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Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng hai-Hui Jiang Hui-li Kang Yi Jiang Hua-Wei Zhang Xiao-Mei Song Yu-Ze li Wen-li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian Gu Haoyu li Mengyao li Yude Wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat MoS2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@MoS2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,MoS2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@MoS2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Internal electric field Cationic accelerator Ion diffusion kinetics Cathode modification strategy Aqueous zinc ion battery

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氮素穗肥对辽粳212产量的影响

黑龙江农业科学 2020年第5期 21-23页

作者：张满利陈盈王彦荣李全英李如海辽宁省水稻研究所辽宁沈阳110101

辽宁地区水稻生产传统施用氮肥为225 kg·hm-2,以基肥和分蘖肥为主,很少施用穗肥,而适当的前氮后移可以增加水稻的产量。以辽粳212为试验材料,设置不同穗肥施用比例和施用时期,分析不同氮肥模式下辽粳212的产量因素构成。结果表明:在倒... 详细信息

辽宁地区水稻生产传统施用氮肥为225 kg·hm-2,以基肥和分蘖肥为主,很少施用穗肥,而适当的前氮后移可以增加水稻的产量。以辽粳212为试验材料,设置不同穗肥施用比例和施用时期,分析不同氮肥模式下辽粳212的产量因素构成。结果表明:在倒二叶施用,穗肥用量占总肥料的10%,即22.5 kg·hm-2时,产量较为稳定。

关键词：穗肥辽粳212 产量

Preparation of silver nanoparticles through the reduction of straw-extracted lignin and its antibacterial hydrogel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 504-514页

作者： Lou Zhang Shuo li Fu Tang Jingkai Zhang Yuetong Kang Hean Zhang lidong li State Key Laboratory for Advanced Metals and Materials School of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083China

Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial ***,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are usually toxic and may cause water *** this work,Ag NPs(31.2 nm in diameter)were prepared using the extract of straw,an agricultural waste,as the reducing and stabilizing *** analysis revealed that the straw extract contained lignin,the structure of which possesses phenolic hydroxyl and methoxy groups that facilitate the reduction of silver salts into Ag *** surfaces of Ag NPs were negatively charged due to the encapsulation of a thin layer of lignin molecules that prevented their *** the prepared Ag NPs were added to the precursor solution of acrylamide,free radical polymerization was triggered without the need for extra heating or light irradiation,resulting in the rapid formation of an Ag NP-polyacrylamide composite *** inhibition zone test proved that the composite hydrogel possessed excellent antibacterial ability due to the presence of Ag *** prepared hydrogel may have potential applications in the fabrication of biomedical materials,such as antibacterial dressings.

关键词： silver nanoparticles hydrogel straw extraction antibacterial

Study of high-speed-impact-induced conoidal fracture of Ti alloy layer in composite armor plate composed of Ti-and Al-alloy layers

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Defence Technology（防务技术） 2021年第4期17卷 1434-1443页

作者： Peng-ru li Qun-bo Fan Xin-jie Zhu hai-chao Gong School of Materials Science and Engineering Beijing Institute of TechnologyBeijing100081China National Key Laboratory of Science and Technology on Materials Under Shock and Impact Beijing100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing401135China

In order to understand the mechanism of conoidal fracture damage caused by a high-speed fragmentsimulating projectile in titanium alloy layer of a composite armor plate composed of titanium-and aluminum-alloy layers,the ballistic interaction process was successfully simulated based on the Tuler eButcher and GISSMO coupling failure *** simulated conoidal fracture morphology was in good agreement with the three-dimensional industrial-computed-tomography ***,three main damage zones(zones I,II,and III)were identified besides the crater area,which are located respectively near the crater area,at the back of the target plate,and directly below the crater *** the high-speed-impact conditions,in zone II,cracks began to form at the end of the period of crack formation in zone I,but crack formation in zone III started before the end of crack formation in zone ***,the damage mechanism differed for different stress *** microcracks in zone I were formed both by void connection and shear *** the formation of zone I,the stress triaxiality ranged from2.0 to1.0,and the shear failure mechanism played a dominant *** microcracks in zone II showed the combined features of shear deformation and void connection,and during the formation process,the stress triaxiality was between 0 and 0.5 with a mixed failure ***,the microcracks in zone III showed obvious characteristics of void connection caused by local *** the zone III formation,the triaxiality was 1.0e1.9,and the ductile fracture mechanism was dominant,which also reflects the phenomenon of spallation.

关键词： Titanium alloy targets Conoidal fracture Stress triaxiality Microscopic mechanism

Effect of sintering temperature on the electrolysis of TiO_2

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International Journal of Minerals,Metallurgy and Materials 2012年第7期19卷 636-641页

作者： Ze-quan li li-yue ru Cheng-guang Bai Na Zhang hai-hua Wang College of Chemistry and Chemical Engineering Chongqing University Chongqing 400044 China College of Materials Science and Engineering Chongqing University Chongqing 400044 China

The effects of sintering temperature on the microstructure and the conductivity of TiO2 cathodes were studied by examining the phase composition, microstructure, and element contents of the sintered cathodes and the cathodic products using X-ray diffraction and scan- ning electronic microscopy-energy dispersive spectrometry. The oxygen vacancy, conductivity, average pore diameter, and specific surface area of the sintered cathodes were detected by X-ray photoelectron spectroscopy, four-point probe, and ASPA 2010. The results showed that TiO2 phase transformations occurred, and oxygen vacancies formed with the increase of sintering temperature. The cathodic conductivity improved, but the average pore diameter and the effective response area of the TiO2 cathode were reduced when the sintering temperature in- creased. These phenomena could weaken the contact between reaction ions and electrons and also had the same effect on the cathodes and the molten salt. Moreover, they were disadvantageous to ion migration, so a lower sintering temperature was favorable for the microstructure of electrolysis. Consequently, the cathodic conductivity may be improved, but the microstrucatre became compact with the increase of sin- tering temperature. The cathodic products at different temperatures indicated that the cathodic conductivity was more important for electroly- sis.

关键词： titanium dioxidegelectrolysis sintering microstructure

Research on tasks schedule and data transmission of video sensor networks based on intelligent agents and intelligent algorithms

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The Journal of China Universities of Posts and Telecommunications 2009年第6期16卷 84-91,112页

作者： HUANG hai-ping WANG ru-chuan SUN li-juan WANG hai-yuan XIAO Fu College of Computer Nanjing University of Posts and Telecommunications Nanjing 210003 China State Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 China

As a novel application technology,wireless video sensor networks become the current research focus,especially on target tracking and surveillance *** on multiple agents＇ technique,this article introduces a series of intelligent algorithms such as simulated annealing algorithm（SA）,genetic algorithm（GA）,and ant colony optimization algorithm（ACO） or their mixed algorithms,to resolve the optimization of tasks schedule and data *** article analyzes the performance of abovementioned algorithms and verifies their feasibility associated with *** simulations demonstrates that the mixed algorithms based on SA and GA obtain the optimal solution to tasks schedule,and those combined with SA-ACO show advantages on multimedia sensor networks routing optimization.

关键词： video sensor networks intelligent algorithm tasks schedule optimal routing agent

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

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World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： Bo-Fan Chen li liu Fang-Zhen lin hai-Min Zeng hai-Qiang Huang Chun-Fang Zhang Cong-Cong liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-lin Wang Bin Chen De-Le liu Yun liu Zheng-Zheng li Xin-Xing Zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina Department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

Gut-brain axis as a bridge in obesity and depression:Mechanistic exploration and therapeutic prospects

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World Journal of Psychiatry 2025年第1期15卷 12-20页

作者： rui-Ying Fang Xiao-rui Pan Xin-Xing Zeng Zheng-Zheng li Bo-Fan Chen hai-Min Zeng Jie Peng The Second Clinical Medical College The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

A recent study by Wang et al,published in the World Journal of Psychiatry,provided preventative and therapeutic strategies for the comorbidity of obesity and *** gut-brain axis,which acts as a two-way communication system between the gastrointestinal tract and the central nervous system,plays a pivotal role in the pathogenesis of these *** suggests that metabolic byproducts,such as short-chain fatty acids,lipopolysaccharide and bile acids,which are generated by the gut microbiota,along with neurotransmitters and inflammatory mediators within the gut-brain axis,modulate the host's metabolic processes,neuronal regulation,and immune responses through diverse *** interaction between obesity and depression via the gut-brain axis involves disruptions in the gut microbiota balance,inflammatory immune responses,and alterations in the neuroendocrine *** the gut-brain axis,for example,through a ketogenic diet,the use of probiotics,and the supplementation of antioxidants,offers new remedial approaches for obesity and *** research that explores the mechanisms of the gut-brain axis is needed to provide more evidence for clinical treatment.

关键词： Gut-brain axis Obesity Depression Gut microbiota Mechanism