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Review on microbial metabolomics of probiotics and pathogens:Methodologies and applications

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BIOCELL 2023年第1期47卷 91-107页

作者： XIN MENG XUE LI lianrong yang RUI YIN LEHUI QI QI GUO School of Pharmacy Heilongjiang University of Chinese MedicineHarbin150040China

In recent years,microbial metabolomics,a new field that has attracted wide attention,provides a map of metabolic pathways and clarifies the interaction mechanism between microorganisms and *** microorganisms are found in the human intestine,oral cavity,vagina,*** could maintain the good health of the host,while pathogens and an imbalance of bacterial flora lead to a series of diseases of the body and *** is a science for qualitative and quantitative analysis of all metabolites in an organism or biological system,which could provide key information to understand the related metabolic pathways and associated *** approach analyzes the final products of cellular regulatory processes,the level of which can be regarded as the ultimate response of the biological system to genetic or environmental *** metabolomics has been widely used in different research fields,such as microbial phenotypic classification,mutant screening,metabolic pathways,microbial metabolic engineering,fermentation engineering monitoring and optimization,microbial environmental pollution,and so ***,there are only a few reviews on microbial metabolomics of probiotics and *** review summarizes the main methodologies,including sample preparation,identification of metabolites,data processing,and *** applications in microbial metabolomics of probiotics and pathogens are also *** paper first summarized the research progress and application of microbial metabolomics from two aspects:probiotics and pathogenic *** and pathogenic bacteria do not exist independently most of the time;hence,these were reviewed in the research field of coexistence of probiotics and pathogenic bacteria,which was subdivided into important microbial research fields closely related to human health,including the human gut,oral cavity,food,and nutrition-related ***,the main problems and trends associated with micr

关键词： Probiotics Pathogens Microbial metabolomics Methodology Application

Reduced magma generation and its implications for the Pulang giant porphyry Cu-polymetallic deposit in Northwest Yunnan,China

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Acta Geochimica 2024年第4期43卷 802-813页

作者： Jingwei Guan Tao Ren Lei Wang Shenjin Guan lianrong Wu Baosheng Shi Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming 650093People’s Republic of China Diqing Nonferrous Metals Co. LtdShangri-La 674400People’s Republic of China

The Pulang giant porphyry Cu-Mo polymetallic deposit is located in the Zhongdian area in the center of the Sanjiang Tethys tectonic domain,which was formed by the westward subduction of the Garze-Litang oceanic slab beneath the Zhongza ***-pyrrhotite-pyritemolybdenite occurs as disseminations,veins,veinlets,and stockworks distributed in the K-silicate alteration zone in the monzonite porphyry,which is superimposed by *** chemical compositions of biotite and amphibole analyzed by electron probe microanalysis(EPMA)indicate that the ore-forming magma and exsolved fluids experienced a continuous decrease in the oxygen fugacity(fO_(2)).Primary amphibolite and biotite(type I)crystallized at relatively high temperatures(744-827°C)and low fO_(2)(log fO_(2)=−12.26 to−11.91)during the magmatic *** fluids exsolved from the magma have a relatively lower temperature(621-711°C)and fO_(2)(log fO_(2)=−14.36 to−13.32)than the original *** addition,the presence of a high abundance of pyrrhotite and an insufficiency of primary magnetite and sulfate in the ore(i.e.,anhydrite and gypsum)indicate that the deposit may be a reduced porphyry *** and fluid fO_(2)results,combined with previous research on magmatic fO_(2)at the Pulang deposit,indicate that the magma associated with the reduced Pulang ore assemblages was initially generated as a highly oxidized magma that was subsequently reduced by sedimentary rocks of the Tumugou Formation.

关键词： Porphyry deposit Oxygen fugacity(fO_(2)) Contamination of surrounding rock Pulang Zhongdian arc

High-quality Development of the Pearl River Night Tour in the Context of Deep Integration of Culture and Tourism

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Meteorological and Environmental Research 2024年第1期15卷 38-45页

作者： Juan JIANG lianrong PANG Guangdong Polytechnic of Industry and Commerce Guangzhou 510510China Lingnan Normal University Zhanjiang 524043China

Urban night tourism is a new form of urban tourism development and an important driving force for the prosperity of urban night *** the most prestigious business card among many night tour projects in Guangzhou,the Pearl River water night tour has contributed to the development of Guangzhou s night economy,which cannot be ***,in the process of rapid development,there are also problems such as diversified operators,insufficient integration of intangible cultural elements,excessive commercial attributes,issues of tourism facilities and service *** the new stage of integrated development of culture and tourism,how to use mutual promotion of culture and tourism in the Pearl River night tour to seek innovative paths for high-quality development in the future is the main problem expected to be solved in this ***,based on the perspective of culture and tourism integration,this paper analyzes the general situation and development status of the Pearl River night tour,and proposes five development strategies:the overall planning of culture and tourism integration,the deep integration of intangible cultural elements,the balance of commercial attributes and tourism attributes,the high integration of culture,business,tourism and education,and the creation of tourism atmosphere,in order to provide inspiration for the healthy,orderly and high-quality development of the Pearl River night tour.

关键词： Integration of culture and tourism The Pearl River night tour High-quality development Intangible cultural elements

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新形势下的农业农村经济发展方向

农业技术与装备 2010年第16期 41-42页

作者：杨连荣山西省大同市种子管理站 037006

市场需求对农业发展的影响越来越明显,在这种新形势下,确保农业农村经济可持续稳定发展,必须解决城乡居民收入差距,加快建设新农村,保护农村环境,发展现代农业,加大对"三农"的投入力度,扩大农业生产规模。

关键词：市场需求可持续发展新形势增收渠道

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玉米高产栽培实用技术

农业技术与装备 2008年第8期 47-48页

作者：杨连荣山西省大同市种子管理站 037006

玉米的高产离不开科学的栽培技术,从播种前到收获后的各个环节都不容忽视。为此,总结介绍了玉米高产栽培的6项实用技术,广泛推广,才能真正实现玉米高产。

关键词：玉米高产栽培实用技术合理管理

法治反腐的中国理论——习近平法治思想中的法治反腐理论研究

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中共中央党校（国家行政学院）学报 2024年第2期28卷 14-23页

作者：邓联荣中共湖南省委党校(湖南行政学院) 中国廉政法制研究会湖南省当代中国马克思主义研究中心省委党校(行政学院)分中心

法治反腐是新时代中国的重要选择与生动实践。习近平法治思想中的法治反腐理论内涵丰富,深刻回答了中国语境下“为什么要法治反腐”“什么是法治反腐”“用什么样的法治反腐”“怎么法治反腐”“法治反腐怎么样”等问题,指导新时代法治... 详细信息

法治反腐是新时代中国的重要选择与生动实践。习近平法治思想中的法治反腐理论内涵丰富,深刻回答了中国语境下“为什么要法治反腐”“什么是法治反腐”“用什么样的法治反腐”“怎么法治反腐”“法治反腐怎么样”等问题,指导新时代法治反腐实践取得了丰硕成果。习近平法治思想中的法治反腐理论是法治反腐的中国理论,集中体现了法治反腐的中国智慧,为发展中国特色社会主义法治反腐理论作出了重大原创性贡献。

关键词：习近平法治思想反腐败法治反腐制度反腐

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基于溃疡性结肠炎促炎细胞因子IL-8的白头翁汤提取工艺的优化

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黑龙江畜牧兽医 2021年第8期 124-127,154页

作者：杨连荣张丽杰张哲锋黑龙江中医药大学哈尔滨150040 葵花药业集团股份有限公司哈尔滨150200 黑龙江省农产品和兽药饲料技术鉴定站哈尔滨150069

为了对白头翁汤的提取工艺进行优化,试验以用三硝基苯磺酸(TNBS)诱导的溃疡性结肠炎模型小鼠为研究对象,选取提取时间、乙醇浓度、溶剂用量为考察因素,以小鼠病变结肠组织中白细胞介素8(IL-8)的含量为响应值,利用Box-Behnken响应面法对... 详细信息

为了对白头翁汤的提取工艺进行优化,试验以用三硝基苯磺酸(TNBS)诱导的溃疡性结肠炎模型小鼠为研究对象,选取提取时间、乙醇浓度、溶剂用量为考察因素,以小鼠病变结肠组织中白细胞介素8(IL-8)的含量为响应值,利用Box-Behnken响应面法对乙醇提取白头翁汤的提取工艺进行优化,并对最佳提取条件进行验证。结果表明:白头翁汤最佳提取条件为提取时间1.2 h,乙醇浓度72%,溶剂用量11倍。验证试验IL-8含量测量结果的平均值为3.62 ng/g,与预测值的偏差为2.26%,与预测值非常接近,偏差较小。说明将化学指标与能反映抗炎效果的免疫性指标结合进行综合评价,工艺的优化更有针对性,得出的试验结果更客观、合理。

关键词：溃疡性结肠炎白细胞介素8 Box-Behnken设计白头翁汤提取工艺响应面

瓦解与重构:IMF事件以来韩国电影发行业之观察

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当代电影 2024年第4期 117-127页

作者：臧连荣重庆师范大学文学院

如果说20世纪90年代之前,决定韩国电影业的是军政体制,那么,1997年金融危机后的IMF接管韩国经济则是改变韩国文化产业发展的重要事件,此后韩国电影发行业则由制度管控让渡给了新自由主义市场经济体制。本文以IMF事件为起点,将1998年以... 详细信息

如果说20世纪90年代之前,决定韩国电影业的是军政体制,那么,1997年金融危机后的IMF接管韩国经济则是改变韩国文化产业发展的重要事件,此后韩国电影发行业则由制度管控让渡给了新自由主义市场经济体制。本文以IMF事件为起点,将1998年以来的韩国电影发行业分为三个阶段予以观察:第一阶段(1998—2006)是制度和政策因素主导的90年代末反倾销到电影配额减半,充满了韩美政府间的博弈;第二阶段(2007—2019)是将“规制”主导让渡给“支援”,促成产业自觉垂直整合,同时充满了政府对企业的反垄断化特征;第三阶段(2020—2022)为全球新冠大流行下行业收缩,OTT主导的网络VOD的在线市场兴起,发行业靠市场倒逼完成自我重构。韩国电影发行业从规制到自觉,完成了传统结构的瓦解和新秩序的建立。在新秩序下,韩国文化产品的影响力遍及全球,同时也充满挑战。

关键词： IMF 韩国电影发行业瓦解与重构多样化 OTT

护理人员风险意识及护理风险相关因素调查分析

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中国护理管理 2008年第5期8卷 59-61页

作者：杨莲荣戴青梅潍坊市人民医院护理部山东省261041

目的:了解护理风险现状,探索护理风险发生的规律、特点和高危因素。方法:对30所医院的4957名医护人员进行问卷调查,建立数据库,所得资料运用SPSS11.0软件统计分析,采用Logistic回归分析、χ2检验,并建立风险重要性因素象限推导模型。结... 详细信息

目的:了解护理风险现状,探索护理风险发生的规律、特点和高危因素。方法:对30所医院的4957名医护人员进行问卷调查,建立数据库,所得资料运用SPSS11.0软件统计分析,采用Logistic回归分析、χ2检验,并建立风险重要性因素象限推导模型。结果:新职工及工作5年内人员为护理风险高危人群;外科、妇产科、小儿科、急诊科为护理风险的高危科室;管理制度、风险教育、规程执行等变量与风险发生呈负相关;职业保险、风险组织、风险教育等9项因素为优先解决的问题。结论:加强风险管理,完善职业保险是防范护理风险的关键和根本。

关键词：护理风险调查分析防御对策