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水电能源科学 1999年第3期17卷 68-69页

作者：康小海汪秉文李国宽华中理工大学

研究运用等微增率方法解决母管制运行机组的负荷经济分配和安全运行问题，即在外部电网负荷变动时，在锅炉、汽轮发电机组之间进行负荷的调度与分配，以符合安全性、经济性的指标要求．

关键词：母管制运行机组负荷经济分配电厂汽轮发电机

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基于轻量化荷载试验评估桥梁剩余承载能力

城市道桥与防洪 2025年第2期 167-170页

作者：杨丙文黎雅乐南京交通职业技术学院路桥与港航工程学院江苏南京211188 江苏开放大学建筑工程学院江苏南京210036

对桥梁的承载能力检测,目前认为桥梁荷载试验是最直接的方法,但在桥梁荷载试验检测过程中,需要较长时间的交通封闭作业,对车辆与行人的通行会造成一定的影响,且需要的配重较多,会给试验带来较为繁重的外业工作量,而且桥梁荷载试验方法... 详细信息

对桥梁的承载能力检测,目前认为桥梁荷载试验是最直接的方法,但在桥梁荷载试验检测过程中,需要较长时间的交通封闭作业,对车辆与行人的通行会造成一定的影响,且需要的配重较多,会给试验带来较为繁重的外业工作量,而且桥梁荷载试验方法对评估桥梁剩余承载能力是没有理论依据的。通过单辆重车缓慢行驶在桥面,采集相应的截面的参数响应的研究方法,结合有限元模型计算,计算其在单辆重车作用下的加载效率系数和在设计荷载作用下的理论参数值,推算在设计荷载作用下桥梁实际产生的效应参数值,来判定桥梁的设计合理性及施工质量的可靠性,并根据现行设计规范要求,计算其若达到设计规范限值时,需加载的荷载值,该值可作为推算出桥梁剩余承载能力值。

关键词：桥梁承载能力参数响应

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陶瓷超硬磨具工作层体积密度的测量

金刚石与磨料磨具工程 2019年第3期39卷 88-92页

作者：邢波李丙文陈学伟张林州陈学彬赵延军闫宁郑州磨料磨具磨削研究所有限公司郑州450001 超硬材料磨具国家重点实验室郑州450001 国家磨料磨具质量监督检验中心郑州450001

依据JB/T 7999—2013《固结磨具体积密度、总气孔率和吸水率试验方法》标准检测陶瓷超硬磨具工作层体积密度,并对其影响因素进行分析。结果表明:检测时取样量应大于0.50g,样品质量减少,体积密度呈下降趋势;当样品体积密度值超过2.85g/c... 详细信息

依据JB/T 7999—2013《固结磨具体积密度、总气孔率和吸水率试验方法》标准检测陶瓷超硬磨具工作层体积密度,并对其影响因素进行分析。结果表明:检测时取样量应大于0.50g,样品质量减少,体积密度呈下降趋势;当样品体积密度值超过2.85g/cm^3时,可省去抽真空处理操作步骤;当体积密度值在2.50~2.85g/cm^3时,可将抽真空处理操作改为在去离子水中浸泡1h;当体积密度值小于2.50g/cm^3时,需经抽真空处理。

关键词：陶瓷超硬磨具工作层体积密度抽真空处理

人粒细胞集落刺激因子受体膜外区在昆虫细胞中的表达

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生物工程学报 1999年第4期15卷 466-469页

作者：赵炳文李蕾李福胜陈爱君曾革非张智清侯云德中国预防医科院病毒基因工程国家重点实验室北京100052

以胎盘组织提取的ｍＲＮＡ为模板，ＲＴ ＰＣＲ扩增人粒细胞集落刺激因子（Ｇ ＣＳＦ）受体膜外区ＣＲＨ的ｃＤＮＡ片段，克隆于供体质粒ｐＦＡＳＴＢＡＣ１，与杆状病毒表达载体Ｂａｃｍｉｄ同源... 详细信息

以胎盘组织提取的ｍＲＮＡ为模板，ＲＴ ＰＣＲ扩增人粒细胞集落刺激因子（Ｇ ＣＳＦ）受体膜外区ＣＲＨ的ｃＤＮＡ片段，克隆于供体质粒ｐＦＡＳＴＢＡＣ１，与杆状病毒表达载体Ｂａｃｍｉｄ同源重组后，转染昆虫细胞ＳＦ９，获得重组杆状病毒并证明了ＣＲＨ的高效表达。表达产物经Ｇ ＣＳＦ亲和层析进一步纯化，纯度可达９０％以上。受体竞争性结合实验结果表明，该表达产物能特异性结合Ｇ ＣＳＦ，具有较高的亲和力（Ｋｄ＝３．８ｎｍｏｌ／Ｌ）。

关键词：粒细胞集落刺激因子受体杆状病毒表达系统

Relationship between spatial heterogeneity and wavelength in multisensor airborne images

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Geo-Spatial Information Science 2015年第1期18卷 56-64页

作者： bingwen QIU Wen QI Chongcheng CHEN Weijiao li Key Laboratory of Spatial Data Mining&Information Sharing of Ministry of Education Spatial Information Research Centre of Fujian ProvinceFuzhou UniversityFuzhou 350002China

Variogram has been utilized to exploring the spatial heterogeneity of remote sensing images,especially its association with spatial ***,very few attentions have been drawn on evaluating the spatial heterogeneity of multisensor airborne imagery and its relationship with spectral ***,an investigation was carried out on multisensor airborne images to determine the relation between spatial heterogeneity and spectral wavelength for woodland,grass,and urban landscapes by applying variogram *** airborne thematic mapper(ATM),compact airborne spectrographic imager(CASI),and Specim AISA Eagle airborne images at Harwood Forest,Monks wood,Cambridge,and River Frome areas,UK,were *** revealed that(1)the red band contained greater spatial variability than near-infrared wavelengths and other visible wavebands;(2)there was a steep gradient at the red edge in reference to its spatial variability of multisensor airborne images;(3)only for natural landscape such as woodland and grass,near-infrared waveband contains greater within-scene variations than the blue and green bands;(4)compared with the discrepancy of spatial resolution introduced by multisensor images(ATM,CASI,and Eagle),the specific landscape and spectral bands were more important in determining heterogeneity by means of original visible,near-infrared bands,and normalized difference vegetation index(NDVI).These findings remained us to be caution when combining and interpreting spatial variability and spatial structures derived from airborne images with different spatial resolution and spectral ***,the outcomes of this study also have considerable implications in terms of designing and choosing suitable images for different applications.

关键词： variogram modeling spatial heterogeneity airborne thematic mapper(ATM)imagery compact airborne spectrographic imager(CASI)imagery Eagle airborne imagery landscape wavelength

Recognition and Localization of Maize Leaf and Stalk Trajectories in RGB Images Based on Point-line Net

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Plant Phenomics 2024年第3期6卷 669-683页

作者： bingwen liu Jianye Chang Dengfeng Hou Yuchen Pan Dengao li Jue Ruan College of Computer Science and Technology(College of Data Science) Taiyuan University of TechnologyTaiyuan 030024ShanxiChina Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural Sciences518120 ShenzhenChina

Plant phenotype detection plays a crucial role in understanding and studying plant biology,agriculture,and *** involves the quantification and analysis of various physical traits and characteristics of plants,such as plant height,leaf shape,angle,number,and growth *** accurately detecting and measuring these phenotypic traits,researchers can gain insights into plant growth,development,stress tolerance,and the influence of environmental factors,which has important implications for crop *** these phenotypic characteristics,the number of leaves and growth trajectory of the plant are most ***,obtaining these phenotypes is labor intensive and financially *** the rapid development of computer vision technology and artificial intelligence,using maize field images to fully analyze plant-related information can greatly eliminate repetitive labor and enhance the efficiency of plant ***,it is still difficult to apply deep learning methods in field environments to determine the number and growth trajectory of leaves and stalks due to the complex backgrounds and serious occlusion problems of crops in field *** preliminarily explore the application of deep learning technology to the acquisition of the number of leaves and stalks and the tracking of growth trajectories in field agriculture,in this study,we developed a deep learning method called Point-line Net,which is based on the Mask R-CNN framework,to automatically recognize maize field RGB images and determine the number and growth trajectory of leaves and *** experimental results demonstrate that the object detection accuracy(mAP50)of our Point-line Net can reach 81.5%.Moreover,to describe the position and growth of leaves and stalks,we introduced a new lightweight"key point"detection branch that achieved a magnitude of 33.5 using our custom distance verification ***,these findings provide valuable insights for future field pl

关键词： localization leaf based images maize point-line recognition stalk trajectories

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网状阳极系统技术标准讨论

石油化工腐蚀与防护 2005年第6期22卷 57-59页

作者：邱政权冯洪臣李丙文韦锦平冯骅河北黄骅市瑞晨防腐材料有限公司河北黄骅061100 青海油田管道输油处青海格尔木816000 中国石油天然气管道局河北廊坊065000

提供了网状阳极材料选用参数、设计依据、安装步骤以及调试、验收要求。制定的阳极网接地电阻计算公式,为电源设备选型提供了依据。指出了设计阳极网及电缆选用应遵循的原则,为广大设计人员提供了参考标准。

关键词：网状阳极阳极片导电片电缆接头参比电极

Isolation and characterization of AHL-degrading bacteria from fish and pond sediment

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Journal of Oceanology and limnology 2019年第4期37卷 1460-1467页

作者： li Miaoyu XI bingwen QIN Ting CHEN Kai XIE Jun Wuxi Fisheries College Nanjing Agricultural University Wuxi 214081 China Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization Ministry of Agriculture Freshwater Fisheries Research Center Chinese Academy of Fishery Sciences Wuxi 214081 China

Quorum sensing (QS) disruption is considered as a potential alternative strategy to combat bacterial diseases in aquaculture. In this study, we isolated and identified bacteria degrading QS molecules from pond sediment and fish intestine. A total of 132 strains were obtained in the enrichment culture, of which two strains were identified as Enterobacter sp. f003 and Staphylococcus sp. sw120, being isolated from the fish intestine and pond sediment, respectively. We found that strains f003 and sw120 could degrade acyl-homoserine lactones (AHLs) and cause no hemolysis of sheep red blood cells. The AHL lactonase (aiiA) homologous gene in the two strains was detected in PCR amplification and the high-degrading activity to N-hexanoyl-L-homoserine lactone (C6-HSL) and AHLs secreted from pathogenic Aeromonas hydrophila was assessed. Meanwhile, the artificial infection of cyprinid Carassius auratus gibelio with intraperitoneal injection showed that the two strains were avirulent. Therefore, the obtained indigenous bacteria are candidate probiotics against pathogenic A. hydrophila in aquaculture.

关键词： quorum sensing (QS) Aeromonas hydrophila probiotic Enterobacter Staphylococcus

Spatiotemporal analysis of vegetation variability and its relationship with climate change in China

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Geo-Spatial Information Science 2014年第3期17卷 170-180页

作者： bingwen QIU Weijiao li Ming ZHONG Zhenghong TANG Chongcheng CHEN National Engineering Research Centre of Geospatial Information Technology Key Laboratory of Spatial Data Mining and Information Sharing of Ministry of EducationFuzhou UniversityFuzhou 350002FujianChina Community and Regional Planning Program University of Nebraska-LincolnLincolnNEUSA

This paper investigated spatiotemporal dynamic pattern of vegetation,climate factor,and their complex relationships from seasonal to inter-annual scale in China during the period 1982–1998 through wavelet transform method based on GIMMS ***,most vegetation canopies demonstrated obvious seasonality,increasing with latitudinal ***,obvious dynamic trends were observed in both vegetation and climate change,especially the positive *** 70%areas were observed with obvious vegetation greening up,with vegetation degradation principally in the Pearl River Delta,Yangtze River Delta,and *** warming trend was observed across the whole country(>98%area),stronger in Northern *** over half of area(58.2%)obtained increasing rainfall trend,around a quarter of area(24.5%),especially the Central China and most northern portion of China,exhibited significantly negative rainfall ***,significantly positive normalized difference vegetation index(NDVI)–climate relationship was generally observed on the de-noised time series in most vegetated regions,corresponding to their synchronous stronger seasonal ***,at inter-annual level,the NDVI–climate relationship differed with climatic regions and their long-term trends:in humid regions,positive coefficients were observed except in regions with vegetation degradation;in arid,semiarid,and semihumid regions,positive relationships would be examined on the condition that increasing rainfall could compensate the increasing water requirement along with increasing *** study provided valuable insights into the long-term vegetation–climate relationship in China with consideration of their spatiotemporal variability and overall trend in the global change process.

关键词： vegetation variability wavelet transform climate change non-stationary normalized difference vegetation index(NDVI)

Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2006-2025页

作者： bingwen Ding Zhu Zhu Cong Guo Jiaxin li Yong Gan Miaorong Yu State Key Laboratory of Drug Research and Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Pharmacy Henan UniversityKaifeng 475004China NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients National Institutes for Food and Drug ControlBeijing 100050China

Diabetes,characterized by hyperglycemia,is a major cause of death and disability ***,such as insulin and glucagon-like peptide-1(GLP-1)analogs,have shown promise as treatments for diabetes due to their ability to mimic or enhance insulin's actions in the *** to subcutaneous injection,oral administration of anti-diabetic peptides is a preferred ***,biological barriers significantly reduce the efficacy of oral peptide *** advancements in drug delivery systems and formulation techniques have greatly improved the oral delivery of peptide therapeutics and their efficacy in treating *** review will highlight(1)the benefits of oral anti-diabetic peptide therapeutics;(2)the biological barriers for oral peptide delivery,including pH and enzyme degradation,intestinal mucosa barrier,and biodistribution barrier;(3)the delivery platforms to overcome these biological ***,the review will discuss the prospects in this *** information provided in this review will serve as a valuable guide for future developments in oral anti-diabetic peptide therapeutics.

关键词： Oral peptides Diabetes Delivery platforms Insulin Glucagon-like peptide-1 Biodistribution Biological barriers Targeted delivery