检索结果-南通市图书馆

Journal of Energy Chemistry 2024年第9期96卷 79-88页

作者： Xiaoke Wang Titi li Xixi Zhang Yaxin Wang Hongfei li Hai-feng li Gang Zhao Cuiping Han Institute of Applied Physics and Materials Engineering University of MacaoAvenida da UniversidadeTaipaMacao 999078China School of Physics and Technology University of JinanJinan 250022ShandongChina Songshan Lake Materials Laboratory Dongguan 523808GuangdongChina Faculty of Materials Science and Energy Engineering Shenzhen University of Advanced TechnologyShenzhen 518055GuangdongChina Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055GuangdongChina

Magnesium ion batteries(MIBs)are a potential field for the energy storage of the future but are restricted by insufficient rate capability and rapid capacity ***-sodium hybrid ion batteries(MSHBs)are an effective way to address these ***,we report a new type of MSHBs that use layered sodium vanadate((Na,Mn)V_(8)O_(20)·5H_(2)O,Mn-NVO)cathodes coupled with an organic 3,4,9,10-perylenetetracarboxylic diimide(PTCDI)anode in Mg^(2+)/Na^(+)hybrid *** electrochemical cycling,Mg^(2+)and Na^(+)co-participate in the cathode reactions,and the introduction of Na^(+)promotes the structural stability of the Mn-NVO cathode,as cleared by several ex-situ ***,the Mn-NVO cathode presents great specific capacity(249.9 mA h g^(−1)at 300 mA g^(−1))and cycling(1500 cycles at 1500 mA g^(−1))in the Mg^(2+)/Na^(+)hybrid ***,full battery displays long lifespan with 10,000 cycles at 1000 mA g^(−1).The rate performance and cycling stability of MSHBs have been improved by an economical and scalable method,and the mechanism for these improvements is discussed.

关键词： Aqueous battery Hybrid ion battery Mg^(2+)/Na^(+)co-intercalation High-rate performance Organic-water hybrid electrolyte

Triclosan-conjugated,lipase-responsive Polymeric Micelles for Eradication of Staphylococcal Biofilms

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第6期42卷 718-728页

作者： Yan-Qiang Huang Yuan-feng li Yong liu lin-Qi Shi Guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance Youjiang Medical University for NationalitiesBaise533000China Translational Medicine Laboratory the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325035China Wenzhou Institute University of Chinese Academy of SciencesWenzhou325001China State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of Educationand Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin300071China

Bacterial biofilms present a significant challenge in treating drug-resistant infections,necessitating the development of innovative *** this study,we introduce triclosan-conjugated,lipase-responsive polymeric micelles designed to exploit biofilm properties and serve as a responsive drug delivery *** micelles were created using an amphiphilic block polymer synthesized via ring-opening polymerization ofε-caprolactone(CL)and triclosan-containing cyclic trimethylene carbonate(MTC-Tri).Poly(ethylene glycol)(PEG-OH)acted as the macro-initiator,resulting in micelles with a PEG shell that facilitated their penetration into bacterial *** important advantage of our micelles lies in their interaction with local bacterial lipases within *** lipases triggered rapid micelle degradation,releasing triclosan in a controlled *** liberated triclosan effectively eliminated bacteria embedded in the ***,the triclosan-conjugated micelles displayed minimal toxicity to murine fibroblasts,indicating their biocompatibility and *** finding emphasizes the potential application of these micelles in combatting drug resistance observed in bacterial *** triclosan-conjugated,lipase-responsive polymeric micelles exhibit promising characteristics for addressing drug resistance in bacterial *** harnessing biofilm properties and implementing a responsive drug delivery system,we seek to provide an effective solution in the fight against drug-resistant bacteria.

关键词： Self-assembly Polymer prodrug Ring-opening polymerization Biofilm eradication Cytotoxicity

The Q-index and Connectivity of Graphs

在线全文

学校读者我要写书评

暂无评论

Journal of the Operations Research Society of China 2024年第2期12卷 505-519页

作者： Peng-li Zhang li-Hua feng Wei-Jun liu Xiao-Dong Zhang School of Mathematical Sciences MOE-LSCSHL-MACShanghai Jiao Tong UniversityShanghai 200240China School of Mathematics and Statistics Central South UniversityChangsha 410083HunanChina

A connected graph G is said to be k-connected if it has more than k vertices and remains connected whenever fewer than k vertices are *** this paper,for a connected graph G with sufficiently large order,we present a tight sufficient condition for G with fixed minimum degree to be k-connected based on the *** result can be viewed as a spectral counterpart of the corresponding Dirac-type condition.

关键词： Q-index Minimum degree k-connected

PEGylated graphene oxide-mediated stimulation of vascular endothelial cells and responsive release of PD-1/PD-L1 inhibitor for efficient chemo-immunotherapy against cancer Author links open overlay panel

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第8期91卷 280-290页

作者： Yan Wang feng li Shuang Wang Jiaqi Meng Xiao Zhang Wei Wei State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Immune checkpoint blockade(ICB)has emerged as a promising immunotherapeutic modality against cancer in the ***,only 10-30%of patients respond to ICB,primarily due to poor immunogenicity and insufficient T cell infiltration in solid ***,we presented an approach for high-performance cancer treatment using the programmed cell death protein-1 and programmed cell death ligand-1(PD-1/PD-L1)inhibitor(BMS-202)-loaded PEGylated graphene oxide(GPi).On the one hand,GPi dissociated tight junctions of vascular endothelial cells(VECs)in tumor,thus promoting the extravasation and intratumoral accumulation of liposomal doxorubicin(lipDox),which then effectively induced immunogenic cell death of tumor *** the other hand,GPi also stimulated VECs to upregulate the expression of cell-cell interaction molecules,such as intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1,which facilitated the infiltration of T cells in *** acting as a stimulator of VECs,GPi could exert responsive release of BMS-202 under the acidic tumor microenvironment and blockade PD-1/PD-L1 axis in ***,the alternating administration of GPi and lipDox effectively inhibited tumor growth in a 4T1 tumor model,providing a novel treatment mode for chemo-immunotherapy.

关键词： PEGylated graphene oxide Vascular endothelial cells Immune checkpoint blockade Immunogenic cell death Chemo-immunotherapy

Transient elastography with controlled attenuation parameter for the diagnosis of colorectal polyps in patients with nonalcoholic fatty liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第12期12卷 2050-2055页

作者： Lan Wang Yan-Fei li li-feng Dong Department of Gastroenterology Beijing Chuiyangliu HospitalBeijing 100022China

BACKGROUND The severity of nonalcoholic fatty liver disease(NAFLD)and lipid metabolism are related to the occurrence of colorectal ***-controlled attenuation parameters(liver-CAPs)have been established to predict the prognosis of hepatic steatosis *** To explore the risk factors associated with colorectal polyps in patients with NAFLD by analyzing liver-CAPs and establishing a diagnostic *** Patients who were diagnosed with colorectal polyps in the Department of Gastroenterology of our hospital between June 2021 and April 2022 composed the case group,and those with no important abnormalities composed the control *** area under the receiver operating characteristic curve was used to predict the diagnostic *** were considered statistically significant when Pliver-CAP in the case group were significantly greater than those in the control group(mmol/L,1.74 vs 1.05;dB/m,282 vs 254,Pliver-CAP were found to be independent risk factors for colorectal polyps,with ORs of 2.338(95%CI:1.154–4.733)and 1.019(95%CI:1.006–1.033),respectively(Pliver-CAP and TG combined with liver-CAP(TG+CAP)(P>0.05).When the liver-CAP was greater than 291 dB/m,colorectal polyps were more likely to *** The levels of TG and liver-CAP in patients with colorectal polyps are significantly greater than those patients without ***-CAP alone can be used to diagnose NAFLD with colorectal polyps.

关键词： Colorectal polyps Nonalcoholic fatty liver disease liver-controlled attenuation parameter liver fibroscan Diagnostic model

Enhancing the mechanical properties of casting eutectic high -entropy alloys via W addition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1364-1372页

作者： Xu Yang Dezhi Chen li feng Gang Qin Shiping Wu Ruirun Chen National Key Laboratory for Precision Hot Processing of Metals School of Material Science and EngineeringHarbin Institute of TechnologyHarbin 150001China

The effect of W element on the microstructure evolution and mechanical properties of Al_(1.25)CoCrFeNi3 eutectic high-entropy alloy and Al_(1.25)CoCrFeNi_(3-x)W_(x)(x=0,0.05,0.1,0.3,and 0.5;atomic ratio)high-entropy alloys(HEAs)were *** show that the Al_(1.25)CoCrFeNi_(3-x)W_(x) HEAs are composed of face-centered cubic and body-centered cubic(BCC)*** W content increases,the microstructure changes from eutectic to *** addition of W lowers the nucleation barrier of the BCC phase,decreases the valence electron concentration of the HEAs,and replaces Al in the BCC phase,thus facilitating the nucleation of the BCC *** results show that the addition of W greatly improves the mechanical properties,and solid-solution,heterogeneous-interface,and second-phase strengthening are the main strengthening *** yield strength,tensile strength,and elongation of the Al_(1.25)CoCrFeNi2.95W0.05 HEA are 601.44 MPa,1132.26 MPa,and 15.94%,respectively,realizing a balance between strength and *** fracture mode of the Al_(1.25)CoCrFeNi_(3-x)W_(x) HEAs is ductile–brittle mixed fracture,and the crack propagates and initiates in the BCC *** eutectic lamellar structure impedes crack propagation and maintains plasticity.

关键词： high-entropy alloy microstructure mechanical property fracture behavior

Optimal dispatching strategy for residential demand response considering load participation

在线全文

学校读者我要写书评

暂无评论

Global Energy Interconnection 2024年第1期7卷 38-47页

作者： Xiaoyu Zhou Xiaofeng liu Huai liu Zhenya Ji feng li School of Electrical and Automation Engineering Nanjing Normal UniversityNanjing 210023P.R.China

To facilitate the coordinated and large-scale participation of residential flexible loads in demand response(DR),a load aggregator(LA)can integrate these loads for *** this study,a residential DR optimization scheduling strategy was formulated considering the participation of flexible loads in ***,based on the operational characteristics of flexible loads such as electric vehicles,air conditioners,and dishwashers,their DR participation,the base to calculate the compensation price to users,was determined by considering these loads as virtual energy *** was quantified based on the state of virtual energy storage during each time ***,flexible loads were clustered using the K-means algorithm,considering the typical operational and behavioral characteristics as the cluster ***,the LA scheduling strategy was implemented by introducing a DR mechanism based on the directrix *** simulation results demonstrate that the proposed DR approach can effectively reduce peak loads and fill valleys,thereby improving the load management performance.

关键词： Residential demand response Flexible loads Load participation Load aggregator

Microneedle patch loaded with ferritin-nanocaged doxorubicin for locally targeted drug delivery and efficient skin cancer treatment

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第5期88卷 282-289页

作者： feng li Yuan Yang Hua Yue Shuang Wang Xiao Zhang Wei Wei State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Ferritin has emerged as a promising nanocarrier for delivering therapeutic agents to ***,the limited drug loading and the off-target impacts after systemic administration remain challenges for cancer treatment with ferritin-based ***,we develop a microneedle patch loaded with ferritin-nanocaged doxorubicin(DoxFe@Fn/MN)for skin cancer ***,doxorubicin(Dox)is encapsulated in ferritin(Fn)using an iron core-assisted strategy,which results in a 3.4-fold increase in Dox loading compared to the direct loading ***,a polyvinyl alcohol-based microneedle(MN)patch is used for the transdermal delivery of DoxFe@Fn,enabling targeted tumour accumulation of DoxFe@Fn and preventing off-target *** released DoxFe@Fn can bind to CD71 highly expressed on skin cancer cells,facilitating its *** a result,the DoxFe@Fn/MN therapy presents a robust antitumour effect in a melanoma tumour model,showing its potential as a promising therapeutic modality for skin cancer treatment.

关键词： Ferritin Microneedle Skin cancer Drug delivery

Three-channel CMOS transimpedance amplifier for liDAR sensor receiver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2024年第1期35卷 74-80页

作者： liU Ruqing ZHU Jingguo JIANG Yan li feng JIANG Chenghao MENG Zhe Photoelectric R&D Center Academy of Opto-ElectronicsChinese Academy of SciencesBeijing 100094China

For time-of-flight(TOF)light detection and ranging(liDAR),a three-channel high-performance transimpedance amplifier(TIA)with high immunity to input load capacitance is presented.A regulated cascade(RGC)as the input stage is at the core of the complementary metal oxide semiconductor(CMOS)circuit chip,giving it more immunity to input photodiode detectors.A simple smart output interface acting as a feedback structure,which is rarely found in other designs,reduces the chip size and power consumption *** circuit is designed using a 0.5μm CMOS process technology to achieve low *** device delivers a 33.87 dB?transimpedance gain at 350 *** a higher input load capacitance,it shows a-3 dB bandwidth of 461 MHz,indicating a better detector tolerance at the front end of the *** a 3.3 V supply voltage,the device consumes 5.2 mW,and the total chip area with three channels is 402.8×597.0μm2(including the test pads).

关键词： transimpedance amplifier(TIA) three-channel regulated cascade(RGC) light detection and ranging(liDAR)

Dynamic simulation analysis of molten salt reactor-coupled air-steam combined cycle power generation system

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第2期35卷 222-233页

作者： Jing-Lei Huang Guo-Bin Jia li-feng Han Wen-Qian liu li Huang Zheng-Han Yang Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

A nonlinear dynamic simulation model based on coordinated control of speed and flow rate for the molten salt reactor and combined cycle systems is proposed here to ensure the coordination and stability between the molten salt reactor and power *** model considers the impact of thermal properties of fluid variation on accuracy and has been validated with *** study reveals the capability of the control system to compensate for anomalous situations and maintain shaft stability in the event of perturbations occurring in high-temperature molten salt tank outlet ***,the control system’s impact on the system’s dynamic characteristics under molten salt disturbance is also *** results reveal that after the disturbance occurs,the controlled system benefits from the action of the control,and the overshoot and disturbance amplitude are positively correlated,while the system power and frequency eventually return to the initial *** simulation model provides a basis for utilizing molten salt reactors for power generation and maintaining grid stability.

关键词： Molten salt reactor Combined cycle Dynamic characteristic Control