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动力学计算与模拟

中国科学：物理学、力学、天文学 2024年第4期54卷 25-30页

作者：李新征赵瑾孟胜龚新高北京大学物理学院北京100871 中国科学技术大学物理系合肥230026 中国科学院物理研究所北京100190 复旦大学物理学系上海200438

动力学计算与模拟致力于从基本物理定律出发,再现或预测凝聚态系统的时间演化过程.它不仅可以帮助人们在微观层面理解实验中观测到的动力学性质,也可以帮助人们设计具有特殊动力学性质的新型材料.本文以动力学计算与模拟为题,基于“计... 详细信息

动力学计算与模拟致力于从基本物理定律出发,再现或预测凝聚态系统的时间演化过程.它不仅可以帮助人们在微观层面理解实验中观测到的动力学性质,也可以帮助人们设计具有特殊动力学性质的新型材料.本文以动力学计算与模拟为题,基于“计算物理”新学科代码设置时对该研究方向的规划,综述其中相关研究进展,探讨新兴领域,并对其未来发展进行展望.

关键词：计算物理动力学申请代码研究方向国家自然科学基金

新媒体时代传统文化融入高职院校思政教育研究

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湖北开放职业学院学报 2024年第3期37卷 94-95,98页

作者：李正心福建农业职业技术学院福建福州350007

传统文化在高职院校思政教育中的融入具有重要意义,但面临诸多挑战,如理念滞后、互动性不足和技术应用浅显。在新媒体时代,有效地将传统文化融入思政教育,不仅能提高信息传播效率,激发学生兴趣,还能丰富教学资源,促进个性化学习,增强学... 详细信息

传统文化在高职院校思政教育中的融入具有重要意义,但面临诸多挑战,如理念滞后、互动性不足和技术应用浅显。在新媒体时代,有效地将传统文化融入思政教育,不仅能提高信息传播效率,激发学生兴趣,还能丰富教学资源,促进个性化学习,增强学生的创造力,并拓宽文化交流的平台。为应对挑战并利用新媒体时代的优势,高职院校应该利用新媒体工具创新传统文化教学方法,增强学生的文化体验、强化新媒体环境下的师生互动,促进学生对传统文化更深层次的理解、拓展跨学科项目,在创新实践中认识并重视传统文化、加强学生对传统文化的情感体验,提升学生对传统文化的认同和传承的责任感等对策,有效地将传统文化融入思政教育,促进学生全面发展。

关键词：新媒体传统文化高职院校思政教育

Escape probability based routing for ad hoc networks

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Journal of Systems Engineering and Electronics 2006年第4期17卷 927-930,937页

作者： Zhang Xuanping Qin zheng li xin Dept. of Computer Science Xi'an Jiaotong Univ. Xi'an 710049 P. R. China

Routes in an ad hoc network may fail frequently because of node mobility. Stability therefore can be an important element in the design of routing protocols. The node escape probability is introduced to estimate the lifetime and stability of link between neighboring nodes and the escape probability based routing （EPBR） scheme to discover stable routes is proposed. Simulation results show that the EPBR can discover stable routes to reduce the number of route rediscovery, and is applicable for the situation that has highly dynamic network topology with broad area of communication.

关键词： ad hoc networks escape probability routing path stability.

细菌培养法、免疫层析法及实时荧光定量PCR法在孕晚期B族链球菌筛查中的应用对比研究

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四川生理科学杂志 2024年第5期46卷 1098-1100页

作者：林莎莎李政辛李卫宁安阳市妇幼保健院检验科河南安阳455000

目的:研究细菌培养法、免疫层析法及实时荧光定量PCR法在孕晚期B族链球菌(Group B Streptococcus,GBS)筛查中的应用价值。方法:选取2021年3月至2023年5月在我院接受产检的孕晚期孕妇154例。以病理活检为金标准,分析GBS筛查结果;对比细... 详细信息

目的:研究细菌培养法、免疫层析法及实时荧光定量PCR法在孕晚期B族链球菌(Group B Streptococcus,GBS)筛查中的应用价值。方法:选取2021年3月至2023年5月在我院接受产检的孕晚期孕妇154例。以病理活检为金标准,分析GBS筛查结果;对比细菌培养法、免疫层析法及实时荧光定量PCR法单独及联合诊断孕晚期GBS的效能;分析细菌培养法、免疫层析法及实时荧光定量PCR法单独及联合筛查与病理筛查结果的一致性。结果:154例孕晚期孕妇中,经病理活检检出39例孕妇GBS为阳性;三者联合诊断GBS的灵敏度、特异度、准确率、阳性预测值以及阴性预测值均高于细菌培养法、免疫层析法与实时荧光定量PCR法单独检测(P<0.05);三者联合检测与病理结果的Kappa值为0.936,均高于细菌培养法、免疫层析法、实时荧光定量PCR法单独检测。结论:在筛查孕晚期孕妇GBS中,实时荧光定量PCR法联合细菌培养法、免疫层析法诊断效能高于单独检测,可通过三者联合检测为早期诊断孕妇是否感染GBS提供依据。

关键词：细菌培养免疫层析实时荧光定量PCR 孕晚期 B族链球菌

Chloride channels are involved in sperm motility and are downregulated in spermatozoa from patients with asthenozoospermia

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Asian Journal of Andrology 2017年第4期19卷 418-424页

作者： Shan-Wen liu Yuan li li-li Zou Yu-Tao Guan Shuang Peng li-xin zheng Shun-Mei Deng lin-Yan Zhu li-Wei Wang li-xin Chen Department of Pharmacology Medical College Jinan University Guangzhou China Department of Pathology and Pathophysiology Medical College Jinan University Guangzhou China Department of Physiology Medical College Jinan University Guangzhou China Male Reproductive Center Family Planning Special Hospital of Guangdong Guangzhou China

Human spermatozoa encounter an osmotic decrease from 330 to 290 mOsm I-z when passing through the female reproductive tract. We aimed to evaluate the role of chloride channels in volume regulation and sperm motility from patients with asthenozoospermia. Spermatozoa were purified using Percoll density gradients. Sperm volume was measured as the forward scatter signal using flow cytometry. Sperm motility was analyzed using computer-aided sperm analysis （CASA）. When transferred from an isotonic solution （330 mOsm I-z） to a hypotonic solution （290 mOsm I-Z）, cell volume was not changed in spermatozoa from normozoospermic men; but increased in those from asthenozoospermic samples. The addition of the chloride channel blockers, 4,4＇-diisothiocyanatostilbene-2,2＇- isulfonic acid （DIDS） or 5-nitro-2-（3-phenylpropylamino） benzoic acid （NPPB） to the hypotonic solution caused the normal spermatozoa to swell but did not increase the volume of those from the asthenozoospermic semen. DIDS and NPPB decreased sperm motility in both sets of semen samples. The inhibitory effect of NPPB on normal sperm motility was much stronger than on spermatozoa from the asthenozoospermic samples. Both sperm types expressed CIC-3 chloride channels, but the expression levels in the asthenozoospermic samples were much lower, especially in the neck and mid-piece areas. Spermatozoa from men with asthenozoospermia demonstrated lower volume regulating capacity, mobility, and CIC-3 expression levels （especially in the neck） than did normal spermatozoa. Thus, chloride channels play important roles in the regulation of sperm volume and motility and are downregulated in cases of asthenozoospermia.

关键词： asthenozoospermia chloride channels CIC-3 sperm motility volume regulation

基于混合自然启发算法的电网自适应过流保护优化研究

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自动化技术与应用 2024年第9期43卷 34-37,46页

作者：李正新陈斗沙李波顾健罗琨贵州电网有限责任公司毕节供电局贵州毕节551700

电力系统继电保护是现代能源电网中确保系统安全的一项重要任务。针对电网自适应保护和保护优化进行深入研究,提出一种新型聚类概念的自适应保护实现方法。采用混合自然启发算法进行保护设置优化,其中自适应保护用于应对电网系统拓扑变... 详细信息

电力系统继电保护是现代能源电网中确保系统安全的一项重要任务。针对电网自适应保护和保护优化进行深入研究,提出一种新型聚类概念的自适应保护实现方法。采用混合自然启发算法进行保护设置优化,其中自适应保护用于应对电网系统拓扑变化,优化技术用于计算保护定值,进而配合电网备用保护提供更快的故障清除。设计的测试系统采用改进IEEE14总线系统,对故障清除性能进行了测试验证,该算法相较传统算法性能优异,且自适应过电流保护的聚类方法能够有效减少继电器设置组的数量。

关键词：混合自然启发算法聚类保护定值自适应保护

Nonreciprocal generation of Schrodinger cat state induced by topology

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 23-30页

作者： Zi-Hao li li-li zheng Ying Wu xin-You Lü School of Physics and Institute for Quantum Science and Engineering Huazhong University of Science and Technologyand Wuhan Institute of Quantum TechnologyWuhan 430074China Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education Jianghan UniversityWuhan 430074China

The Schrodinger cat state produced differently in two directions is anticipated to be a critical quantum resource in quantum information *** exploring the interplay between quantum nonreciprocity and topology in a one-dimensional microcavity array,we obtain the Schrodinger cat state(a pure quantum state)in a chosen direction at the edge cavity,whereas a classical state in the other *** nonreciprocal generation of the cat state originates from the topologically protected chiralitymode excitation in the nontrivial phase,but in the trivial phase,the nonreciprocal generation of cat state ***,our proposal is switchable by tuning the parameters so that a topological phase transition ***,the obtained cat state has nonreciprocal high fidelity,nonclassicality,and quantum coherence,which are sufficient to be used in various one-way quantum technologies,e.g.,invisible quantum sensing,noise-tolerant quantum computing,and chiral quantum *** work provides a general approach to control quantum nonreciprocities with the topological effect,which substantially broadens the fields of nonreciprocal photonics and topological physics.

关键词： Schr?dinger cat state nonreciprocity topology

Directed Molecular Evolution of Nitrite Oxido-reductase by DNA-shuffling

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Biomedical and Environmental Sciences 2007年第2期20卷 113-118页

作者： JUN-WEN li JIN-LAI zheng xin-WEI WANG MIN JIN FU-HUAN CHAO Institute of Environment and Health 1 Dali Road Tianjin 300050 China

Objective To devellop directly molecular evolution Of nitrite oxido-reductase using DNA-shuffling technique because nitrobacteria grow extremelly slow and are unable to nitrify effectively inorganic nitrogen in wastewater treatmem. Methods The norB gene coding the ntitrite oxido-reductase in nitrobacteria was cloned and sequenced. Then, directed molecular evolution of nitrite oxido-reductase was developed by DNA-shuffling of 15 norB genes from different nitrobacteria. Results After DNA-shuffling with sexual PeR and staggered extension process PCR, the sequence was differem from its parental DNA fragmems and the homology ranged from 98% to 99%. The maximum nitrification rate of the modified bacterium of X16 by DNA-shuffling was up to 42.9 mg/L.d, which was almost 10 times higher than that of its parental bacteria. Furthermore, the modified bacterium had the same characteristics of its parental bacteria of E. coli and could grow rapidly in normal cultures. Conclusion DNA-shuffling was successfully used to engineer E. coli, which had norB gene and could degrade inorganic nitrogen effectively.

关键词： Directed evolution DNA-shuffling Nitrite oxido-reductase norB gene Nitrobacteria

基于继电保护的配网管理终端自动调试校准系统

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自动化技术与应用 2024年第7期43卷 150-153页

作者：李正新曲斌斌陈斗沙李波周坤贵州电网有限责任公司毕节供电局贵州毕节551700

由于系统存在误差大等问题,设计一种基于继电保护的配网管理终端自动调试校准系统。主要对系统的整体硬件结构进行优化,并重新设计继电保护装置结构以及信息传输流程,针对交直流电压的变换信息,确定继电保护装置内部电路。对校准系统工... 详细信息

由于系统存在误差大等问题,设计一种基于继电保护的配网管理终端自动调试校准系统。主要对系统的整体硬件结构进行优化,并重新设计继电保护装置结构以及信息传输流程,针对交直流电压的变换信息,确定继电保护装置内部电路。对校准系统工作中存在的粗大误差利用拉依达准则进行识别并剔除,列举部分情况下的拉依达准则判别系数,设计系统智能通信模块,完善继电保护输出流程。实验结果表明,利用所提方法的各个检测项目输出电压的误差均在允许范围之内,其自动调试校准系统更具有效性。

关键词：继电保护配电网管理终端自动调试校准系统设计