检索结果-南通市图书馆

Antibacterial and antioxidant bifunctional hydrogel based on hyaluronic acid complex MoS_(2)-dithiothreitol nanozyme for treatment of infected wounds

引用

Regenerative Biomaterials 2024年第4期3卷 98-110页

作者： yongping Lu Weiqi Kang Yue Yu ling liang Jinrong li Haiying Lu Ping Shi Mingfang He Yuemin Wang Jianshu li Xingyu Chen Guangyuan Central Hospital Guangyuan 628000P.R.China State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan UniversityChengdu 610065P.R.China Institute of Biomedical Engineering College of MedicineSouthwest Jiaotong UniversityChengdu 610031P.R.China

Wound repair is a complex physiological process that often leads to bacterial infections,which significantly threaten human ***,developing wound-healing materials that promote healing and prevent bacterial infections is *** this study,the coordination interaction between sulfhydryl groups on dithiothreitol(DTT)and MoS_(2)nanosheets is investigated to synthesize a MoS_(2)-DTT nanozyme with photothermal properties and an improved free-radical scavenging ***-bond-modified hyaluronic acid is used as a monomer and is cross-linked with a PF127-DA *** is prepared in coordination with MoS_(2)-DTT as the functional *** hydrogel exhibits antioxidant and antibacterial properties,attributed to the catalytic activity of catalase-like enzymes and photothermal *** the near-infrared(NIR),it exhibits potent antibacterial effects against gram-positive(Staphylococcus aureus)and gram-negative bacteria(Escherichia coli),achieving bactericidal rates of 99.76%and 99.42%,***,the hydrogel exhibits remarkable reactive oxygen species scavenging and antioxidant capabilities,effectively countering oxidative stress in L929 ***,in an animal model,wounds treated with the PHMoD(2.0)and NIR laser heal the fastest,sealing completely within 10 *** results indicate the unique biocompatibility and bifunctionality of the PHMoD,which make it a promising material for wound-healing applications.

关键词： hydrogel wound repair antibacterial antioxidant nanozyme photothermal therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Space Environment Measurements and Applications on the Tianhe Core Module of China Space Station

引用

空间科学学报 2022年第4期42卷 744-753页

作者： liU Siqing SUN Yueqiang ZHONG Qiuzhen WEI Fei liN Ruilin li Zhitao REN Tingling li yongping ZHANG Xianguo ZHANG Shenyi LUO Bingxian CHANG Zhen WANG Chunqin PENG Songwu AI Jiangzhao State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190 Key Laboratory of Science and Technology on Environmental Space Situation Awareness Chinese Academy of SciencesBeijing 100190 University of Chinese Academy of Sciences Beijing 100049

Tianhe Core Module of China Space Station(CSS)equips a set of instruments consisting of a Particle Fluxes and Solar Activity Detector(PFSAD)and two Atmospheric Density Multi-directional Detectors(ADMDs).The PFSAD is to measure X-rays from the Sun and energetic particles in the low-latitude and low altitude regions,including electrons,protons,and helium *** ADMDs are to measure thermospheric atmospheric *** instruments provide real-time data of the orbital space environment,including solar flares,energetic particle variation and thermospheric density *** the data contribute to the CSS space weather service for mission control and astronaut’s *** paper gives preliminary analyses of the space environment measurements from the PFSAD and the *** further analysis,the 1024-channel fine spectra of the solar X-ray can be used to study the mechanism of solar flares and their impacts on the Earth’s *** accumulation will be helpful for analyzing mid-term and long-term variations of the South Atlantic Anomaly and atmosphere ***,the data are useful to calibrate previous empirical models and establish new models to study the space environment.

关键词： Space environment Tianhe core module China Space Station(CSS)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

UVR8-TCP4-LOX2 module regulates UV-B tolerance in Arabidopsis

引用

Journal of Integrative Plant Biology 2024年第5期66卷 897-908页

作者： Cheng li Jiancan Du Huini Xu Zhenhua Feng Caspar CCChater Yuanwen Duan yongping Yang Xudong Sun Yunnan Key Laboratory of Crop Wild Relatives Omics The Germplasm Bank of Wild SpeciesKunming Institute of BotanyChinese Academyof SciencesKunming 650201China University of Chinese Academy of Sciences Beijing 100049China CAs Key Laboratory of Tropical Plant Resources and Sustainable Use Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesKunming 650223China Faculty of life Science and Technology Kunming University of Science and TechnologyKunming 650031China Royal Botanic Gardens KewRichmondSurrey TW93AEUK

The phytohormone jasmonate(JA)coordinates stress and growth responses to increase plant survival in unfavorable *** JA can enhance plant UV-B stress tolerance,the mechanisms underlying the interaction of UV-B and JA in this response remain *** this study,we demonstrate that the UV RESISTANCE LOCUS 8-TEOSINTE BRANCHED1,Cycloidea and PCF 4-liPOXYGENASE2(UVR8-TCP4-LOX2)module regulates UV-B tolerance dependent on JA signaling pathway in Arabidopsis *** show that the nucleus-localized UVR8 physically interacts with TCP4 to increase the DNA-binding activity of TCP4 and upregulate the JA biosynthesis gene ***,UVR8 activates the expression of LOX2 in a TCP4-dependent *** genetic analysis also provides evidence that TCP4 acts downstream of UVR8 and upstream of LOX2 to mediate plant responses to UV-B *** results illustrate that the UV-B-dependent interaction of UVR8 and TCP4 serves as an important UVR8-TCP4-LOX2 module,which integrates UV-B radiation and JA signaling and represents a new UVR8 signaling mechanism in plants.

关键词： anthocyanin accumulation jasmonic acid TCP4 UV-B UVR8

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

葡萄砧木新品种云砧4号的选育

引用

中国果树 2024年第2期 148-150页

作者：罗仁斌张武李永平向玲亚白明第陆晓英王佩董莉李欣杰孙继亮楚雄彝族自治州农业科学院云南675000 云南省绿色食品发展中心云南省农业科学院热区生态农业研究所

云砧4号是以云葡2号为母本、以抗砧3号为父本杂交选育的葡萄砧木新品种。长势旺盛,枝条粗壮,节间较短,萌芽率高,成枝力强,根系比抗砧3号、3309M、SO4、5BB、225Ru等传统砧木分布深而发达,较耐高温、耐旱、耐酸、耐盐碱,与诸多鲜食和酿... 详细信息

云砧4号是以云葡2号为母本、以抗砧3号为父本杂交选育的葡萄砧木新品种。长势旺盛,枝条粗壮,节间较短,萌芽率高,成枝力强,根系比抗砧3号、3309M、SO4、5BB、225Ru等传统砧木分布深而发达,较耐高温、耐旱、耐酸、耐盐碱,与诸多鲜食和酿酒品种嫁接亲和性好,能明显增强接穗品种的长势,并提高接穗品种的产量和品质。适宜在极端最低气温≥-18℃,平均年降水量≤1 500 mm,没有葡萄根瘤蚜为害的地区作砧木大面积推广应用,也可作城镇、庭院绿化树种。

关键词：葡萄新品种杂交云砧4号

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of Hematoxylin-eosin Staining and Methyl Violet Staining for Displaying Ghost Cells

引用

Eye Science 2013年第3期28卷 140-143页

作者： Wenxin Zhang yongping li Jianxian lin Shangtao Wan Huanhuan Gao Lanzhi Zhang Jianliang Zheng Ping Zhang State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University

Purpose:.To compare the merits and limitations of hematoxylin-eosin(HE) and methyl violet staining for displaying ghost cells from vitreous or aqueous ***:.A specimen containing ghost cells was adjusted to five different concentrations:(12×104,.10×104,.8×104, 6×104and 4×104cells / ml) and subjected to smearing and methyl violet and HE staining..The staining results were observed by light ***: The ghost cells were readily observed at a cell density of > 8×104cells / ml with methyl violet staining,.but only a few cells were occasionally seen at lower cell densities..In contrast,.ghost cells were seen at all cell densities with HE ***: Methyl violet staining is more rapid and simpler for the identification of ghost cells, but its staining color more readily fades, the slides cannot be stored, and it is only effective at a cell density of > 8 ×104cells / ml. In contrast,.HE staining is more time-consuming but it can display cell morphology and distinguish cell components more explicitly and slides can be permanently stored. HE staining has advantages over methyl violet staining in detecting the ghost cells when the concentration is < 8×104cells / ml.

关键词：细胞密度 HE染色甲基紫苏木精显示伊红光镜观察电池组件

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development of DArT markers for a linkage map of flue-cured tobacco

引用

Chinese Science Bulletin 2013年第6期58卷 641-648页

作者： LU XiuPing GUI YiJie XIAO BingGuang li yongping TONG ZhiJun liU Yun BAI XueFei WU WeiRen XIA ling HUTTNER Eric KIliAN Adrzej FAN LongJiang Department of Agronomy Zhejiang University Yunnan Academy of Tobacco Agricultural Sciences and China Tobacco Breeding Research Center at Yunnan DArT P/L PO Box 7141YarralumlaCanberraACT 2600Australia

Tobacco(Nicotiana tabacum) is one of the most economically important nonfood crops,and flue-cured tobacco accounts for approximately 80% of world tobacco *** extremely narrow genetic diversity in the tobacco pool has led to a low efficiency of PCR-based molecular markers(such as AFLP and SSR).Diversity Arrays Technology(DArT) is a high-throughput hybridisation-based marker system that has been developed in many plants including wheat,which,like tobacco,has a complex *** this study,we developed a tobacco DArT chip that included 7680 representative sequence tags based on typical tobacco *** 1076 DArT markers of flue-cured tobacco were identified and most(82.1%) of their polymorphism information contents(PICs) were greater than *** integrated linkage map that included 851 markers(238 DArT and 613 SSR),which is the highest density map of flue-cured tobacco to date,was *** chip-based DArT system provides an alternative in high-throughput marker genotyping for tobacco.

关键词： DART 分子标记连锁图谱烤烟烟草生产遗传多样性多态信息含量标记系统

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma

引用

Food Science and Human Wellness 2024年第3期13卷 1453-1464页

作者： Mengjie liu Xuqiang liu Kaiyue He yongping Jian Yujia li Jinrong Guo Jingyu Yang Zhixiang Xu Wenyi Kang School of life Sciences Henan UniversityKaifeng 475004China National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Joint International Research Laboratory of Food&Medicine Resource Function Kaifeng 475004China Shenzhen Research Institute of Henan University Shenzhen 518000China

3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)is a pentacyclic triterpene mainly distributed in food and medicinal plants,which exhibits various pharmacological ***,whether these functions are attributed to eBAG or additional components in these plants remain ***,we report that eBAG exerted an inhibitory activity against hepatocellular carcinoma and esophageal cancer *** induced non-apoptotic cell death in hepatocellular carcinoma *** eBAG-induced cell death was inhibited by knock-down of autophagy related gene(ATG)5 and ATG7,by administration of 3-methyladenine,a selective autophagy inhibitor that suppresses phosphoinositide 3-kinase(PI3K),and by chloroquine,a classic autophagy flux *** demonstrated that eBAG induced an autophagy-mediated cell *** of eBAG mimicked cellular bioenergetics depletion leading to the reduction of intracellular ATP,activation of AMP-activated protein kinase(AMPK),and inhibition of ***-treatment with compound C,an AMPK inhibitor,abrogated cell death induced by *** further validated the anti-tumor effect of eBAG in the murine xenograft model of hepatocellular carcinoma and found that eBAG treatment promoted the induction of autophagy and reduction of tumor growth in *** a functional food ingredient,eBAG is a potential therapeutic agent for the treatment of hepatocellular carcinoma and esophageal cancer.

关键词： eBAG Autophagy ATP AMPK Hepatocellular carcinoma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

替罪羊原型:屠龙故事真相新探

引用

外国文学研究 2017年第1期39卷 119-129页

作者：李永平陕西师范大学文学院

"屠龙"是早期人类文明的集体记忆,因此也就成为一个具有世界性的神话故事类型。为了生存或者禳除灾祸,世界早期文明体屠杀的集合体龙或者以"替罪羊"的形式献祭的象征性集合体"龙",因地域环境不同而又种类繁多。在这个过程中,不同文明之... 详细信息

"屠龙"是早期人类文明的集体记忆,因此也就成为一个具有世界性的神话故事类型。为了生存或者禳除灾祸,世界早期文明体屠杀的集合体龙或者以"替罪羊"的形式献祭的象征性集合体"龙",因地域环境不同而又种类繁多。在这个过程中,不同文明之间发生了偏移:被剪除和镇压的集合体龙和受焦虑困扰而作为替罪羊的龙逐渐分离,形成文化演进的分岔。中国连续性文明作为一个参照系,以二希为代表的文明是一个"镜像",西方对屠龙英雄的崇拜替代了对"象征性集合体"龙的崇祀,并固化为二元对立的结构模式,龙成了英雄的对立面。反观中国,在萨满教传统中,万物有灵,象征性集合体"龙"的牺牲挽救了族群,对"龙"牺牲的感恩,翻转为对龙神崇祀。以中国为代表的文明寻求天人合一,协和万邦,成就合作共赢的"命运共同体"。

关键词：屠龙龙象征性集合体文明分岔

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Factor XII (Hageman Factor) Deficiency: A Very Rare Coagulation Disorder

引用

Open Journal of Blood Diseases 2015年第4期5卷 39-42页

作者： Mohammad Arphan Azaad Qiurong Zhang yongping li Department of Clinical Medical College Dali University Dali Yunnan China

Background: Factor XII (Hageman Factor) is the initiating factor for the Intrinsic Pathway of Coagulation. Very low levels of Factor XII have been associated with increased levels of activated Partial Thromboplastin Time (aPTT). Association of Factor XII deficiency is more with thromboembolic disorders rather than bleeding tendencies. Aim: To learn more about the relationship of factor XII (Hageman Factor) deficiency and high levels of activated Partial Thromboplastin Time. Case Presentation: The Patient was admitted with complains of recurrent headaches and loin pain. Patient was incidentally found to have prolonged activated Partial Thromboplastin Time. This led to investigations which ultimately provided the evidence of severely low levels of Hageman Factor. Conclusion: Hageman Factor deficiency causes prolonged activated Partial Thromboplastin Time. However, most of the patients are asymptomatic for many years despite Hageman Factor deficiency.

关键词： Factor XII Deficiency Prolonged aPTT (Activated Partial Thromboplastin Time)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

衍射光学元件表面反射对高功率激光系统的影响

引用

中国激光 2009年第6期36卷 1371-1377页

作者：李珂刘强李永平中国科学技术大学物理系安徽合肥230026 中国科学院量子信息重点实验室安徽合肥230026

对高功率激光系统中使用的衍射光学元件(DOE)在束匀滑时产生的表面反射光场进行了模拟计算。计算表明,随着传输距离的增大,反射光由于干涉叠加会产生一定数量的光强极值点,有可能会对前端元件造成损伤。因此,在高功率激光系统应用中,有... 详细信息

对高功率激光系统中使用的衍射光学元件(DOE)在束匀滑时产生的表面反射光场进行了模拟计算。计算表明,随着传输距离的增大,反射光由于干涉叠加会产生一定数量的光强极值点,有可能会对前端元件造成损伤。因此,在高功率激光系统应用中,有必要对元件进行一定角度的倾斜放置,从而使反射光偏离前端元件。通过模拟计算分析了衍射元件放置时,倾斜角度对各项束匀滑指标的影响,发现匀滑性急剧变差,并在实验上观察到了相应的定性结果。设计了相位补偿方法,以保证倾斜放置下衍射光学元件的束匀滑能力,并给出了相位补偿的数值模拟结果。

关键词：光学器件衍射光学元件束匀滑表面反射相位补偿

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：