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Acta Geologica Sinica(English Edition) 2024年第2期98卷 337-351页

作者： HUANG Zengbao li xiyao ZHAO Hao LU Qing Geological Survey of Gansu Province Lanzhou 735000China Key Laboratory of Submarine Geosciences and Prospecting Techniques MOE and College of Marine GeosciencesOcean University of ChinaQingdaoShandong 266100China Research Institute of Petroleum Exploration and Development Shengli OilfieldSINOPECDongyingShandong 257000China

The Triassic granitoids in Central Tianshan play a key role in determining the petrogenesis and tectonic evolution on the southern margin of the Central Asian orogenic *** this study,we present SHRIMP zircon U-Pb ages,Hf isotopic and geochemical data on the Xingxingxia biotite granite,amazonite granite and granitic pegmatite in Central Tianshan,NW *** U-Pb dating yielded formation ages of 242 Ma for the biotite granite and 240 Ma for the amazonite *** granitoid rocks have high K_(2)O with low MgO and CaO *** are enriched in Nb,Ta,Hf and Y,while being depleted in Ba and Sr,showing flat HREE patterns and negative Eu *** have typical A-type granite geochemical signatures with high Ga/A_(1)(8–13)and TFeO/(TFeO+MgO)ratios,showing an A_(2) affinity for biotite granite and an A_(1) affinity for amazonite granite and granitic *** ε_(Hf)(t)values of the granitoids are 0.45–2.66,with Hf model ages of 0.99–1.17 *** suggests that these A-type granites originated from partial melting of the lower *** propose that Xingxingxia Triassic A-type granites formed under lithospheric extension from post-orogenic to anorogenic intraplate settings and NE-trending regional strike-slip fault-controlled magma emplacement in the upper crust.

关键词： Triassic A-type granite Xingxingxia Central Tianshan Central Asian orogenic belt

Characteristics and quality of clinical practice guidelines for diabetic kidney disease: a systematic review

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Journal of Traditional Chinese Medicine 2024年第3期44卷 609-619页

作者： WANG Yuhuang ZHANG Le ZHANG Zhengshan YAO Zhi li xiyao SUN Luying liAO Xing Department of Nephropathy and Endocrine Dongzhimen HospitalBeijing University of Chinese Medicine Centre for Evidence-Based Chinese Medicine Institute of Basic Research in Clinical MedicineChina Academy of Chinese Medical Sciences Department of Endocrine One Zone Fangshan HospitalBeijing University of Chinese Medicine

OBJECTIVE: To assess the quality of Clinical practice guidelines(CPGs) in the context of diabetic kidney disease(DKD) and determine whether any factors affect the quality. METHODS: We searched eight databases along with five international and national organizations to develop or archive guidelines from their inception to July 2023, with an additional search of ***. And the authoritative organizations related to nephrology. CPGs and consensus statements created using direct differential diagnosis or therapy for DKD were included without language restrictions. Their quality was evaluated by four reviewers using the Appraisal of Guidelines for Research and Evaluation Ⅱ(AGREE Ⅱ) instrument. Along with the item and domain scores, the guideline was also allocated an overall quality score, which ranged from 1(lowest possible quality) to 7(highest possible quality). Moreover, an overall recommendation for use was also assigned(“recommended”, “recommended with modifications” or “not recommended”). RESULTS: A total of 16 CPGs were included, of which 14 were from Asia and the remaining two from Europe. These two CPGs were updated in the third version. Six CPGs were recommended for use because their primary domains scored in the medium or high category. Furthermore, five CPGs were recommended with modifications as the stakeholder involvement, applicability, and editorial independence domains were evaluated as low categories. In all domains, the lowest average score was for rigour of development(33%), followed by application(36%), and stakeholder involvement(51%). The highest average score was for scope and purpose(79%), followed by clarity of presentation(75%). None of the CPGs considered the patient's viewpoint, and six of 16 CPGs did not use any grading system to translate the evidence into recommendations. Additionally, only three of 16 CPGs shared search strategy, and eight of 16 CPGs did not declare a funding source. CONCLUSIONS: According to the AGREE II evaluation

关键词： appraisal of guidelines for research and evaluation II diabetic nephropathies practice guideline quality assessment systematic review

Early Ordovician-Middle Silurian Subduction-Closure of the Proto-Tethys Ocean:Evidence from the Qiaerlong Pluton at the Northwestern Margin of the West Kunlun Orogenic Belt,NW China

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Journal of Earth Science 2024年第2期35卷 430-448页

作者： Jinhong Xu Zhengwei Zhang Chengquan Wu Taiyi Luo Weiguang Zhu xiyao li Ziru Jin Pengcheng Hu State Key Laboratory of Ore Deposit Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang550018China University of Chinese Academy of Sciences Beijing100049China

Early Paleozoic magmatism in the West Kunlun Orogenic Belt(WKOB)preserves important information about the tectonic evolution of the Proto-Tethys *** paper reports whole-rock compositions,zircon and apatite U-Pb dating,and zircon Hf isotopes for the Qiaerlong Pluton(QEL)at the northwestern margin of WKOB,with the aim of elucidating the petrogenesis of the pluton and shedding insights into the subduction-collision process of this oceanic *** QEL is mainly composed of Ordovician quartz monzodiorite(479±3 Ma),quartz monzonite(467–472 Ma),and syenogranite(463±4 Ma),and is intruded by Middle Silurian peraluminous granite(429±20 Ma)and diabase(421±4 Ma).Zirconε_(Hf)(t)values reveal that quartz monzodiorites(+2.1 to+9.9)and quartz monzonites(+0.6 to+6.8)were derived from a mixed source of juvenile crust and older lower crust,and syenogranites(−5.6 to+4.5)and peraluminous granites(−2.9 to+2.0)were generated from a mixed source of lower crust and upper crust;diabases had zirconε_(Hf)(t)values ranging from−0.3 to+4.1,and contained 463±5 Ma captured zircon and 1048±39 Ma inherited zircon,indicating they originated from enriched lithospheric mantle and were contaminated by crustal *** Ordovician granitoids are enriched in liLEs and light rare-earth elements,and depleted in HFSEs with negative Nb,Ta,P,and Ti anomalies,suggesting that they formed in a subduction *** Silurian peraluminous granites have the characteristics of leucogranites with high SiO_(2)contents(74.92 wt.%–75.88 wt.%)and distinctly negative Eu anomalies(δEu=0.03–0.14),indicating that they belong to highly fractionated granite and were formed in a post-collision extension *** analysis of these results with other Early Paleozoic magmas reveals that the Proto-Tethys ocean closed before the Middle Silurian and its southward subduction resulted in the formation of QEL.

关键词： subduction-closure Qiaerlong Pluton West Kunlun Orogen Proto-Tethys Ocean tectonics geochemistry

Petrogenesis and Tectonic Implications of the Paleoproterozoic A-Type Granites in the Xiong’ershan Area along the Southern Margin of the North China Craton

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Journal of Earth Science 2024年第2期35卷 416-429页

作者： Jinhong Xu Yuping Jiang Shuli Hu Zhengwei Zhang Chengquan Wu Chaofei Zheng xiyao li Ziru Jin Sensen Zhang Yatao Zhou State Key Laboratory of Ore Deposit Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang550081China University of Chinese Academy of Sciences Beijing100049China Henan Province Non-ferrous Metals Geological Mineral Resources Bureau Zhengzhou450053China Jiangmen Land Market Monitoring Center Jiangmen 529000China

Paleoproterozoic A-type granites are widely distributed in the southern margin of the North China Craton(SNCC),providing important information for understanding the Paleoproterozoic tectonic regimes in this *** paper reports newly obtained whole-rock compositions and zircon U-Pb ages for the Tieluping syenogranite porphyry(TLP)and Huoshenmiao alkali granite porphyry(HSM)in the *** from the TLP and HSM have U-Pb ages of 1805±12 and 1792±14 Ma,*** ages are taken to date the emplacement of these *** had high total alkali contents(K_(2)O+Na_(2)O>7.13 wt.%),with high 10000×Ga/Al ratios(3.06–3.41)and Zr+Y+Nb+Ce values(709 ppm–910 ppm)as well as high zircon saturation temperatures(864–970℃),indicative of A-type granite *** Y/Nb(1.75–3.32),Ce/Nb(7.72–9.72),and Yb/Ta(2.89–5.60)ratios suggested that TLP and HSM belonged to the A2-type *** negative whole rockε_(Nd)(t)values(−8.4 to−6.6)and negative zirconε_(Hf)(t)values(−15.9 to−6.3)confirmed that TLP and HSM were likely generated by the partial melting of an ancient continental ***εHf(t)(−7.4 to+4.0)values of inherited zircons in the TLP suggested that they were derived from the partial melting of Archean basement *** the geochemical similarity of the 1.80 Ga A-type granitoids in the SNCC,we propose that the TLP and HSM were formed in a post-collisional regime that was likely associated with the break-off of the Paleoproterozoic subducted *** of the asthenosphere provided huge heat to generate the regional 1.80 Ga A-type granite in the SNCC.

关键词： Paleoproterozoic A-type granite Post-collisional North China Craton tectonic geochemistry

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数字化转型对企业新质生产力的影响

工业技术经济 2024年第6期43卷 12-19页

作者：张慧智李犀尧吉林大学东北亚研究中心长春130012

本文以2011~2022年上市公司为研究样本,基于数字化转型赋能新质生产力提升的深层逻辑,考察了数字化转型对企业新质生产力的影响、作用机制及异质性特征。研究发现:(1)数字化转型对企业新质生产力的发展具有显著的正向影响,数字化转型带... 详细信息

本文以2011~2022年上市公司为研究样本,基于数字化转型赋能新质生产力提升的深层逻辑,考察了数字化转型对企业新质生产力的影响、作用机制及异质性特征。研究发现:(1)数字化转型对企业新质生产力的发展具有显著的正向影响,数字化转型带来的技术创新与管理创新满足了新质生产力的催生条件;(2)不同特征的企业数字化转型对新质生产力的发展存在异质性,相对于其他类型企业,数字化转型更加有利于提升技术密集型企业、东部企业、国有企业的新质生产力,这有助于企业深刻理解新质生产力的特征并助力企业提升新质生产力;(3)机制检验结果显示,数字化转型主要通过技术创新与管理创新两个渠道促进企业新质生产力的发展,技术创新是新质生产力发展的底层支撑,而管理创新为技术创新提供了制度保障。

关键词：数字化转型新质生产力技术创新管理创新逐步回归异质性

内蒙古五当召当圪希德殿壁画色彩特征与复原再现

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艺术设计研究 2024年第1期 81-87,53页

作者：李熙瑶郭宏罗傲特根北京科技大学科技史与文化遗产研究院内蒙古包头市五当召综合保障中心

五当召位于内蒙古包头市东北部,阴山山脉的五当沟内,是全国重点文物保护单位。以当圪希德殿为代表的五当召壁画是文化交流、涵化的代表,具有重要的研究价值。由于自然和人为因素的破坏,当圪希德殿壁画出现了积尘、空鼓、起甲等多种病害... 详细信息

五当召位于内蒙古包头市东北部,阴山山脉的五当沟内,是全国重点文物保护单位。以当圪希德殿为代表的五当召壁画是文化交流、涵化的代表,具有重要的研究价值。由于自然和人为因素的破坏,当圪希德殿壁画出现了积尘、空鼓、起甲等多种病害,严重影响了壁画色彩的表达。本文通过显微共聚焦激光拉曼光谱仪和测色仪,对其壁画色彩特征进行了分析,以便为壁画的色彩修复提供理论依据。同时,我们根据五当召当圪希德殿壁画的色彩特征对其进行了复原再现,以期为其壁画的修复和后期保养提供借鉴。

关键词：内蒙古五当召壁画色彩复原再现

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铜基金属纳米多层膜界面介导的损伤及断裂行为原位研究进展

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精密成形工程 2024年第9期16卷 13-21页

作者：祁志旭岳鹏飞李习耀王江伟河南省科学院材料研究所郑州450046 河南科技大学材料科学与工程学院河南洛阳471003

作为一种典型异质结构材料,纳米金属多层膜的力学响应通常表现出界面介导的损伤及断裂行为。而基于电镜发展的原位力学测试方法,可实现多层膜变形过程中力学行为的精确刻画,从而有助于揭示其界面损伤及断裂的潜在物理机制。当前围绕纳... 详细信息

作为一种典型异质结构材料,纳米金属多层膜的力学响应通常表现出界面介导的损伤及断裂行为。而基于电镜发展的原位力学测试方法,可实现多层膜变形过程中力学行为的精确刻画,从而有助于揭示其界面损伤及断裂的潜在物理机制。当前围绕纳米多层膜的原位研究已有诸多进展。以铜基金属纳米多层膜为例,从缺陷-界面交互行为出发,基于组元层厚对位错运动的影响,详细讨论了位错塞积、约束层滑移和位错穿越3种位错-界面交互机制导致界面损伤的原位研究进展;阐述了孪晶-界面交互行为对界面损伤的影响,进一步分析了因孪生导致的界面损伤行为。在此基础上,讨论了多层膜变形过程中界面介导的裂纹萌生和扩展行为;基于界面类型、载荷加载形式和裂纹偏转等因素,详细分析了多层膜界面介导的断裂机制。最后对材料损伤断裂行为的原位研究进行了展望。

关键词：纳米金属多层膜界面损伤及断裂位错-界面交互孪晶-界面交互原位研究

单基因组扩增法分析HIV-1 CRF103_01B3′半长基因组准种变异特征

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中华微生物学和免疫学杂志 2024年第5期44卷 406-413页

作者：代漫李佳李茜瑶刘安孙丽君李洁吕诗韵黄辉煌卢红艳黄春辛若雷宜宾市第三人民医院医务科宜宾644000 北京市疾病预防控制中心性病艾滋病防治所北京100013 首都医科大学附属北京佑安医院感染中心门诊北京100069 解放军总医院第五医学中心感染病医学部爱心门诊北京100039

目的运用单基因组扩增法(single genome amplification,SGA)分析北京报告的HIV-1 CRF103_01B感染者体内3′半长基因组准种变异特征。方法选择2017—2020年北京新诊断或初始抗病毒治疗病例耐药监测中发现的6例CRF103_01B感染者,提取血浆... 详细信息

目的运用单基因组扩增法(single genome amplification,SGA)分析北京报告的HIV-1 CRF103_01B感染者体内3′半长基因组准种变异特征。方法选择2017—2020年北京新诊断或初始抗病毒治疗病例耐药监测中发现的6例CRF103_01B感染者,提取血浆RNA。采用系列倍比稀释法稀释3′端cDNA,巢式PCR扩增CRF103_01B准种病毒3′半长基因组序列。MEGA 11构建Neighbor-Joining(NJ)系统进化树,计算准种病毒基因距离,Highlighter工具可视化准种病毒遗传变异。利用Simplot 3.5软件对准种序列进行BootScan分析,以分析病毒准种间重组。经Geno2pheno在线工具预测病毒嗜性。结果6例CRF103_01B感染者中有5例经男男性行为感染,共获得144条3′半长基因组SGA序列(19~36条/例)。NJ进化树显示6例感染者3′半长基因组准种变异复杂程度不一。急性期HIV-1感染病例BL4748-00准种病毒变异较小,组内基因距离为0.002±0.000,表现出遗传同质性。BL4981-00、BL3150-00和BL3558-00病例准种病毒分别形成至少3个次级进化簇呈现不同的进化方向,其组内基因距离0.031±0.004≥BL3150-00>BL3558-00>BL4981-00≥0.016±0.002。夫妻BL3022-00(女)和BL3023-00准种病毒序列聚集成大单系进化簇(bootstrap值为100%),后者组内基因距离(0.025±0.003)高于前者(0.019±0.002)。BL3558-00病例存在准种病毒间重组现象。6例感染者的准种病毒均为CCR5嗜性。结论CRF103_01B感染者体内准种变异复杂程度与疾病进展有关,急性期病例表现遗传同质性,慢性期感染病例呈现多个进化方向。未发现共感染或超感染现象,但是部分病例存在准种间重组事件。

关键词： HIV CRF103_01B 单基因组扩增准种变异男男性行为

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西昆仑晚古生代盆地演化与成矿作用

矿物学报 2024年第4期44卷 478-492页

作者：张羽佳李溪遥吴承泉徐进鸿张正伟中国科学院地球化学研究所矿床地球化学国家重点实验室贵州贵阳550081 河南省地质研究院河南郑州450016 贵州省铜仁学院贵州铜仁554300

在西昆仑北部地区,由于古特提斯洋汇聚作用,导致形成弧后伸展构造带以及一系列晚古生代沉积盆地。本文着重综述以下几个问题:1)位于塔里木地块南缘上的塔木-卡兰古盆地带,由于坳陷作用连续沉积了中泥盆统-上二叠统地层,其构造位置相当... 详细信息

在西昆仑北部地区,由于古特提斯洋汇聚作用,导致形成弧后伸展构造带以及一系列晚古生代沉积盆地。本文着重综述以下几个问题:1)位于塔里木地块南缘上的塔木-卡兰古盆地带,由于坳陷作用连续沉积了中泥盆统-上二叠统地层,其构造位置相当于远域大陆弧后环境盆地;位于西昆仑地块北缘的奥依塔格-库尔良弧后盆地带,由于裂陷作用断续地沉积了中泥盆统-上二叠统地层,其构造位置相当于弧后盆地。虽然这两个盆地带之间被铁克里克断隆带所分隔,但它们的演化过程具有同时性。2)盆地中主要有两期岩浆岩活动,一是与盆地扩张期同生的“双峰式”岩浆岩(339~291 Ma),二是与盆地闭合有关的中酸性岩浆岩(265~206 Ma);3)在盆地演化过程中,中泥盆世-早二叠世是盆地扩张期,在局部坳陷的封闭盆地和缺氧环境下形成同生沉积矿床,主要包括海相砂岩型铜矿床、喷流沉积型铅锌矿床、沉积锰矿床以及VMS型铜矿床;中二叠世-早三叠世是盆地闭合期,由于盆-山转换作用导致沉积基底褶皱和岩浆活动,并形成了构造-热液和岩浆热液成矿作用。总之,晚古生代区域伸展构造环境受制于古特提斯汇聚作用,在这些盆地扩张到闭合的演化过程中,形成沉积型矿床、岩浆热液型矿床和构造-热液型矿床。

关键词：晚古生代盆地弧后伸展环境铅-锌-铜-锰矿床西昆仑

北京两株HIV-1独特重组型CRF5501B/CRF07BC近全长基因组遗传特征分析

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国际病毒学杂志 2024年第4期31卷 280-284页

作者：肖明凤李佳李茜瑶刘安孙丽君卢红艳辛若雷中国医科大学公共卫生学院沈阳110122 北京市疾病预防控制中心性病艾滋病防治所 100013 首都医科大学附属北京佑安医院感染中心门诊 100069

目的对北京治疗前耐药监测发现的具有遗传相似性的两株新发重组毒株进行前病毒HIV-1 DNA近全长基因组扩增和序列分析,以了解其遗传特征和重组模式。方法对北京佑安医院募集的2例新发重组毒株感染者,用广州海力特公司核酸提取和纯化试剂... 详细信息

目的对北京治疗前耐药监测发现的具有遗传相似性的两株新发重组毒株进行前病毒HIV-1 DNA近全长基因组扩增和序列分析,以了解其遗传特征和重组模式。方法对北京佑安医院募集的2例新发重组毒株感染者,用广州海力特公司核酸提取和纯化试剂从白细胞富集层提取前病毒HIV-1 DNA。运用SimPlot 3.5软件分析重组模式和断点,并用Mega 11构建分片段最大似然法进化树验证重组事件。结果从2个男男性行为(men who have sex with men,MSM)感染者扩增获得HIV-1近全长基因组序列。SimPlot重组断点分析显示BL6218-00和BL6017-01基因组均以CRF5501B为骨架,分别在gag和env基因区,或gag、pol、vpu/env、nef/3’LTR基因区,由CRF07BC重组而成。2条序列的CRF07BC片段均与来自MSM人群的CRF07BCN参考毒株序列聚集成单系进化簇。结论用前病毒DNA扩增方法从北京MSM人群发现了两株以CRF5501B为骨架且重组模式不同的独特重组型毒株,重组亲本CRF07BC均来自我国北方MSM人群。

关键词：独特重组型近全长基因组前病毒DNA 系统进化