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HCRVD: A Vulnerability Detection System Based on CST-PDG Hierarchical Code Representation Learning

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Computers, Materials & Continua 2024年第6期79卷 4573-4601页

作者： Zhihui Song Jinchen Xu kewei li Zheng Shan School of Cyberspace Security Information Engineering UniversityZhengzhou450001China

Prior studies have demonstrated that deep learning-based approaches can enhance the performance of source code vulnerability detection by training neural networks to learn vulnerability patterns in code ***,due to limitations in code representation and neural network design,the validity and practicality of the model still need to be ***,due to differences in programming languages,most methods lack cross-language detection *** address these issues,in this paper,we analyze the shortcomings of previous code representations and neural *** propose a novel hierarchical code representation that combines Concrete Syntax Trees(CST)with Program Dependence Graphs(PDG).Furthermore,we introduce a Tree-Graph-Gated-Attention(TGGA)network based on gated recurrent units and attention mechanisms to build a Hierarchical Code Representation learning-based Vulnerability Detection(HCRVD)*** system enables cross-language vulnerability detection at the *** experiments show that HCRVD surpasses many competitors in vulnerability detection *** benefits from the hierarchical code representation learning method,and outperforms baseline in cross-language vulnerability detection by 9.772%and 11.819%in the C/C++and Java datasets,***,HCRVD has certain ability to detect vulnerabilities in unknown programming languages and is useful in real open-source *** shows good validity,generality and practicality.

关键词： Vulnerability detection deep learning CST-PDG code representation tree-graph-gated-attention network cross-language

3D打印金属垫块或一体化髋臼假体重建髋关节翻修术中骨缺损

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中华骨科杂志 2025年第2期45卷 94-101页

作者：孙博李科伟王少华王爱国梅伟王金良郑州市骨科医院关节病科郑州450000

目的探讨3D打印金属垫块或一体化髋臼假体重建髋关节翻修术中骨缺损的临床疗效。方法回顾性分析2021年6月至2023年7月于郑州市骨科医院行全髋关节翻修的11例患者资料。男5例、女6例,年龄(64.8±10.7)岁(范围58~75岁),体质指数(23.3±4.8... 详细信息

目的探讨3D打印金属垫块或一体化髋臼假体重建髋关节翻修术中骨缺损的临床疗效。方法回顾性分析2021年6月至2023年7月于郑州市骨科医院行全髋关节翻修的11例患者资料。男5例、女6例,年龄(64.8±10.7)岁(范围58~75岁),体质指数(23.3±4.8)kg/m 2(范围21~27 kg/m 2)。髋臼骨缺损Paprosky分型:ⅡA型3例、ⅡB型4例、ⅢA型3例、ⅢB型1例。翻修原因:无菌性松动8例、感染旷置术后3例。使用3D打印金属垫块9例(无菌性松动8例、感染旷置术后1例),使用3D打印一体化髋臼2例(感染旷置术后)。初次置换至翻修的时间为(11.8±5.6)年(范围5~17年)。采用Harris髋关节评分及疼痛视觉模拟评分(visual analogue scale)评估髋关节功能改善及疼痛恢复情况。于骨盆正位X线片上测量双下肢长度差、髋关节旋转中心垂直高度及旋转中心水平位置。结果所有患者均顺利完成手术,手术时间为(145.9±35.5)min(范围110~159 min),术中出血量为(950.5±310.8)ml(范围680~1450 ml)。患者术后Harris髋关节功能评分均升高,与术前比较差异有统计学意义(F=554.085,P<0.001);术后1年Harris髋关节功能评分为(74.36±5.16)分,大于术前的(32.18±4.07)分,差异有统计学意义(P<0.05)。患者术后VAS评分均下降,与术前比较差异有统计学意义(F=177.717,P<0.001);术后1年VAS评分为(1.27±0.65)分,小于术前的(6.18±1.17)分,差异有统计学意义(P<0.05)。术前双下肢长度差为(1.97±0.71)cm,大于末次随访的(0.69±0.52)cm,差异有统计学意义(t=4.824,P<0.001)。术后患侧髋关节旋转中心垂直高度为(1.88±0.46)cm,健侧为(1.67±0.35)cm,差异无统计学意义(t=1.205,P=0.242);术后患侧髋关节旋转中心水平位置为(3.48±0.55)cm,健侧为(3.54±0.32)cm,差异无统计学意义(t=-0.313,P=0.758)。1例术中出现股骨大转子骨折,经复位内固定后3个月愈合。所有患者均获得随访,随访时间为(21.3±9.5)个月(范围15~31个月)。切口均一期愈合,术后3个月均完全负重。末次随访时无一例出现假体松动、脱位及感染;4例有轻度跛行、1例出现异位骨化,患者髋关节屈伸功能均良好,不影响日常生活而未行进一步处理。结论3D打印金属垫块或一体化髋臼假体重建髋臼骨缺损临床疗效满意,可恢复正常髋关节旋转中心,术后并发症发生率低。

关键词：关节成形术,置换,髋再手术假体失效打印,三维

Effect of coordination structure of aluminum on its activation from minerals and Oxisols during their acidification

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Pedosphere 2024年第5期34卷 916-928页

作者： kewei li Yangxiaoxiao SHI Jackson Nkoh NKOH Jun JIANG Renkou XU State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Beijing 100049China

The types and contents of phyllosilicate minerals in soils play an important role in soil acidification,as soil acid buffering capacity varies with the composition of the phyllosilicate *** addition to aluminum-oxygen(Al-O)octahedrons,a certain number of Al-O tetrahedrons exist in phyllosilicate minerals due to the isomorphic substitution of silicon ion(Si4+)by aluminum ion(Al3+)in Si-O tetrahedrons of ***,the effect of the two coordination structures of Al on the release of Al during mineral acidification has not yet been ***,the differences in Al activation in phyllosilicate minerals and soils with different Al coordination structures were investigated through constant-p H experiments and27Al magic-angle spinning nuclear magnetic resonance(MAS-NMR)*** results of27Al MAS-NMR spectra showed that kaolinite contained Al-O octahedrons,phlogopite and illite contained Al-O tetrahedrons,and vermiculite composite contained both octahedral and tetrahedral *** p Hlite>vermiculite composite>phlogopite>kaolinite,which was consistent with the orders of cation exchange capacity and content of tetrahedral Al of the *** to the rate constants,the Al release rates were in the order of phlogopite>illite>vermiculite composite>kaolinite at p H *** for phlogopite,the Al release rates in these minerals increased with decreasing suspension p ***,the Al release contents and rates were greater in phlogopite,illite,and vermiculite composite containing Al-O tetrahedrons than in kaolinite containing only Al-O *** Oxisols derived from basalt with different ages were selected for similar ***27Al MAS-NMR spectra of the Oxisols showed that the 0.01-million-year(Ma)Oxisol contained both octahedral and tetrahedral Al,while the 1.33-Ma Oxisol contained only Al-O *** contents of both exchan

关键词： Al-O octahedrons Al-O tetrahedrons aluminum release exchangeable Al phyllosilicate minerals soil acidification

脊柱内镜杂交技术与单轴脊柱内镜治疗双侧症状腰椎管狭窄症的减压效果对比

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中国组织工程研究 2025年第3期29卷 517-523页

作者：郭松李新华晏美俊刘彦斌刘中李克威刘鹏程张备挺付强上海交通大学附属第一人民医院脊柱外科上海市200080

背景:单轴脊柱内镜下腰椎管减压是一种新型的治疗腰椎管狭窄症的微创手术方式,但是该技术学习曲线陡峭,对手术设备和器械要求较高,限制其临床应用。前期作者团队将脊柱内镜作为监视内镜结合单侧双通道内镜技术率先提出脊柱内镜杂交技术... 详细信息

背景:单轴脊柱内镜下腰椎管减压是一种新型的治疗腰椎管狭窄症的微创手术方式,但是该技术学习曲线陡峭,对手术设备和器械要求较高,限制其临床应用。前期作者团队将脊柱内镜作为监视内镜结合单侧双通道内镜技术率先提出脊柱内镜杂交技术,实现同轴内镜下操作与双手分离操作。目的:比较脊柱内镜杂交技术及单轴脊柱内镜技术治疗双侧症状腰椎管狭窄症的临床疗效。方法:回顾性分析2020年8月至2022年8月在上海交通大学附属第一人民医院接受治疗的双侧下肢疼痛症状腰椎管狭窄症患者90例,其中A组(脊柱内镜杂交技术)44例,B组(单轴脊柱内镜术)46例。术中观察神经减压情况;记录两组患者手术时间、住院时间及花费;记录并对比术前及术后3 d、3个月、6个月腰痛及双侧下肢放射痛目测类比评分、生活质量Oswestry功能障碍指数及改良Macnab优良率。结果与结论:①A组手术时间明显短于B组(P0.05);A组术后3,6个月症状轻微侧目测类比评分明显低于B组(P0.05);术后3,6个月Oswestry功能障碍指数组间比较,A组明显低于B组(P<0.05);④术后3个月A组Macnab优良率明显高于B组(95%,78%,P<0.05);⑤提示脊柱内镜杂交技术是一种新型的脊柱内镜技术,具有微创手术创伤小、恢复快等优势,采用该技术行单侧入路双侧减压治疗双侧症状腰椎管狭窄症的疗效优于单轴脊柱内镜技术,同时具有开放手术器械操作灵活性好、减压效率高的优势。

关键词：脊柱内镜杂交技术单轴脊柱内镜技术腰椎管狭窄症双侧症状减压

Thermal Stability and Degeneration Behavior of Solar Selective Absorber Based on WTi-Al_(2)O_(3)Cermet

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Journal of Wuhan University of Technology(Materials Science) 2024年第6期39卷 1555-1564页

作者： WANG Xiaobo FANG Wei MA Yuchao CHENG Xudong li kewei Department of Physics and Electronic Engineering Jinzhong UniversityJinzhong 030619China College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China State Key Laboratory of Advanced Technology for Materials Synthesis and Progressing Wuhan University of TechnologyWuhan 430070China

A WTi-Al_(2)O_(3)cermet-based solar selective absorber was prepared to investigate the atomic diffusion induced spectral selectivity *** as-deposited coating exhibits superior absorptance(0.934)and low thermal emittance(0.098),as well as excellent thermal stability with a selectivity of 0.900/0.07 even after annealing at 923 K for 400 h in Ar ***,the multilayer coating failed after being subjected to annealing at 923 K for 400 h in an air environment,as indicated by a decrease in solar absorptance to 0.912 and an increase in thermal emittance to *** microstructure characterizations reveal that the annealed coating exhibits a columnar morphology along the vertical direction of the *** presence of abundant grain boundaries in the multilayer coating promotes the outward diffusion of Cr and Mn atoms in the stainless-steel *** Mn atoms,in particular,possess the capability to migrate towards the surface of the coating and undergo an oxidation reaction with oxygen,facilitating the formation of a thick Mn_(2)O_(3)*** roughness of the coating surface was significantly increased in this case,adversely affecting solar absorptance due to amplified sunlight *** addition,the rocketing of thermal emittance is attributed to the destabilization of W infrared reflective layer during the *** findings highlight the importance of considering the outward diffusion of Mn and Cr elements in the stainless-steel substrate when optimizing solar selective absorbers.

关键词： solar selective absorber thermal stability spectral selectivity optical properties

外泌体miRNA差异表达可作为诊断慢性心力衰竭合并高尿酸血症患者新型分子标志物及靶基因功能分析

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南方医科大学学报 2025年第1期45卷 43-51页

作者：陈志亮杨永刚黄霞成彦瞿媛衡琪琪符羽佳李可薇顾宁南京中医药大学附属南京中医院心血管病科江苏南京210022 南京中医药大学附属南京中医院检验科江苏南京210022 南京中医药大学附属南京中医院药学部江苏南京210022 南京中医药大学附属南京中医院急诊科江苏南京210022 南京中医药大学江苏南京210023

目的分析慢性心力衰竭(CHF)合并高尿酸血症(HUA)患者血清外泌体miRNA的差异表达,探讨其作为CHF合并HUA新型诊断分子标志物的可能性,并对差异miRNA进行靶基因功能分析,分析作用靶点。方法以2020年9月~2023年9月南京中医药大学附属南京中... 详细信息

目的分析慢性心力衰竭(CHF)合并高尿酸血症(HUA)患者血清外泌体miRNA的差异表达,探讨其作为CHF合并HUA新型诊断分子标志物的可能性,并对差异miRNA进行靶基因功能分析,分析作用靶点。方法以2020年9月~2023年9月南京中医药大学附属南京中医院心血管病科收治的CHF合并HUA患者为观察组(n=30),选择同期健康志愿者为对照组(n=30)。两组各选取6例样本,采用高通量测序分析血清外泌体中的差异表达miRNA,采用RT-PCR检测对未作高通量测序的观察组和对照组样本(n=24)进行验证,使用R软件进行GO、KEGG富集分析,预测差异表达miRNA的作用靶点,并通过动物实验验证临床筛查的差异miRNA。结果高通量测序分析显示,观察组患者共检测到42个差异表达的miRNA(18个上调,24个下调),其中miR-27a-5p上调(P<0.001),miR-139-3p下调(P<0.001)。RT-PCR检测显示,观察组患者血清外泌体中miR-27a-5p表达量上调(P=0.004)、miR-139-3p表达量下调(P=0.005);ROC曲线下面积(AUC)分析发现,miR-27a-5p、miR-139-3p预测CHF合并HUA发病的AUC分别是0.708(95%CI:0.562-0.855)和0.734(95%CI:0.593-0.876),两者联合预测CHF与HUA发病的AUC为0.899(95%CI:0.812-0.987)。对差异基因进行GO富集分析发现,细胞自噬是富集程度最高的靶点;KEGG功能注释显示,激活AMPK-mTOR信号通路可能是差异表达的miR-27a-5p和miR-139-3p作用靶点之一。进一步动物实验得到了相同的验证。结论血清外泌体中miR-27a-5p上调和miR-139-3p下调可作为精准诊断CHF合并HUA的新型分子标志物,激活AMPK-mTOR信号通路后促进心肌细胞的自噬反应可能是差异表达的miR-27a-5p、miR-139-3p的作用靶点之一。

关键词：慢性心力衰竭高尿酸血症外泌体微小RNA AMPK mTOR 自噬

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Synthesis and formation mechanism of HfB_(2) ultrafine powders with low oxygen via flocculating settling assisted process and carbo/borothermal reduction

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Journal of Materials Science & Technology 2023年第33期164卷 229-239页

作者： Zhen Wang Yuan Cheng kewei li Tianxu Wang Mengen Hu Chunxue Zheng Xinyang li Zhulin Huang Xiaoye Hu Yue li Xinghong Zhang University of Science and Technology of China Hefei 230026China Key Laboratory of Materials Physics and Anhui Key Laboratory of Nanomaterials and Nanotechnology Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China Anhui University Hefei 230039China Harbin Institute of Technology Harbin 150001China

In this study,ultrafine HfB_(2) powders with low oxygen were synthesized by a flocculating settling process which yielded ceramic precursors and subsequent carbo/borothermal reduction of the *** liquid phase precursor method can achieve uniform mixing of components at the molecular level through multiple complexation reactions,and then realize the carbo/borothermal reduction reaction at a lower temperature to obtain ultrapure HfB2 *** as-resulted quasi-spherical HfB2 powders under the optimum conditions(atomic molar ratio M:B:C=1:2.8:10)calcined at 1500°C for 1 h have an average particle size of 205 nm and an oxygen content of 0.097 wt.%.Detailed analysis of the phase evolution of precursors shows that the formation of HfB2 particles is a mass diffusion mode from the external to internal HfO_(2)*** reveal that below 1300°C,HfC is not an intermediate product of HfB2 powder during the transition of ***,HfC was formed as a by-product at high temperatures in the carbo/borothermal reduction *** proposed formation mechanism of HfB_(2) is completely different from the traditional two-step transformation *** the sintering of the ultrafine powders,the HfB_(2) ceramics show a relative density of 96.1%and superior mechanical properties compared to other ***,by simply replacing the initial metal source,chlorinated group IV and V transitional metals(Ti,Zr,Ta,Nb)can also convert into high-purity and ultrafine *** work shows that flocculating settling assisted carbo/borothermal reduction has potential in lot size production of various high-purity and ultrafine boride powders.

关键词： Boride powders Flocculating settling Low oxygen content High-purity

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晶种法合成硼化铪粉体及其生长机理研究

航空制造技术 2025年第03期68卷 84-91页

作者：王振胡晨光李可为胡梦恩张瀚文黄竹林胡小晔中国科学院合肥物质科学研究院固体物理研究所

硼化铪（HfB2）超高温陶瓷因其高熔点、高抗氧化性和优异的耐腐蚀性成为热防护领域的最佳候选材料之一，而研制粒径可控的陶瓷粉体对其应用至关重要。以氧化铪（HfO2）、氧化硼（B2O3）和活性碳（C）为原料，通过晶种辅助的硼/碳热还原... 详细信息

硼化铪（HfB2）超高温陶瓷因其高熔点、高抗氧化性和优异的耐腐蚀性成为热防护领域的最佳候选材料之一，而研制粒径可控的陶瓷粉体对其应用至关重要。以氧化铪（HfO2）、氧化硼（B2O3）和活性碳（C）为原料，通过晶种辅助的硼/碳热还原法合成了高纯HfB2陶瓷粉体，研究了晶种粒径对陶瓷粉体粒径的影响规律，探究了晶种法合成HfB2粉体的生长机制。通过X射线衍射分析粉体物相、扫描电子显微镜观察粉体形貌，并测定粉体中C、O杂质的含量。结果表明，晶种辅助的硼/碳热还原反应合成HfB2粉体的最佳反应温度约为1500℃，保温1 h即可获得纯相HfB2。通过调控初始晶种粒径，制备的HfB2陶瓷粉体平均粒径在1.08～2.33μm之间，且粉体粒径随晶种粒径的增大而增大。激光粒度分析表明，添加晶种大幅提高了陶瓷粉体的分散性且促进了粒径的窄分布。此外，试验确定了HfB2陶瓷粉体的生长过程分为两个阶段：首先晶种HfB2表面被HfO2晶粒包覆，HfO2晶粒表层形成较小的HfB2晶粒；再通过碳和硼的传质由外到内实现HfO2到HfB2的转化。

关键词：硼化铪(HfB2) 晶种硼/碳热还原粒径陶瓷粉体形貌

Hand in Hand—Kids Helping Kids

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Women of China 1994年第10期 24-25页

作者： FENG kewei li li

This year, on the eve of the June I International Children’s Day, the Central Committee of the Chinese Communist Youth League and the China Young Pioneers Working Committee invited 100 pairs of friends to Beijing to ... 详细信息

关键词： In Kids Helping Kids Hand in Hand