on the progression of DR by participating in the apoptosis *** application of i TRAQ technology can provide new technical support for proteomic research on apoptosis proteins.

关键词： diabetes retinopathy retinal apoptosis protein relative and absolute quantitation(iTRAQ)technology mice

Intravenous transplantation of mesenchymal stem cells attenuates oleic acid induced acute lung injury in rats

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Chinese Medical Journal 2012年第11期125卷 2012-2018页

作者： XU Yu-lin LIU Ying-long WANG Qiang LI Gang LU Xiao-dong KONG Bo Department of Pediatric Cardiac Surgery Center Fuwai Hospital ChineseAcademy of Medical Science and Peking Union Medical CollegeBeijing 100037 China

Background Acute lung injury （ALl） and end-stage acute respiratory distress syndrome （ARDS） were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated the importance of mesenchymal stem cells （MSCs） in maintaining the normal pulmonary endothelial and epithelial function as well as participating in modulating the inflammatory response and they are involved in epithelial and endothelial repair after injury. Here, our study demonstrates MSCs therapeutic potential in a rat model of ALI/ARDS. Methods Bone marrow derived MSCs were obtained from Sprague-Dawley （SD） rats and their differential potential was verified. ALl was induced in rats byoleic acid （OA）, and MSCs were transplanted intravenously. The lung injury and the concentration of cytokines in plasma and lung tissue extracts were assessed at 8 hours, 24 hours and 48 hours after OA-injection. Results The histological appearance and water content in rat lung tissue were significantly improved at different time points in rats treated with MSCs. The concentration of tumor necrosis factor-a and intercellular adhesion molecular-1 in rats plasma and lung tissue extracts were significantly inhibited after intravenous transplantation of MSCs, whereas interleukin-10 was significantly higher after MSCs transplantation at 8 hours, 24 hours and 48 hours after OA-challenge. Conclusions Intravenous transplantation of MSCs could maintain the integrity of the pulmonary alveolar-capillary barrier and modulate the inflammatory response to attenuate the experimental ALI/ARDS. Transplantation of MSCs could be a novel cell-based therapeutic strategy for prevention and treatment of ALI/ARDS.

关键词： acute lung injury, mesenchymal stem cells, tumor necrosis factor-a interleukin-10, oleic acid

Crystallographic Understanding of Photoelectric Properties for C_(60) Derivatives Applicable as Electron Transporting Materials in Perovskite Solar Cells

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Chemical Research in Chinese Universities 2022年第1期38卷 75-81页

作者： XING Zhou LI Shu-Hui XU Piao-Yang TIAN Han-Rui DENG lin-long YAO Yang-Rong CHEN Bin-Wen XIE Fang-Fang AN Ming-Wei YUN Da-Qin XIE Su-Yuan ZHENG Lan-Sun State Key Lab for Physical Chemistry of Solid Surfaces iChEM(Collaborative Innovation Center of Chemistry for Energy Materials)Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005P.R.China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005P.R.China College of Energy Xiamen UniversityXiamen 361005P.R.China

Hundreds of C60 derivatives stand out as electrontransporting materials(ETMs), for example, in perovskite solar cells(PSCs), due to their properties on electron extraction or defect passivation. However, it still lacks of guidelines to update C60-based ETMs with excellent photoelectric properties. In this work, crystallographic data of eight C60-based ETMs, including pristine C60 and the well-known PCBM as well as six newly synthesized fullerenes, are analyzed to establish the connections between derivatized structures and photoelectric properties for the typical carbon cluster of C60. In terms of packing centroid-centroid distance between neighboring carbon cages, the crystallographic data are useful for probing photoelectric properties, such as electrochemical properties, electron mobility and photovoltaic performances, and therefore facilitate to design novel C60-based ETMs for PSCs with high performances.

关键词： Perovskite solar cell(PSC) Electron transporting material(ETM) Fullerene Power conversion efficiency Crystallographic understanding

New amide alkaloids from Piper longum fruits

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Natural Products and Bioprospecting 2013年第6期3卷 277-281页

作者： Jun YANG Yao SU Ji-Feng LUO Wei GU Hong-Mei NIU Yan LI Yue-Hu WANG Chun-lin long Key Laboratory of Economic Plants and Biotechnology Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China College of Resources and Environmental Sciences Hebei Agricultural UniversityHebei 071000China State Key Laboratory of Phytochemisty and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China College of Life and Environmental Sciences Minzu University of ChinaBeijing 100081China

Three new amide alkaloids piperlongumamides A-C(1-3),together with 12 known ones(4-15),were isolated from the fruits of Piper *** structures of the new isolates were determined using spectroscopic data *** activity of these amides against HL-60(human leukemia),A-549(human lung cancer),MCF-7(human breast cancer),SMMC-7721(human liver cancer)and SW480(human rectal cancer)cell lines were *** B(11)exhibited weak inhibitory activity against HL-60(IC_(50)=21.32μM),A-549(IC_(50)=23.82μM)and MCF-7(IC_(50)=16.58μM)cell lines.

关键词： Piperaceae Piper longum amide alkaloids piperlongumamides piperchabamide B cytotoxicity