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Influence of heat treatment on microstructure of a newβ-solidifyingγ-TiAl alloy

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Journal of Iron and Steel Research International 2025年第1期32卷 239-248页

作者： li Quan Xiao-bing li Peng Xue Jun-jie Hao Kun Qian Bo Chen Jian-zhong li Kui liu School of Metallurgy Northeastern UniversityShenyang110819LiaoningChina Department of Materials Science and Technology Ji Hua LaboratoryFoshan528200GuangdongChina

The high strength and stability of the full-lamellar structure guarantee the industrial application of theβ-solidifyingγ-TiAl ***,it is a huge challenge to design an alloy with good hot-deformability as well as the full-lamellar *** low-cost Ti-42.5Al-2Mn-0.4Mo-0.1B-0.1C(at.%)alloy was designed,which undergoes bothβandαsingle-phase region during the *** is found that the full-lamellar structure can be obtained by the solution heat treatment at 1230℃ for 20 min and then aging treatment at 800℃ for 3 ***,a new microstructure,namely,the pearlitic-like microstructure(PM)induced by theα_(2)/γ→βo+γcellular reaction was observed when the aging temperature is increased to above 800℃.The volume fraction of the PM is gradually increased from 0%to 25.5%,65%,and 94%according to elevated aging temperature from 800 to 900,1000,and 1050℃,*** mechanism of the reducedα_(2)/γlamellae and PM formation was discussed regarding the heterogeneous distribution ofβstabilizing elements and the interface energy stored inα_(2)/γlamellae.

关键词： β-γ-TiAl Alloy design Two-step heat treatment Full-lamellar structure Cellular reaction

Systematic review of amyloid-beta clearance proteins from the brain to the periphery:implications for Alzheimer's disease diagnosis and therapeutic targets

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Neural Regeneration Research 2025年第12期20卷 3574-3590页

作者： Letian Huang Mingyue liu Ze li bing li Jiahe Wang Ke Zhang Department of Oncology Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Developmental Cell Biology Key Laboratory of Cell BiologyMinistry of Public HealthChina Medical UniversityShenyangLiaoning ProvinceChina Department of Family Medicine Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Amyloid-beta clearance plays a key role in the pathogenesis of Alzheimer's disease.H oweve r,the variation in functional proteins involved in amyloid-beta clearance and their correlation with amyloid-beta levels remain unclea *** this study,we conducted meta-analyses and a systematic review using studies from the PubMed,Embase,Web of Science,and Cochrane library databases,including journal articles published from inception to J une 30,*** inclusion criteria included studies comparing the levels of functional proteins associated with amyloid-beta clearance in the blood,cere b rospinal fluid,and brain of healthy controls,patients with mild cognitive impairment,and patients with Alzheimer's ***,we analyzed the correlation between these functional proteins and amyloid-beta levels in patients with Alzheimer's *** methodological quality of the studies was assessed via the Newcastle-Ottawa *** to heterogeneity,we utilized either a fixed-effect or random-effect model to assess the 95%confidence interval(CI)of the standard mean difference(SMD)among healthy controls,patients with mild cognitive impairment,and patients with Alzheimer's *** findings revealed significant alterations in the levels of insulin-degrading enzymes,neprilysin,matrix metalloproteinase-9,cathepsin D,receptor for advanced glycation end products,and P-glycoprotein in the brains of patients with Alzheimer's disease,patients with mild cognitive impairment,and healthy *** cerebrospinal fluid,the levels of triggering receptor expressed on myeloid cells 2 and ubiquitin C-terminal hydrolase L1 are altered,whereas the levels of TREM2,CD40,CD40L,CD14,CD22,cathepsin D,cystatin C,andα2 M in peripheral blood ***,TREM2 and cathepsin D showed changes in both brain(SMD=0.31,95%CI:0.16-0.47,P<0.001,I^(2)=78.4%;SMD=1.24,95%CI:0.01-2.48,P=0.048,I^(2)=90.1%)and peripheral blood(SMD=1.01,95%CI:0.35-1.66,P=0.003,I^(2)=96.5%;SMD=7.55,95%CI:3.92-11.18,P<0.001,I^(

关键词： Alzheimer’s disease amyloid-β blood‒brain barrier cerebrospinal fluid diagnostic biomarker meta-analysis mild cognitive impairment peripheral blood systematic review therapeutic targets

Atractylenolide Ⅰ ameliorates post-infectious irritable bowel syndrome by inhibiting the polymerase Ⅰ and transcript release factor and c-Jun N-terminal kinase/inducible nitric oxide synthase pathway

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Journal of Traditional Chinese Medicine 2025年第1期45卷 57-65页

作者： YUAN Jianan CHENG Kunming li Chao ZHANG Xiang DING Zeyu li bing ZHENG Yongqiu Provincial Engineering Laboratory for Screening and Re-evaluation of Active Compounds of Herbal Medicines in Southern Anhui Teaching and Research Section of Traditional Chinese MedicineSchool of PharmacyWannan Medical College Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences

OBJECTIVE: To explore the therapeutic effect and target of atractylenolide I(AT-I) on post-infectious irritable bowel syndrome(PI-IBS) rats. METHODS: Therefore, the preliminarily mechanism of AT-I in anti-PI-IBS were first predicted by network pharmacology and molecular docking, then the possible signaling pathways were systematically analyzed. Finally, the potential therapeutic targets and possible signaling pathways of AT-I on PI-IBS in Sprague-Dawley(SD) rat model were verified by experiments. RESULTS: AT-I could alleviate PI-IBS symptoms and reduce the expression of tumor necrosis factor α, interleukin-6 and Interferon-gamma in PI-IBS SD rat model and inhibit the c-Jun N-terminal kinase/inducible nitric oxide synthase(JNK/iNOS) pathway. Notably, AT-I treatment could inhibit the overexpression of polymerase Ⅰ and transcript release factor(PTRF). CONCLUSION: AT-I could alleviate PI-IBS symptoms through downregulation of PTRF and inhibiting the JNK/iNOS pathway. This study not only provides a scientific basis to clarify the anti-PI-IBS effect of AT-I and its mechanism but also suggests a novel promising therapeutic strategy to treat the PI-IBS.

关键词： MAP kinase signaling system atractylenolide Ⅰ network pharmacology nitric oxide synthase type Ⅱ polymerase Ⅰ and transcript release factor post-infectious irritable bowel syndrome

Attar: RRAM-based in-memory attention accelerator with software-hardware co-optimization

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Science China(Information Sciences) 2025年第03期68卷 371-387页

作者： bing li Ying QI Ying WANG Yinhe HAN Information Engineering College Capital Normal University Research Center for Intelligent Computing Systems Institute of Computing TechnologyChinese Academy of Sciences

The attention mechanism has become a pivotal component in artificial intelligence, significantly enhancing the performance of deep learning applications. However, its quadratic computational complexity and intricate computations lead to substantial inefficiencies when processing long sequences. To address these challenges, we introduce Attar, a resistive random access memory(RRAM)-based in-memory accelerator designed to optimize attention mechanisms through software-hardware co-optimization. Attar leverages efficient Top-k pruning and quantization strategies to exploit the sparsity and redundancy of attention matrices, and incorporates an RRAM-based in-memory softmax engine by harnessing the versatility of the RRAM crossbar. Comprehensive evaluations demonstrate that Attar achieves a performance improvement of up to 4.88× and energy saving of 55.38% over previous computing-in-memory(CIM)-based accelerators across various models and datasets while maintaining comparable accuracy. This work underscores the potential of in-memory computing to enhance the efficiency of attention-based models without compromising their effectiveness.

关键词： RRAM computing-in-memory attention pruning quantization

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A revised classification of Dryopteridaceae based on plastome phylogenomics and morphological evidence,with the description of a new genus,Pseudarachniodes

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Plant Diversity 2025年第1期47卷 34-52页

作者： Zheng-Yu Zuo Germinal Rouhan Shi-Yong Dong Hong-Mei liu Xin-Yu Du li-bing Zhang Jin-Mei Lu Germplasm Bank of Wild Species and Yunnan Key Laboratory of Crop Wild Relatives OmicsKunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Institut de Systematique EvolutionBiodiversite(ISYEB)Museum National d’Histoire NaturelleCNRSSorbonne UniversiteEcole Pratique des Hautes EtudesUniversite des AntillesCP3957 rue Cuvier 75005ParisFrance Key Laboratory of Plant Resources Conservation and Sustainable Utilization South China Botanical GardenChinese Academy of SciencesGuangzhou 510650GuangdongChina Center for Integrative Conservation&Yunnan Key Laboratory for Conservation of Tropical Rainforests and Asian Elephants Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglun 666303YunnanChina Missouri Botanical Garden 4344 Shaw BlvdSt Louis 63110MOUSA Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041SichuanChina State Key Laboratory of Plant Diversity and Specialty Crops Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina

Dryopteridaceae are the largest fern family and include nearly 20%of extant fern diversity,with 24 currently recognized *** and delineation of genera within this family have varied *** three-subfamily classification of Dryopteridaceae was based primarily on molecular phylogenetic relationships but lacked morphological evidence,and the phylogenetic relationships of the subfamilies and genera of Dryopteridaceae are only partially resolved.A comprehensive and robust phylogeny is urgently *** heterogeneous morphology of the current members of Dryopteridaceae makes the family and its subfamilies difficult to define by single morphological characteristics or even character *** carried out phylogenetic analyses to reconstruct a highly supported phylogeny of *** analyses recovered 24 strongly supported clades grouped into seven major clades of *** morphological characters including habit,rhizome shape,frond morphology,rachis-costae architecture,appendages on stipe base and lamina,and soral arrangement were found to be informative for identifying different major clades and clades in *** on phylogenetic reconstruction and morphological analysis,we presented an updated infra-familial classification of Dryopteridaceae with seven subfamilies and 24 genera including four newly proposed subfamilies(Ctenitidoideae,Lastreopsidoideae,Pleocnemioideae,and Polystichopsidoideae).Morphological character combinations of each subfamily are summarized,and a key is *** genera sensu PPG I are recognized,with Stigmatopetris reclassified into Dryopteridoideae and Arthrobotrya considered a synonym of Teratophyllum.A new genus Pseudarachniodes is *** revised classification will serve as a foundational framework for future investigations on taxonomy,biogeography,and diversification of the most species-rich Dryopteridaceae in ferns.

关键词： Ctenitidoideae Infra-familial Morphological diagnostic characters Phylogenomics Rachis-costae architecture Stigmatopetris

Mediating role of health literacy in the relationship between social isolation and psychological distress among pre-frail older adults

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World Journal of Psychiatry 2025年第1期15卷 137-144页

作者： Juan Fang li-Hui li Ming-Qian He Yue Ji Dong-Yan Lu li-bing Zhang Jin-Lan Yao School of Medicine Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina

BACKGROUND Frailty has become a significant public health *** recent increase in the number of frail older adults has led to increased attention being paid to psycho-logical care services in *** social isolation of pre-frail older adults can impact their psychological *** To explore the mediating effect of health literacy between social isolation and psychological distress among communitydwelling older adults with *** This descriptive cross-sectional study was conducted with 254 pre-frail older individuals aged 60 years and *** isolation,health literacy,and psycholo-gical distress were comprehensively measured using the Lubben Social Network Scale-6,12-item Short-Form Health literacy Questionnaire,and the Kessler Psy-chological Distress *** were evaluated using the SPSS 27.0 package program and the PROCESS macro *** statistical analyses,correlation analyses,and bootstrap mediation tests were used to assess associations between the *** The results showed that social isolation had an effect on health literacy among pre-frail older adults(β=0.240,Pliteracy was identified effect on psychological distress among pre-frail older persons(β=-0.307,Pliteracy partially mediated the relationship between social isolation and psychological distress among community-dwelling older adults with pre-frailty,with a mediation effect of-0.074,accounting for 17.83%of the total effect.

关键词： Frail Ageing Psychological distress Health literacy Social isolation

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中国式现代化道路的辩证特性与世界历史意义

领导科学 2025年第1期 25-32页

作者：王凤李兵西南大学马克思主义学院四川大学马克思主义学院

马克思世界历史理论揭示了作为客观事实的世界历史是物质生产发展和普遍交往扩大共同作用的结果,其走向共产主义“自由王国”的道路既具统一性又具多样性,其发展的价值指归在于实现人的自由全面发展。以马克思世界历史理论辩证把握中国... 详细信息

马克思世界历史理论揭示了作为客观事实的世界历史是物质生产发展和普遍交往扩大共同作用的结果,其走向共产主义“自由王国”的道路既具统一性又具多样性,其发展的价值指归在于实现人的自由全面发展。以马克思世界历史理论辩证把握中国式现代化道路,可以看出,其既遵循世界历史演进的普遍规律又独具自身特殊性,既坚持中国共产党的领导又保障人民当家作主,既立足于现代化建设的阶段性又注重目标的长期性,既彰显鲜明的中华民族特色又着眼于世界现代化发展格局,是普遍性和特殊性、党性和人民性、阶段性和长期性、民族性和世界性的辩证统一。立足这一视角,中国式现代化道路以破解资本逻辑的支配重构了世界现代化图景,以延展人的现代化属性优化了全球现代化实践主体,以中国道路拓展了发展中国家寻求现代化的途径,从图景重构、主体优化、道路拓展等方面为创造人类文明新形态贡献了独树一帜的中国力量。

关键词：马克思世界历史理论中国式现代化道路人类文明新形态

NaOH(碱)诱导Co/MoO_(3)重构催化氨硼烷水解释氢

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燃料化学学报(中英文) 2025年第1期53卷 174-182页

作者：张文珂刘军辉李冰李梦婷李想许爱荣河南科技大学化学化工学院河南洛阳471023 河南科技大学材料科学与工程学院河南洛阳471023

本研究以MoO_(3)为载体通过液相还原法制备了Co/MoO_(3)催化剂,用于催化氨硼烷水解释氢反应。Co/MoO_(3)催化剂在无NaOH(碱)加入的体系中没有催化活性,不能催化氨硼烷水解释放氢气,而在有NaOH(碱)加入的体系中表现出优异的催化释氢性能... 详细信息

本研究以MoO_(3)为载体通过液相还原法制备了Co/MoO_(3)催化剂,用于催化氨硼烷水解释氢反应。Co/MoO_(3)催化剂在无NaOH(碱)加入的体系中没有催化活性,不能催化氨硼烷水解释放氢气,而在有NaOH(碱)加入的体系中表现出优异的催化释氢性能。对Co/MoO_(3)催化剂的组成结构在反应前后变化的表征分析表明,Co/MoO_(3)催化剂中的组分是Co和Mo的无定形态存在的物质,非晶态的结构导致了在氨硼烷水解释氢反应中没有催化活性。在NaOH(碱)诱导作用下,Co/MoO_(3)催化剂的组成结构由无定形态转变为片状Co(OH)_(2)分散在片状堆叠的MoO_(3)上的结构。NaOH(碱)的诱导重构作用使Co/MoO_(3)催化剂在氨硼烷水解释氢反应中由没有催化活性转变为可以在15 min内使氨硼烷完全脱氢。

关键词：氨硼烷水解释氢非贵金属催化剂构效关系

基于改进SuperPoint与线性转换器的可见光红外匹配算法

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北京航空航天大学学报 2025年第1期51卷 340-348页

作者：伍薇鲜勇苏娟张大巧李少朋李冰火箭军工程大学作战保障学院西安710025 火箭军工程大学核工程学院西安710025 清华大学自动化系北京100084

针对可见光和红外图像的异源图像匹配难度大、误匹配率高的问题,提出一种基于改进SuperPoint与线性转换器的深度学习匹配算法。首先在SuperPoint网络结构的基础上,引入特征金字塔的思想构建特征描述分支,基于铰链损失函数进行训练,从而... 详细信息

针对可见光和红外图像的异源图像匹配难度大、误匹配率高的问题,提出一种基于改进SuperPoint与线性转换器的深度学习匹配算法。首先在SuperPoint网络结构的基础上,引入特征金字塔的思想构建特征描述分支,基于铰链损失函数进行训练,从而较好地学习可见光与红外图像多尺度深层次特征,增大图像同名点对描述子的相似度;在特征匹配模块,利用线性转换器对SuperGlue匹配算法进行改进,聚合特征以提高匹配性能。在多个数据集上对所提算法进行实验验证,结果表明,与现有的算法相比,所提算法获得了更好的匹配效果,提高了匹配准确率。

关键词：红外图像可见光图像异源图像匹配特征金字塔线性转换器