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Clinical efficacy of modified Kamikawa anastomosis in patients with laparoscopic proximal gastrectomy

World Journal of Gastrointestinal Surgery 2024年第1期16卷 113-123页

作者： Chu-Ying Wu jian-An lin Kai Ye Department of Gastrointestinal Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUND With the increasing incidence of proximal gastric cancer,laparoscopic proximal gastrectomy has been applied.However,reflux esophagitis often occurs after traditional esophagogastric anastomosis.In order to solve this problem,several methods of digestive tract reconstruction have emerged,but the most satisfying method remains to be discussed.Therefore,we modified traditional Kamikawa anastomosis to investigate the appropriate digestive tract reconstruction in laparo-scopic proximal gastrectomy.All the patients were successfully operated on without conversion to laparotomy.The duration of operation and digestive tract reconstruction were 203.500(150-224)min and 87.500(73-111)min,respectively.The intraoperative amount of bleeding was 20.500 mL±0.696 mL.The time of postoperative first flatus,the first postoperative fluid intake,and the postoperative length of stay were 2(1-3)d,4(3-5)d,and 9(8-10)d,respectively.All the patients were followed up for 12-23 months.The body mass index at 6 and 12 months after surgery were 22.577 kg/m2±3.098 kg/m2 and 22.594 kg/m2±3.207 kg/m2,respectively.The nutrition risk screening 2002 score,the patient-generated subjective global assessment score,and the gastroesophageal reflux disease scale score were good at 6 and 12 months after surgery.Reflux esophagitis and anastomotic stenosis were not observed in any of the patients during their 12-month postoperative gastroscopy or upper gastrointestinal tract visits.All the patients exhibited no tumor recurrence or metastasis.CONCLUSION The modified Kamikawa anastomosis is safe and feasible for laparoscopic proximal gastrectomy and has good antireflux effects and nutritional status.

关键词： Modified Kamikawa anastomosis Laparoscopy Proximal gastrectomy Antireflux

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Synthetic Control of Thorium Metal-Organic Frameworks for Sequencing and Sensing of Radioiodine Species

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Chinese Journal of Chemistry 2024年第1期42卷 20-28,I0004页

作者： Yu Ju Zi-jian Li xue Wang Jie Qiu Yiuhon Chan Zhi-Hui Zhang Mingyang He jian lin jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Changzhou UniversityNo.21Gehu Middle RoadChangzhouJiangsu 213164China Schoolof Nuclear Science and Technology Xi'an Jiaotong UniversityNo.28West Xianning RoadXianShaanxi 710049China Key Laboratoryof Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of Sciences2019JiaLuoRoadShanghai 201800China

Exploring the physiochemical properties and expanding the applications of actinide-containing materials is paramount to address the escalating challenge of radioactive waste accumulation.However,unlocking the full potential of these materials is largely crippled by the radiotoxicity of the actinides.We report here two porous and luminescent thorium-based metal-organic frameworks(Th-BITD-1 and Th-BITD-2)that serve as a bifunctional platform for sequencing and sensing of radioiodine,a much more radioactive fission product discharged during the nuclear fuel reprocessing.In particular,Th-BITD-1 displays better iodine uptake performance than Th-BITD-2 via the solution-based process and vapor diffusion with the maximum adsorption capacities of 831 and 1099 mg/g,respectively.Fur thermore,Th-BITD-1 can function as a highly sensitive luminescence sensor for iodate with a quenching constant(Ksv)of 6.6(5)×10^(3) M^(-1)and a detection limit of 2.02μM,respectively,outperforming 2.96(6)×10^(3)M^(-1)and 10.5μM of Th-BITD-2.Moreover,a positive correlation between the sensing efficacy and the iodate adsorption capacity has been revealed.This work highlights the opportunity in designing novel actinide-based MOFs for their potential applications in radiological fields,e.g.,radionuclide separation and detection.

关键词： Thorium Metal-organic frameworks Adsorption Detection lodine Actinides Radiochemistry Luminescence

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COVID-19 pandemic amplified mortality rates among adolescents with bipolar disorder through family-related factors

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World Journal of Clinical Cases 2024年第11期12卷 1929-1935页

作者： Zhuo-Fan Ye Yi-Han Hong jian-lin Yang Meng-Qing Tan Ju-Min Xie Zu-Cai Xu Department of Neurology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Hubei Key Laboratory of Renal Disease Occurrence and Intervention Medical SchoolHubei Polytechnic UniversityHuangshi 435003Hubei ProvinceChina Psychological Children's Ward Mental Health Center of HuangshiHuangshi 435111Hubei ProvinceChina The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Recently,a growing number of adolescents have been afflicted with mental disorders,with annual morbidity rates on the rise.This trend has been exacerbated by the global coronavirus disease 2019(COVID-19)pandemic,leading to a surge in suicide and self-harm rates among this demographic.AIM To investigate the impact of the COVID-19 pandemic on adolescent bipolar disorder(BD),along with the underlying factors contributing to heightened rates of suicide and self-harm among adolescents.METHODS A comprehensive statistical analysis was conducted utilizing clinical interviews and self-reports obtained from patients or their guardians.Diagnostic criteria for BDs were based on the Diagnostic and statistical manual of mental disorders,international classification of diseases-11,and the National institute of mental health research domain criteria.Statistical analyses were performed using SPSS 26.0 software,with significance set at Plines for the prevention,diagnosis and treatment of ad

关键词： Adolescents Bipolar disorder COVID-19 Suicide Self-harm

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Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis

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World Journal of Gastroenterology 2024年第15期30卷 2128-2142页

作者： Gui-Xiang Qian Zi-ling Xu Yong-Hai Li jian-lin Lu Xiang-Yi Bu Ming-Tong Wei Wei-Dong Jia Department of Hepatic Surgery Anhui Provincial HospitalThe First Affiliated Hospital of USTCDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Hepatic Surgery Anhui Provincial Hospital Affiliated to Anhui Medical UniversityAnhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Anorectal Surgery the First People’s Hospital of HefeiHefei 230001Anhui ProvinceChina

BACKGROUND The prognosis for hepatocellular carcinoma(HCC)in the presence of cirrhosis is unfavourable,primarily attributable to the high incidence of recurrence.AIM To develop a machine learning model for predicting early recurrence(ER)of posthepatectomy HCC in patients with cirrhosis and to stratify patients’overall survival(OS)based on the predicted risk of recurrence.METHODS In this retrospective study,214 HCC patients with cirrhosis who underwent curative hepatectomy were examined.Radiomics feature selection was conducted using the least absolute shrinkage and selection operator and recursive feature elimination methods.Clinical-radiologic features were selected through univariate and multivariate logistic regression analyses.Five machine learning methods were used for model comparison,aiming to identify the optimal model.The model’s performance was evaluated using the receiver operating characteristic curve[area under the curve(AUC)],calibration,and decision curve analysis.Additionally,the Kaplan-Meier(K-M)curve was used to evaluate the stratification effect of the model on patient OS.RESULTS Within this study,the most effective predictive performance for ER of post-hepatectomy HCC in the background of cirrhosis was demonstrated by a model that integrated radiomics features and clinical-radiologic features.In the training cohort,this model attained an AUC of 0.844,while in the validation cohort,it achieved a value of 0.790.The K-M curves illustrated that the combined model not only facilitated risk stratification but also exhibited significant discriminatory ability concerning patients’OS.CONCLUSION The combined model,integrating both radiomics and clinical-radiologic characteristics,exhibited excellent performance in HCC with cirrhosis.The K-M curves assessing OS revealed statistically significant differences.

关键词： Machine learning Radiomics Hepatocellular carcinoma Cirrhosis Early recurrence Overall survival Computed tomography Prognosis Risk factor Delta-radiomics

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A Hybrid Music Recommendation Model Based on Personalized Measurement and Game Theory

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Chinese Journal of Electronics 2023年第6期32卷 1319-1328页

作者： WU Yun lin jian MA Yanlong The State Key Laboratory of Public Big Data Guizhou University College of Computer Science and Technology Guizhou University

Music recommendation algorithms, from the perspective of real-time, can be classified into two categories: offline recommendation algorithms and online recommendation algorithms. To improve music recommendation accuracy, especially for the new music(users have no historic listening records on it), and real-time recommendation ability, and solve the interest drift problem simultaneously, we propose a hybrid music recommendation model based on personalized measurement and game theory. This model can be separated into two parts: an offline recommendation part(OFFLRP) and an online recommendation part(ONLRP). In the offline part, we emphasize users personalization. We introduce two metrics named user pursue-novelty degree(UPND) and music popularity(MP) to improve the traditional items-based collaborative filtering algorithm. In the online part, we try to solve the interest drift problem, which is a thorny problem in the offline part. We propose a novel online recommendation algorithm based on game theory. Experiments verify that the hybrid music recommendation model has higher new music recommendation accuracy, decent dynamical personalized recommendation ability, and real-time recommendation capability, and can substantially mitigate the problem of interest drift.

关键词： Music recommendation Personalization Game theory Interest drift Hybrid music recommendation model

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关键生物信号枢纽的细胞原位单分子定位超高分辨率解析

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中国激光 2024年第3期51卷 20-36页

作者：林健陈鑫厦门大学生命科学学院福建厦门361102

细胞内存在大量性质各异的大分子复合物,它们是控制生命活动的核心信号枢纽。荧光显微成像因其分子特异性、细胞原位可视化和多色标记解析等优势,已成为当今生物学研究不可或缺的技术手段。而突破光学衍射极限的超分辨光学成像技术为进... 详细信息

细胞内存在大量性质各异的大分子复合物,它们是控制生命活动的核心信号枢纽。荧光显微成像因其分子特异性、细胞原位可视化和多色标记解析等优势,已成为当今生物学研究不可或缺的技术手段。而突破光学衍射极限的超分辨光学成像技术为进一步理解多种重要生物百纳米信号体的原位结构和功能调节提供了亚细胞尺度甚至单分子精度的研究思路和方案。首先阐述了超分辨成像和单分子定位显微镜的基本原理,介绍了近年来在多项生命科学研究中的代表性应用案例,结合实际研究经验总结了超分辨光学成像技术在使用中面临的诸多挑战和未来发展方向,提出了基于原位纳米成像解析信号枢纽组织结构将有力促进新型疾病治疗靶点和策略的开发。

关键词：生物光学超分辨成像单分子定位生物信号体信号转导

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Clinical analysis of secondary penile cancer:a case series at a tertiary referral center in China

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Asian Journal of Andrology 2024年第2期26卷 225-226页

作者： Xiao-Yu Li Chun-Ru Xu Xing Ji Zhen-Peng Zhu Zhen-Ke Guo Tian-Yu Cai jian lin Department of Urology Peking University First HospitalBeijing 100034China Institute of Urology Peking UniversityBeijing 100034China National Urological Cancer Center Beijing 100034China Beijing Key Laboratory of Urogenital Diseases(Male)Molecular Diagnosis and Treatment Center Beijing 100034China

Dear Editor,Secondary penile cancer is an extremely rare condition that refers to the metastasis of other malignancies to the penis.There are limited reports on secondary penile cancer in Asian populations,and perceptions about this disease are extremely scarce.We reviewed and analyzed the data of patients diagnosed with secondary penile cancer based on the pathological findings at Peking University First Hospital in Beijing,China,aiming to expand the clinical reference for this rare disease.

关键词： cancer rare finding

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Maximum power and corresponding efficiency of an irreversible blue heat engine for harnessing waste heat and salinity gradient energy

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Science China(Technological Sciences) 2022年第3期65卷 646-656页

作者： lin jian XIE Shan jianG ChenXing SUN YiFei CHEN JinCan ZHAO YingRu College of Energy Xiamen UniversityXiamen 361002China Department of Physics Xiamen UniversityXiamen 361002China

In this study,a novel irreversible cyclic model of a capacitive mixing blue heat engine mainly consisting of super capacitors,charging and discharging circuits,a heat source,as well as two water sources with given salt concentrations is established for harvesting salinity gradient energy and waste heat.Additionally,the effects of the charging voltage and ratio of the minimum to maximum surface electric charge density on the thermodynamic efficiency and power output of the cycle are discussed.The maximum power output of the cycle is calculated.The optimized ranges of efficiency and power output as well as the temperatures of two isothermal processes are determined.It is established that during the isoelectric quantity process,there is not only an increase in thermal voltage owing to the temperature difference,but also an increase in concentration voltage owing to the salinity gradient.Consequently,the blue heat engine can obtain higher energy conversion efficiency than a conventional heat engine.When the temperature ratio of the heat source to the heat sink is 1.233,the maximum efficiency can reach approximately36%.The results obtained can promote the application of capacitive mixing technology in real life,reducing the consumption of fossil fuels.

关键词： blue heat engine capacitance mixing salinity gradient energy thermodynamic analysis efficiency at maximum power output

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Construction Direction and Development Path of Digital Educational Resources in the Era of New Educational Infrastructure Construction

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Frontiers of Education in China 2022年第4期17卷 510-531页

作者： KE Qingchao lin jian MA Xiufang BAO Tingting School of Information Technology in Education South China Normal UniversityGuangzhou 510631China

Digital educational resources have become essential elements of modern educational public services.China’s national program on new educational infrastructure construction has proposed to take new infrastructure construction of digital educational resources as one of the critical tasks.This paper aims to provide a theoretical basis for advancing the reform and development of digital educational resources in the new era.It classifies the current development and realistic challenges of China’s digital educational resources,and summaries and interprets the directions of the three construction projects of new type resources and tools,the resource supply system,and the resource supervisory system.It depicts the prospect of digital educational resource construction in the intelligent era in the combination of the strategic layout of the policies on new educational infrastructure construction.It also discusses such key technologies supporting new infrastructure construction of digital educational resources as multimodal learning analytics,disciplinary knowledge graphs,machine learning,and blockchain.It finally proposes a specific development path for new infrastructure construction of digital educational resources.

关键词： new educational infrastructure construction digital educational resources disciplinary knowledge graph resource supply system

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现代产业学院建设:主要共性问题分析及对策建议

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高等工程教育研究 2024年第1期 1-9页

作者：林健清华大学教育研究院清华大学教育研究院国家工程教育多学科交叉创新引智基地

现代产业学院建设是我国高等教育界的一项重大行动,其目标是服务和引领国家和区域产业发展,对于实现产教深度融合、培养卓越工程人才和主动服务区域产业发展具有重要意义。目前,现代产业学院建设工作在探索中稳步推进,在取得较为丰硕的... 详细信息

现代产业学院建设是我国高等教育界的一项重大行动,其目标是服务和引领国家和区域产业发展,对于实现产教深度融合、培养卓越工程人才和主动服务区域产业发展具有重要意义。目前,现代产业学院建设工作在探索中稳步推进,在取得较为丰硕的成果的同时,也面临不少困难和问题,这些困难和问题的解决关系到现代产业学院的建设目标能否最终实现。本文针对首批50所现代产业学院在建设过程中遇到的10个主要共性问题,分别从专兼职教师队伍建设、提高各主体参与学院建设的积极性及其它共性问题三部分展开分析研究并提出相应的对策建议,以期为高校、企业、各级政府、行业组织和科研院所等相关主体参与现代产业学院建设提供参考和借鉴。

关键词：现代产业学院教师队伍建设积极性多方协同产教融合

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