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核因子κB和白细胞介素-6在放射性膀胱损伤中的表达及意义

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中国医科大学学报 2024年第4期53卷 332-336页

作者：阮绥鑫李良陈静锦州医科大学附属第一医院妇科辽宁锦州121000 锦州医科大学附属第三医院泌尿科辽宁锦州121000辽宁锦州121000 锦州医科大学附属第一医院日间化疗中心辽宁锦州121000

目的检测核因子κB(NF-κB)和白细胞介素-6(IL-6)在放射性膀胱损伤中的表达特征及其相关性。方法选择人输尿管上皮永生化细胞SV-HUC-1进行培养,分别应用5、10和15 Gy的X线照射2.、48和72.h,将未行照射的SV-HUC-1细胞作为正常对照组。CC... 详细信息

目的检测核因子κB(NF-κB)和白细胞介素-6(IL-6)在放射性膀胱损伤中的表达特征及其相关性。方法选择人输尿管上皮永生化细胞SV-HUC-1进行培养,分别应用5、10和15 Gy的X线照射2.、48和72.h,将未行照射的SV-HUC-1细胞作为正常对照组。CCK-8检测细胞增殖活性,实时定量PCR检测NF-κB和IL-6 mRNA的表达。将siRNA-NF-κB质粒转染至15 Gy X线照射72.h后的细胞株建立siRNA-NF-κB组(si-NF-κB组),将未转染质粒的15 Gy X线照射72.h后细胞株作为空白对照组,Western blotting检测IL-6蛋白的表达。将2.只雄性SD大鼠分为模型组(一次性给予2. Gy X线照射,建立放射性膀胱损伤大鼠模型)和对照组(不给予照射),每组10只,2.后处死大鼠,实时定量PCR检测膀胱组织中NF-κB和IL-6 mRNA的表达。结果SV-HUC-1细胞中,细胞增殖活性随着照射剂量和照射时间的增加而降低,NF-κB和IL-6 mRNA的表达随着照射剂量和照射时间的增加而增加。si-NF-κB组中IL-6的表达量明显低于空白对照组(P<0.05)。放射性膀胱损伤大鼠模型的膀胱病变组织中,NF-κB和IL-6 mRNA的表达明显高于对照组(P<0.05),NF-κB和IL-6 mRNA的表达呈正相关。结论X线对膀胱的损伤呈浓度和时间依赖性,病变组织中NF-κB和IL-6的表达升高,二者具有协同作用。

关键词：放射性膀胱损伤核因子κB 白细胞介素-6 炎性病变

Research perspective and prospective of additive manufacturing of biodegradable magnesium-based materials

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Journal of Magnesium and Alloys 2023年第5期11卷 1485-1504页

作者： Qingyun Fu Wenqi liang Jiaxin Huang Weihong jin Baisong Guo Ping Li Shulan Xu Paul K.Chu Zhentao Yu Center of Oral Implantology Stomatological HospitalSouthern Medical UniversityGuangzhou 510280China Institute of Advanced Wear&Corrosion Resistant and Functional Materials Jinan UniversityGuangzhou 510632China department of Physics Department of Materials Science and Engineeringand Department of Biomedical EngineeringCity University of Hong KongTat Chee AvenueKowloonHong KongChina

Biodegradable metals such as magnesium(Mg)and its alloys have attracted extensive attention in biomedical research due to their excellent mechanical properties and ***,traditional casting,extrusion,and commercial processing have limitations in manufacturing components with a complex shape/structure,and these processes may produce defects such as cavities and gas pores which can degrade the properties and usefulness of the *** to conventional techniques,additive manufacturing(AM)can be used to precisely control the geometry of workpieces made of different Mg-based materials with multiple geometric scales and produce desirable medical products for orthopedics,dentistry,and other ***,a detailed and thorough understanding of the raw materials,manufacturing processes,properties,and applications is required to foster the production of commercial Mg-based biomedical components by *** review summarizes recent advances and important issues pertaining to AM of Mg-based biomedical products and discusses future development and application trends.

关键词： Magnesium-based materials Additive manufacturing Wires and powders Biomedical metallic materials Medical devices

ONE　OF　MECHANISMS　FOR　CONJUGATE　SHEAR　ANGLE＇S　TRANSFORM　FROM　ACUTE　TO　OBTUSE　IN　A　COMPRESSEDRIGIDBLOCK

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Scientia Geologica Sinica 1994年第2期 175-182页

作者： liang Haihua Zhao Yonghong Hou Jianjun Zheng Wentao Bat Taixu and Dong Wenzhong (department of Geology, Peking {2., Beijing 100871)

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How about the reporting quality of case reports in nursing field?

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World Journal of Clinical Cases 2019年第21期7卷 3505-3516页

作者： ke-Lu Yang Cun-Cun Lu Yue Sun Yi-Tong Cai Bo Wang Yi Shang jin-Hui Tian Evidence-Based Nursing Center School of NursingLanzhou UniversityLanzhou 730000Gansu ProvinceChina Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000Gansu ProvinceChina Gansu Province Hospital Rehabilitation Center Lanzhou 730000Gansu ProvinceChina Lanzhou university Second Hospital Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND As a significantly important part of clinical practice,the professional nursing process can be advanced in many *** the fact that case reports are regarded to be of a lower quality grade in the hierarchy of evidence,one of the principles of evidence-based medicine is that decision-making should be based on a systematic summary of ***,the evidence on the reporting characteristics of case reports in the nursing field is *** To use the CARE guidelines to assess reporting quality and factors influencing the quality of case reports in the nursing *** Nursing science citation indexed(SCI-indexed)journals were identified from the professional *** of the identified journals was searched on their website for articles published before December ***-one sub-items on the CARE checklist were recorded as“YES”,“PARTLY”,or“NO”according to information reported by the included *** responses were assigned corresponding scores of 1,0.5,and 0,*** overall score was the sum of the 2. sub-items and was defined as“high”(more than 15),“medium”(10.5 to 14.5),and“low”(less than 10).The means,standard deviations,odds ratios(OR),and the associated 95%confidence interval(CI)were determined using Stata 12.0 *** Ultimately,184 case reports from 16 SCI-indexed journals were identified,with overall scores ranging from 6.5 to 18(mean=13.6±2.3).Of the included case reports,10.3%were regarded low-quality,52.7%were considered middle-quality,and 37%were regarded *** were statistical differences in the mean overall scores of the included case reports with funding versus those without funding(14.2.1.7 vs 13.6±2.4,respectively;P=0.4456)and journal impact factor1.8 versus impact factor≥1.8(13.3±2.3 vs 13.6±2.4,respectively;P=0.4977).Five items from the CARE guidelines,5a(Patient),6(Clinical findings),8c(Diagnostic reasoning),9(Therapeutic intervention),and 11d(The main take-away lessons)were

关键词： Systematic review Case reports Case report guidelines Nursing Reporting quality Science citation indexed journals

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初唐薛元超门人群体的文学活动及功绩

湖南工程学院学报（社会科学版） 2024年第1期34卷 70-75页

作者：梁亚楠湖南科技大学人文学院湖南湘潭411201

薛元超在唐高宗上元、仪凤中担任宰相的几年间,主持门下省弘文馆工作,将十多位文士引入馆中,频繁开展文馆活动,促成了以他为中心的文人群体的形成,不仅创造了文学实绩,提升了创作水平,还促进了高宗朝尚雅的文学风尚的形成,并为武后、中... 详细信息

薛元超在唐高宗上元、仪凤中担任宰相的几年间,主持门下省弘文馆工作,将十多位文士引入馆中,频繁开展文馆活动,促成了以他为中心的文人群体的形成,不仅创造了文学实绩,提升了创作水平,还促进了高宗朝尚雅的文学风尚的形成,并为武后、中宗朝培养了文学人才。由于群体主要为宫廷诗人,作诗重视形式和技巧的探索,所以他们的创作和理论研究为律体诗在武后、中宗朝的定型奠定了基础。

关键词：薛元超门人群体文学活动

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橡碗栲胶浸提工艺参数优化及分析

西安工业大学学报 2011年第7期31卷 634-637页

作者：张国春王书民任有良李正军商洛学院化学与化学工程系商洛726000 商洛栲胶厂商洛726000

研究橡碗栲胶浸提过程中各因素对浸提效率的影响,对橡碗栲胶实际生产的工艺参数进行优化和分析.采用单因素循环法及压力六罐组逆流浸提的方式研究了不同浸提压力、浸提温度、浸提时间、原料粒度和不同浸提水质下橡碗栲胶的浸提情况.研... 详细信息

研究橡碗栲胶浸提过程中各因素对浸提效率的影响,对橡碗栲胶实际生产的工艺参数进行优化和分析.采用单因素循环法及压力六罐组逆流浸提的方式研究了不同浸提压力、浸提温度、浸提时间、原料粒度和不同浸提水质下橡碗栲胶的浸提情况.研究结果表明:橡碗栲胶浸提的最优工艺参数浸提压力为0.2.MPa;浸提温度首罐为70℃,尾罐为95℃;浸提时间80min/步;原料粒度5mm;浸提水质pH值为6左右的软水;出液系数为400%.

关键词：橡碗栲胶浸提工艺参数

Air tamponade and without heavy liquid usage in pars plana vitrectomy for rhegmatogenous retinal detachment repair

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International Journal of Ophthalmology(English edition) 2018年第11期11卷 1779-1783页

作者： Zhong Lin Qi-Hua liang ke Lin Zhi-Xiang Hu Tian-Yu Chen Rong-Han Wu Nived Moonasar The Eye Hospital School of Ophthalmology and Optometry Wenzhou Medical University department of Ophthalmology University of the West Indies

AIM： To report the results of rhegmatogenous retinal detachment（RRD） repair after pars plana vitrectomy（PPV） without operative use of heavy liquid, and utilizing air tamponade in selected ***： RRD patients without severity of proliferative vitreoretinopathy C2.or more underwent PPV without operative use of heavy liquid, and utilizing air tamponade were consecutively enrolled. Alternative postoperative facedown position or lateral position was required for 3-5 ***： Totally 36 eyes of 36 patients（2. males, 66.7%） aged 53.8±10.9 y underwent this modified surgery. The mean number of retinal break was 2.1.1.3. Most of the eyes（2., 80.6%） had retinal detachment involving more than one quadrant. Twenty-two（61.1%） eyes with cataract had combined phacoemulsification and intraocular lens implantation. The mean follow up time was 4.6±1.8 mo. Two eyes with retinal redetachment underwent a second retinal repair surgery with silicone oil tamponade, yielding the primary reattachment rate to 94.4%（34/36）. Six（16.7%） eyes had intraocular pressure higher than 2. mm Hg. The visual acuity（logMAR） improved from 0.98±0.74 preoperatively to 0.52.0.31 postoperatively（P〈0.001）. CONCLUSION： The success rate of this modified retinal repair surgery is comparable with traditional surgery. This technique can be considered for certain retinal detachment patients, since its apparent advantages included lower surgical complications, reduced surgery expenditure, shorter time for postoperative facedown position, and avoiding silicone oil removal surgery.

关键词： air heavy liquid rhegmatogenous retinal detachment pars plana vitrectomy

Polymerization of Norbornene via an Iron-Based Complex/MAO Catalytic System

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Chemical Research in Chinese Universities 2002年第4期18卷 462-465页

作者： MI Xia MA Zhi YAN Wei-dong LIU Yuan-xia WANG Hang ke Yu-cai HU You-liang State key Lab of Engineering Plastics Center for Molecular ScienceBeijing Laboratory of CatalysisCNPC Key Laboratory of CatalysisInstitute of ChemistryChinese Academy of SciencesBeijing 100080P.R.China Graduate School of Chinese Academy of Sciences Beijing 100080 Institute of Polymer Science and Engineering Hebei University of TechnologyTianjin 300130P.R.China

Polynorbornenes were synthesized in the presence of an iron based catalyst, 2.6-bis[1-(2.6-diisopropyl-phenylimino)ethyl]pyridine iron(Ⅱ) dichloride. The FTIR, 1H NMR and 13C NMR analysis results revealed that the structure of the obtained polynorbornenes consisted of vinyl addition polymer substructures without any ring-opening structures. The polymers were amorphous with a short-range order, displayed in the WAXD(wide angle X-ray diffraction) diagrams. The glass transition temperatures ranged from 2.0 to 400 ℃. The effects of the polymerization reaction conditions, such as Al/Fe molar ratio and toluene/CH_2.l_2.volume ratio, on the activity, intrinsic viscosity and T_g were also studied.

关键词： Polynorbornene Iron-based complex Vinyl addition polymer Short-range order Norbornene polymerization

Kloosterman sums with multiplicative coefficients

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Science China mathematics 2016年第4期59卷 653-660页

作者： GONG ke JIA ChaoHua department of mathematics Henan University Institute of mathematics Academy of Mathematics and Systems ScienceChinese Academy of Sciences Hua Loo-keng key Laboratory of {2. Chinese Academy of Sciences

Let f(n)be a multiplicative function satisfying |f(n)|≤1,q(≤N^2.be a positive integer and a be an integer with(a,q)= *** this paper,we shall prove that ∑n≤N(n,q)=1f(n)e(an/q)■(1/2.(τ(q)/q)N loglog(6N)+ q^(1/4+ε/2.N^(2.1.(log(6N))^(1/2.+N/(1/2.(loglog(6N)),where n is the multiplicative inverse of n such that nn ≡ 1(mod q),e(x)= exp(2.ix),and τ(·)is the divisor function.

关键词： Kloosterman sum multiplicative function finite version of Vinogradov's inequality