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Genetic Variation of Inbred lines of Maize Detected by SSR Markers

Agricultural Sciences in China 2001年第1期 14-20页

作者： li xin-hai fu jun-hua zhang shi-huang yuan li-xing li ming-shun The Institute of Crop Breeding and Cultivation Chinese Academy of Agoriculturas Sciences Key Laboratory of Crop Breeding and Cultivation Ministry of Agriculture Beijing 100081 The Institute of Crop Breeding and Cultivation Chinese Academy of Agoriculturas Sciences Key Laboratory of Crop Breeding and Cultivation Ministry of Agriculture Beijing 100081 The Institute of Crop Breeding and Cultivation Chinese Academy of Agoriculturas Sciences Key Laboratory of Crop Breeding and Cultivation Ministry of Agriculture Beijing 100081 The Institute of Crop Breeding and Cultivation Chinese Academy of Agoriculturas Sciences Key Laboratory of Crop Breeding and Cultivation Ministry of Agriculture Beijing 100081 The Institute of Crop Breeding and Cultivation Chinese Academy of Agoriculturas Sciences Key Laboratory of Crop Breeding and Cultivation Ministry of Agriculture Beijing 100081

Simple sequence repeats (SSRs) were used to detect genetic variation among 21 maize(Zea mays L. ) inbred lines. Forty-three SSR primers selected from 69 primers gave stable amplification profiles, which could be clearly resolved on 3% Metaphor agarose gel, and produced 127 polymorphic amplified *** average number of alleles per SSR locus was 2.95 with a range from 2 to 7. The polymorphism information content (PIC) for the SSR loci varied from 0.172 to 0.753 with an average of 0.511. Genetic similarities among the 21 lines ranged from 0.480 between the combination of Zhongzi451 vs. K12 up to 0.768 between CA156 vs. Ye478. The cluster analysis showed that 21 inbred lines could be classified into two distinct clusters with several subclusters, which corresponded to the heterotic groups determined by their pedigree *** SSR primers, which had high level of polymorphism, could allow a rapid and efficient identification of 21 inbreds. Consequently, SSR markers could be used for measuring genetic variation of maize inbred lines and assigning them to heterotic groups.

关键词： Maize Simple sequence repeats Genetic variation Heterotic groups Polymorphism information content

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A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group

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World Journal of Pediatrics 2024年第6期20卷 590-601页

作者： Meng-Jie Tang Xiao-li Ma Xiang-ling He Wei-hua Pan Xiao-Hong zhang Sha-Yi Jiang Ju Gao fu li Wei Yao Song Gu Wei-ling zhang Qiang Zhao shi-Hao huang Yong-jun Fang Wei liu Hui-Zhong Niu Chun-Mei Wang li-Rong Sun Hui Gao Yun-Peng Dai shun-Gen huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong li liang-Chun Yang Ye-ming Wu huan-Min Wang xin Sun Xiao-jun yuan Department of Pediatric Hematology/Oncology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNo.1665Kongjiang RoadYangpu DistrictShanghai 200092China Medical Oncology Department Pediatric Oncology CenterBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Hematology/Oncology Children's Medical CenterHunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 41005China Department of Pediatric Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Hematology/Oncology Guangzhou Women and Children's Medical CenterNational Children's Medical Center for South Central RegionGuangzhou 510623China Department of Hematology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610041China Department of Hematology/Oncology Qilu Children's Hospital of Shandong UniversityJinan 250022China Department of Pediatric Surgery Children's Hospital of Fudan UniversityShanghai 201102China Department of General Surgery Shanghai Children's Medical Center(National Children's Medical Center-Shanghai)Shanghai Jiao Tong University School of MedicineShanghai 200127China Department of Pediatrics Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Pediatric Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Hematology/Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210008China Department of Hematology/Oncology Henan Children's HospitalZhengzhou 450018China Department of Pediatric General Surgery Hebei Children's Hospital of Hebei Medical UniversityShijiazhuang City 050031China Children's Hospital the First Affliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Paediatric

Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)in *** A multicenter,prospective study that included 399 patients with HB from January 2015 to june 2020 was *** demographics,treatment protocols,and other related information were *** regression models and Kaplan-Meier curve methods were *** The 4-year event-free survival(EFS)and overall survival(OS)were 76.9 and 93.5%,*** 4-year EFS rates for the very-low-risk,low-risk,intermediate-risk,and high-risk groups were 100%,91.6%,81.7%,and 51.0%,*** 4-year 0S was 100%,97.3%,94.4%,and 86.8%,*** regression analysis found that age,tumor rupture(R+),and extrahepatic tumor extension(E+)were independent prognostic factors.A total of 299 patients had complete remission,and 19 *** with declining alpha-fetoprotein(AFP)>75%after the first two cycles of neoadjuvant chemotherapy had a better EFS and OS than those≤75%.Conclusions The survival outcome of HB children has dramatically improved since the implementation of CCCG-HB-2016 ***≥8 years,R+,and E+were independent risk factors for *** with a declining AFP>75%after the first two cycles of neoadjuvant chemotherapy had better EFS and OS.

关键词： Alpha-fetoprotein Hepatoblastoma Multicenter Prospective study Survival

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Safety profile of 0.0015%tafluprost eye drops in China:a post-marketing observational study

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International Journal of Ophthalmology(English edition) 2023年第1期16卷 108-114页

作者： Xue-li Chen Yan-Jing fu Bo Qu Ye-Wei Wang xin Tang Yu-Hong Wang Guo-Yi Zhou ming-Kai lin Jing-yuan Shen Jin Yao Su-Yan li Miao-Qin Wu hua-Zong Peng ming-Ying Lai Ren-Yi Wu Yi-Nong zhang Yan li Xiao-jun Wu ming-Chang zhang Su-Ping Guo xing-huai Sun Department of Ophthalmology Eye&ENT Hospital of Fudan UniversityShanghai 200000China Department of Ophthalmology Daqing Ophthalmologic HospitalDaqing 163000Heilongjiang ProvinceChina Department of Ophthalmology the Fourth Affiliated Hospital of China Medical UniversityShenyang 110000Liaoning ProvinceChina Department of Ophthalmology Da Lian He Eye Specialist HospitalDalian 116000Liaoning ProvinceChina Department of Ophthalmology Beijing Tongren HospitalBeijing 100000China Department of Ophthalmology Xiamen Eye Center of Xiamen UniversityXiamen 361000Fujian ProvinceChina Department of Ophthalmology Yueqing People’s HospitalWenzhou 325600Zhejiang ProvinceChina Department of Glaucoma Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510000Guangdong ProvinceChina Department of Ophthalmology Shengzhou Shen’s Eye HospitalShaoxing 312400Zhejiang ProvinceChina Department of Ophthalmology the Affiliated Eye Hospital of Nanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina Department of Ophthalmology Xuzhou No.1 Peoples HospitalXuzhou 221000Jiangsu ProvinceChina Department of Ophthalmology Zhejiang Provincial People’s HospitalHangzhou 310000Zhejiang ProvinceChina Department of Ophthalmology Wuhan Eyegood Ophthalmic HospitalWuhan 430014Hubei ProvinceChina Department of Ophthalmology Shenzhen Eye HospitalShenzhen 518001Guangdong ProvinceChina Department of Glaucoma Shanghai Heping Eye HospitalShanghai 200000China Department of Ophthalmology Wuxi Second People’s HospitalWuxi 214000Jiangsu ProvinceChina Department of Ophthalmology First Affiliated Hospital of Kunming Medical UniversityKunming 650000Yunnan ProvinceChina Department of Ophthalmology Union Shenzhen Hospital(Nanshan Hospital)Shenzhen 518000Guangdong ProvinceChina Department of Ophthalmology Wuhan Union HospitalWuhan 430000Hubei ProvinceChina Department of Ophthalmology Shengyang He Eye Specialist HospitalShenyang 110000Liaoning ProvinceChina

AIM:To investigate the treatment pattern and safety of tafluprost for glaucoma and ocular hypertension(OH)in clinical practice in ***:This post-marketing observational study included patients who received tafluprost to lower intraocular pressure(IOP)within 30d between September 2017 and March 2020 in 20 hospitals in *** drug reactions(ADRs)during tafluprost treatment and within 30d after the treatment were ***:A total of 2544 patients were included in this study,of them 58.5%(1488/2544)had primary open angle glaucoma(POAG),21.9%(556/2544)had OH and 19.7%(500/2544)used tafluprost for other *** 359 ADRs occurred in 10.1%(258/2544)patients,and no serious adverse event *** most common ADR was conjunctival hyperemia(128 ADRs in 124 patients,4.9%).Totally 1670 participants(65.6%)combined tafluprost with carbonic anhydrase inhibitors(CAIs;37.1%,620/1670),sympathomimetics(33.5%,559/1670),β-blockers(33.2%,555/1670),other prostaglandin analogs(PGAs;15.6%,260/1670)and other eye drops(15.1%,253/1670).The highest incidence of conjunctival hyperemia was noted in patients who received tafluprost in combination with other PGAs(23 ADRs in 23 patients,8.8%,23/260)and the lowest was in combination with CAIs(16 ADRs in 16 patients,2.6%,16/620).Tafluprost was applied in primary angle-closure glaucoma(41.6%,208/500),after glaucoma surgery(17.8%,89/500)and after non-glaucoma surgery(15.8%,79/500).CONCLUSION:Tafluprost is safe for POAG and OH,and tolerable when combined with other eye drops and under various clinical circumstances.

关键词： tafluprost glaucoma ocular hypertension intraocular pressure adverse drug reactions

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The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-lin Xiong Xiang-Yang Wen xin-Qiao li Ce Cai Shuo Xiao Qi Luo Wen-Xi Peng Dong-Ya Guo Zheng-hua An Ke Gong Jin-yuan liao Yan-Qiu zhang Yue huang Lu li xing Wen Fei zhang Jing Duan Chen-Wei Wang Dong-li shi Peng zhang Qi-Bin Yi Chao-Yang li Yan-Bing Xu Xiao-hua liang Ya-Qing liu Da-li zhang Xi-Lei Sun Fan zhang Gang Chen huan-Yu Wang Sheng Yang Xiao-Jing liu Min Gao Mao-shun li Jin-Zhou Wang xing Zhou Yi Zhao Wang-Chen Xue Chao Zheng Jia-Cong liu xing-Bo Han Jin-ling Qi Jia huang Ke-Ke zhang Can Chen Xiong-Tao Yang Dong-Jie Hou Yu-Sa Wang Rui Qiao Xiang Ma Xiao-Bo li Ping Wang xin-Ying Song li-ming Song shi-Jie Zheng Bing li Hong-Mei zhang Yue Zhu Wei Chen Jian-Jian He Zhen zhang Jin Hou Hong-jun Wang Yan-Chao Hao Xiang-Yu Wang Zong-yuan Yang Zhi-Long Wen Zhi Chang yuan-yuan Du Rui Gao Xiao-Fei Lan Yan-Guo li Gang li Xu-Fang li Fang-jun Lu Hong Lu Bin Meng Feng shi Hui Wang Hui-Zhen Wang Yu-Peng Xu Jia-Wei Yang Xue-Juan Yang Shuang-Nan zhang Chao-Yue zhang Cheng-Mo zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li Luo Yong-Heng Zhao Gang Zhao li-Cai Deng Xiao-Wei liu Yi-Peng Jing Gang Wang Hao-Tong zhang Jian-Rong shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping li Zhong-Rui Bai Yue Wu Yan Cai Shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin hai-yuan Chen Jian-jun Chen Kun-xin Chen li Chen Xue-Lei Chen Xiao-Yan Chen Ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-xin Guo Zhan-Wen Han Bo-liang He Jin-liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei Jia Fang-hua Jiang Xiang Jiang Zhi-Bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua li Chang-hua li Guang-Wei li hai-Ning li Jian li Qi li Shuang li Sha-Sha li xin-Nan li Yan li Yin-Bi li Ye-Ping li yuan liang Chien-Cheng lin Chao liu Gen-Rong liu Guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-jun Ni Zhao-Xiang Qi Yong-jun Qi shi-Yin Shen Huo-ming shi Jing Song Yi-Han Song Ding-Qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng Tao yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-ling Wang Jian-Ping Wang jun-Xian Wang Lei Wang Meng-xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng Wei ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-Zheng xing ling-Zhe Xu xin-Qi Xu Yan Xu Tai-Sheng Yan De-hua Yang hai-Feng Yang Hui-Qin Yang ming Yang Zheng-Qiu Yao Yong Yu Hui yuan hai-Bo yuan hai-Long yuan Wei-Min yuan Chao Zhai En-Peng zhang hua-Wei zhang Jian-Nan zhang li-Pin zhang Wei zhang Yong zhang Yan-Xia zhang Zheng-Chao zhang ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

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Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)

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Military Medical Research 2020年第3期7卷 249-282页

作者： Ying-Hui Jin Qing-yuan Zhan Zhi-Yong Peng Xue-Qun Ren Xun-Tao Yin lin Cai Yu-Feng yuan Ji-Rong Yue Xiao-Chun zhang Qi-Wen Yang Jianguang Ji Jian Xia Yi-Rong li fu-Xiang Zhou Ya-Dong Gao Zhui Yu Feng Xu ming-li Tu li-ming Tan Min Yang Fang Chen Xiao-Ju zhang Mei Zeng Yu Zhu xin-Can liu Jian Yang Dong-Chi Zhao Yu-Feng Ding Ning Hou fu-Bing Wang Hao Chen Yong-Gang zhang Wei li Wen Chen Yue-Xian shi Xiu-Zhi Yang Xue-jun Wang Yan-jun Zhong ming-Juan Zhao Bing-Hui li lin-Lu Ma Hao Zi Na Wang Yun-Yun Wang Shao-fu Yu Lu-Yao li Qiao huang Hong Weng Xiang-Ying Ren li-Sha Luo Man-Ru Fan Di huang Hong-Yang Xue lin-xin Yu Jin-Ping Gao Tong Deng Xian-Tao Zeng Hong-jun li Zhen-shun Cheng Xiao-Mei Yao xing-huan Wang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Respiratory Diseases China-Japan Friendship HospitalBeijing 100029China Department of Pulmonary and Critical Care Medicine China-Japan Friendship HospitalBeijing 10029China Leishenshan Hospital in Wuhan Wuhan 430200China Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institutes of Evidence-based Medicine and Knowledge Translation Henan UniversityKaifeng 475000HenanChina Department of Medical Imaging Guizhou Provincial People’s HospitalGuiyang 550002China Departments of Orthopedics Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Clinical Laboratory Peking Union Medical College Hospital(PUMCH)Peking Union Medical CollegeChinese Academy of Medical Sciences(CAMS)Beijing 100730China Center for Primary Health Care Research Lund University and Region Skåne25002 MalmöSweden Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 403371China Department of Allergology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan 43071China Department of Critical Care Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Emergency Medicine and Chest Pain Center Qilu Hospital of Shandong UniversityJinan 250002China Department of Respiratory and Critical Care Medicine Suizhou Central HospitalHubei University of MedicineSuizhou 441300HubeiChina Department of Clinic Pharmacy Second People’s Hospital of Huaihua Ci

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the *** and treatment guidelines for clinicians caring for patients are *** the early stage,we have issued"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)";now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based *** formed a working group of clinical experts and *** steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge *** searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)*** were either strong or weak,or in the form of ungraded consensus-based ***,we issued 34 *** them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based *** covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung

关键词： COVID-19 SARS-CoV-2 Recommendation Chemoprophylaxis Diagnosis Treatment Discharge management Traditional Chinese medicine guideline

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Advances in nuclear detection and readout techniques

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Nuclear Science and Techniques 2023年第12期34卷 281-358页

作者： Rui He Xiao‑Yang Niu Yi Wang Hong‑Wei liang Hong‑Bang liu Ye Tian Hong‑lin zhang Chao‑Jie Zou Zhi‑Yi liu Yun‑Long zhang hai‑Bo Yang Ju huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai li‑Min Duan Rui‑Rui Fan Fang‑Fa fu Jian‑hua Guo Dong Han Wei Jiang Xian‑Qin li xin li Zhuo‑Dai li Yu‑Tie liang shun liao De‑Xu lin Cheng‑ming liu Guo‑Rui liu jun‑Tao liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran Xiang‑ming Sun Bo‑Tan Wang Jia Wang Jin‑Xiang Wang Qi‑lin Wang Yong‑Sheng Wang Xiao‑Chuan Xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong yuan Chun‑Hui zhang Rui‑Guang Zhao Ran Zheng Cheng‑xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000China Key Laboratory of Particle and Radiation Imaging Department of Engineering PhysicsTsinghua UniversityBeijing 100084China School of Integrated Circuits Dalian University of TechnologyDalian 116020China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Electronic Engineering School Heilongjiang UniversityHarbin 150080China Spallation Neutron Source Science Center Dongguan 523803China Micro‑electronic Department Harbin Institute of TechnologyHarbin 150001China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210034China liaoning Academy of Materials Shenyang 110167China Istituto Nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly School of Mathematics and Physics Chengdu University of TechnologyChengdu 620035China PLAC Key Laboratory of Quark and Lepton Physics(MOE)Central China Normal UniversityWuhan 430079China School of Electronics and Information Northwestern Polytechnical UniversityXi’an 710129China State Key Lab of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China School of Computer Science Northwestern Polytechnical UniversityXi’an 710129China

“A Craftsman Must Sharpen His Tools to Do His Job,”said *** detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the ***,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,*** article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout *** explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community.

关键词： Silicon detector Wide bandgap detector Time projection chamber(TPC) Multigap resistive plate chamber detector(MRPC) Scintillation detector Calorimeters Cherenkov detector Transition radiation detector Artificial intelligence Trigger-less readout

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-xin liu Yue huang Guang-Cheng Xiao Qing-Cui Bu Jin-Lu Qu Shu zhang Shuang-Nan zhang Shu-Mei Jia Fang-jun Lu Xiang Ma lian Tao Wei zhang li Chen li-ming Song Ti-Pei li Yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen Yu-Peng Chen Wei Cui Wei-Wei Cui Jing-Kang Deng Yong-Wei Dong yuan-yuan Du Min-Xue fu Guan-hua Gao He Gao Min Gao ming-Yu Ge Yu-Dong Gu Ju Guan Cheng-Cheng Guo Da-Wei Han Jia Huo Lu-hua Jiang Wei-Chun Jiang Jing Jin Yong-Jie Jin ling-Da Kong Bing li Cheng-Kui li Gang li Mao-shun li Wei li Xian li Xiao-Bo li Xu-Fang li Yang-Guo li Zheng-Wei li Xiao-hua liang Jing-yuan liao Bai-Sheng liu Guo-Qing liu Hong-Wei liu Xiao-Jing liu Yi-Nong liu Bo Lu Xue-Feng Lu Qi Luo Tao Luo Bin Meng Yi Nang Jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang xin-Ying Song liang Sun Ying Tan You-li Tuo Chen Wang Guo-Feng Wang Juan Wang ling-jun Wang Weng-Shuai Wang Yu-Sa Wang Xiang-Yang Wen Bai-Yang Wu Bo-Bing Wu Mei Wu Shuo Xiao Shao-lin Xiong He Xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-jung Yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-Mei zhang Cheng-Mo zhang Fan zhang Hong-Mei zhang Juan zhang Tong zhang Wan-Chang zhang Wen-Zhao zhang Yi zhang Yi-Fei zhang Yong-Jie zhang yuan-Hang zhang Yue zhang Zhao zhang Zhi zhang Zi-liang zhang hai-Sheng Zhao Xiao-Fan Zhao shi-Jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-Feng Zhou Yu-Xuan Zhu Ren-lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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Searching for ^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： Bing-Tao zhang jun-Zheng Wang li-Tao Yang Qian Yue Ke-jun Kang yuan-Jing li hai-Peng An C.Greeshma Jian-Ping Chang Yun-huan Chen Jian-Ping Cheng Wen-Han Dai Zhi Deng Chang-Hao Fang xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-yuan Guo li He Sheng-ming He Jin-Wei Hu Han-Xiong huang Tu-Chen huang hai-Tao Jia Xi Jiang S.Karmakar Hao-Bin li Jian-Min li Jin li Qian-Yun li Ren-ming-Jie li Xue-Qian li Yu-Lan li Yi-Fan liang Bin liao Fong-Kay lin shin-Ted lin Jia-Xuan liu Shu-Kui liu Yan-Dong liu Yu liu yuan-yuan liu Zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-yuan Nie Jin-hua Ning Hui Pan Ning-Chun Qi Jie Ren Xi-Chao Ruan Ze She Manoj Kumar Singh Tian-Xi Sun Chang-Jian Tang Wei-You Tang Yang Tian Guang-fu Wang li Wang Qing Wang Yu-Feng Wang Yun-Xiang Wang Henry-Tsz-King Wong shi-Yong Wu Yu-Cheng Wu Hao-Yang xing Rui Xu Yin Xu Tao Xue Yu-Lu Yan Nan Yi Chun-Xu Yu hai-jun Yu Jian-Feng Yue ming Zeng Zhi Zeng Feng-Shou zhang Lei zhang Zhen-hua zhang Zhen-Yu zhang Kang-Kang Zhao ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou Jing-jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 YaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of ^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<3.2–7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

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Anatomical characteristics of patients with symptomatic severe aortic stenosis in China

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Chinese Medical Journal 2021年第22期134卷 2738-2740页

作者： Tian-yuan Xiong Yi-ming li Yi-jun Yao Yu-Heng Jia Kai Xu Zhen-Fei Fang jun Jin Guo-Sheng fu Yi-Ning Yang Lei Jiang Wei-Dong li Yan-Qing Wu Yan-Song Guo Ran Guo Yun-Dai Chen Yi li Yi-Bing Shao Yi zhang Bo-Sen Yang Yi-Ke zhang Jing-Jing He Kai-Yu Jia Sheng-Hu He Fa-xin Ren Jian-Cheng Xiu xing-hua Gu liang-Long Chen Ke Han yuan Feng Mao Chen Department of Cardiology West China HospitalSichuan UniversityChengduSichuan 610041China State Key Lab of Hydraulics and Mountain River Engineering Sichuan UniversityChengduSichuan 610044China Department of Cardiology General Hospital of Northern Theater CommandShenyangLiaoning 110015China Department of Cardiology The Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China Department of Cardiology Xinqiao Hospital of Third Military Medical UniversityChongqing 400037China Department of Cardiology Sir Run Run Shaw Hospital of Zhejiang UniversityHangzhouZhejiang 310016China Department of Cardiology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiang 830011China Department of Cardiology The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China Department of Cardiovascular Surgery The First Affiliated Hospital of Zhejiang UniversityHangzhouZhejiang 310009China Department of Cardiology The Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi 330006China Department of Cardiology Fujian Provincial HospitalFuzhouFujian 350013China Department of Cardiology The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning 116011China Department of Cardiology Chinese People’s Liberation Army General Hospital(301 Hospital)Beijing 100853China Department of Cardiology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Cardiology Qingdao Municipal HospitalQingdaoShandong 266071China Department of Cardiology Subei People’s HospitalYangzhouJiangsu 225001China Department of Cardiology Yantai Yuhuangding HospitalYantaiShandong 264000China Department of Cardiology Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdong 510515China Department of Cardiovascular Surgery Qilu Hospital of Shandong UniversityJinanShandong 250063China Department of Cardiology Fujian Medical University Union HospitalFuzhouFujian 350001China Department of Cardiology

With accumulating evidence of transcatheter aortic valve replacement(TAVR)worldwide,it is gradually realized that patients being treated are different across different coun-tries,including but not limited to their age,habitus,disease etiology,aortic valve morphology,and sizes of structures.[1]In China,the average age of TAVR patients is around 5 years younger than industrialized countries,[2]making Chinese patients a good predictive sample of what the industrialized countries might see in TAVR screening in the near future due to the expansion of this technique to younger patients,but anatomical features appreciated from multi-slice computed tomography(MSCT)in the Chinese patient population have not been well demonstrated.

关键词： patients aortic younger

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