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Successful reconstruction of an ankle defect with free tissue transfer in a hemophilia A patient with repetitive hemoarthrosis:A case report

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World Journal of Clinical Cases 2023年第17期11卷 4079-4083页

作者： Dong Yun Lee SooA lim SuRak Eo jung Soo Yoon Department of Plastic and Reconstructive Surgery DongGuk University Medical CenterGoYang 10326South Korea

BACKGROUND Hemophilia, an uncommon yet consequential hereditary bleeding disorder, manifests as two clinically indistinguishable forms that hinder the normal functioning of the coagulation cascade. This impairment renders individuals more susceptible to excessive bleeding during significant surgical interventions. Moreover, individuals with severe hemophilia frequently encounter recurring hemarthrosis, resulting in progressive joint destruction and, subsequently, the need for hip and knee replacement *** SUMMARY The patient was a 53-year-old man with hemophilia A as the underlying disease and had self-injected factor Ⅷ twice weekly for several decades. He had undergone ankle fusion surgery for recurrent hemarthrosis at the Department of Orthopedic Surgery 1 mo prior and was referred to our department because of skin necrosis after a hematoma at the surgical site. An anterolateral thigh perforator free flap was created after three cycles of factor Ⅷ administration in addition to the concomitant administration of tranexamic acid(TXA)(Transamin 250 mg cap, 1 cap tid, q8h). After the operation, from postoperative days(PODs) 1-5, the factor Ⅷ dose and interval were maintained, and q12h administration was tapered to q24h administration after POD 6. Because the patient’s flap was stable 12 d after the operation, factor Ⅷ administration was tapered to twice a week. At 6 mo follow-up, the patient recovered well without any *** To the best of our knowledge, there are very few reports of successful free flaps in patients with hemophilia, and none have been reported in patients with hemophilia A. Moreover, there are several reports on the efficacy of TXA in free flaps in general patients;however, there are no case reports of combining factor Ⅷ and TXA in patients with hemophilia. Therefore, we report this case to contribute to future academic research.

关键词： Free tissue transfer Anterolateral thigh free flap Hemophilia A Hemoarthrosis Factor VIII Tranexamic acid Case report

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Texture development and grain boundary phase formation in Ce-and Ce-La-substituted Nd-Fe-B magnets during hot-deformation process

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Journal of Materials Science & Technology 2022年第31期126卷 71-79页

作者： Ga-Yeong Kim Tae-hoon Kim Hee-Ryoung Cha Sang-hyub Lee Dong-Hwan Kim Yang-Do Kim jung-Goo Lee Department of Magnetic Materials Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Engineering Pusan National UniversityBusan 46241Republic of Korea R&D Center Star Group Ind.Co.Ltd.Daegu 42714Republic of Korea

In this study,the influence of Ce-and Ce-La-substitution for Nd in Nd-Fe-B magnets on their magnetic and microstructural changes in the course of the hot-deformation process was investigated to gain insight into further reducing the Nd content in fine-grained Nd-Fe-B hot-deformed *** found that the[001]texture and microstructure of the RE-rich grain boundary phases,which are the factors that de-termine the remanence and coercivity of hot-deformed magnets,were deteriorated by the Ce-and *** is because the volume fraction of the RE-rich liquid formed in the grain boundaries during the hot-press and hot-deformation decreased due to the Ce-and Ce-La-substitution,thereby in-creasing the friction between the 2:14:1 grains while the c-axes of grains were aligned by grain rotation and decreasing the RE concentration of grain boundary *** particular,the Ce-La-co-substitution further prevented the liquid formation within the grain boundaries of the magnets during hot-press and hot-deformation because the wettability of the RE-rich liquid on the 2:14:1 grains became poor when La was substituted for Nd in the 2:14:1 *** results indicate that there is room for further im-provement in both the remanence and coercivity of the Ce-and Ce-La-substituted magnets by intro-ducing additional liquid into the grain boundaries prior to hot-press and *** applying the Nd-Cu infiltration process to the melt-spun ribbons(intermediate infiltration,I-infiltration),both the remanence and coercivity of the Nd-saving(Nd 0.7 Ce 0.3)-Fe-B and(Nd 0.7 Ce 0.225 La 0.075)-Fe-B hot-deformed magnets were successfully improved.

关键词： Nd-Fe-B magnets Hot-deformation Nd-saving Ce-substitution La-substitution Infiltration

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Gouty tenosynovitis with compartment syndrome in the hand: A case report

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World Journal of Clinical Cases 2023年第30期11卷 7492-7496页

作者： Dong Yun Lee SuRak Eo SooA lim jung Soo Yoon Department of Plastic and Reconstructive Surgery DongGuk University Medical CenterGoYang 10326South Korea

BACKGROUND Gout is a common type of inflammatory arthritis caused by the deposition of monosodium urate crystals in the joints and surrounding *** typically appears with abrupt and intense pain,redness,and swelling in the affected *** frequently targets the lower extremities,such as the big ***,rarely,gout can manifest in atypical locations,including the hands,leading to an uncommon presentation known as gouty ***,it can result in significant morbidity owing to the potential for severe complications,such as myonecrosis and compartment *** SUMMARY An 82-year-old male patient with a history of hypertension,cerebral infarction,Parkinson's disease,and recurrent gout attacks sought medical attention because of progressive pain and swelling in the right *** findings revealed forearm swelling,raising concerns of possible tenosynovitis,bursitis,septic arthritis,and compartment syndrome.A fasciotomy was performed to decompress the patient’s hands and *** procedure revealed diffuse tenosynovitis,tophi with a pus-like discharge surrounding the carpal tunnel,and involvement of the flexor and extensor tendon ***,microbiological investigations,including Gram staining,acid-fast bacilli,tuberculosis,and nontuberculous mycobacteria,yielded negative *** patient was ultimately diagnosed with a severe gouty attack with compartment syndrome and *** arthritis and infectious flexor tenosynovitis were ruled *** debridement and inflammation control were initiated,followed by staged closure with a skin *** Septic-like complications can occur in the absence of infection in severe gout attacks with pus-like discharges due to compartment syndrome and *** can be used to differentiate between gouty attacks,septic arthritis,and infectious *** of the flexor and extensor muscles,as in this case,is *** study contributes to the literature

关键词： Compartment syndrome Extensor compartment Gout Tenosynovitis Case report

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A surgical technique using the gastroepiploic vein for portal inflow restoration in living donor liver transplantation in a patient with diffuse portomesenteric thrombosis

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国际肝胆胰疾病杂志:英文版 2023年第5期22卷 537-540页

作者： Sang-hoon Kim Deok-Bog Moon Woo-Hyoung Kang Dong-Hwan jung Sung-Gyu Lee Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical Center and University of Ulsan College of Medicine88 Olympic-ro 43-gilSongpa-guSeoul 05505Korea

Portal vein thrombosis(PVT)is no longer a definitive contraindication in liver transplants(LTs)[1].Complex vascular reconstructions such as cavoportal hemitransposition(CPHT)[2–5],renoportal anastomosis(RPA)[6,7],and use of sizable collaterals(pericholedochal varix[8,9],coronary vein,peripancreatic or perigastroesophageal varices[10],right superior colic vein[11],ileocolic vein[12],and left gastric vein[13]),or combined liverpancreas-small bowel transplant[14]are required for portal inflow in patients with total portosplenomesenteric thrombosis.

关键词： thrombosis anastomosis portal

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Nanocrystalline Iron Pyrophosphate-Regulated Amorphous Phosphate Overlayer for Enhancing Solar Water Oxidation

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Nano-Micro Letters 2022年第12期14卷 387-400页

作者： Chengkai Xia Yuankai Li Minyeong Je Jaekyum Kim Sung Min Cho Chang Hyuck Choi Heechae Choi Tae-hoon Kim jung Kyu Kim School of Chemical Engineering Sungkyunkwan University(SKKU)2066 Seobu-roJangan-guSuwon 16419Republic of Korea Theoretical Materials and Chemistry Group Institute of Inorganic ChemistryUniversity of CologneGreinstr.650939 CologneGermany Department of Chemistry Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Materials Science and Engineering Engineering Research CenterChonnam National UniversityGwangju 61186Republic of Korea

A rational regulation of the solar water splitting reaction pathway by adjusting the surface composition and phase structure of catalysts is a substantial approach to ameliorate the sluggish reaction kinetics and improve the energy conversion *** this study,we demonstrate a nanocrystalline iron pyrophosphate(Fe_(4)(P_(2)O_(7))_(3),FePy)-regulated hybrid overlayer with amorphous iron phosphate(FePO_(4),FePi)on the surface of metal oxide nanostructure with boosted photoelectrochemical(PEC)water *** manipulating the facile electrochemical surface treatment followed by the phosphating process,nanocrystalline FePy is localized in the FePi amorphous overlayer to form a heterogeneous hybrid *** FePy-regulated hybrid overlayer(FePy@FePi)results in significantly enhanced PEC performance with long-term *** with the homogeneous FePi amorphous overlayer,FePy@FePi can improve the charge transfer efficiency more significantly,from 60% of FePi to 79%of FePy@*** density-functional theory calculations reveal that the coexistence of FePi and FePy phases on the surface of metal oxide results in much better oxygen evolution reaction kinetics,where the FePi was found to have a typical down-hill reaction for the conversion from OH*to O_(2),while FePy has a low free energy for the formation of OH*.

关键词： Water oxidation Photoelectrochemical cell Metal pyrophosphate Electrochemical surface treatment

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Clinical outcomes of endoscopic resection of superficial nonampullary duodenal epithelial tumors: A 10-year retrospective, single-center study

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World Journal of Gastrointestinal Surgery 2022年第4期14卷 329-340页

作者： Joon Hyun Cho Ki Young lim Eun jung Lee Si Hyung Lee Division of Gastroenterology and Hepatology Department of Internal MedicineYeungnam University College of MedicineDaegu 42415South Korea

BACKGROUND Although premalignant duodenal lesions such as adenomas are uncommon,the incidences of these lesions have increased in recent times,and thus,the demand for minimally invasive treatments such as endoscopic resection(ER)has also ***,ER in the duodenum is more challenging than ER in other locations of the gastrointestinal *** To evaluate the safety and efficacy of ER for superficial nonampullary duodenal epithelial tumors(SNADETs)METHODS We performed a retrospective observational study on 56 consecutive patients(58 lesions)diagnosed with SNADETs that underwent ER from January 2011 to December 2020 at Yeungnam University *** demographics,lesion characteristics,and procedural and technical data were collected,and clinical outcomes,including procedure-related complications,completeness of resection,and recurrence were *** Median patient age was 57 years[range,26–77,30(53.6%)men].Endoscopic mucosal resection(EMR)was performed on 57 lesions(98.3%)and snare polypectomy on one(1.7%).Lesions consisted of 52 adenomas with low-grade dysplasia(89.7%),3 adenomas with high-grade dysplasia(5.2%),and 3 intramucosal adenocarcinomas(5.2%).There were 16 cases of intraprocedural bleeding(27.6%)and 1 case of delayed bleeding(1.7%),and all these 17 cases were successfully managed *** perforation or procedure-related death *** lesion size was associated with an increased risk of EMR-related bleeding(P=0.033).During a median follow-up period of 23 mo(range 6–100 mo),no local recurrence occurred,despite the fact one-third of the patients(19 lesions,32.8%)underwent piecemeal resection and 3 patients(3 lesions,5.2%)that underwent en bloc resection had a pathologically determined positive lateral *** patient died from a primary duodenal *** The majority of SNADETs can be safely and curatively resected by EMR,and thus,based on consideration of the high incidence of fatal complications attribut

关键词： Duodenum Adenoma Endoscopic mucosal resection Endoscopic resection Superficial nonampullary duodenal epithelial tumor

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Devastating complication of negative pressure wound therapy after deep inferior epigastric perforator free flap surgery:A case report

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World Journal of Clinical Cases 2023年第1期11卷 143-149页

作者： SooA lim Dong Yun Lee BumSik Kim jung Soo Yoon Yea Sik Han SuRak Eo Department of Plastic and Reconstructive Surgery DongGuk University Medical CenterGoYang 10326South Korea

BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent *** require immediate and appropriate management before they progress to an irreversible *** negative pressure wound therapy(NPWT)can prevent wound progression by increasing microcirculation,the inappropriate application of NPWT on complicationthreatened transferred and replanted tissues can induce an adverse *** SUMMARY A 48-year-old woman who underwent immediate breast reconstruction with a deep inferior epigastric artery perforator free *** applying a heating pad directly to the flap site,she sustained a deep second to third-degree contact burn over 30%of the transferred flap on postoperative 7 *** the necrotic changes had progressed,we applied an NPWT dressing over the burned area after en-bloc debridement of the transferred tissues on postoperative 21 *** 4 d of NPWT application,the exposed fatty tissues of the flap changed to dry and browncolored necrotic *** further debridement,we noted that the wound gradually reached total necrosis with a collapsed vascular pedicle of deep inferior epigastric *** Although NPWT has been shown to be successful for treating various wound types,the significant risk of NPWT application in short-lasting reconstructed flap wounds after thermal injury should be reminded.

关键词： Negative Pressure Wound Therapy Complications Breast reconstruction Deep inferior epigastric artery perforator Free flap Burn injury Case report

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An easily misdiagnosed and rare cause of traumatic back pain: bilateral renal infarction caused by traumatic bilateral renal artery dissection

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World Journal of Emergency Medicine 2023年第2期14卷 155-157页

作者： Woo Sung Choi Sung Youl Hyun Jae-Hyug Woo jung Han Hwang Yong Su lim Department of Emergency and Critical Care Medicine Gachon University Gil Medical CenterGachon University College of MedicineIncheon 21565Republic of Korea Department of Traumatology Gachon University Gil Medical CenterGachon University College of MedicineIncheon 21565Republic of Korea Department of Interventional Radiology Gachon University Gil Medical CenterGachon University College of MedicineIncheon 21565Republic of Korea

Dear editor,The incidence of renal infarction in patients admitted to the emergency department(ED) is approximately 0.004%.[1]Among patients with renal infarction, bilateral renal involvement has been reported in 28.6... 详细信息

关键词： traumatic infarction admitted

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Influences of ions and temperature on performance of carbon nano-particulates in supercapacitors with neutral aqueous electrolytes

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Particuology 2014年第4期12卷 9-17页

作者： jung hoon Chae George Zheng Chen Department of Chemical and Environmental Engineering and Energy and Sustainability Research DivisionFaculty of EngineeringUniversity of NottinghamNottinghamNG7 2RDUK

A commercial product of carbon nano-particles, Cabot MONACH 1300 pigment black （CMPB）, was studied for basic structural information and electrochemical performance in neutral aqueous electrolytes, aiming at applications in supercapacitors. As confirmed by SEM and HRTEM, the CMPB had a hierarchical struc- ture, containing basic 10 nm nano-spheres which combined into ca. 50 nm agglomerates which further aggregated into larger particles of micrometres. The capacitance of this commercial material was found to increase with decreasing the size of hydrous cation （Li＋→Na＋ → K＋）, instead of the cation crystal radius （K＋→ Na＋→Li＋） when coupled with the same anion （cl-）. In electrolytes with the same cation concentration （K＋）, changing the anion from the larger dianion （SO42 ） to the smaller monoanion （cl-） also increased the capacitance at high potential scan rates （〉50 mV/s）. Increasing electrolyte concentration produced expected effect, including raising the electrode capacitance, but lowering the equivalent series resistance （ESR）, charge transfer resistance （CTR）, and the diffusion resistance. At higher temperatures, the CMPB exhibited slightly higher capacitance, which does not agree with the Gouy-Chapman theory on electric double layer （EDL）. A hypothesis is proposed to account for the capacitance increase with temperature as a result of the CMPB opening up some micro-pores for more ions to access in response to the temperature increase.

关键词： Carbon nano-particlesSupercapacitorNeutral aqueous electrolytesIonic propertiesElectrochemistry

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Anaphylactic shock induced by polyethylene glycol after bowel preparation for the colorectal cancer surgery:A case report

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世界临床病例杂志 2023年第23期11卷 5589-5594页

作者： Go Woon Park Nahyeon Park jung Cheol Kuk Eung Jin Shin Dae Ro lim Department of General Surgery Soonchunhyang Bucheon HospitalBucheon 14584South Korea

BACKGROUND Polyethylene glycol(PEG)is widely used as an additive because of its hydrophilic and chemically inert ***,there are been increasing reports of PEG allergies,including anaphylaxis,although they are still *** case report aims to raise awareness,that the commonly used bowel cleansing agent containing PEG can cause serious allergic *** SUMMARY Prior to surgery for sigmoid colon cancer,a 63-year-old man was prescribed a bowel cleansing agent containing *** 30 min of ingestion,he developed symptoms of anaphylactic shock and did not respond to initial intramuscular epinephrine *** diagnosis of anaphylaxis to PEG,he was stabilized with fluid hydration and continuous norepinephrine *** While allergic reactions to PEG are rare,they can be ***,it is crucial for clinicians to be aware of this possibility and to diagnose and resuscitate patients immediately.

关键词： Polyethylene glycol Anaphylaxis Sigmoid colon cancer Bowel preparation Case report

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