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Bioinformatic Analysis of Structural Proteins of Paramyxovirus Tianjin Strain

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Virologica Sinica 2008年第4期23卷 279-286页

作者： li-ying SHI Mei li Xiao-mian li li-jun YUAN Qing wang Department of Microbiology the College of Basic Medical Science Tianjin Medical University Tianjin 300070 China

The amino acid sequences of the NP, P, M, F, HN and L proteins of the paramyxovirus Tianjin strain were analyzed by using the bioinformatics methods. Phylogenetic analysis based on 6 structural proteins among the Tianjin strain and 25 paramyxoviruses showed that the Tianjin strain belonged to the genus Respirovirus, in the subfamily Paramyxovirinae, and was most closely related to Sendai virus (SeV). Phylogenetic analysis with 14 known SeVs showed that Tianjin strain represented a new evolutionary lineage. Similarities comparisons indicated that Tianjin strain P protein was poorly conserved, sharing only 78.7% - 91.9% amino acid identity with the known SeVs, while the L protein was the most conserved, having 96.0% - 98.0% amino acid identity with the known SeVs. Alignments of amino acid sequences of 6 structural proteins clearly showed that Tianjin strain possessed many unique amino acid substitutions in their protein sequences, 15 in NP, 29 in P, 6 in M, 13 in F, 18 in HN, and 29 in L. These results revealed that Tianjin strain was most likely a new genotype of SeV. The presence of unique amino acid substitutions suggests that Tianjin strain maybe has a significant difference in biological, pathological, immunological, or epidemiological characteristics from the known SeVs.

关键词： Sendai virus Structural proteins Bioinformatic analysis

Experimental Study of Temperature Control Based on Composite Phase Change Materials during Charging and Discharging of Battery

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Journal of Thermal Science 2024年第2期33卷 578-590页

作者： li Xiaolin wang jun CAO Wenxiang ZHANG Xuesong School of Automotive and Traffic Engineering Jiangsu UniversityZhenjiang212013China

This study is to utilize the heat-absorbing and releasing capabilities of phase change materials(PCM)to regulate the surface temperature fluctuations of batteries during charging and *** goal is to keep the battery within the optimal operating temperature *** impact of PCM thickness and phase change temperature on battery temperature is investigated by encircling a cylindrical battery with a PCM *** improve the thermal conductivity of PCM,expanded graphite(EG) is added to make a composite phase change material(CPCM),and the effects of various EG mass ratios on battery surface temperature and CPCM utilization level are *** findings indicate that increasing PCM thickness effectively extends temperature control time,but its impact is *** difference in phase change temperature of PCM controls the battery temperature in different temperature *** phase change temperatures are unsuitable for controlling battery temperature in high temperature *** addition of EG enhances the thermal conductivity of PCM,leading to further control of battery *** results show that the addition of 6%(mass ratio) EG to CPCM extends the effective temperature control time by 11 min and improves by 28% compared to a single *** CPCM utilization is also more satisfactory and achieved a balance between heat storage and thermal conductivity in a battery thermal management system(BTMS) based on PCM.

关键词： phase change material expanded graphite thermal management system effective control time

Optimal Model Average Prediction in Orthogonal Kriging Models

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Journal of Systems Science & Complexity 2024年第3期37卷 1080-1099页

作者： wang jun HE Jiabei liANG Hua li Xinmin School of Mathematics and Statistics Qingdao UniversityQingdao 266071China Department of Statistics George Washington UniversityWashington DC 20052USA

The main objective of this paper is to consider model averaging methods for kriging *** paper proposes a Mallows model averaging procedure for the orthogonal kriging model and demonstrate the asymptotic optimality of the model averaging estimators in terms of mean square *** studies are conducted to evaluate the performance of the proposed method and compare it with the competitors to demonstrate its *** authors also analyse a real dataset for an illustration.

关键词： Asymptotic optimality Mallows criterion optimal model averaging orthogonal kriging model

Time-history performance optimization of flapping wing motion using a deep learning based prediction model

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Chinese Journal of Aeronautics 2024年第5期37卷 317-331页

作者： Tianqi wang liu liU jun li lifang ZENG School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310027China Huanjiang Laboratory Zhuji 311800China

Flapping Wing Micro Aerial Vehicles(FWMAVs)have caused great concern in various fields because of their high efficiency and *** wing motion is a very important factor that affects the performance of the aircraft,and previous works have always focused on the time-averaged performance ***,the time-history performance is equally important in the design of motion mechanism and flight control *** this paper,a time-history performance optimization framework based on deep learning and multi-island genetic algorithm is presented,which is designed in order to obtain the optimal two-dimensional flapping wing ***,the training dataset for deep learning neural network is constructed based on a validated computational fluid dynamics *** aerodynamic surrogate model for flapping wing is obtained after the convergence of *** surrogate model is tested and proved to be able to accurately and quickly predict the time-history curves of lift,thrust and ***,the optimization framework is used to optimize the flapping wing motion in two specific cases,in which the optimized propulsive efficiencies have been improved by over 40%compared with the ***,a dimensionless parameter C_(variation)is proposed to describe the variation of the time-history characteristics,and it is found that C_(variation)of lift varies significantly even under close time-averaged *** the importance of time-history performance in practical applications,the optimization that integrates the propulsion efficiency as well as C_(variation)is carried *** final optimal flapping wing motion balances good time-averaged and time-history performance.

关键词： FWMAV Flapping wing motion Deep learning Unsteady aerodynamic performance Optimization Time-history curve

Sonographic features of duodenal lipomas in eight clinicopathologically diagnosed patients

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World Journal of Gastroenterology 2011年第23期17卷 2855-2859页

作者： Hong-Tan Chen Guo-Qiang Xu li-jun wang Yi-Peng Chen You-Ming li Department of Gastroenterology The First Affiliated Hospi-tal Medical School of Zhejiang University Hangzhou 310003Zhejiang Province China Department of Pathology The First AffiliatedHospital Medical School of Zhejiang University Hangzhou310003 Zhejiang Province China

AIM:To investigate the sonographic features and diagnostic value of endoscopic ultrasonography (EUS) for duodenal lipomas (DLs).METHODS:A total of eight consecutive patients with DL diagnosed pathologically were included in the *** EUS expert reviewed the ultrasonic images for all lesions,including the original layer of the duodenal wall,the echo intensity and the echo *** size of the lesions and the perifocal structures were also *** diagnosis by EUS was compared with the histological ***:Using routine endoscopy,only one case was correctly diagnosed as *** cases were classified as submucosal tumors,and three cases were mistaken for stromal *** tumors appeared as round or oval intensive hyperechoic lesions with distinct anterior borders that originated from the submucosal layer on *** ranged from 8 to 36 mm in size,with an average size of 16 *** echogenicity was seen in all cases except one that had a tubular structure inside the *** attenuation was observed only in the area behind the tumors in five cases,and it was observed both inside and behind the tumors in three cases in which the posterior border was obscure or *** (87.5%) cases were correctly diagnosed as DL,and one (12.5%) was mistaken as Brunner's gland adenoma by ***,all tumors originated from the submucosal layer and consisted of mature fat cells without *** the fat cells,there was a small amount of thick-wall vessels infiltrating the lymphocytes,and abundant fibrous connective ***:On EUS,DL is featured as an intensive homogeneous hyperechoic submucosal lesion with marked echo attenuation and without involvement of the mucosa.

关键词： Duodenum lipoma Endoscopic ultraso-nography Hyperecho Echo attenuation

Thermodynamics of Solvent Extraction of Rare and Scattered Metal-Indium with Diethylhexylmonothiophosphoric Acid

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Chemical Research in Chinese Universities 2006年第1期22卷 111-113页

作者： liU Xing-zhi ZANG Shu-liang FANG Da-wei li jun wang Lu-ning Institute of Chemical Science and Engineering Liaoning University Shenyang 110036 P. R. China

The thermodynamics of extracting In（ Ⅲ） with diethylhexylmonothiophosphoric acid as an extractant in a H2SO4 system is reported. The equilibrium molalities of In^3＋ ions were measured at a high acidity and ionic strengths varying from 0. 1 to 2.0 mol/kg in an aqueous phase containing Na2SO4 as the supporting electrolyte. The values of the standard extraction constant K^0 at various temperatures were obtained by the methods of extrapolation and polynomial approximation. The equation lgK^0 = - 51.95 - 5.93 × 10^3/T ＋ 6. 15 × 10^-2 T was also obtained and the thermodynamic quantities for the extraction process were calculated.

关键词： Extraction Indium Diethylhexylmonothiophosphoric acid Thermodynamics

Real-time frequency transfer system over ground-to-satellite link based on carrier-phase compensation at 10-16 level

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Chinese Physics B 2021年第8期30卷 260-268页

作者： Hui-Jian liang Shi-Guang wang Yu Bai Si-Chen Sun li-jun wang Department of Electronic Engineering Tsinghua UniversityBeijing 100084China State Key Laboratory of Precision Measurement Technology and Instruments Tsinghua UniversityBeijing 100084China Department of Precision Instruments Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China

We demonstrate a novel and stable frequency transfer scheme over ground-to-satellite link based on real-time carrier-phase detection and *** performed a zero-baseline measurement with the designed system,an uninterrupted frequency standard signal is recovered in the reception station without additional post-correction of delay error caused in the route,which is because the phase error of the entire route is tracked and compensated continuously in *** achieve this goal,we employed two carriers in the system and the differential signal is transferred in order to eliminate the instability results from the local oscillator at the satellite transponder as well as the common-mode noise induced in the transfer route and microwave *** stability of 3×10^(-16) with an integration time of 1 day was achieved and the time fluctuation during one day was measured to be about±20 *** sources and possible solutions are *** zero-baseline method shows a promising result for real-time satellite-based time and frequency transfer and deserves further research to find whether it works between long-baseline stations.

关键词： frequency transfer ground-to-satellite link carrier-phase compensation

Karyotyping of Brassica napus L. Based on C0t-1 DNA Banding by Fluorescence In Situ Hybridization

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Journal of Integrative Plant Biology 2005年第12期47卷 1479-1484页

作者： Wen-Hui WEI Wan-Peng ZHAO li-jun wang Bo CHEN Yun-Chang li Yun-Chun SONG Institute of Oil Crops Chinese Academy of Agricultural Sciences Wuhan 430062 China College of life Sciences Xinyang Normal University Xinyang 464000 China Key Laboratory of Ministry of Education for Plant Developmental Biology College of Life Sciences Wuhan University Wuhan 430072 China

In order to precisely recognize and karyotype Brassica napus L. chromosomes, C0t-1 DNA was extracted from its genomic DNA, labeled with biotin-1 1-dUTP and in situ hybridized. The hybridized locations were detected by Cy3-conjugated streptavidin. Specific fluorescence in situ hybridization （FISH） signal bands were detected on all individual chromosome pairs. Each chromosome pair showed specific banding patterns. The B. napus karyotype has been constructed, for the first time, on the basis of both Cot-1 DNA FISH banding patterns and chromosome morphology.

关键词： Brassica napus C0t-1 DNA chromosome banding fluorescence in situ hybridization(FISH) karyotyping.

Enhanced Flexoelectric Response from Functionally Gradient Electrets Undergoing Crumpling Deformation

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Acta Mechanica Solida Sinica 2024年第4期37卷 541-554页

作者： Jianhua Ma Jinrui Xu jun li Binglei wang Department of Engineering Mechanics Shandong UniversityJinan250061China

Non-uniform deformation of the dielectric subjected to external forces can induce the flexoelectric effect, a phenomenon that couples electrical polarization to strain gradients. However, limited by the size effects, flexoelectricity is not significant at the macroscale and only becomes catchable at the microscale and nanoscale. In recent work, we obtained a considerable flexoelectric-like response by crumpling the dielectric embedded with charges, i.e., the electret, which significantly improved the flexoelectric effect at the macroscale. In this work, we further optimize the macroscopic performance of the flexoelectric response by applying gradient treatment to the electret films. Specifically, we analytically derive the electromechanical coupling of crumpled electret films with gradients of different thicknesses, charge densities, and Young’s moduli as key design variables. It is shown that the gradient-oriented electret film can be tuned to nearly five times that of a uniform electret film.

关键词： Functionally gradient electret Size effects Crumpling Flexoelectric-like response