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Modeling structured peer-to-peer systems

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The Journal of China Universities of Posts and Telecommunications 2006年第3期13卷 76-80页

作者： HAN li LEI zhen-ming Information Engineer Institute Beijing University of Posts and Telecommunications Beijing 100876 China

Distributed network architecture and dynamic change of nodes makes the operation of structured peer-to-peer networks unpredictable. This article aims to present a research on the running rule of structured peer-to-peer networks through a mathematical model. The proposed model provides a low-complexity means to estimate the performance of a structured peer-to-peer network from two aspects： the average existent time of a node and probability of returning to a temporarily steady state of network. On the basis of the results, it can be concluded that the proposed structured peer-to-peer network is suitable for those conditions where the frequency of node change is under limited value, and this value mainly depends on the initializing time of the node. Otherwise, structured peer-to-peer network can be abstracted as a network queuing system, which is composed of many node queuing systems in a meshy way and the relation between the throughput of the node system and network system is analyzed.

关键词： peer-to-peer network distributed hash table bith and death Markov model average existent time temporarily steady state

Molecular Spectrum ofα-andβ-Thalassemia among Young Individuals of Marriageable Age in Guangdong Province,China

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Biomedical and Environmental Sciences 2021年第10期34卷 824-829页

作者： ZHOU Bing Yi& WANG Yong Xia XU Shan Shan GU Heng li ming zhen NHC Key Laboratory of Male Reproduction and Genetics Family Planning Research Institute of Guangdong ProvinceGuangzhou 510060GuangdongChina

Thalassemia is a group of genetically heterogeneous diseases characterized by hemolytic *** investigate molecular characteristics ofα-andβ-thalassemia among young individuals of marriageable age in Guangdong Province,24,788 subjects with suspected thalassemia were genetically tested forα-andβ-thalassemia by GapPCR and reverse dot blot during 2018–*** suspected rare thalassemia cases,DNA sequencing was performed to identify rare and unknown thalassemia gene mutations.A total of 14,346 thalassemia carriers were detected,including 7,556 cases ofα-thalassemia with 25 genotypes and 8α-gene mutations identified,5,860 cases ofβ-thalassemia with 18 genotypes and 18β-gene mutations identified,and 930 cases of compoundα/β-*** them,the frequency of--SEA deletion was the highest inα-thalassemia(66.01%),followed by-α3.7(17.98%)and-α.24(8.22%),and the frequency of CD41-42(-TCTT)mutation was the highest inβ-thalassemia(38.38%),followed by IVS-II-654(C>T)(25.67%),-28(A>G)(15.76%),and CD17(10.01%).In addition,5 rare mutations(--THAI and HKαα,CD113,-90,and CD56)were found in the study *** results revealed molecular epidemiological background ofα-andβ-thalassemia in Guangdong Province,which can support optimization of thalassemia prevention and control *** demonstrated that thalassemia is heterogeneous with significant geographical differences and population specificity.

关键词： Guangdong prevention marriage

Effectiveness of Using Mean Corpuscular Volume and Mean Corpuscular Hemoglobin for Beta-thalassemia Carrier Screening in the Guangdong Population of China

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Biomedical and Environmental Sciences 2021年第8期34卷 667-671页

作者： GU Heng WANG Yong Xia DU Meng Xuan XU Shan Shan ZHOU Bing Yi li ming zhen NHC Key Laboratory of Male Reproduction and Genetics Family Planning Research Institute of Guangdong ProvineeGuangzhou 510000GuangdongChina Department of Public Health and Preventive Medicine Jinan UniversityGuangzhou 510000GuangdongChina

Beta(β)-thalassemia is one of the most common hemoglobinopathies worldwide,creating major public health problems and social burdens in many *** forβ-thalassemia carriers is crucial for controlling this *** investigate the?effectiveness?of?mean?corpuscular?volume?(MCV)and mean corpuscular hemoglobin(MCH)for screeningβ-thalassemia,retrospective data were analyzed for 6,779β-thalassemia carriers subjected to genetic testing following thalassemia screening in Guangdong province between January 2018 and December 2019.

关键词： Guangdong Population thalassemia

REACTION OF α-(1H-1,2,4-TRIAZOL-1-YL)ACETOPHENONE WITH PHENYL ISOTHIOCYANATE

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Chinese Chemical Letters 1993年第9期4卷 763-766页

作者： zheng ming li zhen Nian HUANG Institute of Elemento-Organic Chemistry,Nankai University,Tianjin,300071

Reaction of α-(1H-1,2,4-triazol-1-yl)acetophenone with phenyl isothiocyanate in the presence of a base and subse- quent alkylation leads to the ketene S,N-acetal(2),(4),(7), (8);thiazolidone(3),thiazolidine(5)and 1,3... 详细信息

关键词： Ph TRIAZOL-1-YL)ACETOPHENONE WITH PHENYL ISOTHIOCYANATE REACTION OF Rev

Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy

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Chinese Medical Journal 2009年第21期122卷 2580-2586页

作者： li Chun-jun ZHANG Qiu-mei li ming-zhen ZHANG Jing-yun YU Pei YU De-min The Ministry of Health Key Laboratory of Hormone and Development Department of Endocrinology Metabolic Disease Hospital of Tianjin Medical University Tianjin 300070 China

Background Cardiac failure is a leading cause of the mortality of diabetic patients. In part this is due to a specific cardiomyopathy, referred to as diabetic cardiomyopathy. Oxidative stress is widely considered to be one of the major factors underlying the pathogenesis of the disease. This study aimed to test whether the antioxidant α-lipoic acid （α-LA） could attenuate mitochondrion-dependent myocardial apoptosis through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy. Methods A rat model of diabetes was induced by a single tail intravenous injection of streptozotocin （STZ） 45 mg/kg. Experimental animals were randomly assigned to 3 groups： normal control （NC）, diabetes （DM） and DM treated with α-LA （α-LA）. The latter group was administered with a-LA （100 mg/kg ip per day）, the remainder received the same volume vehicle. At weeks 4, 8, and 12 after the onset of diabetes, cardiac apoptosis was examined by TUNEL assay. Cardiomyopathy was evaluated by assessment of cardiac structure and function. Oxidative damage was evaluated by the content of malondialdehyde （MDA）, reduced glutathione （GSH） and the activity of manganese superoxide diamutase （Mn-SOD） in the myocardial mitochondria. Expression of caspase-9 and caspase-3 proteins was determined by immunohistochemistry and mitochondrial cytochrome c release was detected by Western blotting Results At 4, 8, and 12 weeks after the onset of diabetes, significant reductions in TUNEL-positive cells, caspase-9,-3 expression, and mitochondrial cytochrome c release were observed in the α-LA group compared to the DM group. In the DM group, the content of MDA in the myocardial mitochondria was significantly increased, and there was a decrease in both the mitochondrial GSH content and the activities of Mn-SOD. They were significantly improved by α-LA treatment. HE staining displayed structural abnormalities in diabetic hearts, while α-LA reversed this structural derangement. The index of cardiac fun

关键词： alpha-lipoic acid myocardial apoptosis mitochondrial oxidative stress diabetic cardiomyopathy

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无人值班变电站遥控常见故障的分析与处理

电力系统保护与控制 2009年第18期37卷 145-146页

作者：李雨舒李明珍吉安供电公司江西吉安343000 赣州供电公司江西赣州341000

随着电力系统的快速发展,变电站数量的日益增多,如何准确快速地分析与处理遥控常见故障,一直是自动化维护人员所关注的问题。根据遥控原理,通过对无人值班变电站遥控操作过程的分析,总结了此过程中出现的常见故障,并就故障出现的原因进... 详细信息

随着电力系统的快速发展,变电站数量的日益增多,如何准确快速地分析与处理遥控常见故障,一直是自动化维护人员所关注的问题。根据遥控原理,通过对无人值班变电站遥控操作过程的分析,总结了此过程中出现的常见故障,并就故障出现的原因进行了分析,提出了有针对性的处理方法。

关键词：变电站遥控故障分析处理

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变电站遥测常见故障查找及处理方法

电力系统保护与控制 2009年第4期37卷 90-92页

作者：李明珍李雨舒赣州供电公司江西赣州341000 吉安供电公司江西吉安343000

如何准确快速地查找和处理遥测常见故障,一直是人们所关注的问题。根据采样信号的不同,采样方法可分为直流采样和交流采样。本文在衡量直流采样和交流采样利弊的基础上,结合远动系统的运行和维护实际经验,重点讨论交流采样方式下遥测回... 详细信息

如何准确快速地查找和处理遥测常见故障,一直是人们所关注的问题。根据采样信号的不同,采样方法可分为直流采样和交流采样。本文在衡量直流采样和交流采样利弊的基础上,结合远动系统的运行和维护实际经验,重点讨论交流采样方式下遥测回路常见故障的查找和处理方法。

关键词：遥测故障查找处理方法

Mitochondrial gene mutations and type 2 diabetes in Chinese families

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Chinese Medical Journal 2008年第8期121卷 682-686页

作者： li ming-zhen YU De-min YU Pei liU De-min WANG Kun TANG Xin-zhi Department of Endocrinology Health Ministry Key Laboratory Hormones and Development Metabolic Disease Hospital Tianjin Medical University Tianjin 300070 China Department of Biochemistry Tianjin Medical University Tianjin 300070 China

Background Numerous mitochondrial DNA mutations are significantly correlated with development of diabetes. This study investigated mitochondrial gene, point mutations in patients with type 2 diabetes and their families. Methods Unrelated patients with type 2 diabetes （n=826） were randomly recruited; unrelated and nondiabetic subjects （n=637） served as controls. The clinical and biochemical data of the participants were collected. Total genome was extracted from peripheral leucocytes. Polymerase chain reaction, restriction fragment length poiymorphism （PCR-RFLP） and cloning techniques were used to screen mitochondrial genes including np3316, np3394 and np3426 in the ND1 region and np3243 in the tRNA^Leu（UUR）. Results In 39 diabetics with one or more mitochondrial gene point mutations, the prevalence （4.7%, 39/826） of mtDNA mutations was higher than that （0.7%, 5/637） in the controls. The identical mutation was found in 23 of 43 tested members from three pedigrees. Affected family members presented with variable clinical features ranging from normal glucose tolerance to impaired glucose tolerance （IGT）（n=2）, impaired fasting glucose （IFG）（n=1） to type 2 diabetes （n=13） with 3 family members suffering from hearing loss. Conclusions Type 2 diabetes in China is associated with several mitochondrial gene mutations. Aged patients with diabetic family history had a higher prevalence of mutation and various clinical pictures. Mitochondrial gene mutation might be one of the genetic factors contributing to diabetic familial clustering.

关键词： mitochondrial DNA gene mutation type 2 diabetes

Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai li zhen Ma Jin-Hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High Magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity