检索结果-南通市图书馆

Phosphorylation of SiRAV1 at Ser31 regulates the SiCAT expression to enhance salt tolerance in Setaria italica

Journal of Integrative Agriculture 2023年第12期22卷 3638-3651页

作者： li qiao-lu li Zhi-yong WANG Meng-meng YAN Jing-wei FANG lin Guangdong Provincial Key Laboratory of Applied Botany/South China Botanical Garden Chinese Academy of SciencesGuangzhou 510650P.R.China Institute of Millet Crops Hebei Academy of Agriculture and Forestry SciencesShijiazhuang 050000P.R.China Nanjing Institute of Environmental Science Ministry of Ecology and EnvironmentNanjing 210042P.R.China State Key Laboratory of Subtropical Silviculture Zhejiang A&F UniversityHangzhou 311300P.R.China

Salinity severely affects plant growth and ***,it is crucial to identify the genes functioning in salt stress response and unravel the mechanism by which plants against salt *** study used the phosphoproteomic assay and found that 123 of the 4000 quantitative analyzed phosphopeptides were induced by salt *** functional annotation of the non-redundant protein database(NR)showed 23 differentially expressed transcription factors,including a phosphopeptide covering the Serine 31 in the RAV(related to ABI3/VP1)transcription factor(named SiRAV1).SiRAV1 was located in the *** and physiological analysis showed that overexpressing SiRAV1 in foxtail millet enhanced salt tolerance and alleviated the salt-induced increases of H_(2)O_(2) accumulation,malondialdehyde(MDA)content,and percent of electrolyte *** analysis showed that SiRAV1 positively regulated SiCAT expression to modulate the catalase(CAT)activity by directly binding to the SiCAT promoter in vivo and in ***,we found that phosphorylation of SiRAV1 at the Ser31 site positively regulated salt tolerance in foxtail millet via enhancing its binding ability to SiCAT promoter but did not affect its subcellular ***,our results define a mechanism for SiRAV1 function in salt response where salt-triggered phosphorylation of SiRAV1 at Ser31 enhances its binding ability to SiCAT promoter,and the increased SiCAT expression contributes to salt tolerance in foxtail millet.

关键词： foxtail millet salt stress phosphoproteomic SiRAV1 SiCAT

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Small World Effects in a Harmonious Unifying Hybrid Preferential Model Networks

引用

Communications in Theoretical Physics 2007年第2X期48卷 377-383页

作者： FANG Jin-Qing BI qiao li Yong lu Xin-Biao liU Qiang China Institute of Atomic Energy P.O. Box 275-81 Beijing 102413 China

Small worm effects in the harmonious unifying hybrid preferential model （HUHPM） networks are studied both numerically and analytically. The idea and method of the HUHPM is applied to three typical examples of unweighted BA model, weighted BBV model, and the TDE rnodel, so-called HUHPM-BA, HUHPM-BBV and HUHPM- TDE networks. Comparing the HUHPM with current typical models above, it is found that the HUHPM networks has the smallest average path length and the biggest average clustering coefficient. The results demonstrate that the HUHPM is more suitable not only for the un-iveighted models but also for the weighted models.

关键词： harmonious unifying hybrid preferential model small world effect network science

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phenotypic differentiation of neonatal rat cochlear spiral ganglion neurons following trypsin dissociation and culture

引用

Neural Regeneration Research 2008年第3期3卷 288-291页

作者： Dingjun Zha li qiao lianjun lu Xue Gao Tao Xue Wenjuan Mi Shunli liu Jianhua Qiu Department of Otolaryngology -Head and Neck Surgery Xijing Hospital Fourth Mifitary Medical University of Chinese PLA Xi＇an 710032Shaanxi Province China

BACKGROUND： Under laboratory conditions, cochlear spiral ganglion neurons are commonly isolated and cultured by mechanical dissociation. However, these neurons are extremely fragile and survive for only a short time. OBJECTIVE： To establish a trypsin dissociation and culture method for studying neonatal rat cochlear spiral ganglion neurons. DESIGN： A single sample study. SETTING： Department of Otolaryngology, Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University of Chinese PLA. MATERIALS： This study was performed at the central laboratory for Department of Otolaryngology, Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University of Chinese PLA from February to May 2006. A total of 40 neonatal Sprague Dawley rats of either gender, aged 2-5 days, were provided by the Laboratory Animal Center of the Fourth Military Medical University of Chinese PLA. Trypsin and neuronal-specific nuclear protein （NeuN） monoclonal antibodies were purchased from Sigma Company, USA. Culture medium was synthesized using Dulbecco＇s modified Eagle＇s medium （DMEM）/F12 （Gibco Company, USA） supplemented with 10% fetal bovine serum （Sigma Company, USA）, 100 000 U/L penicillin, and 1 mol/L NaOH. The following protocol was performed in accordance with ethical guidelines for the use and care of animals. METHODS： After anesthesia, rats were sacrificed by neck dislocation. A complete cochlear axis with spiral ganglion tissue was removed. The cochlear axis was rinsed three times in a culture dish with a diameter of 35 mm using Hank＇s balanced solution. After washings, the tissue was cut into pieces, digested with 0.25% trypsin for about 20 minutes, and incubated in a 37 ℃ water bath. The tissue was centrifuged, then mixed with serum-containing culture medium. Using a transfer pipette, the cell suspension was transferred to polylysine （0.1%）-treated culture dishes with a diameter of 35 mm. The culture dish was incubated at 37 ℃, with a 5% CO2-air environment. Once t

关键词： spiral ganglion neuron cell culture immunohistochemistry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Expression and subcellular localization of cysteine- and glycine-rich protein-2 in rat undifferentiated olfactory stem cells

引用

Neural Regeneration Research 2008年第5期3卷 558-560页

作者： Xue Gao Zengyu Cao Jun Chen Shunli liu Dingjun Zha Feng Wang Yang Chen li qiao lianjun lu Jianhua Qiu Department of Otorhinolaryngology Head and Neck Surgery Xijing Hospital the Fourth Mifitary Medical University Xi＇an 710032 ShaanxiProvince China

BACKGROUND： As a member of the liM protein family Ⅱ, cysteine- and glycine-rich protein-2 （CRP2） has been demonstrated to play a role in the regulation of growth and differentiation of eukaryotic cells. Our previous study has demonstrated that CRP2 can be detected in the embryonic rat inner ear but not in the adult rat inner ear. However, at present, the expression of liM protein family H members in stem or precursor cells has not been described. OBJECTIVE： To determine the expression and sub-cellular localization of CRP2 in olfactory stem cells. DESIGN, TIME AND SETTING： An experiment with repeated measures was performed in the Laboratory of Otorhinolaryngology, Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University from February 2008 to April 2008. MATERIALS： Olfactory stem cells, and rabbit-anti-CRP2 polyclonal antibody were prepared and kept in our laboratory. METHODS： Reverse transcription polymerase chain reaction and Western blot analysis were used to detect expression of CRP2 in olfactory stem cells. Immunocytochemistry was also used to localize CRP2 in olfactory stem cells. MAIN OUTCOME MEASURES： The expression and sub-cellular localization of CRP2 in rat olfactory stem cells. RESULTS： CRP2 expression was found in olfactory stem cells, and CRP2 was distributed in both the nucleus and the cytoplasm. CONCluSION： Confirmation of the expression and distribution of CRP2 in olfactory stem cells.

关键词： cysteine- and glycine-rich protein-2 liM domain subcellular localization olfactory stem cells

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relationship of cerebral microbleeds to inflammatory marker levels

引用

Neuroimmunology and Neuroinflammation 2017年第8期4卷 145-151页

作者： qiao-li lu Chen li Ying Song liang Wang Zhi-Rong Jia Department of Neurology Tianjin 5th Center HospitalTianjin 300450China Department of Neurosurgery Tianjin 5th Center HospitalTianjin 300450China Department of Neurology Peking University First HospitalBeijing 100034China

Aim: The purpose of this study is to investigate the incidence, distribution and risk factors of cerebral microbleeds (CMBs) and the relation between CMBs and inflammation in ischemic cerebrovascular disease. Methods: Two hundred and one patients without acute infarction or transient ischemic attack were enrolled. The presence and number of CMB were assessed on susceptibility-weighted imaging. The traditional risk factors of CMB were recorded. Levels of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and matrix metalloproteinase-9 (MMP-9) were tested. Logistic regression analyses were used for multiple-factor analysis of risk factors of CMB. Results: Of the 201 patients, 49 (24.38%) had CMB. Multivariate logistic regression analyses showed that the age, the prevalence of hypertension, silent lacunar infarction, white matter lesion, Montreal Cognitive Assessment Score, the using rate of antithrombotic drugs and levels of hs-CRP, IL-6, MMP-9 were the risk factors for CMB. After adjustments for traditional risk factors, inflammatory marker levels remained to be associated with CMBs. The adjusted odd ratios of hs-CRP, IL-6 and MMP-9 were 1.745 (1.342-2.270), 1.223 (1.018-1.533) and 1.284 (1.082-1.423), respectively. Furthermore, inflammatory marker levels were the risk factor for deep or infratentorial CMBs and lobar CMBs. Conclusion: The age, prevalence of hypertension, silent lacunar infarction, white matter lesion, MoCA Score, the using rate of antithrombotic drugs and serum hs-CRP, IL-6, and MMP-9 levels were the independent risk factors for CMBs.

关键词： Cerebral microbleed traditional risk factor inflammatory marker level susceptibility-weighted imaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of Bubbles on Mechanical Performances in a Borosilicate Glass

引用

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 25-29页

作者： li Chengxing li Dongfeng MA Shilong qiao Ang ZHENG Qingshuang China Helicopter Research and Development Institute Jingdezhen 333001China State Key Laboratory of Silicate Materials for Ar-chitectures Wuhan University of TechnologyWuhan 430070China

To analyze the impact of bubbles on the mechanical behavior of glasses,by controlling the refining time,we prepared three borosilicate glasses with the same composition and different *** the analysis software integrated within the optical microscope,the diameter and number of the bubbles on the surface of three borosilicate glasses were *** the hardness and crack initiation resistance(CR),we built the relationship between the porosity and the mechanical performance of these borosilicate glasses.

关键词： bubbles oxide glass hardness creak initiation resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

改进的多处理器混合关键性系统可调度性分析

引用

北京航空航天大学学报 2016年第9期42卷 1918-1926页

作者：陈瑶李峭鲁俊熊华钢北京航空航天大学电子信息工程学院北京100083

针对混合关键性系统的多重认证需求,研究多核处理器平台中全局调度算法fixed-priority and Earliest Deadline First by Virtual Deadline(fp EDF-VD)的可调度性分析问题。fp EDF-VD结合处理器利用率和虚拟截止期两个方面来计算任务优先... 详细信息

针对混合关键性系统的多重认证需求,研究多核处理器平台中全局调度算法fixed-priority and Earliest Deadline First by Virtual Deadline(fp EDF-VD)的可调度性分析问题。fp EDF-VD结合处理器利用率和虚拟截止期两个方面来计算任务优先级,系统可调度性取决于是否存在可行的虚拟截止期调整参数。考虑到现有可调度分析方法仅测试有限数量的调整参数候选值,不能有效地判定系统可调度性,故提出了一种改进的判定方法。该方法基于传统(非混合关键)任务调度算法fp EDF的可调度利用率约束条件,利用函数图像分析研究不同关键性级别的系统可调度性需求,并在此基础上给出有效虚拟截止期调整参数的确切范围。通过实例分析及与现有判定方法的比较,验证了该方法的正确性和高效性。与理论分析一致,基于随机生成任务集的仿真实验结果表明改进后的方法具有更优越的可调度性能,能显著地提高任务集的可调度接受率。

关键词：实时系统混合关键性多处理器全局调度最早截止时间优先可调度性分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

连续实时血糖监测避免胰岛素强化治疗低血糖发生的价值

引用

第二军医大学学报 2016年第12期37卷 1578-1581页

作者：李亚红乔鲁军胜利油田中心医院重症医学科东营257034

胃肠手术患者术后胃肠道存在损伤,为避免对胃肠道的功能造成影响,促进胃肠道加速修复,术后一段时间需禁饮、禁食。为满足机体营养需求,禁饮禁食的患者只能采用肠外营养支持,但应激状态下患者易发生应激性高血糖或胰岛素抵抗,影响患者术... 详细信息

胃肠手术患者术后胃肠道存在损伤,为避免对胃肠道的功能造成影响,促进胃肠道加速修复,术后一段时间需禁饮、禁食。为满足机体营养需求,禁饮禁食的患者只能采用肠外营养支持,但应激状态下患者易发生应激性高血糖或胰岛素抵抗,影响患者术后恢复并增加并发症的发生率。因此,临床多在术后同时进行胰岛素强化治疗来控制血糖,但这会导致低血糖发生率的上升。

关键词：连续实时血糖监测胃肠外营养胰岛素强化治疗胃肠手术低血糖症

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

引用

Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting li Wei Zhang Jian Wu Hui Hong Wei Quan Xinyu qiao Chun Cui Chenmeng qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Infrared small target detection based on spatial attention density peaks searching

引用

Optoelectronics Letters 2025年第2期21卷 90-96页

作者： RAO Junmin lu Siyu liU Shijian li Fanming CAS Key Laboratory of Infrared System Detection and Imaging Technology Shanghai Institute of Technical Physics University of Chinese Academy of Sciences Shanghai Institute of Technical Physics Chinese Academy of Sciences School of Information Science and Technology Shanghai Tech University

The detection of small targets poses a significant challenge for infrared search and tracking (IRST) systems,as they must strike a delicate balance between accuracy and *** this paper,we propose a detection algorithm based on spatial attention density peaks searching (SADPS) and an adaptive window selection ***,the difference-of-Gaussians (DoG) filter is introduced for preprocessing raw infrared ***,the image is processed by ***,an adaptive window selection scheme is applied to obtain window templates for the target scale ***,the small target feature is used to enhance the target and suppress the ***,the true targets are segmented through a *** experimental results show that compared with the seven state-of-the-art small targets detection baseline algorithms,the proposed method not only has better detection accuracy,but also has reasonable time consumption.

关键词： Infrared imaging

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：