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脑缺血后垂体前叶促性腺激素细胞免疫组织化学和超微结构变化的实验研究

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泰山医学院学报 1996年第3期17卷 173-178页

作者：魏丽华王新成李亚鲁崔海庆孟文

应用蒙古沙土鼠制作的急性脑缺血动物模型，在５分钟和１０分钟脑缺血后，再灌注４小时～１４天，用免疫组化和电镜技术观察了不同实验组动物垂体前叶内两种促性腺激素阳性细胞的密度、染色反应和其超微结构的动态变化。结果表明：５分... 详细信息

应用蒙古沙土鼠制作的急性脑缺血动物模型，在５分钟和１０分钟脑缺血后，再灌注４小时～１４天，用免疫组化和电镜技术观察了不同实验组动物垂体前叶内两种促性腺激素阳性细胞的密度、染色反应和其超微结构的动态变化。结果表明：５分钟急性脑缺血及再灌注过程中出现的细胞密度、染色强度和超微结构的改变是暂时的、可逆的，在缺血后１周～２周内可基本恢复正常。但当脑缺血１０分钟再灌注后，垂体前叶促性腺激素细胞呈现较严重的缺血性损伤，部分细胞发生不可逆的退变反应。脑缺血后垂体前叶的促性腺激素细胞的病理损害是血清中促性腺激素含量变化的形态学基础。

关键词：脑缺血促性腺激素细胞免疫组织化学超微结构

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庆大霉素对豚鼠耳蜗ACP的影响

泰山医学院学报 1998年第2期19卷 108-110页

作者：李亚鲁康颂健史献君

目的观察庆大霉素对豚鼠耳蜗ＡＣＰ的影响。方法以耳廓反射及酸性磷酸酶（ＡＣＰ）为指标、观察正常及庆大霉素耳中毒豚鼠的耳蜗组织。结果正常豚鼠耳蜗内ＡＣＰ主要集中在耳蜗的毛细胞内，并显示出毛细胞的排列形式；庆大霉素耳中毒的... 详细信息

目的观察庆大霉素对豚鼠耳蜗ＡＣＰ的影响。方法以耳廓反射及酸性磷酸酶（ＡＣＰ）为指标、观察正常及庆大霉素耳中毒豚鼠的耳蜗组织。结果正常豚鼠耳蜗内ＡＣＰ主要集中在耳蜗的毛细胞内，并显示出毛细胞的排列形式；庆大霉素耳中毒的豚鼠耳蜗毛细胞内ＡＣＰ出现位移、显色变淡或消失。耳廓反射阈值增加越明显者，ＡＣＰ变化越显著。结论实验表明庆大霉素引起的耳蜗毛细胞的损坏与耳蜗毛细胞内溶酶体膜破裂释放出的ＡＣＰ等水解酶的自溶性损坏有关。

关键词：酸性磷酸酶庆大霉素耳毒性

Effect of geometrical configurations on alkaline air-breathing membraneless microfluidic fuel cells with cylinder anodes

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Science China(Technological Sciences) 2019年第3期62卷 388-396页

作者： ZHANG Biao WANG HaoNan ZHU Xun YE DingDing liAO Qiang SUI PangChieh DJILAli Ned JIANG li FU yalu Key Laboratory of Low-Grade Energy Utilization Technologies and Systems Chongqing University Institute of Engineering Thermophysics Chongqing University School of Automotive Engineering Wuhan University of Technology Department of Mechanical Engineering and Institute for Integrated Energy Systems (IESVic) University of Victoria

Membraneless microfluidic fuel cells(MMFCs) outperform traditional membrane-based micro-fuel cells in membraneless architecture and high surface-to-volume ratio and facile integration, but still need substantial improvement in performance. The fundamental challenges are dictated by multiphysics regarding cell configurations: the interaction of fluid flow, mass transport and electrochemical reactions. We present a numerical research that investigates the effect of geometrical configurations(rod arrangement, cell length, rod diameter and spacer configuration) on the fuel transport and performance of an alkaline MMFC with cylinder anodes. Modeling results suggest that the staggered rod arrangement outperforms the in-line case by 10.1% at 50 μL min^(–1). Cell power output and power density vary nearly linearly with the cell length. In the case with 0.7 mm anodes and 0.3 mm spacers, the increased flow resistance at anode region drives the fuel to intrude into the spacer zone, leading to fuel transport limitation at downstream. The feasibility of non-spacer configuration is demonstrated, and the power density is 93.7% higher than the baseline due to reduced cell volume and enhanced fuel transport. In addition, horizontal extension of the anode array is found to be more favorable for scale-up, the maximum power density of 181.9 mW cm^(–3) is predicted. This study provides insight into the fundamental, and offers guidance to improve the cell design for promoting performance and facilitating system integration.

关键词： microfluidic fuel cell cylinder anode mass transport cell configuration computational model

青、老年小鼠体外血栓的比较及左归饮加减对体外血栓的影响

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泰山医学院学报 1996年第1期17卷 10-11页

作者：刘传军王洪海崔海庆李亚鲁高慧英泰安市第三人民医院

昆明种小鼠３２只，其中老年鼠２４只（１８～２４个月）分成Ａ、Ｂ两组；青年鼠（３～４个月）８只为Ｃ组。Ａ组小鼠饮用左归饮加减的常规汤剂７５天后，各组小鼠均取血１ｍｌ，以国产ＤＪＨ型单环血栓仪进行体外血栓监测。结果：Ａ、... 详细信息

昆明种小鼠３２只，其中老年鼠２４只（１８～２４个月）分成Ａ、Ｂ两组；青年鼠（３～４个月）８只为Ｃ组。Ａ组小鼠饮用左归饮加减的常规汤剂７５天后，各组小鼠均取血１ｍｌ，以国产ＤＪＨ型单环血栓仪进行体外血栓监测。结果：Ａ、Ｂ两组体外血栓的长度和重量明显高于青年组（Ｐ＜０．０１），Ａ组低于Ｂ组（Ｐ＜０．０５）。实验结果表明，小鼠的体外血栓随增龄而增长和增重，证明左归饮加减而成的汤剂有明显改善血液循环的作用。

关键词：小鼠体外血栓左归饮

近距离煤层群协同机理对下位煤层巷道围岩应力研究

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江西煤炭科技 2024年第4期 57-62页

作者：刘国艳刘龙石磊贾传宝李雅禄张天依巩佳易孙耀辉秦桐吕梁学院矿业工程系山西吕梁033001 中国矿业大学(北京) 北京100083 国能包头能源有限责任公司李家壕煤矿内蒙古鄂尔多斯017000

针对山西西易煤矿近距离4-1煤层、4^(-2)煤层,上位4-1煤层遗留煤柱对底板应力集中问题,讨论下位4^(-2)煤层巷道布置特征。通过塑性理论计算得出遗留煤柱对底板影响深度为25 m,大于上、下煤层夹层厚度,并计算得出遗留煤柱对底板横向影响... 详细信息

针对山西西易煤矿近距离4-1煤层、4^(-2)煤层,上位4-1煤层遗留煤柱对底板应力集中问题,讨论下位4^(-2)煤层巷道布置特征。通过塑性理论计算得出遗留煤柱对底板影响深度为25 m,大于上、下煤层夹层厚度,并计算得出遗留煤柱对底板横向影响范围为33.9~39.9 m。基于FLAC3D数值模拟分析下位4^(-2)煤层三种巷道位置布置方案,得出巷道布置在采空区最有利。综合分析遗留煤柱应力影响范围和数值模拟方案,得出下位4^(-2)煤层巷道外错40 m最为合理,且利于相邻工作面巷道布置。同时,提出采用“工字钢棚+锚杆+金属网”联合支护形式,在掘进和回采期间巷道稳定性较好,能保证正常矿井生产。

关键词：近距离煤层群遗留煤柱应力集中采空区巷道布置

Lowing the energy loss of organic solar cells by molecular packing engineering via multiple molecular conjugation extension

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Science China Chemistry 2022年第7期65卷 1362-1373页

作者： Hongbin Chen yalu Zou Huazhe liang Tengfei He Xiaoyun Xu Yunxin Zhang Zaifei Ma Jing Wang Mingtao Zhang Quanwen li Chenxi li Guankui Long Xiangjian Wan Zhaoyang Yao Yongsheng Chen State Key Laboratory and Institute of Elemento-Organic Chemistry Centre of Nanoscale Science and Technology and Key Laboratory of Functional Polymer MaterialsRenewable Energy Conversion and Storage Center(RECAST)College of ChemistryNankai UniversityTianjin 300071China School of Materials Science and Engineering National Institute for Advanced MaterialsRenewable Energy Conversion and Storage Center(RECAST)Nankai UniversityTianjin 300350China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Center for Advanced Low-dimension MaterialsCollege of Materials Science and EngineeringDonghua UniversityShanghai 201620China School of Materials Science&Engineering Tianjin University of TechnologyTianjin 300384China

The central unit(benzo[c][1,2,5]thiadiazole) in Y6 series of molecules plays a determining role in their unique intermolecular packing for a three-dimensionally(3D) network, largely endowing their organic solar cells(OSCs) with so far the best power conversion efficiencies(PCEs) and also largely suppressed energy losses(Eloss). Despite its vital role in molecular packing, very few explorations for central unit have been conducted due to possibly the constructing challenge of central heterocyclic ***, a highly efficient acceptor-donor-acceptor(A-D-A) type electron acceptor, CH17, has been designed and constructed,featured with a prominent π extension in both directions of the central and end units with respect to Y6 series. Such a multiple and much enhanced conjugation extension in CH17 enables a much more effective and compact 3D molecular packing compared with that of Y6 supported by X-ray single crystal and other analysis, mainly caused by a newly observed distinctive dual “end unit to central unit” packing mode. This much favorable molecular packing, also kept in its blends with donor materials, leads a larger electron and hole transfer integrals and hence much improved charge transport, and reduced energetic disorders in CH17blends. More importantly, the observed upshifted charge transfer(CT) state of CH17 blends compared with that of Y6, due to its increased molecular conjugation extension in both directions, further enhances the hybridization between its CT and local exciton(LE) states, resulting in higher luminescence efficiency, much suppressed non-radiative recombination loss and smaller Elosswith respect to that of Y6. Consequently, an excellent PCE of 17.84% is achieved with PM6 as the donor in a binary device compared with a PCE of 16.27% for the controlled Y6 device. Furthermore, a further improved PCE of 18.13% is achieved by CH17-based ternary single-junction OSCs along with a markedly reduced Elossof 0.49 e V and larger open-circuit voltage(

关键词： organic solar cells A-D-A electron acceptor reduced Eloss central unit multiple conjugation extension molecular packing

雌性老龄小鼠饮用左归饮加减后卵巢和子宫的形态学及组织化学改变

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泰山医学院学报 1997年第2期18卷 86-89页

作者：高慧英王洪海崔海庆李亚鲁王新成

目的探讨左归饮加减对老年雌性小鼠卵巢和子宫的影响。方法雌性老年昆明种小鼠饮用左归饮加减煎剂７５ｄ后，取卵巢和子宫进行形态学和细胞化学研究。结果服药小鼠的卵巢内卵泡生长发育过程活跃，卵泡膜内层细胞及基质细胞内３β—ＨＳ... 详细信息

目的探讨左归饮加减对老年雌性小鼠卵巢和子宫的影响。方法雌性老年昆明种小鼠饮用左归饮加减煎剂７５ｄ后，取卵巢和子宫进行形态学和细胞化学研究。结果服药小鼠的卵巢内卵泡生长发育过程活跃，卵泡膜内层细胞及基质细胞内３β—ＨＳＤＨ阳性反应细胞增多，反应增强，子宫壁增厚，ＰＡＳ（＋）和ＡＢ（＋）细胞明显增多，反应增强。结论左归饮加减有明显的改善老年小鼠卵巢和子宫功能的作用。

关键词：左归饮小鼠卵巢子宫药理

Integrated and holistic knowledge map of phase change materials for pavement: A scientometric analysis and bibliometric review

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第6期11卷 1317-1339页

作者： Jiasheng Dai Feng Ma Zhen Fu Chen li Yingjie Hou yalu Wen Yanzhe Zou Dongdong Yuan Wenhao Dong Ke Shi Key Laboratory for Special Area Highway Engineering of Ministry of Education Chang'an University School of Materials Science and Engineering Chang'an University

Elevated pavement temperatures contribute to the urban heat island effect and pose a risk of thermal damage to pavement. Thus, regulating pavement temperature is paramount to ensure its longevity, enhance traffic safety, and preserve the environment. Phase change materials(PCMs) with the latent heat characteristic can store and release thermal energy via phase transitions. PCMs can effectively control pavement structure temperatures within a relatively narrow range, mitigating thermal stress on asphalt pavements. This research aims to explore the current status and emerging trends in PCM integrated pavement engineering(PCMIPE) using the CiteSpace visual analysis tool. Relevant publications were systematically curated from the Web of Science core database, spanning 2011to 2023. Subsequently, the co-authorships network maps(country, institution, author), cocited network maps(co-cited journals, authors, and references), and keyword co-occurrence network maps were constructed to analyze the principal contributions in the PCMIPE field comprehensively. This analysis provides an understanding of the field's strengths,research domains, and knowledge structure and identifies current research focal points and emerging frontiers. The findings reveal that research within the PCMIPE field is still in its early stages, with a predominant emphasis on material design and performance assessment. Additionally, future research is anticipated to expand into economic analyses and exploration of environmental effects when integrating PCMs into pavement engineering. Furthermore, there is an emerging interest in investigating the synergy of PCMs with other functional pavement technologies. These results underscore the potential of the PCMIPE field and emphasize the importance of future research endeavors.

关键词： Road engineering Phase change materials Pavement CiteSpace Visualization analysis

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左归饮加减对小鼠肝细胞内SOD的影响

泰山医学院学报 1995年第2期16卷 86-87页

作者：王洪海马培珍高慧英安蔚崔海庆李亚鲁

本试验选用昆明种小鼠３２只，其中老年小鼠（１８月～２２个月）２４只，分为Ａ、Ｂ两组，Ｃ组为青年小鼠（２个月）８只，以中药方剂左归饮加减的水煎液给Ａ组小鼠自由饮用。７５天后，与Ｂ组相比活力增加，毛色光亮，肝细胞内ＳＯＤ... 详细信息

本试验选用昆明种小鼠３２只，其中老年小鼠（１８月～２２个月）２４只，分为Ａ、Ｂ两组，Ｃ组为青年小鼠（２个月）８只，以中药方剂左归饮加减的水煎液给Ａ组小鼠自由饮用。７５天后，与Ｂ组相比活力增加，毛色光亮，肝细胞内ＳＯＤ活性明显升高（Ｐ＜０．０５）。实验证明，以左归饮为主的水煎液，可增强肝细胞内ＳＯＤ的活性，因此有明显的抗氧化、抗衰老的作用。

关键词：左归饮抗衰老小鼠超氧化物歧化酶药理