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不确定非线性系统快速终端滑模控制

自动化应用 2024年第6期65卷 1-5,8页

作者：江道根沈甦李家豪宁波城市职业技术学院浙江宁波315100 宁波技师学院浙江宁波315000

针对界未知的非匹配不确定非线性系统轨迹快速跟踪控制,设计非线性干扰观测器(NDO)的反演自适应终端滑模控算法。首先设计子系统干扰观测器来确定界未知非匹配项补偿量,并结合子系统的Lyapunov函数求出反演控制中虚拟控制律,并运用指令... 详细信息

针对界未知的非匹配不确定非线性系统轨迹快速跟踪控制,设计非线性干扰观测器(NDO)的反演自适应终端滑模控算法。首先设计子系统干扰观测器来确定界未知非匹配项补偿量,并结合子系统的Lyapunov函数求出反演控制中虚拟控制律,并运用指令滤波器解决虚拟项求导所带来的微分膨胀缺陷;再设计系统的非奇异快速终端滑模面并给出建模误差不确定性的自适应律,继而求出系统总控制律以确保总闭环系统有限时间全局渐近稳定;最后机器人动力学仿真案例表明,所设计的控制器能实现对指定轨迹的快速稳定跟踪,控制量光滑弱抖振,并对非匹配干扰具有较强的鲁棒性。

关键词：不确定非线性系统快速终端滑模控制机器人动力学

Comprehensive Approach to Assessment of liver Viability During Normothermic Machine Perfusion

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Journal of Clinical and Translational Hepatology 2023年第2期11卷 466-479页

作者： jiahao li Haoyang Lu Jian Zhang Yixuan li Qiang Zhao Organ Transplant Center The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina

liver transplantation is the most effective treatment of advanced liver disease,and the use of extended criteria donor organs has broadened the source of available *** normothermic machine perfusion(NMP)has become a useful tool in liver transplantation,there are no consistent criteria that can be used to evaluate the viability of livers during *** review summarizes the criteria,indicators,and methods used to evaluate liver viability during *** shape,appearance,and hemodynamics of the liver can be analyzed at a macroscopic level,while markers of liver injury,indicators of liver and bile duct function,and other relevant indicators can be evaluated by biochemical *** liver can also be assessed by tissue biopsy at the microscopic *** methods for assessment of liver viability are *** limitations of evaluating liver viability during NMP are discussed and suggestions for future clinical practice are provided.

关键词： Normothermic machine perfusion liver viability Criteria

融合BERT-WWM与注意力机制的电力设备缺陷实体识别研究

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电力学报 2024年第2期39卷 126-135页

作者：李嘉皓熊威龚康王凌云三峡大学电力与新能源学院湖北宜昌443000 国网宜昌供电公司湖北宜昌443000

针对电力设备运行和维护中所产生的大量碎片化、非系统性以及相关性不足设备缺陷文本,提出了一种电力设备缺陷文本识别模型。使用基于全词掩码的预训练模型(bidirectional encoder representation from transform-ers,BERT)替换基于随... 详细信息

针对电力设备运行和维护中所产生的大量碎片化、非系统性以及相关性不足设备缺陷文本,提出了一种电力设备缺陷文本识别模型。使用基于全词掩码的预训练模型(bidirectional encoder representation from transform-ers,BERT)替换基于随机掩码的BERT模型,提高了对电力词汇的理解力。使用双向长短期记忆网络(bidirection-al long short-term memory,BiLSTM)提高了模型捕获上下文信息的能力,并提高了模型的鲁棒性,引入注意力机制(attention)可以更好地捕获电力设备缺陷实体之间的复杂依赖关系,从而进一步提升模型的表现。实验结果显示,该模型准确率、召回率、F1值分别为96.26%、96.94%、96.60%,在地点、缺陷内容和设备三种实体上的F1值均优于其他模型。

关键词：电力设备缺陷文本命名实体识别 BERT 双向长短期记忆网络注意力机制条件随机场

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Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression-and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner

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Acta Pharmaceutica Sinica B 2023年第12期13卷 4801-4822页

作者： Kaikai Zhang lijian Chen Jianzheng Yang Jiali liu jiahao li Yi liu Xiuwen li Long Chen Clare Hsu jiahao Zeng Xiaoli Xie Qi Wang Guangzhou Key Laboratory of Forensic Multi-Omics for Precision Identification School of Forensic MedicineSouthern Medical UniversityGuangzhou 510515China Department of Toxicology School of Public HealthSouthern Medical University(Guangdong Provincial Key Laboratory of Tropical Disease Research)Guangzhou 510515China

Methamphetamine(Meth)abuse can cause serious mental disorders,including anxiety and *** gut microbiota is a crucial contributor to maintaining host mental ***,we aim to investigate if microbiota participate in Meth-induced mental disorders,and the potential mechanisms ***,15 mg/kg Meth resulted in anxiety-and depression-like behaviors of mice successfully and suppressed the Sigma-1 receptor(SIGMAR1)/BDNF/TRKB pathway in the ***-while,Meth impaired gut homeostasis by arousing the Toll-like receptor 4(TLR4)-related colonic inflammation,disturbing the gut microbiome and reducing the microbiota-derived short-chain fatty acids(SCFAs).Moreover,fecal microbiota from Meth-administrated mice mediated the colonic inflam-mation and reproduced anxiety-and depression-like behaviors in ***,SCFAs supple-mentation optimized Meth-induced microbial dysbiosis,ameliorated colonic inflammation,and repressed anxiety-and depression-like ***,Sigmarl knockout(Sigmar1^(-/-))repressed the BDNF/TRKB pathway and produced similar behavioral phenotypes with Meth exposure,and elim-inated the anti-anxiety and-depression effects of *** activation of SIGMAR1 with fluvoxamine attenuated Meth-induced anxiety-and depression-like *** findings indicated that gut microbiota-derived SCFAs could optimize gut homeostasis,and ameliorate Meth-induced mental disorders in a SIGMAR1-dependent *** study confirms the crucial role of microbiota in Methrelated mental disorders and provides a potential preemptive therapy.

关键词： Methamphetamine Gut microbiota Short-chain fatty acids Sigma-1 receptor Mental disorders Colonic inflammation Intestinal barrier Gut-brain axis

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铁自噬介导铁死亡在脓毒症中的研究进展

中国急救医学 2024年第4期44卷 361-365页

作者：王勉康印东李佛荣李家豪蒋星明常德辉甘肃中医药大学第一临床医学院甘肃兰州730050 解放军联勤保障部队第九四〇医院泌尿外科甘肃兰州730050 甘肃省干细胞与基因药物重点实验室甘肃兰州730030 西北民族大学医学部甘肃兰州730050

铁自噬介导铁死亡在脓毒症及其相关器官功能障碍中具有调节作用。铁自噬通过特定载体核受体激活因子4(NCOA4)介导,将细胞内的铁蛋白转移到自噬溶酶体中进行降解并释放出游离铁,以满足多种铁依赖的生理过程需要。铁自噬是构成铁死亡机制... 详细信息

铁自噬介导铁死亡在脓毒症及其相关器官功能障碍中具有调节作用。铁自噬通过特定载体核受体激活因子4(NCOA4)介导,将细胞内的铁蛋白转移到自噬溶酶体中进行降解并释放出游离铁,以满足多种铁依赖的生理过程需要。铁自噬是构成铁死亡机制的重要组成部分。本文综述铁自噬与铁死亡机制在脓毒症治疗中的研究进展,为深入了解其发病机制和脓毒症相关器官功能障碍提供新的治疗方向。

关键词：铁自噬铁死亡核受体共激活因子4 脓毒症心肌损伤急性肺损伤急性肾损伤

改进YOLOv5的探地雷达常见地下管线识别

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地球物理学报 2024年第9期67卷 3588-3604页

作者：王惠琴罗佳何永强曹明华高大庆李佳豪兰州理工大学计算机与通信学院兰州730050 西北民族大学土木工程学院兰州730030

针对当前探地雷达(Ground Penetrating Radar,GPR)图像识别准确率低,且小目标识别困难等问题,本文将YOLOv5(You Only Look Once)和ConvNeXt网络相结合,提出一种适用于GPR图像的常见地下管线识别网络ConvNeXt-YOLOv5,显著提高了雷达图像... 详细信息

针对当前探地雷达(Ground Penetrating Radar,GPR)图像识别准确率低,且小目标识别困难等问题,本文将YOLOv5(You Only Look Once)和ConvNeXt网络相结合,提出一种适用于GPR图像的常见地下管线识别网络ConvNeXt-YOLOv5,显著提高了雷达图像中小目标的识别精度.同时,为了解决因地下管线原始信息不足而导致的模型训练精度低的问题,使用实测GPR图像、时域有限差分法(Finite-Difference Time-Domain,FDTD)与混类增强算法Mixup模拟图像构建数据集.然后,在此数据集上验证了本文所提方法对常见地下管线的识别效果,并用识别后的二维GPR B-scan图像还原出地下管线的三维图像.实验结果表明,对镀锌输水钢管、PVC管、电缆线和含水塑料瓶等常见地下管线进行识别时,ConvNeXt-YOLOv5表现出优良的识别性能.尤其是对PVC管的识别精度提升明显.与YOLOv4、YOLOv5、YOLOv7和Faster R-CNN模型相比,其平均精度均值分别提高了3.83%、2.82%、1.9%和3.72%.同时,三维探地雷达图像更直观的还原了地下管线信息.

关键词：探地雷达地下管线深度学习 ConvNeXt 三维显示

基于小批量NTAG全自动读写设备的应用设计

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信息与电脑 2024年第12期36卷 105-107页

作者：赖晓杰李家豪黄海燕广州城市理工学院计算机工程学院

小批量近场通信标签（Near Field Communication Tag,NTAG）全自动读写设备利用由C#技术开发的上位机操作Excel文件进行数据处理，并驱动通用串行总线（Universal Serial BUS,USB）与下位机通信。机械部分根据料盘的结构特点设计了一种... 详细信息

小批量近场通信标签（Near Field Communication Tag,NTAG）全自动读写设备利用由C#技术开发的上位机操作Excel文件进行数据处理，并驱动通用串行总线（Universal Serial BUS,USB）与下位机通信。机械部分根据料盘的结构特点设计了一种自适应卡盘，传动部分根据NTAG的材料特点采用了限位开关与步进电机配合的方式，实现了精准定位。下位机以意法半导体系列单片机为核心，驱动电机芯片与射频识别传感器，实现了电机的变速控制与自动读写。

关键词： NTAG 自动读写 C#技术

Integrated transcriptomics and metabolomics analyses provide insights into cold stress response in wheat

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The Crop Journal 2019年第6期7卷 857-866页

作者： Yong Zhao Meng Zhou Ke Xu jiahao li Shanshan li Shuhua Zhang Xueju Yang Huabei Key Laboratory of Crop Germplasm Hebei Agricultural UniversityBaoding 071000HebeiChina College of life Sciences Hebei UniversityBaoding 071000HebeiChina

Cold tolerance of crop plants influences survival and productivity under low-temperature conditions. Elucidation of molecular mechanisms underlying low temperature tolerance could be helpful in breeding. In this study, we used integrated transcriptomics and metabolomics analyses to investigate changes in gene/metabolite activity in a winter-hardy wheat cultivar of(cv. Jing 411) when subjected to sold stress. The 223 metabolites mainly enriched during cold acclimation included carbohydrates, flavonoids, and amino *** common metabolites had altered abundance following freezing treatment;six increased and two decreased. Transcriptome analysis revealed that 29,066 genes were differentially expressed in wheat crowns after cold acclimation compared to the nonacclimated control. Among them, 745 genes were up-regulated following freezing treatment, suggesting substantial change in expression of a large quantity of genes upon cold acclimation and freezing treatment, which impacts on the modified *** analysis of gene expression and metabolite profiles revealed that the abscisic acid(ABA)/jasmonic acid(JA) phytohormone signaling and proline biosynthesis pathways were significantly modulated under cold acclimation and freezing treatments. Our results indicated that low-temperature stress induced substantial changes in both transcriptomes and metabolomes. Critical pathways associated with ABA/JA signaling and proline biosynthesis played important roles in regulating cold tolerance in wheat.

关键词： Cold tolerance Transcriptome Metabolome Abscisic acid Jasmonic acid Signaling pathways

The constraints of strain partitioning and geochronology in Luonan-Luanchuan tectonic belts on Qinling orogenic belt

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Science China Earth Sciences 2009年第3期52卷 300-312页

作者： SONG ChuanZhong ZHANG GuoWei WANG YongSheng li jiahao CHEN ZeChao CAI ZhiChuan School of Resources and Environment Hefei University of TechnologyHefei 230009China Department of Geology Northwest UniversityXi’an 710069China

The Luonan-Luanchuan tectonic belt lies between the North China Block and Qinling Mountains, in- cluding the Luonan-Luanchuan fault zone and the strong deformation zone to the north of the fault. The ductile shear zone, imbricate brittle fault and duplex structure in the fault zone now are the expression of the same tectonic event in different depth. Such lineation structure exists in the tectonic belts as mineral lineation, elongation lineation, crenulation lineation, sheath folds and so on, indicating NE-directed plate motion. Fold axes and thrusts in the strong deformation zone are inclined to the Luonan-Luanchuan fault zone at small angles. The structures with different natures show a regular pattern, produced during oblique convergence of plates. The convergence factors are as follows:The direction of plate convergence is 22°, 31° and the angle between the plate convergence direction and plate boundary is 73°, 82° respectively in the west and east segment. The Luonan-Luanchuan tectonic belt was deformed strongly in 372 Ma, resulted from Erlangping back-arc ocean basin subduction sin- istrally and obliquely to North China Block during the collision of North China Block and South China Block.

关键词： Qinling orogenic belt oblique convergence convergence factor strain partitioning continental accretion