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Fracture behavior of sandstone with partial filling flaw under mixed-mode loading: Three-point bending tests and discrete element method

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第1期17卷 291-308页

作者： Dongdong Ma Yu Wu xiao Ma Xunjian Hu Wenbao Dong Decheng li lingyu li State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou221116China State Key Laboratory of Structural Health and Safety of Bridges Wuhan430034China Research Center of Coastal and Urban Geotechnical Engineering Zhejiang UniversityHangzhou310058China State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China

The fracture behavior of natural fracture in the geological reservoir subjected to filling property,affects the crack initiation and propagation under stress *** filling flaws were intermediate between open fractures and filled fractures,the fracture response may be worth *** this work,the effect of the filling property of sandstone with partial filling flaws on the fracture behavior was systematically investigated based on three-point bending tests and the numerical approach of discrete element method(DEM).In the laboratory,semi-circular three-point bending tests were carried out with partial filling flaws of various filling *** on this,numerical simulations were used to further investigate the effect of the filling ratio and the inclination of the partial filling flaw on the mechanical and fracture responses,and the effect of the partial filling flaw under mixed-mode loading on the fracture mechanism was elucidated coupled with acoustic emission(AE)*** obtained results showed that the increase in filling strength and filling ratio of partial filling flaw led to an increase in peak strength,with a decreasing trend in peak strength with the inclination of partial filling *** terms of crack propagation pattern,the increasing filling strength of the partial filling flaw induced the transformation of the fracture mechanism toward deflection,with a tortuosity path,while the filling ratio and inclination of partial filling flaw led to fracture mechanism change from deflection to penetration and attraction,accompanied with a larger AE event source in ***,the b-value based on the Gutenberg-Richter equation fluctuated between 5 and 4 at low filling ratio and inclination and remained around 5 at high filling ratio and inclination of partial filling *** results may provide an application prospective for reservoir stimulation using the natural fracture system.

关键词： Partial filling flaw Mixed-mode loading Semi-circular three-point bending Acoustic emission(AE) b-value

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不同超声能量模式在硬核白内障超声乳化吸除术中的应用观察

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中国实用眼科杂志 2008年第1期26卷 41-43页

作者：滕贺李筱荣天津医科大学眼科中心天津300070

目的探讨连续、脉冲、爆破3种超声能量模式在硬核白内障超声乳化吸除术中应用。方法选取晶状体核硬度〉Ⅲ级（LOCSⅡ分级标准）的老年性白内障患者185例（212只眼），随机分为3组，分别采用连续、脉冲、爆破3种超声能量模式行超声乳... 详细信息

目的探讨连续、脉冲、爆破3种超声能量模式在硬核白内障超声乳化吸除术中应用。方法选取晶状体核硬度〉Ⅲ级（LOCSⅡ分级标准）的老年性白内障患者185例（212只眼），随机分为3组，分别采用连续、脉冲、爆破3种超声能量模式行超声乳化白内障吸出联合后房型人工晶状体植入术，观察术中实际超声过程中平衡液的用量、超声乳化晶状体核的实际超声能量（actual power，AP）、有效超声时间（effect phaco time，EPT），和累积能量复合参数（accumulated energy complex parameter，AECP），比较术后角膜内皮细胞丢失率及角膜切口热灼伤状况。结果爆破组实际超声过程中平衡液的用量远远低于脉冲及连续组，差异显著有统计学意义（P〈0．05）。爆破组AP与脉冲组相比无统计学意义（P＞0．05），EPT、AECP明显低于脉冲组（P〈0．05）。AP、EPT、AECP均明显低于连续组（P〈0．05）。术后l周爆破组角膜内皮细胞密度高于脉冲及连续组，角膜内皮细胞丢失率明显低于脉冲及连续组，差异有统计学意义（P〈0．05）。全部3组病人术后均无角膜切口热灼伤。结论爆破模式在处理硬核白内障时可显著减少实际超声中平衡液的使用量，降低术中EPT和累计超声能量，从而减轻对眼内组织的损伤，提高了手术效率，是一种更为优化利用能量的模式。

关键词：超声乳化白内障吸出术超声能量模式爆破模式硬核白内障

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Decellularized amniotic membrane promotes the anti-inflammatory response of macrophages via PI3K/AKT/HIF-1α pathway

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Chinese Chemical Letters 2025年第1期36卷 403-407页

作者： Xiongbo Song Jinwen xiao Juan Wu li Sun Long Chen Department of Orthopedics Guizhou Provincial People’s HospitalGuiyang 550000China The Lab of Tissue Engineering and Translational Medicine College of MedicineGuizhou UniversityGuiyang 550000China Wuhan Kangchuang Biotechnology Wuhan 430074China

Macrophages undergo dynamic transitions between M1 and M2 states,exerting profound influences on both inflammatory and regenerative *** biocompatible and wound-healing properties of decellularized amniotic membrane(d AM)make it a subject of exploration for its potential impact on the anti-inflammatory response of *** findings unequivocally demonstrate that d AM promotes anti-inflammatory M2 polarization of macrophage,with its cytokine-rich content posited as a potential *** application of RNA sequencing unveils differential gene expression,implicating the hypoxia inducible factor-1α(HIF-1α)signaling pathway in this intricate *** investigation further demonstrates that d AM facilitates anti-inflammatory M2 polarization of macrophage through the upregulation of epidermal growth factor(EGF),which,in turn,activates the phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT)pathway and stabilizes HIF-1α.This cascade results in a noteworthy augmentation of anti-inflammatory gene *** study significantly contributes to advancing our comprehension of d AM's immunomodulatory role in tissue repair,thereby suggesting promising therapeutic potential.

关键词： Macrophage Decellularized amniotic membrane Anti-inflammatory response Hypoxia inducible factor-1α Epidermal growth factor

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Folding encapsulation toward lindqvist polyoxometalates within adaptive coordination cages for catalysis

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Science China Chemistry 2025年第2期68卷 561-569页

作者： Ying-Mei Zhong Jin-Jin Xuan Xujie Qin Han xiao Zi-Jun Xia li-Peng Zhou xiao-Qing Guo Yu-Hang Hu Lu Zhang Chunsen li li-Xuan Cai Qing-Fu Sun State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of Chinese Academy of Sciences Beijing 100049China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350007China

In nature,enzymes at specific folded conformations exhibit high substrate complementarity,enabling them to efficiently and selectively catalyze biochemical *** by enzymes,coordination cages with conformational dynamics have been designed and are receiving increasing attention due to their versatile applications in allosteric guest binding and *** present here two enzyme-mimicking adaptive macrocycle-based coordination cages,Pd_(2)L_(2)^(1) and Pd_(2)L_(2)^(2),from macrocycle-based ligands(L^(1) and L^(2))and the encapsulation and stabilization of lindqvist polyoxometalates anions M6O192−(M=W or Mo)in neutral aqueous solution.X-ray crystallographic studies have verified the formation of 1:1 host-guest complexes of two Pd_(2)L_(2) cages and the W6O192−anion,via an induced-fit folding *** with the free host,Pd_(2)L_(2)^(1) exhibited an induced-fit semi-folded conformation in the inclusion complex,while Pd_(2)L_(2)^(2) adopted an induced-fit fully-folded ***,the Mo_(6)O_(19)⊂Pd_(2)L_(2) host-guest complexes demonstrate high yield and selectivity in the oxidative decontamination reaction of the sulfur mustard simulant,2-chloroethyl ethyl *** work not only sheds light on the importance of conformational adaptability in enzyme-like systems but also paves the way for protecting labile POM clusters via host-guest encapsulation toward enhanced catalytic performance in aqueous solution.

关键词： coordination cage induced-fit polyoxometalates host-guest chemistry supramolecular catalysis

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Probing the special angle in twisted bilayer MoS_(2)via angle-dependent scanning tunneling microscopy studies

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Science China(Physics,Mechanics & Astronomy) 2025年第2期68卷 153-160页

作者： Xueying liu Shiying liu Yulong xiao Chang Xu Jiaxin Wu Kaihui li Si-Yu li Anlian Pan Key Laboratory for Micro-Nano Physics and Technology of Hunan Province Hunan Institute of Optoelectronic Integration and College of Materials Science and EngineeringHunan UniversityChangsha410082China School of Physics and Electronics Hunan Normal UniversityChangsha410081China

Twisted transition metal dichalcogenides(TMDs)homo-bilayers host unique quantum properties,which can be tuned by interlayer twist angleθ.However,the systematic evolution of their typical electronic properties with respect to the twist angleθ,which is crucial for identifying the“special angle”analogous to the“magic angle”of twisted bilayer graphene in correlation physics studies,remains incompletely ***,via scanning tunneling microscopy(STM)and spectroscopy(STS),we investigate the variation of the moirépotential,flat band,and layer polarization characteristics across a wide range of twist angleθin twisted bilayer MoS_(2)(TB-MoS_(2)).The moirépotential of the valence band exhibits a non-monotonic variation withθ,peaking at a maximum value up to 204 me Vatθ~1.7°.Concurrently,at the sameθ,the bandwidth of the flat band at theΓ_(V)point of the valence band attains its minimum,precisely signifying the“special angle”θ_(c)~1.7°in TB-MoS_(2).Interestingly,layer polarization in the moirésuperlattice is spatially visualized through the distribution of local density of states(LDOS)at the energies of bothΓ_(V)and K_(V)points of the valence band,where the polarization degree at theΓ_(V)point demonstrates a close dependency onθ.Our findings deepen understanding of twist-angle effect in TMDs,advancing both fundamental physics and practical application.

关键词： twisted bilayer MoS_(2) flat band moirépotential twist-angle dependence scanning tunneling microscopy

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资产重组、股价波动与内幕交易——来自中国A股市场重大资产重组的证据

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会计与经济研究 2013年第6期27卷 67-73页

作者：翟建强李小蓉财达证券有限责任公司河北石家庄050000 河北经贸大学会计学院河北石家庄050061

运用事件分析法构建了基于"窗口期"的内幕交易研究模型,以中国A股市场2008-2012年度重大资产重组事件为样本,研究了资产重组、股价波动和内幕交易的关系。研究发现,我国资本市场重大资产重组中显著存在内幕交易行为,加强关联交易和非国... 详细信息

运用事件分析法构建了基于"窗口期"的内幕交易研究模型,以中国A股市场2008-2012年度重大资产重组事件为样本,研究了资产重组、股价波动和内幕交易的关系。研究发现,我国资本市场重大资产重组中显著存在内幕交易行为,加强关联交易和非国有控股上市公司资产重组监管有助于遏制内幕信息散布,2008年加强重大资产重组信息管理的政策取得了明显效果。

关键词：资产重组股价波动内幕信息内幕交易

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Two-dimensional lateral magnetic tunnel junction with ultrahigh tunneling magnetoresistance

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Nano Research 2025年第2期18卷 958-964页

作者： Qiu-Qiu li Zhi-Fu Duan Wen-Wen liu rong Yang Bo li Ke-Qiu Chen Changsha Semiconductor Technology and Application Innovation Research Institute College of Semiconductors(College of Integrated Circuits)Hunan UniversityChangsha 410082China Department of Applied Physics School of Physics and ElectronicsHunan UniversityChangsha 410082China Research Institute of Hunan University in Chongqing Chongqing 401120China Shenzhen Research Institute of Hunan University Shenzhen 518063China

Giant tunneling magnetoresistance(TMR)has always been a pursuit in the research of magnetic tunnel junctions(MTJ).Two-dimensional(2D)magnetic materials have been used to construct lateral MTJ with high *** we investigated the crystal structure and magnetic property of CrSI monolayer,and found that it is a ferromagnetic semiconductor with a Curie temperature of about 180 *** CrSI monolayer with li adsorption(li-CrSI)show ferromagnetic half-metallic with a high Curie temperature of 300 *** we designed a lateral li CrSI/CrSI/li-CrSI monolayer *** TMR of the MTJs along b transport direction is 3 orders of magnitude times larger than that of the a transport direction,which should result from the different spin filtering ability along the two *** TMR of b transport direction in the MTJ is 7.67×10^(14),which is significantly higher than that of any reported lateral MTJs based on 2D *** results provide a promising avenue for designing lateral MTJs with giant TMR and high Curie temperature.

关键词： two-dimensional materials magnetic tunnel junctions CrSI monolayer tunneling magnetoresistance li atom adsorption

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Regulating crystallization and retarding oxidation in Sn-Pb perovskite via 1D cation engineering for high performance all-perovskite tandem solar cells

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Journal of Energy Chemistry 2025年第1期100卷 646-652页

作者： Ranran liu Xin Zheng Zaiwei Wang Miaomiao Zeng Chunxiang Lan Shaomin Yang Shangzhi li Awen Wang Min li Jing Guo Xuefei Weng Yaoguang rong Xiong li Michael Grätzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074HubeiChina Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055GuangdongChina School of Chemistry Chemical Engineering and Life SciencesState Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of Technology430070HubeiChina Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO) Chinese Academy of SciencesSuzhou 215123JiangsuChina School of Physics and Optoelectronic Engineering Hainan UniversityHaikou 570228HainanChina

All-perovskite tandem solar cells have the potential to surpass the theoretical efficiency limit of single junction solar cells by reducing thermalization ***,the challenges encompass the oxidation of Sn^(2+)to Sn^(4+)and uncontrolled crystallization kinetics in Sn-Pb perovskites,leading to nonradiative recombination and compositional heterogeneity to decrease photovoltaic efficiency and operational ***,we introduced an ionic liquid additive,1-ethyl-3-methylimidazolium iodide (EMIMI) into Sn-Pb perovskite precursor to form low-dimensional Sn-rich/pure-Sn perovskites at grain boundaries,which mitigates oxidation of Sn^(2+)to Sn^(4+)and regulates the film-forming dynamics of Sn/Pb-based perovskite *** optimized single-junction Sn-Pb perovskite devices incorporating EMIMI achieved a high efficiency of 22.87%.Furthermore,combined with wide-bandgap perovskite sub-cells in tandem device,we demonstrate 2-terminal all-perovskite tandem solar cells with a power conversion efficiency of 28.34%,achieving improved operational stability.

关键词： All-perovskite tandem solar cells Sn-Pb perovskite 1D Regulated crystallization Antioxidation

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投资者法律保护与财务报告质量

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特区经济 2008年第10期 253-254页

作者：王利娜李小蓉河北经贸大学河北石家庄050061

企业财务报告的质量取决于资本市场上会计信息需求方和供给方之间的博弈,投资者法律保护通过影响资本市场的发展,进而影响需求方和供给方之间的力量对比,使作为会计信息载体的财务报告呈现出不同的质量特征。

关键词：投资者法律保护财务报告质量稳健性

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan Yu xiao-li li xiao-Ting Sun li-Ting Wang Xia Wu ling-Jie Zhu xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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