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儿童持续思维问卷的中文修订及其信效度检验

中国临床心理学杂志 2024年第3期32卷 601-605页

作者：徐婷张宇轩黄澜李海江上海师范大学心理学院上海200234 上海师范大学教育部“教育大数据与教育决策”实验室上海200234

目的:修订儿童持续思维问卷(perseverative thinking questionnaire-children,PTQ-C),检验其在中国儿童和青少年中的信效度。方法:对3628名儿童和青少年施测中文版PTQ-C,选取反刍思维、焦虑、抑郁量表及快乐指数作为效标,并对其中417名... 详细信息

目的:修订儿童持续思维问卷(perseverative thinking questionnaire-children,PTQ-C),检验其在中国儿童和青少年中的信效度。方法:对3628名儿童和青少年施测中文版PTQ-C,选取反刍思维、焦虑、抑郁量表及快乐指数作为效标,并对其中417名被试进行了3个月后的重测。结果:探索性因素分析和验证性因素分析均支持中文版PTQ-C的单因素模型;问卷总分与反刍思维、焦虑、抑郁均呈显著正相关,与快乐指数呈显著负相关;问卷的内部一致性系数为0.959,分半信度为0.929,三个月后的重测信度为0.610;中文版PTQ-C在青少年样本中跨性别和跨年级的形态等值性、弱等值性与强等值性均成立。结论:中文版PTQ-C具有良好的信效度和测量等值性,可以作为中国儿童和青少年重复性消极思维的有效测量工具。

关键词：重复性消极思维信度效度测量等值性

Lanthanum Prevents Salt Stress-induced Programmed Cell Death in Rice Root Tip Cells by Controlling Early Induction Events

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Journal of Integrative Plant Biology 2007年第7期49卷 1024-1031页

作者： Jian-You li Ai-liang jiang hai-Yan Chen Ying Wang Wei Zhang Department of Biochemistry and Molecular Biology College of Life Science Nanjing Agricultural University Nanjing 210095 China

In a previous study, a salt stress-induced programmed cell death （PCD） model was established in rice root tip cells. Here, by using Wuyunjing 8th rice seedlings, the effects of lanthanum on salt stress-induced PCD early events were studied. The results indicated that low concentrations （10 μmol/L）, but not high concentrations （100 μmol/L） of LaCl3 could effectively prevent salt stress-induced PCD. Further study demonstrated that in the early stages of salt-induced PCD process, 10 μmol/L of La^3＋ could prevent the increase of cytoplasmic calcium levels, inhibit reactive oxygen species （ROS） production, and enhance the ROS-scavenging enzyme activities such as superoxide dismutases （SOD） and ascorbate peroxidase （APX）. Imidazole （20 mmol/L）, the inhibitor of nicotinamide adenine dinucleotide phosphate-oxidase （NADPH oxidase）, could alleviate the occurrence of PCD obviously, and such alleviation could be enhanced by the addition of La^3＋, indicating the involvement of NADPH oxidase in the salt stress-induced PCD process. Taken together, lanthanum could prevent salt stress-induced PCD occurrence in the rice root tip cells by blocking the calcium influx under stress, which was followed by inhibiting calcium-dependent NADPH oxidase activity to prevent O2^·- production and, enhancing the cytosolic antioxidative enzyme activities to scavenge the reactive oxygen species.

关键词： Ca^2+ Oryza sativa programmed cell death reactive oxygen species salt stress.

Synthesis of a novel multivalent galactoside with high hepatocyte targeting for gene delivery

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Chinese Chemical Letters 2008年第2期19卷 127-129页

作者： Qing lin jiang li hai Lei Chen Jiao Lu Zhi Rong Zhang Yong Wu Key Laboratory of Drug Targeting of Education Ministry West China School of Pharmacy Sichuan University Chengdu 610041 China

A novel bifunctional glycolipid which carded a cluster of thiogalactosides as the hepatocyte targeting ligand for gene delivery was prepared. Hexa-antennary alcohol 1 was used as the core scaffold to attach a cholesterol molecule by a poly（ethylene glycol） chain, while its remaining branches were linked with five acetylgalactosides, which would be deacetylated later to produce pentaantennary galactoside. liposome containing the galactoside showed high affinity and transfection activity in hepatoma cells HepG2.

关键词： Clustered glycosides Targeting Galactosylated ligand Hepatocyte Gene delivery

Pharmacokinetics and tissue distribution of intraperitoneal 5-fluorouracil with a novel carrier solution in rats

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World Journal of Gastroenterology 2008年第14期14卷 2179-2186页

作者： Zhi-Gang Wei Guo-Xin li Xiang-Cheng Huang li Zhen jiang Yu hai-Jun Deng Shan-Hua Qing Ce Zhang Department of General Surgery Nanfang Hospital Southern Medical University Guangzhou 510515 Guangdong Province China

AIM: To compare the pharmacokinetics and tissue distribution of 5-fluorouracil administered intraperitoneally with two isotonic carrier solutions: HAES-steri (neotype 6% hydroxyethyl starch), a novel carrier solution with middle molecular weight and physiologic saline (0.9% sodium chloride solution), a traditional carrier solution for intraperitoneal chemotherapy, in rats. METHODS: A total of 60 Sprague Dawley rats were randomized into groups according to the carrier solution administered. Each group was further randomized according to the intraperitoneal dwell period (1, 3, 6, 12, 18 and 24 h). At the end of the procedure the rats were killed, the peritoneal fluid was withdrawn completely and quantitated. Drug concentrations in peritoneal fluid, plasma, and tissues were determined by high- performance liquid chromatography. RESULTS: The mean volumes remaining in the peritoneal cavity were significantly higher with HAES- steri than those with physiologic saline at 1, 6, 12, 18, and 24 h (P = 0.047, 0.009, 0.005, 0.005 and 0.005 respectively, the percentages of remaining peritoneal fluid volume were 89.9 ± 5.6 vs 83.4 ± 4.9, 79.9 ± 2.8 vs 56.2 ± 15.7, 46.8 ± 5.5 vs 24.7 ± 9.7, 23.0 ± 2.8 vs 0.0 ± 0.0 and 4.2 ± 1.7 vs 0.0 ± 0.0 respectively). Mean concentrations in peritoneal fluid were significantly higher with HAES-steri than those with physiologic saline at 3, 12 and 18 h (P = 0.009, 0.009 and 0.005 respectively, the concentrations were 139.2768 ± 28.2317 mg/L vs mg/L, 11.5427 ± 3.0976 mg/L vs 0.0000 ± 0.0000 mg/L and 4.7724 ± 1.0936 mg/L vs 0.0000 ± 0.0000 mg/L respectively). Mean plasma 5-fluorouracil concentrations in portal vein were significantly higher with HAES-steri at 3, 12, 18 and 24 h (P = 0.009, 0.034, 0.005 and 0.019 respectively, the concentrations were 3.3572 ± 0.8128 mg/L vs 0.8794 ± 0.2394 mg/L, 0.6203 ± 0.9935 mg/L vs 0.0112 ± 0.0250 mg/L, 0.3725 ± 0.3871 mg/L vs 0.0000 ± 0.0000 mg/L, and 0.2469 ± 0.1457 mg/L vs 0.0000 ± 0.0000 mg/L respectively),

关键词： Carrier solutions Intraperitoneal chemo- therapy 5-fluorouracil Pharmacokinetics Tissue distribution

Promoted hydrogenation of CO2 to methanol over single-atom Cu sites with Na+-decorated microenvironment

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National Science Review 2024年第6期11卷 264-272页

作者： li-li ling Xinyu Guan Xiaoshuo liu Xiao-Mei Lei Zhongyuan lin hai-Long jiang Hefei National Research Center for Physical Sciences at the Microscale Department of Chemistry University of Science and Technology of China School of Energy and Power Engineering North China Electric Power University School of Energy and Environment Southeast University

Although single-atom Cu sites exhibit high efficiency in CO2hydrogenation to methanol,they are prone to forming Cu nanoparticles due to reduction and aggregation under reaction conditions,especially at high ***,single-atom Cu sites stabilized by adjacent Na+ions have been successfully constructed within a metal-organic framework（MOF）-based catalyst,namely *** is found that the electrostatic interaction between the Na+and Hδ-species plays a pivotal role in upholding the atomic dispersion of Cu in MOF-808-NaCu during CO2hydrogenation,even at temperatures of up to 275℃.This exceptional stabilization effect endows the catalyst with excellent activity(306 g·kgcat-1·h-1),high selectivity to methanol（93%） and long-term stability at elevated reaction temperatures,far surpassing the counterpart in the absence of Na+（denoted as MOF-808-Cu）.This work develops an effective strategy for the fabrication of stable single-atom sites for advanced catalysis by creating an alkali-decorated microenvironment in close proximity.

关键词： single-atom sites metal–organic framework CO2 hydrogenation heterogeneous catalysis alkali-metal decoration

Rhyscotus subrisus li&jiang,***.,representing a new record family Rhyscotidae from China(Isopoda:Oniscidea)

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Zoological Systematics 2024年第2期49卷 181-183页

作者： Chonghui Yao Chao jiang Weichun li College of Agronomy Jiangxi Agricultural UniversityNanchang 330045China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs National Resource Center for Chinese MateriaMedicaChina Academy of Chinese Medical SciencesBeijing 100700China

The family Rhyscotidae Budde-Lund,1904 contains two genera:Rhyscotoides Schmalfuss&Ferrara,1978 and Rhyscotus Budde-Lund,*** date,twenty-one species within the family are known,occurring in the subtropic and tropic regions(Schmalfuss,2003;Schmidt,2003;Boyko et al.,2022).The members of the family can be recognized by the cephalon with a strongly inflated frons,the antennae with two-jointed flagellum,the maxillae are almost semicircular,the maxillipeds have short palpus and endite,and pleopod exopodites without pseudotracheae(Schmalfuss&Ferrara,1978).Before this study,the members of Rhyscotidae were unknown in *** present research describes a new species of the genus Rhyscotus from hainan Island,representing a new record of the family Rhyscotidae from China.

关键词： record family

Experimental Study on Engineering Behavior of Solidified Soil for Scour Repair and Protection

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China Ocean Engineering 2024年第4期38卷 625-635页

作者： WU Xiao-ni li Ru-yu SHU Jian TANG Chao CHEN Jin-jian WANG Hui-li jiang hai-li WANG Xiao State Key Laboratory of Ocean Engineering Department of Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Shanghai Road and Bridge Group Co. Ltd.Shanghai 200433China Shanghai Engineering Research Center of Urban Infrastructure Renewal Shanghai 200032China jiangsu Kunze Technology Co. Ltd.Nanjing 210000China

A new scour countermeasure using solidified slurry for offshore foundation has been proposed *** solidified slurry is pumped to seabed area around foundation for scour protection or pumped into the developed scour holes for scour repair as the fluidized material solidifies *** the pumping operation and solidification,the engineering behaviors of solidified slurry require to be considered synthetically for the reliable application in scour repair and protection of ocean engineering such as the pumpability related flow value,flow diffusion behavior related rheological property,anti-scour performance related retention rate in solidification and bearing capacity related strength property after *** this study,a series of laboratory tests are conducted to investigate the effects of mix proportion(initial water content and binder content)on the flow value,rheological properties,density,retention rate of solidified slurry and unconfined compressive strength(UCS).The results reveal that the flow value increases with the water content and decreases with the binder *** the solidified slurry exhibits Bingham plastic behavior when the shear rate is larger than 5 s^(-1).The Bingham model has been employed to fit the rheology test results,and empirical formulas for obtaining the density,yield stress and viscosity are established,providing scientific support for the numerical assessment of flow and diffusion of solidified *** rate of solidified slurry decreases with the water flow velocity and flow value,which means the pumpability of solidified slurry is contrary to anti-scour *** unconfined compressive strength after solidification reduces as the water content increases and binder content decreases.A design and application procedure of solidified soil for scour repair and protection is also proposed for engineering reference.

关键词： scour repair and protection solidified soil pumpability strength flow properties anti-scour performance

Safety and efficacy of laser and cold knife urethrotomy for urethral stricture

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Chinese Medical Journal 2010年第12期123卷 1589-1595页

作者： JIN Yao li Hong jiang li-hai WANG li WANG Kun-jie Department of Urology West China Hospital Sichuan University Chengdu Sichuan 610041 China Chinese Evidence-based Medicine Centre West China Hospital Sichuan University Chengdu Sichuan 610041 China

Background Endoscopic treatment for urethral stricture, including cold knife and laser, poses a major challenge to clinical practice. Both the benefits and drawbacks of these two treatments remain controversial. This article aimed to compare the efficacy and safety of laser and cold knife urethrotomy for urethral stricture. Methods We searched PubMed （1966-2009）, Embase （1980-2009）, Cochrane Central Register of Controlled Trials （CCRCT, 2009 No.l） and Chinese Biomedical literature Database （CBM） for laser and cold knife urethrotomy as treatment for male urethral stenosis, looking in the English literatures. Two reviewers independently screened the literatures and extracted information. Chi-square test was used for statistical analysis with SPSS15.0. Results A total of 44 articles, including of 3230 cases was retrieved. Success rate of patients treated with laser was 74.9% compared with 68.5% for cold knife, with very similar clinical results despite a statistically significant difference （P=-0.004）. The trend in success rate at a different follow-up time was similar between the two groups. No significant difference in success rate was found between the groups of repeat operation for recurrence cases, first P=0.090 and second P=0.459. The shorter the stricture length was （〈1 cm）, the higher the success rate was （P 〈0.0001）. No significant difference in success rate between the laser and cold knife groups was found in neither bulbar nor membranous urethra, bulbar P=0.660 and membranous P=0.477. The rates of urinary incontinence, urinary extravasation, and urinary tract infection showed no significant difference （P=-0.259, P=0.938, P=-0.653, respectively）. Conclusions Success rates for laser and cold knife were very similar despite being statistically different, with the groups having a similar trend in success rates at different follow-up time. Stricture location and history of endoscopic intervention did impact treatment outcome but was not significantly different. T

关键词： urethral stricture urologic surgical procedures, treatment outcome

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基于集群的并行有限元分析研究

计算力学学报 2007年第1期24卷 117-123页

作者：李海江大连海事大学道路与桥梁工程研究所辽宁大连116026

利用面向对象的方法实现了基于集群的并行有限元分析。首先介绍构建高性能计算集群的系统分析新方法,并针对建成集群系统的特点,对并行消息传递库MPI进行了并行语义分析,进而对其主要的实现函数进行面向对象的重构而建立起OO消息传递库... 详细信息

利用面向对象的方法实现了基于集群的并行有限元分析。首先介绍构建高性能计算集群的系统分析新方法,并针对建成集群系统的特点,对并行消息传递库MPI进行了并行语义分析,进而对其主要的实现函数进行面向对象的重构而建立起OO消息传递库,以此为基础分别利用两种不同的策略实现了面向对象的并行有限元分析(OOParaFEA:Object-Oriented Parallel FEA),一种是通过对传统的基于域分解方法的并行PCG算法进行改造而在集群平台实现,另一种是对已有的基于子结构方法的串行有限元分析程序加以扩展,加入系统方程组并行求解器而达到有限元分析并行化的目的。多个分析算例表明,基于集群进行面向对象的并行有限元分析可以有效提高计算效率,为进一步的网络化CAD/CAE研究奠定良好基础。

关键词：集群高性能计算并行有限元面向对象