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Dendrobium nobile protects against ovalbumin-induced allergic rhinitis by regulating intestinal flora and suppressing lung inflammation

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Chinese Journal of Natural Medicines 2022年第6期20卷 443-457页

作者： DUAN Fei-Peng li yi-sheng HU Tian-Yong PAN Xin-Quan MA Fang FENG Yue QIU Shu-Qi ZHENG yi-Qing Institute of Otolaryngology Institute of Hearing and Speech of Sun Yat-sen UniversitySun Yat-sen Me-morial HospitalSun Yat-sen UniversityGuangzhou 510520China Department of Otolaryngology Longgang E.N.T hospital&Shenzhen Key Laboratory of E.N.TInstitute of E.N.TShenzhen 518172China

Antibiotic exposure-induced dysbiosis of the intestinal flora increases the risk of developing allergic ***,regulating the balance of intestinal flora may be useful for preventing and treating allergic ***,the underlying mechanism is *** nobile(Shihu)exhibits anti-inflammatory and immune ***,in this study,we investigated the mechanism via which Shihu may improve allergic *** models of allergic rhinitis with intestinal flora dysbiosis(Model-D,antibiotics induce intestinal flora dysbiosis with ovalbumin-induced allergy)and normal intestinal flora with allergic rhinitis(Model-N,ovalbumin-induced allergy)were *** effect of Shihu on intestinal flora and inflammation caused during allergic rhinitis were *** symptoms,infiltration of hematoxylin and eosin in the lungs and nose,and the release of various factors[interleukin(IL)-2,IL-4,IFN-y,IL-6,IL-10,and IL-17]in the lungs were *** results indicate that intestinal flora dysbiosis exacerbated lung and nose inflammation in allergic ***,treatment with the Shihu extract effectively reversed these ***,the Shihu extract inhibited the PI3K/AXT/mTOR pathway and increased the level of Forkhead box protein in the ***,the Shihu extract reversed intestinal flora dysbiosis at the phylum and genus levels and improved regulator T cell ***,in the Model-D group,the Shihu extract inhibited the decrease in the diversity and abundance of the intestinal *** was performed to determine which intestinal flora was positively correlated with Treg differentiation using Spearman5 s correlation *** conclusion,we showed that Shihu extract restored the balance in intestinal flora and ameliorated inflammation in the lungs of allergic rhinitis mice and predicted a therapeutic new approach using Traditional Chinese Medicine to improve allergic rhinitis.

关键词： Dendrobium nobile(Shihu) Allergic rhinitis Intestinal flora Regulator T cell Inflammation

Symmetric Workpiece Localization Algorithms: Convergence and Improvements

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自动化学报 2006年第3期32卷 428-432页

作者： CHEN Shan-Yong li sheng-yi DAI yi-Fan School of Mechatronics Engineering and Automation National University of Defense Technology Changsha 410073

Symmetric workpiece localization algorithms combine alternating optimization and linearization. The iterative variables are partitioned into two groups. Then simple optimization approaches can be employed for each subset of variables, where optimization of configuration variables is simplified as a linear least-squares problem (LSP). Convergence of current symmetric localization algorithms is discussed firstly. It is shown that simply taking the solution of the LSP as start of the next iteration may result in divergence or incorrect convergence. Therefore in our enhanced algorithms, line search is performed along the solution of the LSP in order to find a better point reducing the value of objective function. We choose this point as start of the next iteration. Better convergence is verified by numerical simulation. Besides, imposing boundary constraints on the LSP proves to be another efficient way.

关键词：对称加工件局限性线性搜索收敛性

Defect-free surface of quartz glass polished in elastic mode by chemical impact reaction

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Journal of Central South University 2014年第12期21卷 4438-4444页

作者：彭文强关朝亮李圣怡 College of Mechatronics and Automation National University of Defense Technology Hunan Key Laboratory of Ultra-precision Machining Technology

Removal of brittle materials in the brittle or ductile mode inevitably causes damaged or strained surface layers containing cracks, scratches or dislocations. Within elastic deformation, the arrangement of each atom can be recovered back to its original position without any defects introduced. Based on surface hydroxylation and chemisorption theory, material removal mechanism of quartz glass in the elastic mode is analyzed to obtain defect-free surface. Elastic contact condition between nanoparticle and quartz glass surface is confirmed from the Hertz contact theory model. Atoms on the quartz glass surface are removed by chemical bond generated by impact reaction in the elastic mode, so no defects are generated without mechanical process. Experiment was conducted on a numerically controlled system for nanoparticle jet polishing, and one flat quartz glass was polished in the elastic mode. Results show that scratches on the sample surface are completely removed away with no mechanical defects introduced, and microroughness(Ra) is decreased from 1.23 nm to 0.47 nm. Functional group Ce — O — Si on ceria nanoparticles after polishing was detected directly and indirectly by FTIR, XRD and XPS spectra analysis from which the chemical impact reaction is validated.

关键词： defect-free surface chemical impact reaction nanoparticle jet polishing elastic mode

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基于CAD模型的工件定位算法研究

自动化学报 2001年第1期27卷 9-17页

作者：刘阳李圣怡戴一帆国防科学技术大学机电工程与自动化学院长沙410073

介绍了基于 CAD模型的工件定位方法 ,利用代数学工具描述了三类工件定位问题 ,给出了求解算法 ;从收敛性、精度、效率等方面出发进一步分析了算法的性能 ,对定位算法进行了效率和收敛性方面的优化 ;给出了仿真实例 .

关键词：工件定位欧几里德变换定位算法计算机辅助设计 CAD

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滤波器组框架理论及其在图信号处理中的应用

控制与决策 2018年第5期33卷 866-878页

作者：柴利易静文盛玉霞武汉科技大学冶金自动化与检测技术教育部工程研究中心武汉430081

滤波器组框架理论是应用数学、信号处理、图像处理和数字通信等领域的重要问题之一,对滤波器组框架的分析和设计问题进行研究有着重要的科学意义和应用前景.近年来,随着高维非规则化数据信息大量涌现,很多学者开始研究图信号处理的滤波... 详细信息

滤波器组框架理论是应用数学、信号处理、图像处理和数字通信等领域的重要问题之一,对滤波器组框架的分析和设计问题进行研究有着重要的科学意义和应用前景.近年来,随着高维非规则化数据信息大量涌现,很多学者开始研究图信号处理的滤波器组方法.因此对滤波器组框架理论及其在图信号处理中的应用进行了综述研究.首先对传统滤波器组框架理论的基础知识进行概述,总结滤波器组框架分析与设计方法;然后重点介绍两类图信号处理架构以及图滤波器组的最新研究成果;最后对未来的研究进行展望.

关键词：滤波器组框架理论多采样率图信号图滤波器优化设计

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自动计算NURBS初始权因子的方法

航空学报 2001年第2期22卷 184-186页

作者：王兴波李圣怡国防科技大学机电工程与自动化学院湖南长沙410073

通过对 NURBS曲线权因子几何属性的深入分析 ,给出了一个直观、简洁和客观计算权因子的一般方法 ;在此基础上 ,提出了利用线性插值法和嵌入 ANN算法的自动计算 NURBS权因子的具体方法。根据NURBS控制多边形的形状以及曲线的形状约束条... 详细信息

通过对 NURBS曲线权因子几何属性的深入分析 ,给出了一个直观、简洁和客观计算权因子的一般方法 ;在此基础上 ,提出了利用线性插值法和嵌入 ANN算法的自动计算 NURBS权因子的具体方法。根据NURBS控制多边形的形状以及曲线的形状约束条件 ,自动计算出 NURBS曲线的一组初始权因子。

关键词： NURBS曲线曲面初始权因子 CAD/CAM 计算方法线性插值人工神经网络

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一种新型控制器的设计方法

控制与决策 2005年第4期20卷 471-473,477页

作者：任永平李圣怡国防科技大学机电工程研究所湖南长沙410073

提出一种新的控制器设计方法.该方法利用相平面上控制曲面与电容板极间的场强在变化上的相似性,以构造电容板极间场强的方式来设计控制器,通过调节板极电压和场强的构造系数,可达到调节控制器的目的.该控制器具有物理意义清晰,可灵活调... 详细信息

提出一种新的控制器设计方法.该方法利用相平面上控制曲面与电容板极间的场强在变化上的相似性,以构造电容板极间场强的方式来设计控制器,通过调节板极电压和场强的构造系数,可达到调节控制器的目的.该控制器具有物理意义清晰,可灵活调节控制强度等优点.

关键词：控制器电容场强变增益

High-throughput screening of CO_(2) cycloaddition MOF catalyst with an explainable machine learning model

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Green Energy & Environment 2025年第1期10卷 132-138页

作者： Xuefeng Bai yi li Yabo Xie Qiancheng Chen Xin Zhang Jian-Rong li Beijing Key Laboratory for Green Catalysis and Separation and Department of Chemical Engineering College of Materials Science&EngineeringBeijing University of TechnologyBeijing100124China

The high porosity and tunable chemical functionality of metal-organic frameworks(MOFs)make it a promising catalyst design ***-throughput screening of catalytic performance is feasible since the large MOF structure database is *** this study,we report a machine learning model for high-throughput screening of MOF catalysts for the CO_(2) cycloaddition *** descriptors for model training were judiciously chosen according to the reaction mechanism,which leads to high accuracy up to 97%for the 75%quantile of the training set as the classification *** feature contribution was further evaluated with SHAP and PDP analysis to provide a certain physical understanding.12,415 hypothetical MOF structures and 100 reported MOFs were evaluated under 100℃ and 1 bar within one day using the model,and 239 potentially efficient catalysts were *** them,MOF-76(Y)achieved the top performance experimentally among reported MOFs,in good agreement with the prediction.

关键词： Metal-organic frameworks High-throughput screening Machine learning Explainable model CO_(2)cycloaddition

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磁流变抛光工艺参数的正交实验分析

光学技术 2006年第6期32卷 886-888,892页

作者：彭小强戴一帆李圣怡国防科技大学机电工程与自动化学院长沙410073

对利用自行配制的水基磁流变抛光液和磁流变抛光实验样机进行了以抛光去除效率和表面粗糙度为考核指标的工艺实验。应用正交试验方法分析了磁流变抛光中主要工艺参数(磁场强度、抛光粉浓度、抛光盘的转速、抛光盘与工件间的间隙)对抛光... 详细信息

对利用自行配制的水基磁流变抛光液和磁流变抛光实验样机进行了以抛光去除效率和表面粗糙度为考核指标的工艺实验。应用正交试验方法分析了磁流变抛光中主要工艺参数(磁场强度、抛光粉浓度、抛光盘的转速、抛光盘与工件间的间隙)对抛光去除效率和表面粗糙度的影响规律,并结合磁流变抛光机理对其进行了分析。根据实验结果对工艺参数进行了优化。

关键词：磁流变抛光正交试验抛光效率表面粗糙度