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Bioaccumulation and Biodegradation of Sulfamethazine in Chlorella pyrenoidosa

Journal of Ocean University of China 2017年第6期16卷 1167-1174页

作者： SUN Ming lin Hong GUO Wen ZHAO Fazhen li Jian College of Food Science and Engineering Ocean University of China Qingdao 266003 P. R. China Marine Biology Institute of Shandong Province Qingdao 266104 P. R. China Key Laboratory of Sustainable Development of Marine Fisheries Ministry of Agriculture Yellow Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Qingdao 266071 P. R. China

Intensive use of sulfamethazine(SM_2) in aquaculture has resulted in some detrimental effects to non-targeted organisms. In order to assess its potential ecological risk, it is crucial to have a good understanding on the bioaccumulation and biodegradation of SM_2 in Chlorella pyrenoidosa. The microalgae were treated with 2, 4, and 8 mg L^(-1) of sulfamethazine for 13 days, respectively, showing that the inhibition effects of sulfamethazine on the growth of Chlorella pyrenoidosa increased progressively as the concentrations of sulfamethazine increasing from 2 to 8 mg L^(-1). The peak concentrations of sulfamethazine accumulated in C. pyrenoidosa were 0.225, 0.325, and 0.596 ng per mg FW on day 13 for three treatment groups, respectively, showing a great ability to deplete sulfamethazine from the culture media. On day 13, the percentages of biotic degradation were 48.45%, 60.21% and 69.93%, respectively. The EC_(50) of 10.05 mg L^(-1) was derived which showed no significant risk for C. pyrenoidosa with a calculated risk quotient < 1. The activities of superoxide dismutase and catalase increased progressively in response to sulfamethazine and showed a positive correlation to the treatment concentrations. The highest superoxide dismutase activity was achieved at the concentration of 8 mg L^(-1) after 2 d of exposure, which was 1.89 folds higher than that of the control. The activity of catalase has a similar pattern to that of superoxide dismutase with the maximum activity achieved at day 2, which was 3.11 folds higher compared to that of the control. In contrast to superoxide dismutase and catalase, the maximum glutathione S-transferase activity was observed at day 6, showing 2.2 folds higher than that of the control.

关键词： sulfamethazine Chlorella pyrenoidosa bioaccumulation biodegradation risk assessment

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Neurotoxic role of interleukin-17 in neural stem cell differentiation after intracerebral hemorrhage

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Neural Regeneration Research 2020年第7期15卷 1350-1359页

作者： Lu Gao ping-ping li Tian-Yu Shao Xiang Mao Hao Qi Bing-Shan Wu Ming Shan Lei Ye Hong-Wei Cheng Department of Neurosurgery First Affiliated Hospital of Anhui Medical University

Interleukin 17(IL-17)and its main producer,T cell receptorγδcells,have neurotoxic effects in the pathogenesis of intracerebral hemorrhage(ICH),aggravating brain *** investigate the correlation between IL-17 and ICH,we dynamically screened serum IL-17 concentrations using enzyme-linked immunosorbent assay and explored the clinical values of IL-17 in ICH *** was a significant negative correlation between serum IL-17 level and neurological recovery status in ICH patients(r=–0.498,Plish an ICH model by injecting autologous blood into the caudate ***,the mice were treated with mouse neural stem cells(NSCs)and/or IL-17 neutralizing antibody for 72 *** cytometry,brain water content detection,Nissl staining,and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling results indicated that NSC transplantation significantly reduced IL-17 expression in peri-hematoma tissue,but there was no difference in T cell receptorγδ*** with the ICH group,there were fewer apoptotic bodies and more Nissl bodies in the ICH+NSC group and the ICH+NSC+IL-17 *** investigate the potential effect of IL-17 on directional differentiation of NSCs,we cultured mouse NSCs(NE-4 C)alone or co-cultured them with T cell receptorγδcells,which were isolated from mouse peripheral blood mononuclear cells,for 7 *** results of western blot assays revealed that IL-17 secreted by T cell receptorγδcells reduced the differentiation of NSCs into astrocytes and neurons,while IL-17 neutralization relieved the inhibition of directional differentiation into astrocytes rather than *** conclusion,serum IL-17 levels were elevated in the early stage of ICH and were negatively correlated with outcome in ICH *** experiments and cytological investigations therefore demonstrated that IL-17 probably has neurotoxic roles in ICH because of its inhibitory effects

关键词： antibody neutralization astrocytes directional differentiation interleukin 17 intracerebral hemorrhage neural stem cells Nissl staining recovery T cell receptorγδcells TUNEL staining

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Near-microscopic grain boundary facilitates fatigue crack propagation in a polycrystalline Al–Zn–Mg–Cu alloy

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Progress in Natural Science:Materials International 2023年第1期33卷 120-125页

作者： Kai Wen Xiwu li Baiqing Xiong Haitao lin Qinghong Wen Yanan li Hongwei Yan lizhen Yan Yongan Zhang Zhihui li Hongwei liu State Key Laboratory of Nonferrous Metals and Processes China GRINM Group Co. LTD. GRIMAT Engineering Institute Co. LTD. General Research Institute for Nonferrous Metals Southwest Aluminum(Group) Co. Ltd.

In present study, grain characteristics with sizes within 10–30 μm were fabricated from a same Al–Zn–Mg–Cu alloy, FCP behaviors of the alloys with small grain(SG alloy), medium grain(MG alloy) and large grain(LG alloy)were investigated and related fatigue fracture morphology was analyzed. With the enhancement of stress intensity factor range(ΔK), the alloy with larger grains possessed faster FCP rate, which were successively arranged as SG alloy > MG alloy > LG alloy at initial stage while turned to LG alloy > MG alloy > SG alloy at final stage for the stable expanding region. Except for conventional characteristics of striations, tearing ridges, secondary cracks,second phases, voids and dimples, more prominent grain boundary features appeared on fracture surface, especially for MG and LG alloy. The calculation of cyclic plastic zone(CPZ) sizes proved that grain boundary participated and promoted FCP behavior when CPZ covered grain and grain boundary together.

关键词： Fatigue crack propagation Grain size Grain boundary Cyclic plastic zone Al–Zn–Mg–Cu alloy

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Fabrication of triple-shelled hollow spheres with optical properties via RAFT polymerization

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Chinese Chemical Letters 2010年第7期21卷 864-867页

作者： li ping Wang li Min Zhao Wen Zhi li Rui Qing Chu Long Tan Xiu Xiu Zhao Gang Wang College of Materials Science and Engineering Liaocheng UniversityLiaocheng 252059China

The triple-shelled hollow spheres with optical properties were prepared via reversible addition-fragmentation chain transfer (RAFT) *** removal the core templates of the poly(styrene),the hollow silica spheres were *** coating process of poly(methyl methacrylate)(PMMA) on the hollow silica spheres surface via surface RAFT polymerization was performed *** polymers coated on the hollow spheres surfaces were end-functionalized by trithiocarbonate,and they were used as RAFT agent to proceed the chain extension polymerization using Tb complex as *** samples were characterized by FT-IR,SEM and luminescence spectroscopy *** results indicated that the triple-shelled hollow spheres had been prepared successfully and the average diameter of the hollow core was about 1μm.

关键词： Hollow spheres Optical properties Polymers Surfaces Luminescence

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Construction of a virtual lunar environment platform

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International Journal of Digital Earth 2013年第5期6卷 469-482页

作者： Min Chen Hui lin Yongning Wen li He Mingyuan Hu Institute of Space and Earth Information Science The Chinese University of Hong KongHong KongChina Key Laboratory of Virtual Geographic Environment(Ministry of Chinese Education) Nanjing Normal UniversityNanjingChina

Many of the world’s powerful and wealthy nations,including China,have devoted both large amounts of funding and considerable promotion to lunar research and *** launch of Chinese Chang’e-1 satellite and the construction of the scientific observation data platform created a favourable opportunity for research into the lunar geometrical,physical and chemical *** on this background,a Wide Area Network(WAN)based virtual lunar environment was constructed for observation data sharing and further *** systematic architecture and framework were introduced and then strategies of mass data(*** digital elevation model,lunar digital orthophoto map and typical thematic lunar data)organisation,integration,management and scheduling were then set up to achieve the 3D visualisation of typical lunar geomorphic ***,the integration method of 3D lunar data and the process model of impact craters were studied;thus,the whole lunar and celestial collision process could be dynamically *** results indicate that the WAN-based virtual lunar platform can be used effectively for public information sharing,scientific exploration and further to promote the development of deep space exploration in China.

关键词： virtual lunar environment Chang’e-1 satellite platform construction digital earth

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Generation of azaarene nitrile oxides from methyl azaarenes and t-BuONO enabling the synthesis of furoxans and 1,2,4-oxadiazoles

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Organic Chemistry Frontiers 2022年第4期9卷 1121-1126页

作者： Xiang-Jin Zhang Jian-Kang Cao Jun-Jie Ren lin Hong Ru-Jin liang Kai-Yan Hao Kai-li Wei Bao-Jing Mi Yue liu Yan-ping Zhu School of Pharmacy Key Laboratory of Molecular Pharmacology and Drug EvaluationMinistry of EducationCollaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of ShandongYantai UniversityShandongYantai264005P.R.China

A high-efficiency strategy for the synthesis of furoxans and 1,2,4-oxadiazoles has been developed,using tert-butyl nitrite(TBN)as the nitrogen *** nitrile oxides as activated intermediates were generated in situ via m... 详细信息

关键词： oxides synthesis

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Alphabet of one-loop Feynman integrals

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Chinese Physics C 2022年第9期46卷 48-61页

作者： Jiaqi Chen Chichuan Ma li lin Yang Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Zhejiang Institute of Modern Physics Department of PhysicsZhejiang UniversityHangzhou 310027China

In this paper, we present the universal structure of the alphabet of one-loop Feynman integrals. The letters in the alphabet are calculated using the Baikov representation with cuts. We consider both convergent and divergent cut integrals and observe that letters in the divergent cases can be easily obtained from convergent cases by applying certain limits. The letters are written as simple expressions in terms of various Gram determinants. The knowledge of the alphabet enables us to easily construct the canonical differential equations of the d log form and aids in bootstrapping the symbols of the solutions.

关键词： Baikov representation Alphabet UT basis

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Pompon-like NiCo_(2)O_(4) nanospheres:a potential candidate for the counter electrode in quantum dot-sensitized solar cells

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Tungsten 2023年第2期5卷 235-246页

作者： Qiu Zhang Ting-Ting Zhang Feng-Yan li lin Xu Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education Faculty of ChemistryNortheast Normal UniversityChangchun 130024China

To find a novel counter electrode(CE)material for quantum dot-sensitized solar cells(QDSSCs),pompon-like NiCo_(2)O_(4) nanospheres are synthesized by a facile solvothermal and post-calcination method and we attempt to apply it as a CE material for QDS *** catalytic performance of NiCo_(2)O_(4) counter electrode is investigated in detail through electrochemical impedance spectroscopy,Tafel test and cyclic *** catalytic activity of NiCo_(2)O_(4) CE is superior to that of nanoflower-like Cu2S CE and traditional Cu2S/brass CE,which is mainly attributed to the large specific surface area,outstanding electrical conductivity of bimetallic oxides and the synergistic promotion effect of metals with different valence *** standard sunlight(air mass AM 1.5G 100 mW·cm^(-2)),the CdS/CdSe/ZnS-sensitized solar cell assembled with NiCo_(2)O_(4) CE achieved a photoelectric conversion efficiency of 5.55%,with a short current density of 22.49 mA·cm^(-2),an open circuit voltage of 0.574 V,and a fill factor of 0.43,which is slightly higher than the QDSSCs with nanoflower-like Cu_(2)S CE(4.75%)and traditional Cu_(2)S/brass CE(4.69%).This research provides ideas for discovering innovative and efficient CE materials for QDSSCs.

关键词： QDSSCs Counter electrodes NiCo_(2)O_(4) Cu_(2)S

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Degree-of-Node Task Scheduling of Fine-Grained Parallel Programs on Heterogeneous Systems

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Journal of Computer Science & Technology 2019年第5期34卷 1096-1108页

作者： Han lin Ming-Fan li Cheng-Fan Jia Jun-Nan liu Hong An School of Computer Science and Technology University of Science and Technology of ChinaHefei 230026China

Processor specialization has become the development trend of modern processor industry. It is quite possible that this will still be the main-stream in the next decades of semiconductor era. As the diversity of heterogeneous systems grows, organizing computation efficiently on systems with multiple kinds of heterogeneous processors is a challenging problem and will be a normality. In this paper, we analyze some state-of-the-art task scheduling algorithms of heterogeneous computing systems and propose a Degree of Node First (DONF) algorithm for task scheduling of fine-grained parallel programs on heterogeneous systems. The major innovations of DONF include: 1) simplifying task priority calculation for directed acyclic graph (DAG) based fine-grained parallel programs which not only reduces the complexity of task selection but also enables the algorithm to solve the scheduling problem for dynamic DAGs;2) building a novel communication model in the processor selection phase that makes the task scheduling much more efficient. They are achieved by exploring finegrained parallelism via a dataflow program execution model, and validated through experimental results with a selected set of benchmarks. The results on synthesized and real-world application DAGs show a very good performance. The proposed DONF algorithm significantly outperforms all the evaluated state-of-the-art heuristic algorithms in terms of scheduling length ratio (SLR) and efficiency.

关键词： task scheduling heterogeneous system performance parallel program

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Arabidopsis Phytochrome D Is Involved in Red light-Induced Negative Gravitropism of Hypocotyles

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Journal of Integrative Agriculture 2014年第8期13卷 1634-1639页

作者： li Jian-ping HOU Pei ZHENG Xu SONG Mei-fang SU liang YANG Jian-ping Institute of Crop Sciences Chinese Academy of Agricultural Sciences Institute of Nuclear and Biotechnology Xinjiang Academy of Agricultural Sciences Graduate School Chinese Academy of Agricultural Sciences

The phytochrome gene family, which is in Arabidopsis thaliana, consists of phytochromes A-E（phyA to phyE）, regulates plant responses to ambient light environments. PhyA and phyB have been characterized in detail, but studies on phyC to phyE have reported discrepant functions. In this study, we show that phyD regulates the Arabidopsis gravitropic response by inhibiting negative gravitropism of hypocotyls under red light condition. PhyD had only a limited effect on the gravitropic response of roots in red light condition. PhyD also enhanced phyB-regulated gravitropic responses in hypocotyls. Moreover, the regulation of hypocotyl gravitropic responses by phyD was dependent upon the red light fluence rate.

关键词： phytochrome D gravitropism Arabidopsis thaliana

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