检索结果-南通市图书馆

维普期刊数据库

The evolution,pathogenicity and transmissibility of quadruple reassortant H1N2 swine influenza virus in China:A potential threat to public health

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2024年第2期39卷 205-217页

作者： Xinxin Cui Jinhuan Ma Zifeng Pang Lingzhi Chi Cuishan Mai Hanlin Liu ming liao Hailiang Sun College of Veterinary Medicine South China Agricultural UniversityGuangzhou510642China Key Laboratory of Zoonosis Control and Prevention of Guangdong Province South China Agricultural UniversityGuangzhou510642China National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control South China Agricultural UniversityGuangzhou510642China Shandong Vocational Animal Science and Veterinary College Weifang261061China Institute of Animal Health Guangdong Academy of Agricultural SciencesGuangzhou510640China

Swine are regarded as“intermediate hosts”or“mixing vessels”of influenza viruses,capable of generating strains with pandemic potential.From 2020 to 2021,we conducted surveillance on swine H1N2 influenza(swH1N2)viruses in swine farms located in Guangdong,Yunnan,and Guizhou provinces in southern China,as well as Henan and Shandong provinces in northern China.We systematically analyzed the evolution and pathogenicity of swH1N2 isolates,and characterized their replication and transmission abilities.The isolated viruses are quadruple reassortant H1N2 viruses containing genes from pdm/09 H1N1(PB2,PB1,PA and NP genes),triple-reassortant swine(NS gene),Eurasian Avian-like(HA and M genes),and recent human H3N2(NA gene)lineages.The NA,PB2,and NP of SW/188/20 and SW/198/20 show high gene similarities to A/Guangdong/Yue Fang277/2017(H3N2).The HA gene of swH1N2 exhibits a high evolutionary rate.The five swH1N2 isolates replicate efficiently in human,canine,and swine cells,as well as in the turbinate,trachea,and lungs of mice.A/swine/Shandong/198/2020 strain efficiently replicates in the respiratory tract of pigs and effectively transmitted among them.Collectively,these current swH1N2 viruses possess zoonotic potential,highlighting the need for strengthened surveillance of swH1N2 viruses.

关键词： Swine influenza virus(SIV) H1N2 Evolution Replication Pathogenicity Zoonotic potential

Slow magnetic relaxation and photoluminescence behaviors of dilanthanide complexes bearing N8O2 donor macrocyclic ligand

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第7期42卷 1298-1303页

作者： Pei-Yu liao Yu-Quan Qi Zhen Li Jian-Hua Jia ming-Liang Tong Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education School of ChemistrySun Yat-Sen University

On account of the complicated magnetic exchange interactions between lanthanide ions,binuclear lanthanide complexes have broad application prospect in the field of single-molecule magnets.Therefore,it is necessary to develop reasonable bridging ligands to manipulate the directional assembly of binuclear lanthanide complexes.Herein,we selected the macrocyclic ligand LN8O2to build up two new dilanthanide complexes [Ln2(LN8O2)（OpyO）2（H2O）2]（NO3）2(1-Ln,Ln=Dy,Tb;LN8O2=hexamethyl-tetraaza-dioxe-dipyrazolacycloicosaphane-2,9,12,19-tetraene;OpyOH=2-pyridinol-1-oxide).Dynamic magnetic studies show that 1-Dy exhibits slow relaxation behavior under a 1 kOe applied field.Further fitting analysis of relaxation times gives the effective energy barrier of 38.2 cm-1,and reveals that the slow magnetic relaxation behavior is dominated by the Orbach and Raman processes.High-resolution luminescence emission spectrum indicates the energy gap of 36.8 cm-1 between the ground state and the first excited state,consistent with the magnetic measurement results.1-Tb exhibits brilliant characteristic green light emission under UV light excitation.The absolute quantum yield of 1-Tb is 44.8%,and its first-order fitted decay lifetime is 779.21 μs at room temperature.This study provides the way for directional construction of high-performance molecular materials with magnetic and optical dualfunction.

关键词： Dilanthanide complexes Macrocyclic ligand Photoluminescence behavior Rare earths Single-molecule magnets

Copper-coated Porous Polyimide as Ultralight and Safe Current Collectors for Advanced LIBs

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第4期42卷 521-531页

作者： Cun-Sheng Liu Jun-Qi Hu Ting-Ting Mao Song-Yi liao Ru-ming Feng Yi-Dong Liu Yong-Gang Min School of Materials and Energy Guangdong University of TechnologyGuangzhou510006China College of Chemistry and Chemical Engineering Zhongkai University of Agriculture and EngineeringGuangzhou510225China Shanwei Branch of Advanced Energy Science and Technology Guangdong Laboratory Shanwei516600China

Metallic copper is widely used as current collector(CC) for graphite anode of lithium-ion batteries(LIBs) due to its high electrical conductivity and electrochemical stability. However, the large volume density of commercial copper foil(~8.9 g·cm^(-3)) limits the increase of energy density of battery. Here, copper-coated porous polyimide(Cu@PPI) was prepared by vacuum evaporation as collector for the graphite anode. The sandwich structure connects the copper metal on both sides of the collector with excellent electrical conductivity. Compared to commercial Cu foil, Cu@PPI has lighter mass(≤3.9 mg for disc of 12 mm diameter versus 9.9 mg of ~10 μm Cu foil) and lower volume density(≤3.3 g·cm^(-3)). In addition, the porous structure allows of better adhesion of reactive substances and electrochemical properties than pure Cu foils. It is estimated that the energy density of Cu@PPI should be much higher than that of Cu foil. This strategy should be applicable for other current collectors.

关键词： Copper-coated Vacuum evaporation Porous polyimide(PPI) Current collector(CC) LIBs

维普期刊数据库

Towards sustainable adversarial training with successive perturbation generation

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2024年第4期25卷 527-539页

作者： Wei LIN Lichuan liao College of Computer Science and Mathematics Fujian University of TechnologyFuzhou 350118China College of Economics and Management Xi’an University of TechnologyXi’an 710048China Fujian Provincial Key Laboratory of Big Data Mining and Applications Fujian University of TechnologyFuzhou 350118China

Adversarial training with online-generated adversarial examples has achieved promising performance in defending adversarial attacks and improving robustness of convolutional neural network models.However,most existing adversarial training methods are dedicated to finding strong adversarial examples for forcing the model to learn the adversarial data distribution,which inevitably imposes a large computational overhead and results in a decrease in the generalization performance on clean data.In this paper,we show that progressively enhancing the adversarial strength of adversarial examples across training epochs can effectively improve the model robustness,and appropriate model shifting can preserve the generalization performance of models in conjunction with negligible computational cost.To this end,we propose a successive perturbation generation scheme for adversarial training(SPGAT),which progressively strengthens the adversarial examples by adding the perturbations on adversarial examples transferred from the previous epoch and shifts models across the epochs to improve the efficiency of adversarial training.The proposed SPGAT is both efficient and effective;e.g.,the computation time of our method is 900 min as against the 4100 min duration observed in the case of standard adversarial training,and the performance boost is more than 7%and 3%in terms of adversarial accuracy and clean accuracy,respectively.We extensively evaluate the SPGAT on various datasets,including small-scale MNIST,middle-scale CIFAR-10,and large-scale CIFAR-100.The experimental results show that our method is more efficient while performing favorably against state-of-the-art methods.

关键词： Adversarial training Adversarial attack Stochastic weight average Machine learning Model generalization

Effects of microenvironment and biological behavior on the paracrine function of stem cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 135-147页

作者： Zhixin Xue Yunjun liao Ye Li The Department of Plastic and Cosmetic Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China

Mesenchymal stem cells(MSCs),the most well-studied cell type in the field of stem cell therapy,have multi-lineage differentiation and self-renewal potential.MsC-based thera-pies have been used to treat diverse diseases because of their ability to potently repair tissue and locally restore function.An increasing body of evidence demonstrates that paracrine func-tion is central to the effects of MsC-based therapy.Growth factors,cytokines,chemokines,extracellular matrix components,and extracellular vehicles all contribute to the beneficial ef-fects of MSCs on tissue regeneration and repair.The paracrine substances secreted by MSCs change depending on the tissue microenvironment and biological behavior.In this review,we discuss the bioactive substances secreted by MsCs depending on the microenvironment and biological behavior and their regulatory mechanisms,which explain their potential to treat human diseases,to provide new ideas for further research and clinical cell-free therapy.

关键词： Bioactive behavior Mesenchymal stem cells Microenvironment Paracrine Secretome

An indicator model for assessing community resilience to the COVID-19 pandemic and its validation: A case study in Hong Kong

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Safety Science and Resilience 2024年第2期5卷 222-234页

作者： Nan liao Muhammad Nawaz Departnent of Geography Faculty Art and Social SciencesSingapore 65166666Singapore

The COVID-19 outbreak had a significant negative impact on the world,and the fifth wave of COVID-19 in Hong Kong brought a considerable shock to Chinese society.There is a growing call for more resilient cities.However,empirical evidence and validation of modeling studies of resilience indicators for urban community responses to the COVID-19 pandemic still need to be provided.In this study,a resilience assessment indicator model comprising 4 subsystems,7 indicators,and 12 variables was developed to assess the resilience of Hong Kong communities in response to COVID-19(i.e.,Resilience Index).Furthermore,this study utilized regression models such as geographically weighted regression(GWR)and multiscale GWR(MGWR)to validate the resilience model proposed in this study at the model and variable levels.In the regression model,the Resilience Index and the individual variables in the resilience model are explanatory variables,and the outcomes of the COVID-19 pandemic(confirmed cases,confirmation rate,discharged cases,discharge rate)are dependent variables.The results showed that:(i)the resilience of Hong Kong communities to the COvID-19 pandemic was not strong in general and showed some clustered spatial distribution characteristics;(i)the validation results at the model level showed that the Resilience Index did not explain the consequences of the COvID-19 pandemic to a high degree;(ii)the validation results at the variable level showed that the MGWR model was the best at identifying the relationships between explanatory variables and the dependent variable;and(iv)compared with the model-level assessment results,the variable-level assessment explained the consequences of the COvID-19 pandemic better than the model level assessment results.The above analysis and the spatial distribution maps of the resilience variables can provide empirically based and targeted insights for policymakers.

关键词： Resilience Community resilience CoVID-19pandemic Resilience assessment indicator model Resilience model validation MGWR

Colorectal cancer’s burden attributable to a diet high in processed meat in the Belt and Road Initiative countries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第1期16卷 182-196页

作者： Gu Liu Chang-Min Li Fei Xie Qi-Lai Li Liang-Yan liao Wen-Jun Jiang Xiao-Pan Li Guan-ming Lu Department of Gastrointestinal Surgery The First Affiliated HospitalJinan UniversityGuangzhou 510630Guangdong ProvinceChina Department of Gastrointestinal Surgery Chenzhou Third People’s HospitalChenzhou 423000Hunan ProvinceChina Department of Gastrointestinal Surgery Chenzhou First People’s Hospital and the First Affiliated Hospital of Xiangnan UniversityChenzhou423000 Hunan ProvinceChina Department of Breast and Thyroid Surgery the Affiliated Hospital of Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Health Management Center Zhongshan HospitalShanghai Medical College of Fudan UniversityShanghai 200032China

BACKGROUND Colorectal cancer(CRC)plays a significant role in morbidity,mortality,and economic cost in the Belt and Road Initiative(“B and R”)countries.In addition,these countries have a substantial consumption of processed meat.However,the burden and trend of CRC in relation to the consumption of a diet high in processed meat(DHPM-CRC)in these“B and R”countries remain unknown.AIM To analyze the burden and trend of DHPM-CRC in the“B and R”countries from 1990 to 2019.METHODS We used the 2019 Global Burden of Disease Study to collate information regarding the burden of DHPM-CRC.Numbers and age-standardized rates(ASRs)of deaths along with the disability-adjusted life years(DALYs)were determined among the“B and R”countries in 1990 and 2019.Using joinpoint regression analysis,the average annual percent change(AAPC)was used to analyze the temporal trends of age-standardized DALYs rate(ASDALR)from 1990 to 2019 and in the final decade(2010–2019).RESULTS We found geographical differences in the burden of DHPM-CRC among“B and R”countries,with the three highest-ranking countries being the Russian Federation,China,and Ukraine in 1990,and China,the Russian Federation,and Poland in 2019.The burden of DHPM-CRC generally increased in most member countries from 1990 to 2019(all P<0.05).The absolute number of deaths and DALYs in DHPM-CRC were 3151.15[95%uncertainty interval(UI)665.74-5696.64]and 83249.31(95%UI 15628.64-151956.31)in China in 2019.However,the number of deaths(2627.57-2528.51)and DALYs(65867.39-55378.65)for DHPM-CRC in the Russian Federation has declined.The fastest increase in ASDALR for DHPM-CRC was observed in Vietnam,Southeast Asia,with an AAPC value of 3.90%[95%confidence interval(CI):3.63%-4.16%],whereas the fastest decline was observed in Kyrgyzstan,Central Asia,with an AAPC value of-2.05%(95%CI:-2.37%to-1.73%).A substantial upward trend in ASR of mortality,years lived with disability,years of life lost,and DALYs from DHPM-CRC changes in 1990-2019 and the final decade(2010-2019)for most Maritime Silk Route memb

关键词： Belt and Road Initiative countries Colorectal cancer Burden of disease Dietary risk factors Processed meat Disability-adjusted life years Trend analysis

Bioinspired polysaccharide-based nanocomposite membranes with robust wet mechanical properties for guided bone regeneration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2024年第3期11卷 215-226页

作者： Jian-Hong Xiao Zhen-Bang Zhang JiaHao Li Si-ming Chen Huai-Ling Gao YinXiu liao Lu Chen ZiShuo Wang YiFan Lu YuanZhen Hou HengAn Wu DuoHong Zou Shu-Hong Yu Department of Chemistry New Cornerstone Science Laboratory Institute of Biomimetic Materials&Chemistry Anhui Engineering Laboratory of Biomimetic MaterialsDivision of Nanomaterials&Chemistry Hefei National Research Center for Physical Sciences at the Microscale University of Science and Technology of China Department of Dental Implant Center Stomatologic Hospital and College Key Laboratory of Oral Diseases Research of Anhui Province Anhui Medical University CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics CAS Center for Excellence in Complex System Mechanics University of Science and Technology of China Department of Oral Surgery College of Stomatology National Clinical Research Center for Oral DiseasesShanghai Key Laboratory of Stomatology Shanghai Research Institute of Stomatology Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Institute of Innovative Materials(I2M) Department of Chemistry Department of Materials Science and Engineering Southern University of Science and Technology

Polysaccharide-based membranes with excellent mechanical properties are highly desired. However, severe mechanical deterioration under wet conditions limits their biomedical applications. Here, inspired by the structural heterogeneity of strong yet hydrated biological materials, we propose a strategy based on heterogeneous crosslink-and-hydration（HCH） of a molecule/nano dual-scale network to fabricate polysaccharide-based nanocomposites with robust wet mechanical properties. The heterogeneity lies in that the crosslink-and-hydration occurs in the molecule-network while the stress-bearing nanofiber-network remains unaffected. As one demonstration, a membrane assembled by bacterial cellulose nanofiber-network and Ca2+-crosslinked and hydrated sodium alginate molecule-network is designed. Studies show that the crosslinked-and-hydrated molecule-network restricts water invasion and boosts stress transfer of the nanofiber-network by serving as interfibrous bridge. Overall, the molecule-network makes the membrane hydrated and flexible; the nanofiber-network as stress-bearing component provides strength and toughness.The HCH dual-scale network featuring a cooperative effect stimulates the design of advanced biomaterials applied under wet conditions such as guided bone regeneration membranes.

关键词： bioinspiration heterogeneous crosslink-and-hydration dual-scale network nanocomposite membrane wet mechanical properties guided bone regeneration

Organic Brønsted Acid-Catalyzed Stereoselective Cationic RAFT Polymerization:The Effect of RAFT Agents

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第6期42卷 711-717页

作者： Zheng-Yi Zhang Zan Yang Yun liao Sai-Hu liao Key Laboratory of Molecule Synthesis and Function Discovery(Fujian Province University) College of ChemistryFuzhou UniversityFuzhou350108China State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China Beijing National Laboratory for Molecular Sciences Beijing100190China

The tacticity of vinyl polymers is a key factor affecting the properties of materials.Recently,organic Brønsted acids have been demonstrated as effective catalysts for the development of highly stereoselective cationic reversible addition-fragmentation chain transfer(RAFT)polymerizations of vinyl ethers,in which the use of RAFT agents could allow the control the molecular weight and tacticity of polymer products simultaneously.However,the effect of RAFT agents on the tacticity-regulation remains elusive and lacks of investigation.In this study,we synthesized four types of RAFT agents and evaluated their influence in the stereoselective cationic polymerization of isobutyl vinyl ether in the presence of PADI as a Brønsted acid catalyst,which unveils that the Z group of RAFT agents could not only affect the polydispersity of the products,but also exert a profound effect on the stereoselectivity.After extensive screening of the RAFT agents,high stereoregularity(isotacticity,90%m)was obtained when using dithiocarbonate ester-type RAFT agents with a benzyloxy Z group.

关键词： Bronsted acid catalysis Stereoselective cationic polymerization RAFT polymerization Chain transfer agents Tacticity

维普期刊数据库