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Activin A receptor type 1C single nucleotide polymorphisms associated with esophageal squamous cell carcinoma risk in Chinese population

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 39-51页

作者： Si-Yun lin Hou Huang Jin-Jie Yu Feng Su Tian Jiang Shao-Yuan Zhang Lu Lv Tao Long Hui-Wen Pan Jun-Qing Qi Qiang Zhou Wei-Feng Tang Guo-Wen Ding li-ming Wang li-Jie Tan Jun Yin Department of Thoracic Surgery Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Affiliated to Fudan UniversityShanghai 200040China Department of Cardiothoracic Surgery The Affiliated People's Hospital of Jiangsu UniversityZhenjiang 212002Jiangsu ProvinceChina Department of Thoracic Surgery Sichuan Cancer Hospital&InstituteChengdu 610042Sichuan ProvinceChina Department of Cardiothoracic Surgery Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Respiratory and Critical Care Medicine Shanghai Xuhui Central HospitalShanghai 200032China

BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and *** A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent *** To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han *** In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were *** SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction ***-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were *** Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male *** the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to *** ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.

关键词： Activin A receptor type 1C Single nucleotide polymorphisms Esophageal squamous cell carcinoma Genetic susceptibility Hospital-based cohort study

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Is it possible to foot reflexology for infants with sensorineural hearing loss?

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World Journal of Clinical Cases 2025年第2期13卷 1-4页

作者： Min Ai Hang-Hang Zhang Jun-Bang Feng Chuan-ming li Wen-Jing Wang Meng-Die Hu Department of Anesthesiology Nanan District People's Hospital of ChongqingChongqing 400060China Department of Breast and Thyroid Surgery Chongqing Bishan District Maternal and Child Health Care HospitalChongqing 402760China Department of Medical Imaging Chongqing University Central HospitalChongqing 400014China

Foot reflexology is a non-invasive and safe complementary therapy that works by massaging the reflex zones of the feet and exerts systemic or whole-body regulation through meridian nerve *** therapy is commonly used in the treatment of various conditions such as autism and Parkinson's ***,there is limited reporting on the use of foot reflexology therapy for infants with sensorineural hearing loss(SNHL).Currently,there is no definitive conclusion on how foot reflexology therapy can influence *** editorial holds some guiding significance regarding this clinical *** aim is to present physiological evidence of how foot reflexology therapy can impact infants with SNHL,thereby enhancing clinician’s awareness of foot reflexology in treating infants with SNHL.

关键词： Foot reflexology Sensorineural Hearing Loss Future perspectives limitations Neural conduction

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对抗性增强的图像块位平面拆分缩略图保留加密

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河南师范大学学报（自然科学版） 2025年第1期53卷 92-99页

作者：李名崔清晨王曦张静李文泽河南师范大学计算机与信息工程学院河南新乡453007 河南师范大学河南省教育人工智能与个性化学习重点实验室河南新乡453007

随着个人图像数量日益增加,云服务开始在图像存储方面发挥重要作用.然而,将图像上传到云端将会面临隐私威胁.传统的加密方案对图像进行简单加密就可以保护图像隐私,但它牺牲了图像内容的可用性.近年来,缩略图保留加密(thumbnail preserv... 详细信息

随着个人图像数量日益增加,云服务开始在图像存储方面发挥重要作用.然而,将图像上传到云端将会面临隐私威胁.传统的加密方案对图像进行简单加密就可以保护图像隐私,但它牺牲了图像内容的可用性.近年来,缩略图保留加密(thumbnail preserving encryption,TPE)被提出,通过加密后保持缩略图不变使云中图像在不被非法第三方肉眼识别的同时能对用户具有可用性.但是现有的TPE方案没有考虑到机器学习对图像的隐私威胁.基于此,提出了一种新的TPE方案,该方案在加密过程中从对抗深度学习模型识别图像这一全新的角度出发,提高了保护图像隐私信息的能力.实验表明,所提出的方案能够在图像对用户具有可用性的同时抵抗人类肉眼和深度神经网络识别图像.

关键词：图像加密对抗性可用性隐私性

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Lateral habenula neurocircuits mediate the maternal disruptive effect of maternal stress: A hypothesis

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Zoological Research 2022年第2期43卷 166-175页

作者： ming li Department of Psychology University of Nebraska-LincolnLincolnNE 68588USA

Up to 20%of women experience stress-related disorders during the postpartum period;however,little is known about the specific neural circuitry by which maternal stress exerts its negative impacts on mental health and maternal caregiving ***,such a circuitry should serve as an interface between the stress response system and maternal neural network,transmitting stress signals to the neural circuitry that mediates maternal *** this paper,I propose that the lateral habenula(LHb)serves this interface *** shows that the LHb plays a key role in encoding stress-induced effects and in the pathophysiology of major depression and stressrelated anxiety,and thus may play a role in maternal behavior as part of the maternal brain network.I hypothesize that maternal stress acts upon the LHb and two of its major downstream targets,i.e.,ventral tegmental area(VTA)and dorsal raphe nucleus(DRN),compromising the maternal care and contributing to postpartum mental *** hypothesis makes three predictions:(1)maternal stress enhances LHb neuronal activity;(2)activation of DRN-and VTA-projecting neurons in the LHb mimics the detrimental effects of maternal stress on maternal behavior;and(3)suppression of DRN-and VTA-projecting neurons in the LHb attenuates the detrimental effects of maternal stress on maternal care in stressed *** of this hypothesis is expected to enhance our understanding of the neurocircuit mechanisms mediating stress effects on maternal behavior.

关键词： Maternal behavior Lateral habenula(LHb) Ventral tegmental area Dorsal raphe Maternal stress Postpartum depression Postpartum anxiety

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Nonlinear Adaptive Robust Control Design for Static Synchronous Compensator Based on Improved Dynamic Surface Method

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International Journal of Automation and computing 2014年第3期11卷 334-339页

作者： Wen-Lei li ming-ming li School of Information Science and Engineering Ningbo University

In view of single machine to infinite bus system with static synchronous compensator, which is affected by internal and external disturbances, a nonlinear adaptive robust controller is constructed based on the improved dynamic surface control method(IDSC). Compared with the conventional DSC, the sliding mode control is introduced to the dynamic surface design procedure, and the parameter update laws are designed using the uncertainty equivalence criterions. The IDSC method not only reduces the complexity of the controller but also greatly improves the system robustness, speed and accuracy. The derived controller cannot only attenuate the influences of external disturbances against system output, but also has strong robustness to system parameters variance because the damping coefficient is considered in the internal parameter uncertainty. Simulation result reveals that the designed controller can effectively improve the dynamic performances of the power system.

关键词： Power systems robust control parameter uncertainty disturbance attenuation dynamic surface control(DSC)

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Review of advanced CMOS technology for post-Moore era

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Science China(Physics,Mechanics & Astronomy) 2012年第12期55卷 2316-2325页

作者： li ming Institute of Microelectronics Peking UniversityBeijing 100871China

The continuous downsizing of device has sustained Moore's law in the past 40 *** the power dissipation becomes more and more serious,a lot of emerging technologies have been adopted in the past decade to solve the short channel effect,leakage and performance degradation *** this paper,the emerging scaling technologies and device innovations,including high-k/metal gate,strain,ultra-shallow junction,tri-gate FinFET,extremely thin SOI and silicon nanowire FET will be reviewed and discussed in terms of the potential and challenge for post-Moore era.

关键词： Moore's law power dissipation performance gain variability HK/MG strain novel device architecture

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Semi-conformal structure on certain vertex super algebras associated to vertex superalgebroids

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Frontiers of Mathematics in China 2019年第5期14卷 881-906页

作者： ming li School of Mathematical Sciences Xiamen UniversityXiamen 361005China

We first give the definition of a vertex *** we construct a family of vertex superalgebras associated to vertex *** the main result,we find a sufficient and necessary condition that these vertex superalgebras are *** addition,we give a concrete example of a semi-conformal vertex superalgebra and apply our results to this superalgebra.

关键词： Vertex superalgebroid vertex superalgebra semi-conformal

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Residual stress distribution in thin diamond films and its effects on preparation of thick freestanding diamond films using DC arc plasma jet operated at gas recycling mode

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中国有色金属学会会刊：英文版 2004年第z1期14卷 255-259页

作者： li Cheng-ming Univ Sci & Technol Beijing Sch Mat Sci & Engn Beijing 100083 Peoples R China

Diamond films produced by chemical vapor deposition show excellent properties. The residual stress distribution of diamond thin films deposited by DC arc plasma jet at recycling mode was analyzed by line shifts of micro Raman spectroscopy. The results show that the compressive residual stress concentrates at the film's edge. The experimental observations show that cracks initiate at the edge of the diamond thick wafer and then propagate towards the center. The residual stress of diamond films increases with the increase of methane concentration and deposition temperature. The difference of adhesion in close area causes more shear stress and brings about the two sides of crack being not at same level. To suppress crack probability, it is favourable for increasing the film thickness and selecting a substrate with lower coefficient of thermal expansion and lower adhesion. The effects of the residual stress distribution on thick diamond films detachment were discussed.

关键词： residual stress diamond films cracking

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Heterogeneous Nucleation on a Conical Cavity

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Chinese Physics Letters 2014年第3期31卷 173-176页

作者： li Xiang-ming School of Materials Science and Engineering Kunming University of Science and Technology Kunming 650093

Heterogeneous nucleation in a conically shaped pit on the surface of a plane surface substrate is investigated. The growing process of a cluster on the substrate consists of three stages： growing within the conical cavity, at the cavity edge and outside the cavity. In every stage, the thermodynamic criterion of a cluster growing into a nucleus depends on both the conical cavity dimensions and the substrate materials. The free energy barrier for nucleus formation and the condition of twice nucleation are obtained.

关键词： NUCLEATION RESEARCH THERMODYNAMICS -- Research FREE energy (Thermodynamics) SOliDIFICATION PHYSICS research

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Electrocatalytic performance of Pd–Ni nanowire arrays electrode for methanol electrooxidation in alkaline media

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Rare Metals 2014年第1期33卷 65-69页

作者： ming-li Xu Faculty of Science Kunming University of Science and Technology

A successful approach to prepare the Pd-Ni nanowire arrays electrode without carbon supports was reported. The morphology and crystallinity of nanowire were characterized by transmission electron microscopy, selected-area electron diffraction （SAED）, X-ray diffrac- tion （XRD）, and X-ray photoelectron spectroscopy （XPS） analyses, respectively. The results show that the diameters of the nanowire are in the range of 65-75 nm, and the polycrystalline binary solid solution alloy is formed in the Pd-Ni nanowire. Cyclic voltammograms, chronoampero- grams, and electrochemical impedance spectroscopy dem- onstrate that the Pd-Ni nanowire arrays electrodes show excellent electrocatalytic performance for methanol oxi- dation in alkaline media. The catalytic activity of Pd-Ni nanowire arrays electrode is ,,~ 1.39 times higher than that of the Pd nanowire arrays electrode and ,,~2.28 times higher than that of the commercial Pd/C catalyst. This is mostly owing to the transfer of electron density from Ni to Pd. These results indicate that Pd-Ni nanowire arrays electrode is very promising in an alkaline direct methanol fuel cell.

关键词： Pd-Ni nanowires Electrocatalyst Methanoloxidation Direct methanol fuel cell Nanowire arrayselectrode

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