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Two-parameter-dependent Drag Coefficient Over Sea Surface by Turbulent Modeling

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Communications in Nonlinear Science and Numerical Simulation 1999年第1期4卷 8-12页

作者： Jiachun li and zifan ZHANG (Institute of mechanics, CAS, Beijing 100080, China) Institute of mechanics CAS Beijing 100080 China

A new model accounting for both turbulence and sea state effects has been proposed in the current paper to describe momentum exchange through air-sea interface. While long wave components mainly change air flow profile, short wave components exert their influences on the momentum exchange via turbulent stress, which leads to the growth of drag coefficients by a factor of two in young wave age circumstances. As a typical case study, we have considered neutral ABL over a representative regular wave with roughness due to short capillary waves riding over it. The results by the present model are in reasonable agreement with Maat’s analysis numerically fitted by HEXMAX data and Janssen’s results. Two parameter dependence of drag coefficient can resolve the existing discrepency between theory and observations.

关键词： air-sea interaction drag coefficient waveage

Synergistic effect of homojunction and Ohmic junctions in CdS boosting spatial charge separation for U(VI)photoreduction

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Nano Research 2024年第8期17卷 6849-6859页

作者： Haonan Pei Zhimin Dong zifan li Jian Huang Yuanping Jiang Zuojia li lin Xu Xiaohong Cao Yunhai liu Zhibin Zhang Guoping Yang State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China

Photo-excited holes usually migrate to the surface of the catalyst and rapidly recombine with electrons,reducing the photocatalytic reduction efficiency of uranium(VI)(U(VI))in radioactive ***,we employed a straightforward synthesis technique to meticulously shape and manipulate the morphology of CdS to precisely construct CdS-Ni dandelion-like composites with different aspect ***,the introduction of crystal facet homojunction with Ohmic contacts in this unique morphology siqnificantly improves the photocatalytic ***-dependent photoluminescence spectroscopy(TD-PL)verifies that the composite material positively effects on the dissociation of *** 30 min,CdS(002)/(102)/Ni-4 removed 98% of the uranium content in solution and showed a rather high apparent rate constant(0.114 min^(−1)),which was 4.8 times higher than that of CdS nanospheres(NSs)(0.024 min^(−1))and 3.7 times higher than that of CdS nanorods(NRs)(0.031 min^(−1)).This is much higher the most reported photocatalysts for U(VI)*** after 5 consecutive cycles,the photocatalytic efficiency only decreased by 7%.This offers a fresh perspective on constructing a new perspective for building a green,efficient,and multi mechanism collaborative catalytic system to remediate environmental pollution.

关键词： uranium dandelion-shaped axial size effect crystal facet homojunction ohmic contact

Synergy of photocatalytic reduction and adsorption for boosting uranium removal with PMo_(12)/UiO-66 heterojunction

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Chinese Chemical Letters 2022年第7期33卷 3577-3580页

作者： Zhibin Zhang zifan li Zhimin Dong Fengtao Yu Yingcai Wang Youqun Wang Xiaohong Cao Yuhui liu Yunhai liu Jiangxi Province Key Laboratory of Synthetic Chemistry East China University of TechnologyNanchang 330013China State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China

In this work,we proposed a new U(Ⅵ)removal strategy combining adsorption and photocatalytic reduction by the PMo_(12)/UiO-66 *** PMo_(12)has been encapsulated in the cavities of Ui O-66 by a one-step hydrothermal method,and the PMo_(12)/UiO-66 exhibited high adsorption capacity and photocatalytic *** maximal theoretical sorption capacity of U(Ⅵ)on 15%PMo_(12)/UiO-66 reached225.36 mg/g and the photoreduction rate of 15%PMo_(12)/UiO-66 is about thirty times as much as *** the light irradiation,the photogenerated electrons rapidly transport from UiO-66 to PMo_(12),and the photo-generated electrons could efficiently reduce the pre-enriched U(Ⅵ)to U(IV).This work provides new insights into remediation of the radioactive environment.

关键词： UiO-66 PMo12 Uranium Adsorption Photocatalytic reduction

Interspecies embryo transfer between rhesus and cynomolgus monkeys

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Journal of Genetics and Genomics 2020年第6期47卷 333-336页

作者： Ting Zhang Yu Kang li li Yin Zhou Xinglong Chen Yan Zhuo zifan li Hong Wang Yuyu Niu Weizhi Ji Shangang li Yongchang Chen Yunnan Key Laboratory of Primate Biomedicine Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming650500China Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming650500China Department of Pediatrics The First People's Hospital of Yunnan Province and The Affiliated Hospital of Kunming University of Science and TechnologyKunming650032China

Nonhuman primates(NHPs)present significant advantages over rodents for physiological and pharmacological investigations because of their higher genetic and physiological similarity to humans.

关键词： primates transfer similarity

A memristive-photoconductive transduction methodology for accurately nondestructive memory readout

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light(Science & Applications) 2024年第9期13卷 1801-1808页

作者： Zhe Zhou Yueyue Wu Keyuan Pan Duoyi Zhu zifan li Shiqi Yan Qian Xin Qiye Wang Xinkai Qian Fei Xiu Wei Huang Juqing liu Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)30 South Puzhu RoadNanjing 211816China Shandong Technology Center of Nanodevices and Integration School of MicroelectronicsShandong UniversityJinan 250100China Shaanxi Institute of Flexible Electronics(SIFE) Northwestern Polytechnical University(NPU)127 West Youyi RoadXi’an 710072China

Crossbar resistive memory architectures enable high-capacity storage and neuromorphic computing,accurate retrieval of the stored information is a prerequisite during read ***,conventional electrical readout normally suffer from complicated process,inaccurate and destructive reading due to crosstalk effect from sneak path *** we report a memristive-photoconductive transduction(MPT)methodology for precise and nondestructive readout in a memristive crossbar *** individual devices present dynamic filament form/fuse for resistance modulation under electric stimulation,which leads to photogenerated carrier transport for tunable photoconductive response under subsequently light pulse *** coherent signal transduction can be used to directly detect the memorized on/off states stored in each cell,and a prototype 4*4 crossbar memories has been constructed and validated for the fidelity of crosstalk-free readout in recall process.

关键词： crosstalk precise enable

Harvesting the Vibration Energy of CdS for High-Efficient Piezo-Photocatalysis Removal of U(Ⅵ):Roles of Shape Dependent and Piezoelectric Polarization

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Energy & Environmental Materials 2024年第5期7卷 387-399页

作者： Zhimin Dong Donglin Gao zifan li Haonan Pei lin Xu Jian Huang Xiaohong Cao Youqun Wang Ting Wang Qianglin Wei Zhibin Zhang Yunhai liu State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China Institute of Geology Chinese Academy of Geological Sciences26 Baiwanzhuang RoadBeijing 100037China

Piezo-photocatalysis could coalesce the advantages of mechanical vibration and solar energy perfectly to achieve high-efficiency catalytic ***,the quintessential piezoelectric material CdS nanowires with different aspect ratios are precisely constructed and applied for piezo-photocatalytic reduction of U(Ⅵ)for the first *** ultrasonic(60 kHz,100 W)induces piezoelectric potential to generate a 0.57 eV A^(-1)electric field,which is added to the direction of CdS(010)as a driving force to efficiently separate photogenerated *** alliance between piezoelectric effect and photocatalytic activity endows CdS NW-3 with the fastest piezo-photocatalytic rate under ultrasonic vibration and 5 W LED irradiation,and the relevant rate constant(0.042 min^(-1))is about 12 and 53.8 times than that of LED and *** importantly,93.74%of U(Ⅵ)could be removed from natural uranium mine ***,this piezo-photocatalysis system that reduces U(Ⅵ)to easily separable(UO_(2))O_(2)·2H_(2)O(s)provides valuable input for disposal applications of radioactive wastewater and broadens the horizons of nuclear energy utilization toward the advancement of carbon neutrality.

关键词： (UO_(2))O_(2)·2H_(2)O CdS nanowires piezo-photocatalytic piezo-potential U(Ⅵ)

Current state of stem cell research in non-human primates:an overview

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Medical Review

Medical Review 2023年第4期3卷 277-304页

作者： Junmo Wu Yuxi Shi Shanshan Yang Zengli Tang zifan li Zhuoyao li Jiawei Zuo Weizhi Ji Yuyu Niu Kunming University of Science and Technology KunmingYunnan ProvinceChina Yunnan Key Laboratory of Primate Biomedical Research KunmingYunnan ProvinceChina

The remarkable similarity between non-human primates(NHPs)and humans establishes them as essential models for understanding human biology and diseases,as well as for developing novel therapeutic strategies,thereby providing more comprehensive reference data for clinical *** stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprecedented opportunities for cell therapies against intractable diseases and *** continue to harness the potential of these biotechnological therapies,NHPs are increasingly being employed in preclinical trials,serving as a pivotal tool to evaluate the safety and efficacy of these ***,we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs.

关键词： non-human primates cell therapy stem cell

Long-term in vivo chimeric cells tracking in non-human primate

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Protein & Cell 2024年第3期15卷 207-222页

作者： Junmo Wu Yu Kang Xiang Luo Shaoxing Dai Yuxi Shi Zhuoyao li Zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang zifan li Hong Wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Yunnan Key Laboratory of Primate Biomedical Research Kunming 650500China Faculty of life Science and Technology Kunming University of Science and TechnologyKunming 650500China

Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology ***,given the ethical issues and costs associated with this model,it would be highly advantageous to use NHP cellular models in clinical ***,developing and maintaining the naive state of primate pluripotent stem cells(PSCs)remains difficult as does in vivo detection of PSCs,thus limiting biotech-nology application in the cynomolgus ***,we report a chemically defined,xeno-free culture system for culturing and deriving monkey PSCs in *** cells display global gene expression and genome-wide hypometh-ylation patterns distinct from monkey-primed *** also found expression of signaling pathways components that may increase the potential for chimera *** for biomedical applications,we were also able to integrate bioluminescent reporter genes into monkey PsCs and track them in chimeric embryos in vivo and in *** engineered cells retained embryonic and extra-embryonic developmental ***,we generated a chimeric monkey carrying bioluminescent cells,which were able to track chimeric cells for more than 2 years in living *** study could have broad utility in primate stem cell engineering and in utilizing chimeric monkey models forclinical studies.

关键词： pluripotent stem cells bioluminescence imaging non-human primates

Generation of a Hutchinson-Gilford progeria syndrome monkey model by base editing

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Protein & Cell 2020年第11期11卷 809-824页

作者： Fang Wang Weiqi Zhang Qiaoyan Yang Yu Kang Yanling Fan Jingkuan Wei Zunpeng liu Shaoxing Dai Hao li zifan li lizhu Xu Chu Chu Jing Qu Chenyang Si Weizhi Ji Guang-Hui liu Chengzu Long Yuyu Niu Yunnan Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Faculty of life Science and Technology Kunming University of Science and TechnologyKunming 650500China Institute for Stem Cell and Regeneration Chinese Academy of ScienceBeijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China China National Center for Bioinformation Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China The Leon H Charney Division of Cardiology New York University School of MedicineNew YorkNY 10016USA State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric DisordersXuanwu Hospital Capital Medical UniversityBeijing 100053China Department of Neuroscience and Physiology New York University School of MedicineNew YorkNY 10016USA Department of Neurology New York University School of MedicineNew YorkNY 10016USA

Many human genetic diseases,including Hutchinson-Gilford progeria syndrome(HGPS),are caused by single point *** is a rare disorder that causes premature aging and is usually caused by a de novo point mutation in the LMNA *** editors(BEs)composed of a cytidine deaminase fused to CRISPR/Cas9 nickase are highly efficient at inducing C to T base conversions in a programmable manner and can be used to generate animal disease models with single amino-acid ***,we generated the first HGPS monkey model by delivering a BE mRNA and guide RNA(gRNA)targeting the LMNA gene via microinjection into monkey *** out of six newborn monkeys carried the mutation specifically at the target *** monkeys expressed the toxic form of lamin A,progerin,and recapitulated the typical HGPS phenotypes including growth retardation,bone alterations,and vascular ***,this monkey model genetically and clinically mimics HGPS in humans,demonstrating that the BE system can efficiently and accurately generate patient-specific disease models in non-human primates.

关键词： base editing non-human primate HGPS