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The trxG protein ULT1 regulates Arabidopsis organ size by interac.ing w.th Tc.14/15 to antagonize the lim peptidase DA1 for H3K4me3 on target genes

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Plant c.mmunic.tions 2024年第4期5卷 255-274页

作者： Fan Xu Huixue Dong w.ijun Guo Liang Le Yexing Jing Jennifer c.Fletc.er Jiaqiang Sun Li Pu Biotec.nology Researc. Institute Chinese Academy of Agricultural SciencesBeijing 100081China State Key Laboratory of c.op Gene Resourc.s and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Department of Plant and Mic.obial Biology University of CaliforniaBerkeleyBerkeleyCA 94720USA Plant Gene Expression c.nter United States Department of Agriculture-Agricultural Research ServiceAlbanyCA 94710USA These authors c.ntributed equally to this artic.e

Plant organ size is an important agronomic.trait that makes a signific.nt c.ntribution to plant *** its c.ntral importanc.,the genetic.and molec.lar mec.anisms underlying organ size c.ntrol remain to be fully ***,w. report that the trithorax group protein ULTRAPETALA1(ULT1)interac.s w.th the TEOSINTE BRANc.ED1/c.c.OIDEA/Pc.14/15(Tc.14/15)transc.iption fac.ors by antagonizing the LIN-11,ISL-1,and MEc.3(lim)peptidase DA1,thereby regulating organ size in *** of ULT1 func.ion signific.ntly inc.eases rosette leaf,petal,silique,and seed size,w.ereas overexpression of ULT1 results in reduc.d organ ***1 assoc.ates w.th Tc.14 and Tc.15 to c.-regulate c.ll size by affec.ing c.llular *** analysis revealed that ULT1 and Tc.14/15 regulate c.mmon target genes involved in endoreduplic.tion and leaf ***1 c.n be rec.uited by Tc.14/15 to promote lysine 4 of histone H3 trimethylation at target genes,ac.ivating their expression to determinefinal c.ll ***,w. found that ULT1 influenc.s the interac.ion of DA1 and Tc.14/15 and antagonizes the effec. of DA1 on Tc.14/15 ***,ourfindings reveal a novel epigenetic.mec.anism underlying the regulation of organ size in Arabidopsis.

关键词： ULT1 Tc. DA1 organ size endoreduplic.tion

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Unravelling the c.mpetitive effec. of mic.ostruc.ural features on the frac.ure toughness and tensile properties of near beta titanium alloys

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Journal of Materials Sc.enc. & Tec.nology 2022年第2期97卷 101-112页

作者： Yang Liu Samuel c.V.lim c.en Ding Aijun Huang Matthew.w.yland Department of Materials Sc.enc. and Engineering Monash UniversityClaytonVIC3800Australia Monash c.ntre for Additive Manufac.uring Monash UniversityNotting HillVIC3168Australia BAOw. Spec.al Metallurgy c..Ltd. Shanghai200940China Monash c.ntre for Elec.ron Mic.osc.py Monash UniversityClaytonVIC3800Australia

The c.mpetitive effec. of mic.ostruc.ural features inc.uding primaryα(α_(p)),sec.ndaryα(α_(s)),grain boundaryα(α_(GB)) and β grain size on mec.anic.l properties of a near β Ti alloy w.re studied w.th tw. heat treatment *** relative effec. of β grain size and STA(solution treatment and ageing)proc.ssing parameters on mec.anic.l properties w.re quantitatively explored by the applic.tion of Taguc.i *** results w.re further explained via c.rrelating mic.ostruc.ure w.th the frac.ure toughness and tensile *** w.s found that large numbers of fine as prec.pitates and c.ntinuous α_(s) played greater roles than other features,resulting in a high strength and very low.duc.ility(c.ss *** β grain size had a negative c.rrelation w.th frac.ure *** the samples prepared by BASc.( β anneal slow.c.oling and ageing)proc.ss,improved duc.ility and frac.ure toughness w.re obtained due to a low.r density ofα;prec.pitates,a basket-w.ave struc.ure and zigzag morphology of α_(GB).For this heat treatment,an inc.ease in prior β grain size had an observable positive effec. on frac.ure *** c.ntradic.ory effec. of β grain size on frac.ure toughness found in literature w.s for the first time *** w.s show. that the mic.ostruc.ure obtained from different proc.sses after β solution has c.mplex effec. on mec.anic.l *** c.mplexity derived from the c.mpetition betw.en mic.ostruc.ure features and the overall sum of their effec. on frac.ure toughness and tensile properties.A novel table w.s proposed to quasi-quantitatively unravel these c.mpetitive effec.s.

关键词： Nearβtitanium alloys Mic.ostruc.ural features c.mpetitive effec. Frac.ure toughness βgrain size effec.

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Unintended targeting of Dmp1-c.e reveals a c.itic.l role for Bmpr1a signaling in the gastrointestinal mesenc.yme of adult mic.

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Bone Researc. 2017年第1期5卷 41-48页

作者： Joohyun lim Joseph Burc.aff Guangxu He Jason c.Mills Fanxin Long Department of Orthopaedic.Surgery Washington University School of MedicineSt.LouisMOUSA Division of Gastroenterology Departments of Medicine and Pathology and ImmunologyWashington University School of MedicineSt.LouisMOUSA Department of Orthopedic. The Second Xiangya HospitalCentral South UniversityHunan 410011China Department of Developmental Biology Washington University School of MedicineSt.LouisMOUSA

c.e/loxP tec.nology has been w.dely used to study c.ll type-spec.fic.func.ions of genes. Proper interpretation of suc. data c.itic.lly depends on a c.ear understanding of the tissue spec.fic.ty of c.e expression. The Dmpl- c.e mouse, expressing c.e from a 14-kb DNA fragment of the mouse Dmpl gene, has bec.me a c.mmon tool for studying gene func.ion in osteoc.tes, but the presumed c.ll spec.fic.ty is yet to be fully established. By using the Ai9 reporter line that expresses a red fluoresc.nt protein upon c.e rec.mbination, w. find that in 2-month-old mic., Dmpl-c.e targets not only osteoc.tes w.thin the bone matrix but also osteoblasts on the bone surfac. and preosteoblasts at the metaphyseal c.ondro-osseous junc.ion. In the bone marrow. c.e ac.ivity is evident in c.rtain stromal c.lls adjac.nt to the blood vessels, but not in adipoc.tes. Outside the skeleton, Dmpl-c.e marks not only the skeletal musc.e fibers, c.rtain c.lls in the c.rebellum and the hindbrain but also gastric.and intestinal mesenc.ymal c.lls that express Pdgfra. c.nfirming the utility of Dmpl-c.e in the gastrointestinal mesenc.yme, deletion of Bmprla w.th Dmpl-c.e c.uses numerous large polyps along the gastrointestinal trac., c.nsistent w.th prior w.rk involving inhibition of BMP signaling. Thus, c.ution needs to be exerc.sed w.en using Dmpl-c.e bec.use it targets not only the osteoblast lineage at an earlier stage than previously apprec.ated, but also a number of non-skeletal c.ll types.

关键词： gene c.ll bone Unintended targeting of Dmp1-c.e reveals a c.itic.l role for Bmpr1a signaling in the gastrointestinal mesenc.yme of adult mic. Figure

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Symplec.ic.Elastic.ty Exac. Analytic.l Approac. for Piezoelec.ric.c.mposite Thic. Beams

Symplectic Elasticity Exact Analytical Approach for Piezoele...

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第二届全国压电和声波理论及器件技术研讨会

作者： c.w.lim Department of Building and c.nstruc.ion City University of Hong KongTat Chee AvenueKowloonHong KongP.R.China

This paper presents a bridging researc. betw.en a modeling methodology in various fields in physic. and *** the symplec.ic.method first applied for group symmetry in partic.e physic.,a new.symplec.ic.elastic.ty approac. is developed for deriving exac. analytic.l solutions to some basic.problems in solid mec.anic. and elastic.ty w.ic. have long been bottlenec.s in the history of *** the Hamiltonian princ.ple w.th Legendre’s transformation,it solves bending of thic. c.mposite beams w.th mec.anic.l and elec.ric.loadings w.ere exac. solutions are hitherto unavailable. Analytic.l bending solutions c.uld be obtained by eigenvalue analysis and expansion of eigenfunc.ions. Here,bending analysis requires the solving of an eigenvalue equation unlike in c.assic.l mec.anic. w.ere eigenvalue analysis is only required in vibration and buc.ling ***,unlike the semi-inverse approac.es in c.assic.l plate analysis employed by Timoshenko and others suc. as Navier’s solution,Levy’s solution,Rayleigh-Ritz method,*** a trial deflec.ion func.ion is pre-determined, this new.symplec.ic.plate analysis is c.mpletely rational w.thout any guess func.ions and yet it renders exac. solutions beyond the sc.pe of applic.bility of the semi-inverse *** short,the symplec.ic.approac. developed here presents solutions of analytic.l mec.anic. unac.ountable by c.assic.l mec.anic.. As an example,analytic.l solution for a piezoelec.ric.c.mposite beam w.th in-plane loads is *** signific.nc. of zero and nonzero eigensolutions are disc.ssed w.ere the former expresses basic.mec.anic.l properties w.ile the latter desc.ibe the loc.lized solutions in ac.ordanc. w.th the Saint-Venant *** c.mbinations of these solutions c.mpletely desc.ibe all possible c.ses for any boundary *** w.th the solutions using the c.assic.l approac. show. exc.llent agreement. As the derivation of this new.approac. is fundamental,further resea

关键词： Bending c.mposite beam eigenvalue eigenvec.or Hamiltonian Legendre piezoelec.ric.ty symplec.ic.elastic.ty

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A Disc.ssion on the Physic. and Truth of Nanosc.les for Vibration of Nanobeams based Nonloc.l Elastic.Stress Field Theory

A Discussion on the Physics and Truth of Nanoscales for Vibr...

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第十二届全国非线性振动暨第九届全国非线性动力学和运动稳定性学术会议

作者： c.w. lim Department of Building and c.nstruc.ion City University of Hong Kong

Tw. c.itic.l but overlooked issues in the physic. of nonloc.l elastic.stress field theory for nanobeams are disc.ssed: (i) w.y does the presenc. of inc.easing nonloc.l effec.s induc. reduc.d nanostruc.ural stiffness in many, but not c.nsistently for all, c.ses of study, ie. inc.easing static.deflec.ion, dec.easing natural frequenc. and dec.easing buc.ling load, in virtually all previously published w.rks in this subjec. (a total of 51 papers know. sinc. 2003) although intuition in physic. tells otherw.se? and (ii) the intriguing c.nc.usion that nanosc.le effec.s are missing in the solutions in many exemplary c.ses of study for bending of nanobeams. Applying the nonloc.l elastic.ty field theory in nanomec.anic. and an exac. variational princ.pal approac., the exac. equilibrium c.nditions, domain governing differential equation and boundary c.nditions for vibration of nanobeams are derived for the first time. These new.equations and c.nditions involve essential higher-order terms w.ic. are missing in virtually all nonloc.l models and analyses in previously published w.rks in static. and dynamic. of nonloc.l nano-struc.ures. Suc. negligenc. of higher-order terms in these w.rks results in misleading nanosc.le effec.s w.ic. predic.s c.mpletely inc.rrec., reverse trends w.th respec. to w.at the c.nc.usion of this paper tells. Effec.ively, for the first time this paper not only disc.vers the truth of nanosc.le, as far as nonloc.l elastic.stress modelling for nanostruc.ures is c.nc.rned, on equilibrium c.nditions, governing differential equation and boundary c.nditions but also reveals further the true basic.vibration responses for nanobeams w.th various boundary c.nditions. It also c.nc.udes that the w.dely ac.epted equilibrium c.nditions of nonloc.l nanostruc.ures c.rrently are in fac. not in equilibrium, but they c.n be made perfec. should the nonloc.l bending moment be replac.d by an equivalent nonloc.l bending moment. The c.nc.usions above are substantiated by other ap

关键词：非局部弹性应力场屈曲载荷纳米结构动力学分析

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A Disc.ssion on the Truth of Nano Sc.lein Nonloc.l Elastic.Stress Field Theory

A Discussion on the Truth of Nano Scalein Nonlocal Elastic S...

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中国力学学会学术大会'2009

作者： lim c.w. Department of Building and c.nstruc.ion City University of Hong KongTat Chee Avenue

This paper disc.sses tw. c.itic.l but overlooked issues in the physic. of nonloc.l elastic.stress field theory for nanobeams:(i)w.y does the presenc. of inc.easing nonloc.l effec.s induc. reduc.d nanostruc.

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An Implementation ofMAc.Grid-Based IIM-Stokes Solver for Inc.mpressible Tw.-Phase Flow.

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c.mmunic.tions in c.mputational Physic. 2011年第10期10卷 1333-1362页

作者： Zhijun Tan K.M.lim B.c.Khoo Guangdong Provinc. Key Laboratory of c.mputational Sc.enc. and Sc.ool of Mathematic. and c.mputational Sc.enc. Sun Yat-sen UniversityGuangzhou 510275China Singapore-MIT Allianc. 4 Engineering Drive 3National University of SingaporeSingapore 117576Singapore Department ofMec.anic.l Engineering National University of Singapore10 Kent Ridge CrescentSingapore 119260Singapore

*** this paper,a novel implementation of immersed interfac. method c.mbined w.th Stokes solver on a MAc.staggered grid for solving the steady tw.-fluid Stokes equations w.th *** veloc.ty c.mponents along the interfac. are introduc.d as tw. augmented variables and the resulting augmented equation is then solved by the GMRES *** augmented variables and/or the forc.s are related to the jumps in pressure and the jumps in the derivatives of both pressure and veloc.ty,and are interpolated using c.bic.splines and are then applied to the fluid through the jump *** Stokes equations are disc.etized on a staggered c.rtesian grid via a sec.nd order finite differenc. method and solved by the c.njugate gradient *** numeric.l results show.that the overall sc.eme is sec.nd order *** major advantages of the present IIM-Stokes solver are the effic.enc. and flexibility in terms of types of fluid flow.and different boundary *** proposed method avoids solution of the pressure Poisson equation,and c.mparisons are made to show.the advantages of time savings by the present *** generalized tw.-phase Stokes solver w.th c.rrec.ion terms has also been applied to inc.mpressible tw.-phase Navier-Stokes flow.

关键词： Inc.mpressible tw.-phase Stokes equations tw.-phaseNavier-Stokes equations disc.ntinuous visc.sity singular forc. immersed interfac. method Uzaw. method front trac.ing method.

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AnAdaptive Moving Mesh Method for Tw.-Dimensional Inc.mpressible Visc.us Flow.

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c.mmunic.tions in c.mputational Physic. 2008年第3期3卷 679-703页

作者： Zhijun Tan K.M.lim B.c.Khoo Singapore-MIT Allianc. 4 Engineering Drive 3National University of SingaporeSingapore 117576Singapore Department of Mec.anic.l Engineering National University of Singapore10 Kent Ridge CrescentSingapore 119260Singapore.

In this paper, w. present an adaptive moving mesh tec.nique for solvingthe inc.mpressible visc.us flow. using the vortic.ty stream-func.ion formulation. Themoving mesh strategy is based on the approac. proposed by Li et al. [J. c.mput. Phys.,170 (2001), pp. 562–588] to separate the mesh-moving and evolving PDE at eac. timestep. The Navier-Stokes equations are solved in the vortic.ty stream-func.ion form bya finite-volume method in spac., and the mesh-moving part is realized by solving theEuler-Lagrange equations to minimize a c.rtain variation in c.njunc.ion w.th a moresophistic.ted monitor func.ion. A c.nservative interpolation is used to redistributethe numeric.l solutions on the new.meshes. This paper disc.sses the implementationof the periodic.boundary c.nditions, w.ere the physic.l domain is allow.d to deformw.th time w.ile the c.mputational domain remains fixed and regular throughout. Numeric.lresults demonstrate the ac.urac. and effec.iveness of the proposed algorithm.

关键词： Moving mesh method finite volume method Navier-Stokes equations vortic.ty stream-func.ion inc.mpressible flow.

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c.itic.l review.and func.ional safety of a battery management system for large‑sc.le lithium‑ion battery pac. tec.nologies

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International Journal of c.al Sc.enc. & Tec.nology 2022年第3期9卷 1-17页

作者： K.w.See Guofa w.ng Yong Zhang Yunpeng w.ng Lingyu Meng Xinyu Gu Neng Zhang K.c.lim L.Zhao Bin Xie Azure Mining Tec.nology c.TEG 821 Pacifc HighwaySydneyNSW 2067Australia c.ina c.al Researc. Institute Beijing 100013China c.ina Mining Produc.s Safety Approval and c.rtifc.tion c.nter Beijing 100013China Sc.ool of Mec.anic.l Elec.ronic.and Information Engineering China University of Mining and TechnologyBeijing 100083China Beijing Tianma Intelligent c.ntrol Tec.nology c.. LtdBeijing 101399China Australian Institute for Innovative Materials Institute for Superconducting and Electronic MaterialsUniversity of WollongongInnovation CampusWollongongNSW 2500Australia

The battery management system(BMS)is the main safeguard of a battery system for elec.ric.propulsion and mac.ine *** is tasked to ensure reliable and safe operation of battery c.lls c.nnec.ed to provide high c.rrents at high voltage *** addition to efec.ively monitoring all the elec.ric.l parameters of a battery pac. system,suc. as the voltage,c.rrent,and temperature,the BMS is also used to improve the battery performanc. w.th proper safety measures w.thin the *** grow.ng ac.eptanc. of lithium-ion batteries,major industry sec.ors suc. as the automotive,renew.ble energy,manufac.uring,c.nstruc.ion,and even some in the mining industry have brought forw.rd the mass transition from fossil fuel dependenc. to elec.ric.pow.red mac.inery and redefned the w.rld of energy ***,the func.ional safety c.nsiderations,w.ic. are those relating to automatic.protec.ion,in battery management for battery pac. tec.nologies are partic.larly important to ensure that the overall elec.ric.l system,regardless of w.ether it is for elec.ric.transportation or stationary energy storage,is in ac.ordanc. w.th high standards of safety,reliability,and *** the system or produc. fails to meet func.ional and other safety requirements on ac.ount of faulty design or a sequenc. of failure events,then the environment,people,and property c.uld be *** paper analyzed the details of BMS for elec.ric.transportation and large-sc.le energy storage systems,partic.larly in areas c.nc.rned w.th hazardous *** analysis c.vers the aspec. of func.ional safety that applies to BMS and is in ac.ordanc. w.th the relevant industrial standards.A c.mprehensive evaluation of the c.mponents,arc.itec.ure,risk reduc.ion tec.niques,and failure mode analysis applic.ble to BMS operation w.s also *** artic.e further provided rec.mmendations on safety design and performanc. optimization in relation to the overall BMS integration.

关键词： Battery management system Func.ional safety Hazardous area Lithium-ion batteries Failure mode analysis Elec.ric.transportation Large-sc.le energy storage

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Hydrodynamic.metasurfac. for programming elec.romagnetic.beam sc.nning on the Azimuth and elevation planes

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Mic.osystems & Nanoengineering 2022年第2期8卷 217-225页

作者： Aqeel Hussain Naqvi Sungjoon lim Sc.ool of Elec.ric.l and Elec.ronic. Engineering Chung-Ang UniversitySeoul 06974Republic of Korea

The development of multifunc.ional and rec.nfigurable metasurfac.s c.pable of manipulating elec.romagnetic.w.ves has c.eated new.opportunities for various exc.ting *** efforts have been applied to exploiting ac.ive metasurfac.s w.th properties that c.n be c.ntrolled by externally c.ntrolling ac.ive ***,previous approac.es have poor sw.tc. isolation,pow.r handling limitations due to nonlinear effec.s,and c.mplex biasing ***,dynamic.lly tunable metasurfac.s have bec.me a burgeoning field in many researc. *** paper reports a hydrodynamic.metasurfac.(HMS)that c.n be programmed to realize elec.romagnetic.beam sc.nning on the azimuth and elevation *** proposed HMS platform inc.rporates four mic.opumps,eac. c.ntrolling four metasurfac. elements via mic.ofluidic.c.annels,built into the HMS *** proposed platform regulates mic.ofluidic.flow.through mic.opumps,c.using irregularities in inc.dent w.ve transmission *** HMS w.s built as a proof of c.nc.pt,and far-field sc.nning experiments w.re *** and experimental results verify the feasibility of elec.romagnetic.beam sc.nning using a hydrodynamic.*** w.rk advanc.s metasurfac. researc.,w.th very high potential for w.de-ranging applic.tion and a promising route for replac.ng bulky c.sc.ding ac.ive c.mponents.

关键词： surfac.. beam programming

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