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Variations of opal accumulation rates and paleoproductivity over the past 12 Ma at ODP Site 1143, southern South China Sea

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Chinese Science Bulletin 2002年第7期47卷 596-598页

作者： li jianru Wang Rujian li Baohua Laboratory of Marine Geology MEOTongji University200092ShanghaiChina Nanjing Institute of Geology and Paleontology Chinese Academy of Sciences210008NanjingChina

The biogenic silica analysis was performed on 463 samples from ODP 184 Site 1143, the southern South China Sea. The results show that the opal content and MAR evidently increased between 12.3 and 5.7 Ma, which was contemporary with the high carbonate and total MARs, reflecting the high biogenic productivity in the late Miocene. This demonstrates the occurrence of the late Miocene 'Biogenic Bloom Event' in the southern South China Sea, corresponding to the late Miocene-early Pliocene 'Biogenic Bloom Event' in the Indian-Pacific Ocean. The increases of opal content and MAR after the middle Pleistocene (about 0.7 Ma) is inferred to result from the enhanced upwelling and nutrient supply, which was induced by the intensified monsoon circulation after the 'Mid-Pleistocene Revolution'.

关键词： opal MAR biogenic productivity Biogenic Bloom Event late Miocene South China Sea.

Temporal and spatial evolution of a deep-reaching anticyclonic eddy in the South China Sea

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Science China Earth Sciences 2019年第6期62卷 1002-1023页

作者： Meng WANG Yanwei ZHANG Zhifei liU Yulong ZHAO jianru li State Key Laboratory of Marine Geology Tongji University

The temporal and spatial evolution of a deep-reaching anticyclonic eddy(AE) is studied using a combination of satellite measurements, moored observations and ocean model reanalysis data in the South China Sea(SCS). Three evolutionary stages in eddy's lifecycle are identified from changes in eddy dynamical characteristics estimated from satellite altimetry: birth(22 days), growth(64 days), and decay(47 days). Similar patterns are also distinguished from dynamic signals in ***, flows reversal and upwelling of cold water below 1500 m were captured by the in-situ records when this energetic,highly nonlinear and long-lived(over 19 weeks) AE passed by our mooring position. Its detailed vertical structure is examined through temperature anomalies, vertical shear of horizontal velocities, and horizontal streamlines estimated from ocean model reanalysis data. Results from the model reveal a mesoscale AE with first-mode baroclinic structure: a bowl-shaped anticyclonic flow in the upper ocean connected to a slant-cylinder cyclonic flow at depth, with a transition layer at depths between 400 and 700 m. It is in good agreement with moored observations but showing a shallower transition depth, suggesting a slight deficiency in the model due to limited deep-sea observations. Last, we estimate eddy heat transport at different depths and stages along the AE's path based on the model data. The result reveals that pronounced heat fluxes occur during growth stage(depths 700–1500 m).Dynamical characteristics suggest that the vertical structure and temporal evolution of the eddy play significant roles in basinscale movement and heat transferring. Considering that mesoscale eddies are ubiquitous in the SCS, our results support a recently-proposed mechanism, whereby upper ocean flows produce changes in the deep-sea circulation, potentially influencing boundary l

关键词： Deep-reaching mesoscale eddy Evolution HYCOM The South China Sea

Changes in sea surface temperature in western South China Sea over the past 450 ka

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Chinese Science Bulletin 2009年第18期54卷 3335-3343页

作者： li li WANG Hui li jianru ZHAO MeiXun WANG PinXian State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China

Sea surface temperature over the past 450 ka was obtained by the unsaturation of molecular fossil-long chain alkenone with a resolution of about 1 ka from the western South China Sea. This is the longest temperature profile in the South China Sea at such high resolution. The U3k7′-SST results revealed similar glacial-interglacial cycles as the δ18O profile of planktonic foraminifera, with SST variability of 23―25.5℃ for glacial and 25―28℃ for interglacial periods. The highest SST (28.4℃) was recorded at MIS5.5 and lowest SST (22.6℃) during MIS2. The SST record preceded the planktonic foraminiferal δ18O on five glacial-interglacial transitions. Comparison of temperature records from the Southern and Northern Hemispheres indicated a more Southern Hemisphere-like pattern for the temperature variation in the SCS. Strong precession and semiprecession signals in the spectra of our SST record manifest the tropical phenomena.

关键词：华南西部海表温度中国浮游有孔虫海温变化海上间冰期表面温度

Dynamic control on grain-size distribution of terrigenous sediments in the western South China Sea:Implication for East Asian monsoon evolution

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Chinese Science Bulletin 2008年第10期53卷 1533-1543页

作者： CHEN GuoCheng ZHENG HongBo li jianru XIE Xin MEI Xi State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China

High-resolution oxygen isotope stratigraphy of Core MD05-2901, which is located off eastern Vietnam in the western South China Sea (SCS), was established and indicated that the core spans a time period of the past 450 ka. Based on the bulk density, fractional porosity and lithogenic content of the sedi-ments, terrigenous mass accumulation rate (TMAR) was obtained, which is 4.9―6.0 g cm?2 ka?1 on average during interglacial stages, higher than that during glacial stages, i.e. 1.9―5.0 g cm-2 ka-1, which is different from northern and southern SCS which show higher TMAR in glacial stages. By principle component analysis of grain size distribution of all the samples, two main control factors (F1 and F2) were obtained, which are responsible for about 80% variance of granularity. The contents of grain size population 1.26―2.66 μm% and 10.8―14.3 μm% which are sensible to F1 show high-frequency fluctuation, and correlate well with the summer insolation at 15oN. They exhibit a dis-tinct cyclicity with frequencies near 23 ka and 13 ka, in contrast to a strong frequency peak near 100 ka obtained in proxies 4.24―7.42 μm% and 30.1―43.7 μm% controlled mainly by F2. The sedimentary character of this part of the SCS was controlled by variations of input flux from two main source areas, namely the southwest and north SCS, which were transported by different circulations of surface current forced by East Asian summer monsoon and winter monsoon respectively. We believe that the East Asian summer monsoon has fluctuated with high frequency and been forced by changes in solar in-solation in low latitude associated with precession and half precession, while ice-volume forcing is probably a primary factor in determining the strength and timing of the East Asian winter monsoon but with less important insolation forcing.

关键词：南中国海陆源沉积物颗粒尺寸东亚季风

Chemical weathering in Malay Peninsula and North Borneo:Clay mineralogy and element geochemistry of river surface sediments

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Science China Earth Sciences 2011年第2期54卷 272-282页

作者： WANG Hao liU ZhiFei Edlic SATHIAMURTHY Christophe COliN li jianru ZHAO YuLong State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China Institute of Oceanography University Malaysia Terengganu Kuala Terengganu 21030 Malaysia Laboratoire IDES Bat. 504 UMR 8148 CNRS Universite de Paris XI Orsay 91405 France

Weathering products of silicate rocks are particularly useful for evaluating the continental chemical weathering on the Earth's surface and its *** mineralogy and major-element geochemistry of surface sediment samples collected in major rivers of Malay Peninsula and North Borneo in the tropical Southeast Asian region are used to study the present chemical weathering process and its controlling factors of tropical *** results indicate that the clay mineral assemblage in Malay Peninsula consists dominantly of kaolinite(average 80%) and minor illite(average 17%),almost without chlorite and smectite,whereas in North Borneo it consists mainly of illite and chlorite,with minor amounts of kaolinite(average 14%) and no *** contents of illite and chlorite in both Northwest and Northeast Borneo are 84% and 87%,***-element geochemical results of both bulk and clay-fraction sediments show intensive chemical weathering degree for both ***,the chemical weathering degree is gradually strengthened from Northeast Borneo,Northwest Borneo,to Malay Peninsula,and it is extremely intensive in Malay *** results indicate that,in the tropical Southeast Asian region exampled by Malay Peninsula and Borneo,climatic condition of tropical warm temperature and East Asian monsoon rainfall is the first-order controlling factor on the chemical weathering,resulting in intensive chemical weathering throughout tropical areas,and tectonic activity and lithology of parent rocks are subordinate factors,which still have an important impact on the weathering products,forming completely different clay mineral assemblages between Malay Peninsula and Borneo.

关键词： clay minerals major elements fluvial sediments chemical weathering Malay Peninsula Borneo

Quaternary biogenic opal records in the South China Sea: linkages to East Asian monsoon, global ice volume and orbital forcing

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Science China Earth Sciences 2007年第5期50卷 710-724页

作者： WANG RuJian JIAN ZhiMin XIAO WenShen TIAN Jun li jianru CHEN RongHua ZHENG YuLong CHEN JianFang State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China

Particulate fluxes investigated in the central South China Sea (SCS) during 1993―1996 indicate that opal flux can be used to show primary productivity change, which provides a foundation for tracing the evolutionary relationship between the surface productivity and East Asian monsoon in the SCS during the late Quaternary glacial and interglacial periods. Based on the studies of opal % and their mass accumulation rates (MAR) at the six sites recovered from the SCS during the “Resolution” ODP Leg 184 and “Sonne” 95 cruise of the Sino-Germany cooperation, opal % and their MARs increased evidently in the northern sites since 470―900 ka, and they enhanced and reduced, respectively, during the glacial and interglacial periods. Whereas they increased obviously in the southern sites since 420―450 ka, and they augmented and declined, respectively, during the interglacial and glacial periods. The vari- ability in opal % and their MARs in the late Quaternary glacial cyclicity indicate the “seesaw” pattern of surface productivity in the SCS. The winter monsoon intensified during the glacial periods, surface productivity increased and decreased, respectively, in the northern and southern SCS. The summer monsoon strengthened during the interglacial periods, surface productivity increased and decreased, respectively, in the southern and northern SCS. The cross spectral analyses between the opal % in the northern and southern SCS during the Quaternary and global ice volume (δ 18O) and orbital forcing (ETP) indicate that the East Asian winter and summer monsoons could be ascribed to the different drive mechanisms. On the orbital time scale, the global ice volume change could be a dominant factor for the winter monsoon intension and temporal variations. As compared with the winter monsoon, the correlative summer solar radiation with the obliquity and precession in the Northern Hemisphere could be a mostly controlling factor for the summer monsoon intension and temporal variations.

关键词： biogenic opal surface productivity East Asian monsoon global ice volume orbital forcing ODP Leg 184 Quaternary South China Sea

Coastal seafloor observatory at Xiaoqushan in the East China Sea

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Chinese Science Bulletin 2011年第26期56卷 2839-2845页

作者： XU HuiPing ZHANG YanWei XU ChangWei li jianru liU Ding QIN RuFu LUO ShenQian FAN DaiDu State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China

The seafloor observation system is becoming an important infrastructure for marine research because it is transforming oceanic research from temporal investigation to long term *** East China Sea coastal seafloor observatory,located between 30°31′44″N,122°15′12″E and 30°31′34″N,122°14′40″E,is constructed near the Xiaoqushan Island outside the Hangzhou Bay on the inner continental shelf of the East China *** observatory is connected by a submarine optical fiber composite power cable that is more than one kilometer long and consists of a special junction box that transmits power and communication signals to different *** special junction box has a variety of waterproof plugs and connects to three different instruments installed in a trawl *** submarine optical fiber composite power cable is landed on the platform by The East China Sea Branch,State Oceanic Administration and the power is continuously supplied by the solar panels and solar battery on the top of the *** real time data are directly sent through the cable to the platform and are transmitted by CDMA wireless to the receiver at the State Key Laboratory of Marine Geology of Tongji *** at the observatory have been taken since April 20,2009 after installation and the results have been *** characteristics of the near bottom boundary are constrained by a sediment suspension model using portion of the observed *** particular,discussion is provided on the sea surface height anomaly at Xiaoqushan Island influenced by the tsunami driven by the 2010 Earthquake in *** successful establishment of the coastal seafloor observatory is the first step toward future development of seafloor observation systems in *** not only accumulates experiences in technology and engineering,but also paves the way for performing important oceanic research using the long term continuous observation platform.

关键词：海底观测站中国东海天文台沿海国家海洋局太阳能电池板国家重点实验室电力电缆

DNA Methylation Variation Is Identified in Monozygotic Twins Discordant for Congenital Heart Diseases

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Congenital Heart Disease 2024年第2期19卷 247-256页

作者： Shuliang Xia Huikang Tao Shixin Su Xinxin Chen li Ma jianru li Bei Gao Xumei liu Lei Pi Jinqing Feng Fengxiang li Jia li Zhiwei Zhang Guangdong Provincial People’s Hospital Southern Medical UniversityGuangzhou510100China Department of Cardiovascular Surgery Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatric Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of South China Structural Heart DiseaseGuangzhou510100China Clinical Physiology Laboratory Institute of PediatricsGuangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Key Laboratory of Research in Structural Birth Defect DiseaseGuangzhou510623China Department of Echocardiogram Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatrics Washington University School of MedicineSt.LouisMO63130USA Clinical Biological Resource Bank of Guangzhou Women and Children’s Medical Center Guangzhou Medical UniversityGuangzhou510623China

Aims:Multiple genes and environmental factors are known to be involved in congenital heart disease(CHD),but epigenetic variation has received little ***(MZ)twins with CHD provide a unique model for exploring this *** order to investigate the potential role of Deoxyribonucleic Acid(DNA)methyla-tion in CHD pathogenesis,the present study examined DNA methylation variation in MZ twins discordant for CHD,especially ventricular septal defect(VSD).Methods and Results:Using genome-wide DNA methylation profiles,we identified 4004 differentially methylated regions(DMRs)in 18 MZ twin pairs discordant for CHD,and 2826 genes were *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis revealed a list of CHD-associated *** further investigate the role of DNA methylation in VSD,data from 7 pairs of MZ twins with VSD were *** identified 1614 DMRs corresponding to 1443 genes associated with arrhythmogenic right ventricular cardiomyopathy,cyclic guanosine monopho-sphate-protein kinase G(cGMP-PKG)signaling pathway by KEGG analysis,and cell-cell adhesion,calcium ion transmembrane transport by GO analysis.A proportion of DMR-associated genes were involved in calcium signaling *** methylation changes of calcium signaling genes might be related to VSD ***:CHD is associated with differential DNA methylation in MZ *** may be etiologically linked to DNA methylation,and methylation of calcium signaling genes may be involved in the development of VSD.

关键词： Congenital heart disease monozygotic twins methylation modification epigenetics

Src inhibition rescues FUNDC1-mediated neuronal mitophagy in ischaemic stroke

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Stroke & Vascular Neurology 2024年第4期9卷 367-379,I0022-I0031页

作者： Tianchi Tang li-bin Hu Chao Ding Zhihua Zhang Ning Wang Tingting Wang Hang Zhou Siqi Xia linfeng Fan Xiong-jie Fu Feng Yan Xiangnan Zhang Gao Chen jianru li Department of Neurosurgery Zhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 2NeurosurgeryZhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 3Zhejiang University School of MedicineHangzhouZhejiangChina 4Zhejiang University Department of PharmacologyHangzhouZhejiangChina

Background Ischaemic stroke triggers neuronal mitophagy,while the involvement of mitophagy receptors in ischaemia/reperfusion(I/R)injury-induced neuronal mitophagy remain not fully ***,we aimed to investigate the involvement of mitophagy receptor FUN14 domain-containing 1(FUNDC1)and its modulation in neuronal mitophagy induced by I/R *** Wild-type and FUNDC1 knockout mice were generated to establish models of neuronal I/R injury,including transient middle cerebral artery occlusion(tMCAO)in vivo and oxygen glucose deprivation/reperfusion in *** outcomes of mice with two genotypes were *** mitophagy was analysed both in vivo and in *** of FUNDC1 and its regulator Src were *** impact of Src on FUNDC1-mediated mitophagy was assessed through administration of Src antagonist *** To our surprise,FUNDC1 knockout mice subjected to tMCAO showed stroke outcomes comparable to those of their wild-type *** neuronal mitophagy could be activated by I/R injury,FUNDC1 deletion did not disrupt neuronal *** activation of FUNDC1,represented by dephosphorylation of Tyr18,was detected in the early stages(within 3hours)of neuronal I/R injury;however,phosphorylated Tyr18 reappeared and even surpassed baseline levels in later stages(after 6hours),accompanied by a decrease in FUNDC1-light chain 3 *** inactivation of FUNDC1 was associated with Src activation,represented by phosphorylation of Tyr416,which changed in parallel with the level of phosphorylated FUNDC1(Tyr18)during neuronal I/R ***,FUNDC1-mediated mitophagy in neurons under I/R conditions can be rescued by pharmacological inhibition of *** FUNDC1 is inactivated by Src during the later stage(after 6hours)of neuronal I/R injury,and rescue of FUNDC1-mediated mitophagy may serve as a potential therapeutic strategy for treating ischaemic stroke.

关键词： FUNDC1 involvement injury