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Ecological Economy 2024年第1期20卷 2-24页

作者： SHI Xiong-tian WU Feng-qing CHEN Yang dai li-li School of Business Administration and Tourism Management Yunnan UniversityKunming 650500CHINA School of Economics and Management Yanshan UniversityQinhaungdao 066000CHINA Business School University of SouthamptonSouthampton SO152UAUK

Based on the supply-side perspective,the improved STIRPAT model is applied to reveal the mechanisms of supply-side factors such as human,capital,technology,industrial synergy,institutions and economic growth on carbon emissions in the Yangtze River Delta(YRD)through path analysis,and to forecast carbon emissions in the YRD from the baseline scenario,factor regulation scenario and integrated scenario to reach the *** results show that:(1)Jiangsu's high carbon emission pattern is the main reason for the YRD hindering the synergistic regulation of carbon emissions.(2)Human factors,institutional factors and economic growth factors can all contribute to carbon emissions in the YRD region,while technological and industrial factors can generally suppress carbon emissions in the YRD region.(3)Under the capital regulation scenario,the YRD region has the highest level of carbon emission synergy,with Jiangsu reaching its peak five years *** the balanced regulation scenario,the YRD region as a whole,Jiangsu,Zhejiang and Anhui reach the peak as scheduled.

关键词： Yangtze River Delta carbon peaking scenario forecasting STIRPAT model

基于PI3K/Akt信号通路研究灯盏花乙素对子宫内膜癌Ishikawa细胞的影响

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中国临床药理学杂志 2024年第1期40卷 27-31页

作者：代丽丽王景魏许瑞马庆亚王娜都治香河北医科大学第一医院产科河北石家庄050000 河北医科大学第一医院妇科河北石家庄050000

目的研究灯盏花乙素对子宫内膜癌Ishikawa细胞的影响,并分析与磷脂酰肌醇3激酶(PI3K)/蛋白激酶B(Akt)信号通路的相关性。方法将Ishikawa细胞分为空白组及低、中、高剂量实验组,分别用含0、5、10及20μmol·L-1的灯盏花乙素的完全培养基... 详细信息

目的研究灯盏花乙素对子宫内膜癌Ishikawa细胞的影响,并分析与磷脂酰肌醇3激酶(PI3K)/蛋白激酶B(Akt)信号通路的相关性。方法将Ishikawa细胞分为空白组及低、中、高剂量实验组,分别用含0、5、10及20μmol·L-1的灯盏花乙素的完全培养基处理。用细胞计数试剂盒-8(CCK-8)实验检测细胞活力;用平板克隆实验检克隆形成能力;用划痕及Transwell实验检测转移及侵袭能力;用流式细胞术检测凋亡;用蛋白质印迹法检测蛋白表达情况。结果空白组和低、中、高剂量实验组48 h的细胞活力分别为(100.00±0.00)%、(78.51±7.54)%、(52.93±4.91)%和(41.62±5.33)%;克隆形成率分别为(100.00±0.00)%、(56.59±6.34)%、(35.23±4.62)%和(10.66±1.91)%;划痕愈合率分别为(53.70±6.19)%、(40.59±4.75)%、(34.25±4.40)%和(15.78±2.14)%;侵袭细胞数分别为(189.70±14.06)、(106.82±12.67)、(84.37±8.13)和(53.74±6.78)个;基质金属蛋白酶-2(MMP-2)蛋白相对表达水平分别为0.96±0.10、0.73±0.06、0.68±0.08和0.42±0.05;MMP抑制药-1(TIMP-1)蛋白相对表达水平分别为0.35±0.04、0.51±0.05、0.74±0.08和1.20±0.14;细胞凋亡率分别为(4.21±0.53)%、(15.83±2.42)%、(22.72±3.85)%和(34.41±4.67)%;B淋巴细胞瘤-2(Bcl-2)蛋白表达水平分别为1.38±0.15、0.90±0.10、0.56±0.06和0.24±0.03;Bcl-2相关X蛋白(Bax)表达水平分别为0.31±0.02、0.44±0.04、0.93±0.11和1.26±0.14;PI3Kp85蛋白表达水平分别为0.67±0.05、0.42±0.04、0.36±0.02和0.28±0.03;磷酸化Akt(p-Akt)蛋白表达水平分别为0.78±0.06、0.53±0.04、0.46±0.05和0.42±0.03;低、中、高剂量实验组上述指标与空白组比较,差异均有统计学意义(P<0.05或P<0.01)。结论灯盏花乙素可以通过调控PI3K/Akt信号通路抑制Ishikawa细胞增殖、转移及侵袭,并诱导其凋亡。

关键词：灯盏花乙素子宫内膜癌转移侵袭凋亡

Process intensification for the synthesis and purification of battery-grade li_(2)CO_(3)with microfluidics

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Particuology 2024年第7期90卷 106-117页

作者： Haodu li Jie Zhang lin dai Le Du Jiqin Zhu The State Key Laboratory of Chemical Resource Engineering College of Chemical EngineeringBeijing University of Chemical TechnologyBeijing 100029China

Battery-grade lithium carbonate(li_(2)CO_(3))with a purity of higher than 99.5 wt%is of great importance as a high value-added lithium ***,influences of different reaction systems and process control on product purity remain ***,a membrane dispersion microreactor was used to enhance the mass transfer of preparation and purification processes in homogeneous and heterogeneous *** systems of Na_(2)CO_(3)–liCl,NH_(4)HCO_(3)–liCl,and NH_(3)·H_(2)O−CO_(2)−liCl,CO_(2)purification based on carbonation and decomposition were *** li_(2)CO_(3)purity was increased by the improvement of mixing *** carbonation time was reduced by 62.5%and 58.3%for the NH_(3)·H_(2)O−CO_(2)and CO_(2)purification systems,*** the two ammonia-based systems,li_(2)CO_(3)particles with a purity of 99.7–99.8 wt%were one-step prepared with a size of 3–5μm,which also met the requirement of the battery-grade *** purity was further increased to 99.9 wt%by CO_(2)purification and liHCO_(3)*** investigation could provide a feasible alternative for the controllable preparation of battery-grade li_(2)CO_(3)in one or multiple steps.

关键词： Microfluidics Battery grade li_(2)CO_(3) Process intensification High purity

Flocculation process of fine-grained sediments by the combined effect of salinity and humus in the Changjiang Estuary

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Acta Oceanologica Sinica 2007年第1期26卷 140-149页

作者： liU Qizhen li Jiufa dai Zhijun li Daoji State Key Laboratory of Estuarine and Coastal Research East China Normal University Shanghai 200062 China

For the great amount of organic compounds and the variation of salinity in the Changjiang Estuary, the study on the flocculation process of fine-grained sediments by the combined effect of salinity and humus in the high-turbid system is of critical significance for the understanding of the mechanism of the formation of the turbidity maximum （TM） . For the great amount of organic compounds and the variation of salinity in the Changjiang Estuary, the study on the flocculation process of fine-grained sediments by the combined effect of salinity and humus in the high-turbid system is of critical significance for the understanding of the mechanism of the formation of the turbidity maximum （TM） . The effects of salinity and humus on the fine-grained sediments have been analyzed through the synthetic study of the aspects of flocculation/coagulation power （ F）, diameter （D） and zeta potential （Z）. And the microcosmic configuration of the flocs has been analyzed by using a scan electron microscope and Fourier Transform Infrared Spectrometry. The results show that：（ 1 ） with the increase of salinity, F and D become greater and Z becomes smaller, and with the increase of the concentration of humus, F becomes smaller, but D and Z become greater; （2） the microcosmic configuration of the flocculation shows that humus packs on the fine sediments in the form of salt, and the flocculation model of C - P - OM （C stands for clay; P cations; OM organic materials） can successfully demonstrate the mechanism of the formation of the finegrained sediments in the high-turbid area of the Changjiang Estuary.

关键词： Changjiang Estuary fine-grained sediment floceulation salinity

Catalytic anode surface enabling in situ polymerization of gel polymer electrolyte for stable li metal batteries

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Nano Research 2024年第6期17卷 5216-5223页

作者： Guocheng li Kang liang Yuanjian li Xiangrui Duan lin Fu Zhao Cai Zhaofu Zhang Jiangnan dai Yongming Sun Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China The Institute of Technological Sciences Wuhan UniversityWuhan 430074China Faculty of Materials Science and Chemistry China University of Geoscience(Wuhan)Wuhan 430074China

Employing quasi-solid-state gel polymer electrolyte(GPE)instead of the liquid counterpart has been regarded as a promising strategy for improving the electrochemical performance of li metal ***,the poor and uneven interfacial contact between li metal anode and GPE could cause large interfacial resistance and electrochemical li stripping/plating inhomogeneity,deteriorating the electrochemical ***,we proposed that the functional component of composite anode could work as the catalyst to promote the in situ polymerization reaction,and we experimentally realized the integration of polymerized-dioxolane electrolyte and li/li_(22)Sn_(5)/liF composite electrode with low interfacial resistance and good stability by in situ catalyzation ***,the reaction kinetics and stability of metallic li anode were significantly *** a demonstration,symmetric cell using such a GPE-li/li_(22)Sn_(5)/liF integration achieved stable cycling beyond 250 cycles with small potential hysteresis of 25 mV at 1 mA·cm^(−2)and 1 mAh·cm^(−2),far outperforming the counterpart regular GPE on pure *** with liNi0.5Co0.3Mn0.2O2,the full cell with the GPE-li/li_(22)Sn_(5)/liF integration maintained 85.7%of the original capacity after 100 cycles at 0.5 C(1 C=200 mA·g^(−1)).Our research provides a promising strategy for reducing the resistance between GPE and li metal anode,and realizes li metal batteries with enhance electrochemical performance.

关键词： catalyzation polymerization interface resistance interfacial stability li metal batteries electrochemical performance

Balance energy-efficient and real-time with reliable communication protocol for wireless sensor network

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The Journal of China Universities of Posts and Telecommunications 2013年第1期20卷 37-46页

作者： liU Zhi-xin dai li-li MA Kai GUAN Xin-ping Institute of Electrical Engineering Yanshan University School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University

In many wireless sensor network applications, it should be considered that how to trade off the inherent conflict between energy efficient communication and desired quality of service such as real-time and reliability of transportation. In this paper, a novel routing protocols named balance energy-efficient and real-time with reliable communication （BERR） for wireless sensor networks （WSNs） are proposed, which considers the joint performances of real-time, energy efficiency and reliability. In BERR, a node, which is preparing to transmit data packets to sink node, estimates the energy cost, hop count value to sink node and reliability using local information gained from neighbor nodes. BERR considers not only each sender＇ energy level but also that of its neighbor nodes, so that the better energy conditions a node has, the more probability it will be to be chosen as the next relay node. To enhance real-time delivery, it will choose the node with smaller hop count value to sink node as the possible relay candidate. To improve reliability, it adopts retransmission mechanism. Simulation results show that BERR has better performances in term of energy consumption, network lifetime, reliability and small transmitting delay.

关键词： wireless sensor network tradeoff energy efficiency real-time reliable communication retransmission lifetime of network

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黄连膏抗过敏作用机制初步研究

新疆中医药 2024年第2期42卷 1-3页

作者：戴丽莉卢军赵翡翠赵生俊新疆医科大学附属中医医院新疆乌鲁木齐830000 新疆维吾尔自治区中药炮制重点实验室新疆乌鲁木齐830000

目的探究黄连膏的抗过敏作用。方法取KM小鼠随机分为空白组、模型组、阳性组、基质组、黄连膏低、中、高剂量组,采用2,4-二硝基氯苯(2,4-dinitrochlorobenzene,DNCB)致小鼠过敏性皮炎模型,研究黄连膏抗过敏作用。结果黄连膏可显著抑制D... 详细信息

目的探究黄连膏的抗过敏作用。方法取KM小鼠随机分为空白组、模型组、阳性组、基质组、黄连膏低、中、高剂量组,采用2,4-二硝基氯苯(2,4-dinitrochlorobenzene,DNCB)致小鼠过敏性皮炎模型,研究黄连膏抗过敏作用。结果黄连膏可显著抑制DNCB诱发湿疹小鼠的耳肿胀度,明显改善湿疹小鼠耳组织病理皮损,显著降低耳组织表皮厚度,减少真皮层肥大细胞数目,并且可显著抑制小鼠血清中总IgE水平和血清特异IgE水平。结论黄连膏具有明显的抗过敏作用,其抗过敏作用主要与减轻炎性损伤、抑制免疫反应及降低总IgE水平和血清特异IgE水平有关。

关键词：黄连膏小鼠过敏性皮炎模型抗过敏耳肿胀度

Ultrahigh strength and uniform corrosion in Zn-li alloys through ultrahigh pressure supersaturated solid solution treatment for biodegradable orthopedic applications

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Rare Metals 2024年第10期43卷 5284-5304页

作者： Wan-Ying li Yi-Long dai Wen-Hao Cai Si-Han lin lin Guo De-Chuang Zhang Yuncang li Cuie Wen School of Materials Science and Engineering Xiangtan University Department of Prosthodontics Shanghai Ninth People′s HospitalShanghai Jiao Tong University Key Laboratory of Low Dimensional Materials&Application Technology Ministry of EducationXiangtan University School of Engineering RMIT UniversityMelbourne

Zn-li alloys are considered promising candidate materials for biodegradable orthopedic implant applications due to their high mechanical performance and good ***,the presence of a large number of second-phase particles in this class of Zn alloys can lead to severe localized degradation due to micro-galvanic corrosion,which is detrimental to the mechanical integrity of the alloys during tissue healing in the human *** this study we report ultrahigh strength,uniform corrosion,good cytocompatibility,and effective antibacterial ability in Zn-x li（x=0.3,0.5,0.7;wt%） alloys achieved through supersaturated solid solution treatment （SSST） at 375℃ under ultrahigh pressure of 3 GPa.A high concentration of β-liZn4phases coexisted with the-Zn matrix in the as-cast Zn-x li alloys,whereas almost all the li dissolved into the-Zn matrix of SSST *** yield strength was 437 MPa for SSST Zn-0.3li,592 MPa for SSST Zn-0.5 li and 686 MPa for SSST *** SSST Zn-li alloys showed uniform degradation with remarkably reduced degradation rates compared to their as-cast *** 25% concentration extracts of the Zn-x li alloys demonstrated no cytotoxicity toward MC3T3-E1 cells,and the alloys exhibited effective antibacterial ability agains methicillin-resistant staphylococcus aureus.

关键词： Corrosion behavior Mechanical property Supersaturated solid solution treatment (SSST) Ultrahigh pressure Zn-li alloy

Prenatal cadmium exposure impairs neural tube closure via inducing excessive apoptosis in neuroepithelium

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Journal of Environmental Sciences 2024年第4期138卷 572-584页

作者： Shiyong Zhu Xuenan li Xueyan dai Jinlong li College of Veterinary Medicine Northeast Agricultural UniversityHarbin 150030China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment Northeast Agricultural UniversityHarbin 150030China Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine Northeast Agricultural UniversityHarbin 150030China

Birth defects have become a public health *** hazardous environmental factors exposure to embryos could increase the risk of birth ***,a toxic environmental factor,can cross the placental barrier during *** woman may be subjected to cadmium before taking precautionary protective ***,the link between birth defects and cadmium remains *** exposure can induce excessive apoptosis in neuroepithelium during embryonic development *** exposure activated the p53 via enhancing the adenosine 5‘-monophosphate(AMP)-activated protein kinase(AMPK)and reactive oxygen species'(ROS)*** cadmium decreases the level of Paired box 3(Pax3)and murine double minute 2(Mdm2),disrupting the process of p53 *** p53 accumulation induced excessive apoptosis in neuroepithelium during embryonic development *** apoptosis led to the failure of neural tube *** study emphasizes that environmental materials may increase the health risk for *** caused the failure of neural tube closure during early embryotic *** women may be exposed by cadmium before taking precautionary protective actions,because of cadmium concentration-containing foods and environmental tobacco *** suggests that prenatal cadmium exposure is a threatening risk factor for birth defects.

关键词： Cadmium Neural tube closure Excessive apoptosis p53 Embryogenesis

Effect of streamlined nose length on aerodynamic performance of high-speed train with a speed of 400 km/h

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第7期25卷 525-540页

作者： Nianxun li Tian li Zhiyuan dai Deng QIN Jiye ZHANG State Key Laboratory of Rail Transit Vehicle System Southwest Jiaotong UniversityChengdu 610031China

The streamlined nose length(SNL)plays a crucial role in determining the aerodynamic performance of high-speed *** appropriate SNL can not only effectively reduce the magnitude of aerodynamic drag and lift forces,but also improve the performance of the high-speed train in tunnel passing and crosswind *** this study,a numerical simulation of the aerodynamic performance of high-speed trains at a speed of 400 km/h,with varying SNLs,is conducted using the k-ωshear stress transport(SST)turbulence *** different SNLs include 6.0,7.0,8.0,9.0,9.8,12.0,15.0,and 18.0 *** order to validate the accuracy of the numerical simulation,its results are compared with wind tunnel test data obtained from the *** simulation is carried out using compressible and incompressible gases to determine the effect of gas compressibility on *** impact of SNL on the aerodynamic performance of the trains is analyzed in terms of aerodynamic forces,velocity,and pressure *** comparison to the original train,the train with a 6.0 m SNL experienced a 10.8%increase in overall aerodynamic ***,the lift forces on the head and tail cars increased by 35.7%and 75.5%,*** the other hand,the train with an 18.0 m SNL exhibited a 16.5%decrease in aerodynamic ***,the lift forces on the head and tail cars decreased by 21.9%and 49.7%,*** aerodynamic drag force of the entire train varies linearly with the SNL,while the aerodynamic lift of the tail car follows a quadratic function in relation to the SNL.

关键词： Streamlined nose length(SNL) High-speed train Aerodynamic performance Numerical simulation Flow structures