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Journal of Integrative Plant Biology 2007年第4期49卷 523-530页

作者： Yi liao Da-quan Xu Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences the Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences Shanghai 200032 China

After saturating light illumination for 3 h the potential photochemical efficiency of photosystem Ⅱ （PSII）（FJF,, the ratio of variable to maximal fluorescence） decreased markedly and recovered basically to the level before saturating light illumination after dark recovery for 3 h in both soybean and wheat leaves, indicating that the decline in FJ/Fm is a reversible down-regulation. Also, the saturating light illumination led to significant decreases in the low temperature （77 K） chlorophyll fluorescence parameters F685 （chlorophyll a fluorescence peaked at 685 nm） and F685/F735 （F735, chlorophyll a fluorescence peaked at 735 nm） in soybean leaves but not in wheat leaves. Moreover, trypsin （a protease） treatment resulted in a remarkable decrease in the amounts of PsbS protein （a nuclear gene psbS-encoded 22 kDa protein） in the thylakoids from saturating light-illuminated （SI）, but not in those from darkadapted （DT） and dark-recovered （DRT） soybean leaves. However, the treatment did not cause such a decrease in amounts of the PsbS protein in the thylakoids from saturating light-illuminated wheat leaves. These results support the conclusion that saturating light illumination induces a reversible dissociation of some light-harvesting complex Ⅱ （LHClI） from PSII reaction center complex in soybean leaf but not in wheat leaf.

关键词： chlorophyll fluorescence light-harvesting complex Ⅱ PsbS protein reversible dissociation soybean trypsin.

Heat Transfer Effectiveness of Three-Fluid Separated Heat Pipe Exchanger

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Journal of Thermal Science 2011年第1期20卷 64-69页

作者： Chengming Shi Yang Wang Ying Yang quan liao College of Power Engineering Chongqing University Chongqing 400044 China

A heat transfer model for three-fluid separated heat pipe exchanger was analyzed,and the temperature transfer matrix for general three-fluid separated heat exchanger working in parallel-flow or counter-flow mode was *** was found that the forms of temperature transfer matrix are similar for heat pipe rows with equal or different heat transfer surface ***,by using the temperature transfer matrix of the heat pipe exchanger,the relationship between heat transfer effectiveness θ 1,θ 2 and M,NTU,U,Δt i were derived for the exchanger operating in parallel-flow or counter-flow mode,and a simple special example was adopted to demonstrate the correctness of these relationships.

关键词： heat pipes three-fluid heat exchangers heat transfer effectiveness temperature transfer matrix

Analysis and Application of Variable Conductance Heat Pipe Air Preheater

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Journal of Thermal Science 2011年第3期20卷 248-253页

作者： Chengming Shi Yang Wang quan liao Ying Yang College of Power Engineering Chongqing University Chongqing 400044 China

The heat transfer analysis of variable conductance heat pipe air preheater was carried out. The temperature trans-fer matrix was obtained for the air preheater that comprises several discrete heat transfer units with same or different heat transfer surface area in a parallel or counter flow mode. By using the temperature transfer matrix, the outlet fluid temperatures could be easily calculated for a given air preheater and inlet fluid temperatures. The active length of condenser in a variable conductance heat pipe is determined according to the flat interface model. With the same initial conditions, the comparisons between variable conductance heat-pipe air preheater and regular heat pipe air preheater has been analyzed and tested in terms of heat pipe wall temperature, heat transfer surface area and outlet fluid temperatures. Based on the real industrial applications, it has been confirmed that the variable conductance heat pipe air preheater has excellent performance of anti-corrosion and anti-ash-deposition especially at the variable working condition and the sulfur coal (5%-6% mass fraction of sulfur) condition.

关键词： variable conductance heat pipe air preheater anti-corrosion anti-ash deposition

Simulation of mesoscale interfacial properties using the lattice Boltzmann method

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Chinese Science Bulletin 2010年第29期55卷 3267-3273页

作者： ZENG JianBang LI LongJian liao quan HUANG YanPing PAN LiangMing Key Laboratory of Low-grade Energy Utilization Technologies and Systems (Chongqing University) Ministry of Education Chongqing 400030 China National Key Laboratory of Bubble Physics and Natural Circulation ofNPIC Chengdu 610041 China

We derive the mesoscopic interparticle potentials from macroscopic thermodynamics for van der Waals,Redlich-Kwong,and Redlich-Kwong-Soave equations of state and find that all these potentials are very similar to the Lennard-Jones *** investigate the interfacial property at the mesoscale level,we incorporate free energy functions into the single-component multiphase lattice Boltzmann model and obtain the saturated density coexistence curves and interface mass density profiles across the interface using this method with different equations of *** simulation results accurately reproduce the properties of equilib-rium *** results for single-component phase transitions indicate that a bubble-growth process is obtained and the equilibrium phase diagram is achieved at a given *** free energy,the interfacial energy coefficient,and other properties of nonequilibrium thermodynamic parameters,which are used to examine interfacial properties,are obtained in these simulations,and all these parameters are found to obey irreversible thermodynamics.

关键词：界面性能格子玻尔兹曼方法中尺度格子Boltzmann模型模拟状态方程法热力学性质非平衡热力学

Simulation of phase transition process using lattice Boltzmann method

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Chinese Science Bulletin 2009年第24期54卷 4596-4603页

作者： ZENG JianBang LI LongJian liao quan CUI WenZhi CHEN QingHua PAN LiangMing School of Power Engineering Chongqing University Chongqing 400030 China

A new lattice Boltzmann model based on SC model, is proposed to describe the liquid-vapor phase transitions. The new model is validated through the simulation of the one-component phase transition process. Compared with the simulation results of van der Waals gas and the Maxwell equal-area construction, the results of the new model have a better agreement with the analytical solutions than those of SC and Zhang models. Since the obtained temperature range and the maximum density ratio in this model are expanded, and the magnitude of maximum spurious current is only between those of SC and Zhang models, it is believed that this new model has better stability than SC and Zhang models. Consequently, the application scope of this new model is expanded compared with the existing phase transition models. According to the principle of the corresponding states in engineering thermodynamics, the simulations of ammonia and water phase transition process were implemented using this new model with different equations of state. Compared with the experimental data of ammonia and water, the results show that the Peng-Robinson is the best equation of state to describe the phase transition process of ammonia and water. Especially, the simulation results of ammonia with Peng-Robinson equation of state have an excellent agreement with its experimental data. Therefore these simulation results have a significant influence on the real engineering applications.

关键词：数值模拟相变过程格子玻尔兹曼方法格子Boltzmann模型工程热力学状态方程实验数据范德华气体

Prognostic significance of SUVmax and serum carbohydrate antigen 19-9 in pancreatic cancer

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World Journal of Gastroenterology 2014年第19期20卷 5875-5880页

作者： Jian-Guo Zhao Ya Hu quan liao Zhe-Yu Niu Yu-Pei Zhao Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical College

AIM: To investigate the prognostic significance of pretreatment standardized maximum uptake value (SUVmax) and serum carbohydrate antigen (CA)19-9 in pancreatic cancer.

关键词： Pancreatic cancer Maximum standardized uptake value Carbohydrate antigen 19-9 Prognostic factors

Source of silica and its implications for organic matter enrichment in the Upper Ordovician-Lower Silurian black shale in western Hubei Province,China:Insights from geochemical and petrological analysis

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Petroleum Science 2022年第1期19卷 74-90页

作者： quan-Sheng Cai Ming-Yi Hu Bao-Min Zhang Ngong Ngia An Liu Rui-quan liao Oumar Kane Hai Li Zhong-Gui Hu Qing-Jie Deng Jun-Jun Shen School of Geosciences Yangtze UniversityWuhanHubei 430100China Key Laboratory of Tectonics and Petroleum Resources of Ministry of Education(China University of Geosciences) WuhanHubei 430074China Wuhan Center of China Geological Survey WuhanHubei 430205China Department of Geology University of BueaP.O.Box 63BueaSouthwestCameroon School of Petroleum Engineering Yangtze UniversityWuhanHubei 430100China

To improve the understanding of the relationship between silica source and organic matter accumulation,the origin of silica and its implications for organic matter enrichment in the Upper OrdovicianLower Silurian(O_(3)w-S_(1)l)black shale in western Hubei Province in the middle Yangtze area,were investigated through geochemical and petrological *** results show that the O_(3)w-S_(1)l black shale is mainly composed of five lithofacies with varying graptolite abundance,total organic carbon(TOC),and silica *** silica and terrigenous siliciclastic input constitute the main silica sources in O_(3)w-S_(1)l black shale and they exhibit an upward inverse variation trend interpreted to be related to sea-level ***,with the increase in biogenic silica content or decrease in terrigenous siliciclastic input,TOC values in black shale initially rise and then fall,which is different from originally expected simple linear *** infer that organic matter enrichment and the distribution of silica from different origins are controlled by sea-level changes and variations in terrigenous input in a continental shelf with little hydrothermal *** environment with appropriate sea level and terrigenous input should be most favorable for organic matter accumulation,rather than one with excessive high sea level and less terrigenous input.

关键词： Biogenic silica Terrigenous siliciclastic input Organic matter enrichment Black shale Continental shelf Sea-level change Wufeng-Longmaxi formations

Xiangshaliujunzi Decoction for the treatment of diabetic gastroparesis: A systematic review

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World Journal of Gastroenterology 2014年第2期20卷 561-568页

作者： Jia-Xing Tian Min Li Jiang-quan liao Wen-Ke Liu Xiao-Lin Tong Department of Endocrinology Guang'anmen HospitalChina Academy of Chinese Medical Sciences Graduate College Beijing University of Traditional Chinese Medicine

AIM: To assess the current clinical evidence of the effectiveness of Xiangshaliujunzi Decoction (XSLJZD) for the treatment of diabetic gastroparesis (DGP).

关键词： Diabetic gastroparesis Xiangshaliujunzi Decoction Gastric emptying rate Gastrointestinal symptoms Systematic review

Recent studies of 5-fluorouracil resistance in pancreatic cancer

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World Journal of Gastroenterology 2014年第42期20卷 15682-15690页

作者： Wei-Bin Wang Yu Yang Yu-Pei Zhao Tai-Ping Zhang quan liao Hong Shu Department of General Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Resistance to 5-fluorouracil(5-FU), an important anticancer drug, is a serious challenge in the treatment of pancreatic cancer. Equilibrative nucleoside transporter 1 and multidrug-resistance protein(MRP) 5 and MRP8, rather than P-glycoprotein, play important roles in 5-FU transport. Thymidylate synthase, dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidine phosphorylase are four key enzymes involved in 5-FU metabolism. Other metabolic enzymes, including uridine monophosphate synthetase, also contribute to chemoresistance. Intracellular signaling pathways are an integrated network, and nuclear factor kappa-light-chain-enhancer of activated B cells, AKT and extracellular signal-regulated kinases are signaling pathways that are particularly relevant to 5-FU resistance. In addition, recent reports indicate that STAT-3 is a crucial survival protein. Proteomic assays provide a powerful tool for identifying target proteins and understanding the role of micro RNAs and stromal factors to facilitate the development of strategies to combat 5-FU resistance.

关键词： 5-fluorouracil Resistance Transporters Metabolic enzyme Signaling pathway Stromal factors MicroRNA Proteomic investigation

Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation

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Protein & Cell 2021年第2期12卷 128-144页

作者： Chengcheng Wang Taiping Zhang quan liao Menghua Dai Junchao Guo Xinyu Yang Wen Tan Dongxin Lin Chen Wu Yupei Zhao Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Etiology and Carcinogenesis National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Collaborative Innovation Center for Cancer Personalized Medicine Nanjing Medical UniversityNanjing 211166China Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China CAMS Oxford Institute(COI) Chinese Academy of Medical SciencesBeijing 100730China

Pancreatic ductal adenocarcinoma(PDAC)has poor prognosis due to limited therapeutic *** study examines the roles of genome-wide association study identified PDAC-associated genes as therapeutic *** have identified HNF4G gene whose silencing most effectively repressed PDAC cell ***4G overexpression is induced by the deficiency of transcriptional factor and tumor suppressor *** HNF4G are correlated with SMAD4 deficiency in PDAC tumor samples and associated with metastasis and poor survival time in xenograft animal model and in patients with PDAC(log-rank P=0.036;HR=1.60,95%CI=1.03–2.47).We have found that Metformin suppresses HNF4G activity via AMPK-mediated phosphorylation-coupled ubiquitination degradation and inhibits in vitro invasion and in vivo metastasis of PDAC cells with SMAD4 ***,Metformin treatment significantly improve clinical outcomes and survival in patients with SMAD4-deficient PDAC(log-rank P=0.022;HR=0.31,95%CI=0.14–0.68)but not in patients with SMAD4-normal *** analysis shows that HNF4G may act in PDAC through the cell-cell junction *** results indicate that SMAD4 deficiency-induced overexpression of HNF4G plays a critical oncogenic role in PDAC progression and metastasis but may form a druggable target for Metformin treatment.

关键词： pancreatic cancer HNF4G SMAD4 deficiency SMAD4-deficient PDAC Metformin