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ChinAfrica 2024年第8期16卷 31-33页

作者： TIAN JIETANG LUO liPING MA SHUAN GU YAN li yuju Industrial Economics Department Development Research Centre of the State Council Research Institute for Regional Economy and Ecological Development Hunan Academy of Social Sciences Specialised Committee on International Cooperation and Science and Technology Diplomacy Chinese Association for Science of Science and S&T Policy Research Xi Jinping Economic Thought Research Centre National Development and Reform Commission

In recent years,China has made remarkable technological progress in a number of *** this progress,it is crucial to rapidly transform technological results into productivity gains.

关键词： technological cooperation remarkable

Thinking in English is the Keylink

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兵团教育学院学报 1999年第2期9卷 84-86页

作者： li yuju\ \ li Honghui \ 兵团教院/石大师院

The article discusses the importance of thinking in English in learning English The content of thinking in English is also offered in the essay The way how to think in English is suggested in the

关键词：英语教学教学方法教学内容英语思维

Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms:relevance to excitotoxic neurodegeneration

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Translational Neurodegeneration 2017年第1期6卷 98-107页

作者： yuju li Justin Peer Runze Zhao Yinghua Xu Beiqing Wu Yi Wang Changhai Tian Yunlong Huang Jialin Zheng Center for Translational Neurodegeneration and Regenerative Therapy Shanghai Tenth People’s Hospital affiliated to Tongji University School of MedicineShanghaiChina Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical CenterOmahaNEUSA Department of Pathology and Microbiology University of Nebraska Medical CenterOmahaNEUSA Shanghai Tenth People’s Hospital affiliated with Tongji University School of Medicine Shanghai 200072China Laboratory of Neuroimmunology and Regenerative Therapy Departments of Pharmacology and Experimental Neuroscience and Pathology and Microbiology985930 Nebraska Medical CenterOmahaNE 68198-5930USA

Background:Glutaminase 1 is a phosphate-activated metabolic enzyme that catalyzes the first step of glutaminolysis,which converts glutamine into *** is the major neurotransmitter of excitatory synapses,executing important physiological functions in the central nervous *** are two isoforms of glutaminase 1,KGA and GAC,both of which are generated through alternative splicing from the same *** and GAC both transcribe 1–14 exons in the N-terminal,but each has its unique C-terminal in the coding *** have previously identified that KGA and GAC are differentially regulated during inflammatory stimulation and HIV ***,glutaminase 1 has been linked to brain diseases such as amyotrophic lateral sclerosis,Alzheimer’s disease,and hepatic *** enzyme structure of KGA and GAC has been published ***,how other coding sequences affect their functional enzyme activity remains ***:We cloned and performed serial deletions of human full-length KGA and GAC from the N-terminal and the C-terminal at an interval of approximately 100 amino acids(AAs).Prokaryotic expressions of the mutant glutaminase 1 protein and a glutaminase enzyme activity assay were used to determine if KGA and GAC have similar efficiency and efficacy to convert glutamine into ***:When 110 AAs or 218 AAs were deleted from the N-terminal or when the unique portions of KGA and GAC that are beyond the 550 AA were deleted from the C-terminal,KGA and GAC retained enzyme activity comparable to the full length *** contrast,deletion of 310 AAs or more from N-terminal or deletion of 450 AAs or more from C-terminal resulted in complete loss of enzyme activity for KGA/***,when both Nand C-terminal of the KGA and GAC were removed,creating a truncated protein that expressed the central 219 AA-550 AA,the protein retained enzyme ***,expression of the core 219 AA-550 AA coding sequence in cel

关键词： Glutaminase 1 Protein expression Enzyme activity

中国产业对外转移的特征、驱动因素与应对策略--基于“气候模型”(CliME)的分析

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宏观经济研究 2022年第5期 82-93页

作者：李玉举刘振中何杰锋国家发展改革委政策研究室中国宏观经济研究院产业经济与技术经济研究所中共中央党校(国家行政学院)理论经济学博士后流动站

本文测算2009—2018年30个制造业分行业、分地区对外直接投资数据,发现中国16类行业处于扩张期、4类处于收缩期、10类处于波动期,有四成行业发生了产业对外转移,4类行业更青睐国内市场,半数行业属于候鸟型产业。构建“气候模型”分析相... 详细信息

本文测算2009—2018年30个制造业分行业、分地区对外直接投资数据,发现中国16类行业处于扩张期、4类处于收缩期、10类处于波动期,有四成行业发生了产业对外转移,4类行业更青睐国内市场,半数行业属于候鸟型产业。构建“气候模型”分析相关因素对产业对外转移的影响,发现东道国劳动力成本越高,中国劳动密集型产业、技术密集型产业、应急型产业越难向这些国家或地区转移。东道国劳动力相对成本推动中国技术密集型产业、应急型产业的对外转移。中国产业对外转移更容易发生在东道国经济复杂度越低的国家。东道国制度环境越差,中国整体产业,特别是资本密集型产业对外转移越少。东道国市场容量越大,越不利于中国产业对外转移。金融危机导致中国产业投资倾向于国内而不是国外。建议要把产业的“根”留住,降低中国绝对成本和相对成本,加快提升中国产业链长度和经济复杂度,扩大国内市场容量,做好产业转移风险把关,构建以我为重心的全球产业链价值链。

关键词：产业转移气候模型产业链稳定制造业

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应用引力模型评判区域贸易安排与出口增长

财经科学 2005年第3期 100-106页

作者：李玉举中国社会科学院财贸所

引力模型为有效促进参与区域贸易安排成员国的出口增长提供了有力证据。通过总量和产品类别的实证分析表明,区域贸易安排对不同产品类别的出口增长的影响效果并不一致。我国参与区域贸易安排的战略选择上,还需要将引力模型得出的贸易不... 详细信息

引力模型为有效促进参与区域贸易安排成员国的出口增长提供了有力证据。通过总量和产品类别的实证分析表明,区域贸易安排对不同产品类别的出口增长的影响效果并不一致。我国参与区域贸易安排的战略选择上,还需要将引力模型得出的贸易不足和贸易过度的结论,与出口比较优势和出口收益传导机制有机结合起来。

关键词：区域贸易出口增长率引力模型中国对外贸易贸易结构

Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons

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Translational Neurodegeneration 2018年第1期7卷 307-321页

作者： Kangmu Ma Xiaobei Deng Xiaohuan Xia Zhaohuan Fan Xinrui Qi Yongxiang Wang yuju li Yizhao Ma Qiang Chen Hui Peng Jianqing Ding Chunhong li Yunlong Huang Changhai Tian Jialin C.Zheng Center for Translational Neurodegeneration and Regenerative Therapy Shanghai Tenth People’s Hospital affiliated to Tongji University School of MedicineShanghai 200072China Collaborative Innovation Center for Brain Science Tongji UniversityShanghai 200092China Departments of Pharmacology and Experimental Neuroscience University of Nebraska Medical CenterOmahaNE 68198-5930USA Department of Neurology&Institute of Neurology Ruijin Hospital affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Pathology and Microbiology University of Nebraska Medical CenterOmahaNE 68198-5930USA

Background:Cell replacement therapy has been envisioned as a promising treatment for neurodegenerative *** to the ethical concerns of ESCs-derived neural progenitor cells(NPCs)and tumorigenic potential of iPSCs,reprogramming of somatic cells directly into multipotent NPCs has emerged as a preferred approach for cell ***:Mouse astrocytes were reprogrammed into NPCs by the overexpression of transcription factors(TFs)Foxg1,Sox2,and *** generation of subtypes of neurons was directed by the force expression of cell-type specific TFs Lhx8 or Foxa2/***:Astrocyte-derived induced NPCs(AiNPCs)share high similarities,including the expression of NPC-specific genes,DNA methylation patterns,the ability to proliferate and differentiate,with the wild type *** AiNPCs are committed to the forebrain identity and predominantly differentiated into glutamatergic and GABAergic neuronal ***,additional overexpression of TFs Lhx8 and Foxa2/Lmx1a in AiNPCs promoted cholinergic and dopaminergic neuronal differentiation,***:Our studies suggest that astrocytes can be converted into AiNPCs and lineage-committed AiNPCs can acquire differentiation potential of other lineages through forced expression of specific *** the impact of the TF sets on the reprogramming and differentiation into specific lineages of neurons will provide valuable strategies for astrocyte-based cell therapy in neurodegenerative diseases.

关键词： Astrocytes iNPCs Reprogramming Transcription factor Neuronal lineage Cholinergic neurons Dopaminergic neurons Lhx8 Foxa2 Lmx1a

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东盟与区外六国的经贸格局与发展潜力

世界经济研究 2005年第12期 32-38页

作者：李玉举中国社会科学院财贸经济研究所

2002年以后,中、美、印、日、韩、澳6国相继提出与东盟组建自由贸易区。预期至 2010年左右,亚太地区将形成多个零关税的自由贸易区。本丈首先描述了自由贸易区的进展及其诱因,分析了东盟与区外6国的经贸格局和加深合作的五大差异性,并... 详细信息

2002年以后,中、美、印、日、韩、澳6国相继提出与东盟组建自由贸易区。预期至 2010年左右,亚太地区将形成多个零关税的自由贸易区。本丈首先描述了自由贸易区的进展及其诱因,分析了东盟与区外6国的经贸格局和加深合作的五大差异性,并提出了中国与东盟合作的战略选择。

关键词：东盟差异性战略选择

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混合所有制改革中的商誉与无形资产价值问题

财经科学 2018年第1期 89-98页

作者：李玉菊北京交通大学经济管理学院

推进混合所有制改革，应客观地厘清国有资产的形态和类型，除对容易辨识的有形资产进行科学估值外，还应当重视专利和商标等一般无形资产、特殊资源和政策保障资源以及商誉等的估值。应当健全国有资产估值的规则和程序，对于行业竞争性... 详细信息

推进混合所有制改革，应客观地厘清国有资产的形态和类型，除对容易辨识的有形资产进行科学估值外，还应当重视专利和商标等一般无形资产、特殊资源和政策保障资源以及商誉等的估值。应当健全国有资产估值的规则和程序，对于行业竞争性垄断地位明显的企业、行业发展相对稳定且没有明显生命周期的大型企业、品牌型和“老字号”企业、人力资源型企业等四种类型的企业，无论其是属于国有资产还是属于非公有资产，在发展混合所有制经济进行资产估值时，都必须高度重视商誉的价值评估，切不可简单化处置。

关键词：混合所有制改革无形资产商誉