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Biomedical and Environmental Sciences 2012年第3期25卷 352-358页

作者： li zong ji WANG Ya Na WANG Qi ZHAO Wei Center of Scientific Technology of Ningxia Medical University Yinchuan 750004 Ningxia Hui Autonomous Region China Department of Medical Genetics & Cell Biology Ningxia Medical University Yinchuan 750004 Ningxia Hui Autonomous Region China The Affiliated Hospital of Ningxia Medical University Yinchuan 750004 Ningxia Hui Autonomous Region China

Objective To investigate the protective immunity against Echinococcus granulosus in mice immunized with rEg14-3-3. Methods ICR mice were subcutaneously immunized three times with rEg14-3-3, followed by the challenge with Echinococcus granulosus protoscoleces intraperitoneally and then sacrificed after six months of post-challenge to detect the proliferation of splenocytes by MTT assay, and to measure the secretion of IL-2, IL-4, IL-20, and IFN -y by EliSA. The rate of reduced hydatid cyst and the levels of IgE, igG and IgG subclasses in sera were examined. Results Mice vaccinated with rEg14-3-3 and challenged with protoscoleces revealed significant protective immunity of 84.47%. EliSA analysis indicated that the immunized mice generated specific high levels of IgG and the prevailing isotypes of IgG were IgG1 and IgG2a. Splenocytes from mice immunized with rEg14-3-3 showed a significant proliferation response. The secretion of IFN-V and IL-2 increased significantly in the vaccinated mice whereas there was no significant difference in IL-4 and IL-20 levels between vaccinated and control mice. Conclusion The results indicate that the rEg24-3-3 vaccine could induce a high level of protective immunity as a promising vaccine candidate to prevent cystic echinococcosis.

关键词： Eg14-3-3 Echinococcus granulosus Vaccine Immunoprotection

A Bio-inspired Mutual-hook Strategy for the Soft Finger to Improve Load-bearing Capacity and Grasping Stability

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Journal of Bionic Engineering 2024年第3期21卷 1290-1304页

作者： jie Huang lingjie Gai Xiaofeng zong Yunquan li School of Automation China University of GeosciencesWuhan430074China Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex System Wuhan430074China The Shien-Ming Wu School of Intelligent Engineering South China University of TechnologyGuangzhou510641China

Soft grippers have great potential applications in daily life,since they can compliantly grasp soft and delicate ***,the highly elastic fingers of most soft grippers are prone to separate from each other while grasping objects due to their low stiffness,thus reducing the grasping stability and load-bearing *** tackle this problem,inspired from the venus flytrap plant,this work proposes a mutual-hook mechanism to restrain the separation and improve the grasping performance of soft *** novel soft gripper design consists of three modules,a soft finger-cot,two Soft Hook Actuators(SHAs)and two sliding ***,the soft finger-cot covers on the soft finger,increasing the contact area with the target object,two SHAs are fixed to the left and right sides of the finger-cot,and the sliding mechanisms are designed to make SHAs stretch *** demonstrate that the proposed design can restrain the separation of soft fingers substantially,and the soft fingers with the finger-cots can grasp objects three times heavier than the soft fingers without the proposed *** proposed design can provide invaluable insights for soft fingers to restrain the separation while grasping,thus improving the grasping stability and the load-bearing capacity.

关键词： Soft robotics Soft bionic finger-cot Soft hook actuator Grasping stability Load-bearing capacity

Data-driven active vibration control for helicopter with trailing-edge flaps using adaptive dynamic programming

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Chinese Journal of Aeronautics 2024年第6期37卷 151-166页

作者： Yu CHEN Qun zong Xiuyun ZHANG jinna li School of Electrical and Information Engineering Tianjin UniversityTianjin 300072China School of Information and Control Engineering Liaoning Petrochemical UniversityFushun 113001China

The helicopter Trailing-Edge Flaps(TEFs)technology is one of the recent hot topics in morphing wing *** employing controlled deflection,TEFs can effectively reduce the vibration level of ***,designing specific vibration reduction control methods for the helicopters equipped with trailing-edge flaps is of significant practical *** paper studies the optimal control problem for helicopter-vibration systems with TEFs under the framework of adaptive dynamic programming combined with Reinforcement Learning(RL).Time-delay and disturbances,caused by complexity of helicopter dynamics,inevitably deteriorate the control performance of vibration *** solve this problem,a zero-sum game formulation with a linear quadratic form for reducing vibration of helicopter systems is presented with a virtual *** this context,an off-policy reinforcement learning algorithm is developed to determine the optimal control *** algorithm utilizes only vertical vibration load data to achieve a policy that reduces vibration,attains Nash equilibrium,and addresses disturbances while compensating for time-delay without knowledge of the dynamics of the helicopter *** effectiveness of the proposed method is demonstrated in a virtual platform.

关键词： Active control Adaptive dynamic program-ming Helicopter rotor Vibration control Zero-sum game

Probabilistic seismic inversion based on physics-guided deep mixture density network

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Petroleum Science 2024年第3期21卷 1611-1631页

作者： Qian-Hao Sun Zhao-Yun zong Xin li National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao266580ShandongChina Laoshan Laboratory Qingdao266580ShandongChina CNOOC Research Institute Ltd. Beijing100028China

Deterministic inversion based on deep learning has been widely utilized in model parameters *** by logging data,seismic data,wavelet and modeling operator,deterministic inversion based on deep learning can establish nonlinear relationships between seismic data and model ***,seismic data lacks low-frequency and contains noise,which increases the non-uniqueness of the *** conventional inversion method based on deep learning can only establish the deterministic relationship between seismic data and parameters,and cannot quantify the uncertainty of *** order to quickly quantify the uncertainty,a physics-guided deep mixture density network(PG-DMDN)is established by combining the mixture density network(MDN)with the deep neural network(DNN).Compared with Bayesian neural network(BNN)and network dropout,PG-DMDN has lower computing cost and shorter training time.A low-frequency model is introduced in the training process of the network to help the network learn the nonlinear relationship between narrowband seismic data and low-frequency *** addition,the block constraints are added to the PG-DMDN framework to improve the horizontal continuity of the inversion *** illustrate the benefits of proposed method,the PG-DMDN is compared with existing semi-supervised inversion *** synthetic data examples of Marmousi II model are utilized to quantify the influence of forward modeling part,low-frequency model,noise and the pseudo-wells number on inversion results,and prove the feasibility and stability of the proposed *** addition,the robustness and generality of the proposed method are verified by the field seismic data.

关键词： Deep learning Probabilistic inversion Physics-guided Deep mixture density network

Growth and development of children in China:achievements,problems and prospects

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World Journal of Pediatrics 2024年第2期20卷 97-104页

作者： Xin-Nan zong Hui li Department of Growth and Development Capital Institute of PediatricsBeijing 100020China

Growth reflects the general condition of society,and is a measure of the nutritional and hygienic status of a population[1,2].Nutrition is one of the most important components of children’s well-being[3].The Chinese government attaches great importance to children’s health and development,with a clear statement and consistent practice for“Children are the future and hope of the motherland”.

关键词： mother statement children

Height and body mass index trajectories from 1975 to 2015 and prevalence of stunting,underweight and obesity in 2016 among children in Chinese cities:findings from five rounds of a national survey

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World Journal of Pediatrics 2024年第4期20卷 404-412页

作者： Xin‑Nan zong Hui li Ya‑Qin Zhang Department of Growth and Development Capital Institute of PediatricsBeijing 100020China

Background A more comprehensive assessment of growth and nutrition in children is required in China due to rapid socioeconomic *** aimed to investigate height and body mass index(BMI)trajectories from 1975 to 2015 and the prevalence of stunting and obesity in 2016 among children in Chinese *** A total of 904,263 children from birth to 6.9 years were collected from a series of nationally representative surveys in *** and BMI trajectories and prevalence of stunting,underweight,overweight and obesity were *** The average height level of Chinese urban children under 7 years presented a positive secular trend from 1975 to 2015;however,a slowing tendency occurred in 2005‒*** apparent increase was observed at the 5th,50th and 95th percentiles of BMI in urban children aged 3 years and older,with a more prominent increase at the 95th *** total prevalence of stunting and underweight under 7 years was 1.4%and 2.0%,*** total prevalence of overweight and obesity under 7 years was 12.6%and 4.3%,respectively,with 12.7%and 4.9%for boys,12.6%and 3.6%for girls,12.1%and 4.0%in urban areas and 13.1%and 4.5%in suburban rural *** The average height level of Chinese urban children has reached World Health Organization child growth standards since 2005 and presented a slowing tendency in secular trend in 2005‒*** attention and efforts and public health interventions should be urgently made to combat overweight and obesity among preschool children.

关键词： Body mass index Children Height Obesity Stunting

Domain wall network:A dual solution for gravitational waves and Hubble tension?

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Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 39-46页

作者： ligong Bian Shuailiang Ge Changhong li jing Shu Junchao zong Department of Physics and Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 401331China Center for High Energy Physics Peking UniversityBeijing 100871China School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Department of Astronomy Key Laboratory of Astroparticle Physics of Yunnan ProvinceSchool of Physics and AstronomyYunnan UniversityKunming 650091China Beijing Laser Acceleration Innovation Center Beijing 101400China Department of Physics Nanjing UniversityNanjing 210093China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China

We explore the possibility that domain wall networks generate the stochastic gravitational wave background(SGWB) observed as a strong common power-law process in the Data Release-2 of Parkes Pulsar Timing Array. We find that a broad range of parameters, specifically wall tension around σ_(DW)^(29-414 TeV)^(3) and wall-decay temperature within T_(d) ~ 20-257 MeV, can explain this phenomenon at a 68% credible level. Meanwhile, the same parameters could ease the Hubble tension if particles from these domain wall networks decay into dark radiation. We establish a direct analytical relationship, ΩGW(f_(p), T_(0))h^(2)~ Ω_(rad)h^(2)(Ω_νΩN_(eff))^(2),to illustrate this coincidence, underlining its importance in the underlying physics and potential applicability to a wider range of models and data. Conversely, if the common power-law process is not attributed to domain wall networks, our findings impose tight limits on the wall tension and decay temperature.

关键词： domain wall gravitational waves Hubble tension

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Anisotropic Mechanical Response of Nacre to Heat Treatment Under Indentation:Effect of Structural Orientation

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Journal of Bionic Engineering 2024年第3期21卷 1453-1464页

作者： Simin liang Yingying li Hongmei ji Xiaowu li Department of Materials Physics and Chemistry School of Materials Science and EngineeringKey Laboratory for Anisotropy and Texture of MaterialsMinistry of EducationNortheastern UniversityShenyang110819China

It is generally considered that heat treatments have a negative impact on the mechanical properties of nacre due to thermal decomposition of the organic ***,the present work investigated the microindentation behavior on fresh and heat-treated nacres from two orthogonal directions,and the results demonstrate that both hardness value and damage tolerance can remain almost unchanged on the cross-section with the organic matrix degeneration,despite a significant deterioration on the platelet *** analyses suggest that the anisotropic response of indentation behavior to heat treatment in nacre is primarily caused by its structural ***,compared with a single layer of irregular interplatelet interfaces in cross-sectional specimens,the multiple layers of parallel interlamellar interfaces in in-plane specimens exhibit a much greater ability to impede indenter-triggered destruction,and heat treatments would reduce the in-plane hardness but nearly have no effect on the cross-sectional ***,the deeper embedding of platelets in cross-sectional specimens enhances their resistance to interface cracking caused by organic matrix degradation at high temperatures,leading to a reduced sensitivity to ***,the indentation behavior of nacre shows different tendencies in response to variations in the organic matrix state along normal and parallel directions.

关键词： Nacre Structural orientation Heat treatment Indentation behavior Organic matrix

CO_(2) corrosion of X80 steel welded joints under micro-turbulence induced by welding reinforcement height

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Journal of Iron and Steel Research International 2024年第4期31卷 1015-1032页

作者： Xiao-hui Dou Bin li zong-hao He Xin-wei Zhang Da-lei Zhang Yan li School of Materials Science and Engineering China University of Petroleum(East China)Qingdao 266580ShandongChina School of Energy and Power Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina

Corrosion failure accidents owing to flow erosion and pipeline corrosion frequently occur during *** welding reinforcement height(WRH)can induce locally micro-turbulent flow field,which aggravates local corrosion of welded joints.A high wall shear stress(WsS)experimental setup was established to conduct the online electrochemical corrosion *** influence of WRH sizes on local corrosion of welded joints was studied at different flow *** electrochemical signals of the local corrosion of X80 welded joints at different flow rates were monitored in real time using electrochemical impedance spectroscopy and wire beam *** addition,the corrosion products composition and properties were *** results show that the micro-turbulent flow fields induced by the WRHs can enhance ion mass transfer near the welded *** corrosion products on the WRH surface also present different microscopic morphologies at different flow *** strong flow fields,the locally enhanced wsS can peel off the dense corrosion product partially,leading to the electrochemical distribution of large cathode and small anode,which accelerates the occurrence and development processes of the local corrosion of welded *** scientific guidelines for the corrosion protection of long-distance oil and gas pipelines can be potentially provided.

关键词： X80 steel welded joint Welding reinforcement height Micro-turbulence CO_(2)corrosion-Ion mass transfer

基于变结构的水下航行体航行姿态控制系统设计方法

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兵工学报 2013年第3期34卷 301-309页

作者：张西勇王树宗李宗吉海军工程大学兵器工程系湖北武汉430033

水下航行体在高速转弯时,由于俯仰、偏航和横滚3个通道间存在较大的耦合,以及水下海流的不确定性干扰等因素的影响,水下航行体的姿态控制难度较大,传统控制技术无法达到控制目的。为了解决水下航行体姿态解耦控制的难题,通过水下航行体... 详细信息

水下航行体在高速转弯时,由于俯仰、偏航和横滚3个通道间存在较大的耦合,以及水下海流的不确定性干扰等因素的影响,水下航行体的姿态控制难度较大,传统控制技术无法达到控制目的。为了解决水下航行体姿态解耦控制的难题,通过水下航行体旋转动力学方程构建了水下航行体姿态运动子系统状态方程,并应用变结构控制策略设计了水下航行体姿态控制器,理论推导和仿真表明:所设计的控制器能够使得水下航行体姿态角稳定地跟踪指令航向角,并对海流干扰具有强鲁棒性,实现了水下航行体姿态子系统间的解耦控制。

关键词：自动控制技术水下航行体变结构控制解耦