检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第6期13卷 24-29页

作者： Wen-Jin Yuan Yi-Juan Zheng Bing-Rong Zhang Yi-Jie lin You li Yan-Yan Qiu xue-ping Yu Department of Infection Disease Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian provinceFujian Medical University Affiliated First Quanzhou HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/*** SUMMARY This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary *** revealed an ileocecal *** discontinuing hydroxyurea therapy for 6 months,follow-up colonoscopy showed a significant reduction in the *** We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

关键词： Hydroxyurea Ulcer Abdominal pain Thrombocythemia Colonoscopy Case report

Optimizing Photovoltaic Performance by Kinetic Quenching of Layered Heterojunctions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2022年第1期40卷 29-37页

作者： li-Feng xu Zhan-Wen xu Jia-ping lin li-Quan Wang Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

The mixing morphology control plays a crucial role in photovoltaic power generation,yet this specific effect on device performances remains ***,we employed computational approaches to delineate the photovoltaic properties of layered heterojunction polymer solar cells with tunable mixing ***-step quench and two-step quench strategies were proposed to adjust the mixing morphology by thermodynamic and kinetic *** computation for the one-step quench revealed that modulating interfacial widths and interfacial roughness could significantly promote the photovoltaic performance of layered heterojunction polymer solar *** two-step quench can provide a buffer at a lower temperature before the kinetic quenching,leading to the formation of small-length-scale islands connected to the interface and a further increase in photovoltaic *** discoveries are supported by recent experimental evidence and are anticipated to guide the design of photovoltaic materials with optimal performance.

关键词： Dissipative particle dynamics Drift-diffusion model Polymer solar cells Quench

Superior Ductile and High-barrier Poly(lactic acid)Films by Constructing Oriented Nanocrystals as Efficient Reinforcement of Chain Entanglement Network and Promising Barrier Wall

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2022年第10期40卷 1201-1212,I0009页

作者： lin Zhou ping-ping xu Shi-Hao Ni ling xu Hao lin Gan-Ji Zhong Hua-Dong Huang Zhong-Ming li Collge of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065China

It is a daunting task to develop a promising strategy at an industrial scale for simultaneously ameliorating ductility and gas barrier performance of poly(lactic acid)(PLA)films in the application of green *** this work,biaxial stretching and constrained annealing were employed to prepare transparent PLA films with superior ductility and barrier *** oriented nano-sized crystals induced by biaxial stretching were developed into regularαform during constrained annealing,which could not only serve as“nano-barrier wall”to impede the diffusion and dissolution of gas molecules,but also strengthen amorphous chain entanglement network as physical crosslink to enhance *** a result,the as-prepared PLA films exhibited an outstanding comprehensive performance with a low oxygen and water vapor permeability coefficient of 0.733×10^(-14) cm^(3)·cm·cm^(-2)·s^(-1)·Pa^(-1) and 3.82×10^(-14) g·cm·cm^(-2)·s^(-1)·Pa^(-1),respectively,outstanding ductility with elongation at break of 66.0%,high yield strength of 84.2 MPa,and good transparency of more than 80%at 550 *** new insight in the relationship between microscopic amorphous and crystalline structure and macroscopic performance is conducive to alleviating the intrinsic defects of brittle and insufficient barrier PLA films without the aid of any heterogenous modifiers,facilitating their widespread commercialization in the booming sustainable packaging market.

关键词： Poly(lactic acid)films Biaxial stretching Constrained annealing Gas barrier properties Ductility

Influence of plasma peening on oxidation of H13 hot work steel in water vapor

在线全文

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2004年第Z1期14卷 305-309页

作者： MIN Yong-an xu Xiao WU Xiao-chun li lin xu Luo-ping School of Materials Science and Engineering Shanghai University Shanghai 200072 China School of Materials Science and Engineering Shanghai University Shanghai 200072 China School of Materials Science and Engineering Shanghai University Shanghai 200072 China School of Materials Science and Engineering Shanghai University Shanghai 200072 China School of Materials Science and Engineering Shanghai University Shanghai 200072 China

The surface oxidation films on H13 steel samples, obtained by different oxidation processes were observed by optical microscope. It is shown that the oxidation speed of H13 steel is increased remarkably due to the surface modification of plasma peening. Further researches were made by XRD, SEM and EDS. The activation of H13 surface caused by plasma peening and the subsequent higher oxygen diffusion rate into the steel seem to be the main reasons of higher oxidation speed. The nitride layer, generally formed on the steel surface under plasma nitriding process, can be substituted by oxide in subsequent oxidation process, which can reduce the risk of heat cracking in some hot work applications. Therefore, the plasma nitriding plus oxidation process is a proper choice for some hot work dies, which demands high hardness to avoid indentation as well as high toughness to avoid cracks.

关键词： oxidation hot work tool steel plasma nitriding surface treatment

Asymptotic solutions for the asymmetric flow in a channel with porous retractable walls under a transverse magnetic field

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2018年第8期39卷 1147-1164页

作者： Hongxia GUO ping lin lin li Beijing Key Laboratory for Magneto-Photoelectrical Composite and Interface Science School of Mathematics and Physics University of Science and Technology Beijing Division of Mathematics University of Dundee School of Mathematics and Physics University of South China

The self-similarity solutions of the Navier-Stokes equations are constructed for an incompressible laminar flow through a uniformly porous channel with retractable walls under a transverse magnetic field. The flow is driven by the expanding or contracting walls with different permeability. The velocities of the asymmetric flow at the upper and lower walls are different in not only the magnitude but also the direction. The asymptotic solutions are well constructed with the method of boundary layer correction in two cases with large Reynolds numbers, i.e., both walls of the channel are with suction, and one of the walls is with injection while the other one is with suction. For small Reynolds number cases, the double perturbation method is used to construct the asymptotic solution. All the asymptotic results are finally verified by numerical results.

关键词： laminar flow asymmetric flow asymptotic solution porous and retractable channel magnetic field

Response Characteristics and Adiabatic Heating during High Strain Rate for TRIP Steel and DP Steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2015年第1期22卷 48-54页

作者： Yi GAO Chao xu Zhong-ping HE Yan-lin HE lin li School of Materials Science and Engineering Shanghai University

By using a static and high-speed material testing machine, tensile deformation behaviors of two kinds of Si- Mn TRIP （transformation induced plasticity） steels and DP （dual phase） steel were studied in a large range of strain rates （0.001-2000 s 1）. Temperature variation during adiabatic heating and the amount of retained austenite at fracture were measured by an infrared thermometer and an Xray stress analyser, respectively. The microstructure of steels was observed by optical microscopy （OM） and scanning electron microscopy （SEM） before and after tensile test. It was found from the experimental results that the tensile strength of these steels increased, and the fracture elonga- tion firstly decreased and subsequently increased, as the strain rate increased in the range ＂of 0.1 - 2000 s -1. The temperature raised during adiabatic heating of TRIP steel was in the range of 100- 300℃, while that of the DP steel was in the range of 100-220℃ . The temperature rise of these steels increased with increasing the strain rate, as well as the amount of the transformed retained austenite in TRIP steels. It was confirmed that austenite to martensite transformation is not suppressed by adiabatic heating.

关键词： strain rate TRIP steel adiabatic heating retained austenite

Establishment and application of minigene models for studying pre-mRNA alternative splicing

在线全文

学校读者我要写书评

暂无评论

Science China(life Sciences) 2004年第3期47卷 211-218页

作者： li Jing CHEN Xianhua lin Wanmin li lishu HAN Yu xu ping Laboratory of Genomic Physiology School of Life Sciences Fudan University Shanghai 200433 China

The objective of the present study is to establish a minigene model for studying pre-mRNA alternative splicing. To prepare the minigene DNA constructs, with human or mouse genomic DNA as templates, GluR-B , FGF-2R and Zis 搈inigene?fragments were amplified us-ing PCR and cloned to the eukaryotic expression vectors. The three constructed minigenes and the expression vectors of Tra2b1 and Zis2 were co-transfected in Hela cells. RT-PCR analysis was performed to semi-quantitatively determine the spliced products from the minigenes. The results demonstrated that the constructed minigenes are useful in studying the pre-mRNA al-ternative splicing in cultured cells. With the established Zis minigene, we for the first time found that Zis2 isoform regulates the alternative splicing of Zis minigene.

关键词： minigene GluR-B FGF-2R Zis Tra2β pre-mRNA splicing.

Collaborative assembly-mediated siRNA delivery for relieving inflammation-induced insulin resistance

在线全文

学校读者我要写书评

暂无评论

Nano Research 2020年第11期13卷 2958-2966页

作者： Shiyang Shen li Zhang Mengru li Zhizi Feng Huixia li Xiao xu Shiqi lin ping li Can Zhang Xiaojun xu Ran Mo State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Drug Discovery for Metabolic DiseasesCenter of Advanced Pharmaceuticals and BiomaterialsChina Pharmaceutical UniversityNanjing210009China

Obesity plays a primary causative role in insulin resistance and hyperglycemia that contributes to type 2 *** lipid storage in the liver renders activation of the resident macrophages and chronic secretion of inflammatory mediators,therefore causing or aggravating insulin ***,we develop collaborative assemblies using a“one-pot”synthesis method for macrophage-specific delivery of small interfering RNAs(siRNAs)that target the inflammatory *** nanocomplex(NC)composed of the siRNA molecule,a synthetic thiol-bearing methacrylated hyaluronic acid(sm-HA)and protamine forms through an electrostatic-driven physical assembly,which is chemically crosslinked to acquire the collaboratively assembled nanocapsule(cNC)*** obtained cNC displays significantly higher stability than *** moieties as flexible assembly units can be easily equipped on cNC for long circulation,active targeting,or controlled siRNA ***-F decorated with folic acid,a macrophage-targeting ligand promotes the siRNA accumulation in the activated macrophages in the liver of the obese mouse ***-F loaded with siRNA targeting inflammatory indicators efficiently control the macrophage inflammatory response by reducing the expression of the inflammatory proteins(>40%reduction)and ameliorating the insulin resistance symptoms of the obese mice.

关键词： small interfering RNA(siRNA)delivery collaborative assembly nanomedicine insulin resistance diabetes

Synthesis,Crystal Structure and Anti-ischemic Activity of(E)-1-(4-(Bis(4-methoxyphenyl)methyl)piperazin-1-yl)-3-(4-acetoxy-3-methoxyphenyl)prop-2-en-1-one

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2015年第5期34卷 681-687页

作者： ZHONG Yan liU Ya-lin xu Zhao-Ying xu Yi li ping WU Bin School of Chemistry and Chemical Engineering Southeast University School of Pharmacy Nanjing Medical University School of Basic Medical Sciences Nanjing Medical University

A new cinnamide derivative,（E）-1-（4-（bis（4-methoxyphenyl）methyl）piperazin-1-yl）-3-（4-acetoxy-3-methoxyphenyl）prop-2-en-1-one（C31H34N2O6,Mr = 530.60）,has been synthesized by the condensation of 1-（bis（4-methoxyphenyl）methyl）piperazine and（E）-3-（4-acetoxy-3-methoxyphenyl）acrylic *** compound was characterized by 1H NMR,13 C NMR,H RMS and single-crystal X-ray *** crystal belongs to the orthorhombic system,space group P212121 with a = 24.946（5）,b = 7.6380（15）,c = 14.555（3） A,V = 2773.3（10） A^3,Z = 4,Dc = 1.271 g/cm^3,F（000） = 1128,μ = 0.088 mm-1,Mo Kα radiation（λ = 0.71073 A）,the final R = 0.0641 and w R = 0.1170.A total of 3009 unique reflections were collected,of which 1760 with I 〉 2σ（I） were *** C（17）–H（17B）···O（3） and C（22）–H（22A）···O（3） interactions as well as intermolecular C（27）–H（27A）···O（3） hydrogen bonds help to stabilize the crystal *** title compound was evaluated for the anti-ischemic activity in vitro and in *** bioassay results indicated that the title compound displayed efficient activities against glutamine-induced neurotoxicity in PC12 cells and significantly prolonged the survival time of mice subjected to acute cerebral ischemia.

关键词： cinnamide crystal structure synthesis anti-ischemic activity