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bipolar membrane electrodialysis integrated with in-situ CO_(2)absorption for simulated seawater concentrate utilization,carbon storage and production of sodium carbonate

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Journal of Environmental Sciences 2024年第8期142卷 21-32页

作者： Jingtao bi Tianyi Chen Yue xie Ruochen Shen bin li Mengmeng Sun Xiaofu Guo Yingying Zhao School of Chemical Engineering and Technology Hebei University of TechnologyTianjin 300401China Engineering Research Center of Seawater Utilization Technology of Ministry of Education School of Chemical Engineering and TechnologyHebei University of TechnologyTianjin 300401China Hebei Collaborative Innovation Center of Modern Marine Chemical Technology Tianjin 300401China Tianjin Key Laboratory of Chemical Process Safety Tianjin 300130China Shandong Technology Innovation Center of Seawater and Brine Efficient Utilization Weifang 262737China

In the context of carbon capture,utilization,and storage,the high-value utilization of carbon storage presents a significant *** address this challenge,this study employed the bipolar membrane electrodialysis integrated with carbon utilization technology to prepare Na_(2)CO_(3)products using simulated seawater concentrate,achieving simultaneous saline wastewater utilization,carbon storage and high-value production of Na_(2)CO_(3).The effects of various factors,including concentration of simulated seawater concentrate,current density,CO_(2)aeration rate,and circulating flow rate of alkali chamber,on the quality of Na_(2)CO_(3)product,carbon sequestration rate,and energy consumption were *** the optimal condition,the CO_(3)^(2-)concentration in the alkaline chamber reached a maximum of 0.817 mol/L with 98 mol%*** resulting carbon fixation rate was 70.50%,with energy consumption for carbon sequestration and product production of 5.7 k Whr/m^(3)CO_(2)and1237.8 k Whr/ton Na_(2)CO_(3),*** coupling design provides a triple-win outcome promoting waste reduction and efficient utilization of resources.

关键词： bipolar membrane electrodialysis(BMED) Carbon capture Utilization and storage(CCUS) Seawater concentrate Sodium carbonate

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Effects of Co and Nb on the Crack of Additive Manufacturing Nickel-Based Superalloys

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Acta Metallurgica Sinica(English Letters) 2024年第9期37卷 1601-1610页

作者： Kejie Tan Jinli xie Hailong Qin bin Xu Guichen Hou Jinguo li Zhongnan bi Ji Zhang Beijing Key Laboratory of Advanced High Temperature Materials Central Iron&Steel Research InstituteBeijing100081China Beijing GAONA Materials&Technology Co. LTDBeijing100081China Superalloys Division Institute of Metal ResearchChinese Academy of SciencesShenyang110016China

Increasing the print quality is the critical requirement for the additive manufactured complex part of aero-engines of nickel-based superalloys.A study of the effects of Co and Nb on the crack is performed focusing on the selective laser melting(SLM)nickel-based *** this paper,the solvus temperature of γ',crack characteristics,microstructure,thermal expansion,and mechanical properties of SLM nickel-based superalloy are investigated by varying the content of Co and *** alloy with 15Co/0Nb shows the highest comprehensive *** increases the crack risk and thermal deformation,and then Co accelerates the stress ***,Co is an extremely important alloying element for improving the quality of SLM nickel-based ***,the crack growth kinetics and the strain difference are discussed to reveal the SLM crack regular that is affected by time or *** analysis work on the effect of alloying elements can obtain an effective foundational theory to guide the composition optimization of SLM nickel-based superalloys.

关键词： Nickel-based superalloys Selective laser melting Element effect Crack

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Study on Molecular Chain Morphology of Konjac Glucomannan

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Agricultural Sciences in China 2003年第7期2卷 798-803页

作者： li bin and xie bi-jun(Natural Product Chemistry Research Laboratory , Food Science Department, Huazhong Agricultural University , Wuhan 430070, P. R. China) Natural Product Chemistry Research Laboratory Food Science Department Huazhong Agricultural University Wuhan 430070 P. R. China

The long-range structure of konjac glucomannan(KGM)is studied by using laser light scatter(LLS), gel permeation chromatography(GPC)and method of viscosidity. The weight-average molecular weight(Mw), root-mean-square ratio of gyration[(S2)1/2], second viral coefficient(A2)and multi-dispersion coefficient(Mw/Mn)are 1.04×106, 105. 0±0. 9 nm,(-1. 59±0.28)×10-3 mol ml g-2 and 1.015±0.003, respectively. Mark-Houwink equation is established as [η] = 5. 96×10-2Mw0.73 and the molecular chain parameters are as follows: ML=982. 82 nm-1, Lp = 27. 93 nm, d = 0. 74 nm, h = 0. 26 nm, L = l 054.11 nm. Further more molecular chain morphology of KGM is studied by using atom force microscope(AFM)and transmission electronic microscope(TEM), and the result shows that the KGM molecular is an extending semi-flexible linear chain without branch. Therefore, the image of molecular chain morphology confirms the deduction drawn by Mark-Houwink equation and molecular chain parameters.

关键词： Konjac glucomannan Molecular chain parameter Molecular morphology Laser light scatter Atom force microscope

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Recyclable Technology of Thermosetting Resins for High Thermal Conductivity Materials Based on Physical Crushing

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Energy & Environmental Materials 2024年第6期7卷 378-387页

作者： An Zhong Congzhen xie bin Gou Jiangang Zhou Huasong Xu Song Yu Daoming Zhang Chunhui bi Hangchuan Cai licheng li Rui Wang School of Electric Power South China University of TechnologyGuangzhou 510641China

Epoxy resin,characterized by prominent mechanical and electric-insulation properties,is the preferred material for packaging power electronic ***,the efficient recycling and reuse of epoxy materials with thermally cross-linked molecular structures has become a daunting ***,we propose an economical and operable recycling strategy to regenerate waste epoxy resin into a high-performance *** particle size of waste epoxy micro-spheres(100–600μm)with core-shell structure is obtained through simple mechanical crushing and boron nitride surface *** using smattering epoxy monomer as an adhesive,an eco-friendly composite material with a“brick-wall structure”can be *** continuous boron nitride pathway with efficient thermal conductivity endows eco-friendly composite materials with a preeminent thermal conductivity of 3.71 W m^(−1)K^(−1)at a low content of 8.5 vol%h-BN,superior to pure epoxy resin(0.21 W m^(−1)K^(−1)).The composite,after secondary recycling and reuse,still maintains a thermal conductivity of 2.12 W m^(−1)K^(−1)and has mechanical and insulation properties comparable to the new epoxy resin(energy storage modulus of 2326.3 MPa and breakdown strength of 40.18 kV mm^(−1)).This strategy expands the sustainable application prospects of thermosetting polymers,offering extremely high economic and environmental value.

关键词： brick-wall structure epoxy thermosetting physical recycling thermal management

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The role of corneal endothelium in macular corneal dystrophy development and recurrence

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Science China(life Sciences) 2024年第2期67卷 332-344页

作者： bi-Ning Zhang Benxiang Qi Chunxiao Dong bin Zhang jun Cheng Xin Wang Suxia li Xiaoyun Zhuang Shijiu Chen Haoyun Duan Dewei li Sujie Zhu Guoyun li Yihai Cao Qingjun Zhou lixin xie Eye Institute of Shandong First Medical University Qingdao Eye Hospital of Shandong First Medical UniversityQingdao 266071China State Key Laboratory Cultivation Base Shandong Provincial Key Laboratory of OphthalmologyQingdao 266071China School of Ophthalmology Shandong First Medical UniversityQingdao 250021China Department of Medicine Qingdao UniversityQingdao 266071China Eye Institute of Shandong First Medical University Eye Hospital of Shandong First Medical University(Shandong Eye Hospital)Jinan 250021China Department of Ophthalmology School of Clinical MedicineWeifang Medical UniversityWeifang 261072China Institute of Translational Medicine College of MedicineQingdao UniversityQingdao 266071China Key Laboratory of Marine Drugs of Ministry of Education Shandong Provincial Key Laboratory of Glycoscience and GlycotechnologySchool of Medicine and PharmacyOcean University of ChinaQingdao 266071China Laboratory for Marine Drugs and bioproducts Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266071China Department of Microbiology Tumor and Cell BiologyBiomedicumKarolinska InstitutetStockholm 17177Sweden

Macular corneal dystrophy(MCD)is a progressive,bilateral stromal dystrophic disease that arises from mutations in carbohydrate sulfotransferase 6(CHST6).Corneal transplantation is the ultimate therapeutic solution for MCD ***,postoperative recurrence remains a significant *** conducted a retrospective review of a clinical cohort comprising 102 MCD patients with 124 eyes that underwent either penetrating keratoplasty(PKP)or deep anterior lamellar keratoplasty(DALK).Our results revealed that the recurrence rate was nearly three times higher in the DALK group(39.13%,9/23 eyes)compared with the PKP group(10.89%,11/101 eyes),suggesting that surgical replacement of the corneal endothelium for treating MCD is advisable to prevent postoperative *** experimental data confirmed the robust m RNA and protein expression of CHST6 in human corneal endothelium and the rodent homolog CHST5 in mouse *** knockdown of wild-type Chst5 in mouse corneal endothelium(AC^(siChst5)),but not in the corneal stroma,induced experimental MCD with similar extracellular matrix synthesis impairments and corneal thinning as observed in MCD *** carrying Chst5 point mutation also recapitulated clinical phenotypes of MCD,along with corneal endothelial *** injection of wild-type Chst5 rescued the corneal impairments in AC^(siChst5)mice and retarded the disease progression in Chst5 mutant ***,our study provides new mechanistic insights and therapeutic approaches for MCD treatment by highlighting the role of corneal endothelium in MCD development.

关键词： macular corneal dystrophy recurrence corneal endothelium keratan sulfate penetrating keratoplasty

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Genetically predicted fatty liver disease and risk of psychiatric disorders: A mendelian randomization study

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World Journal of Clinical Cases 2024年第14期12卷 2359-2369页

作者： Wei-Ming Xu Hai-Fu Zhang Yong-Hang Feng Shuo-jun li bi-Yun xie Department of Medicine The First People's Hospital of FuyangHangzhou 311400Zhejiang ProvinceChina Department of Internal Medicine The First People's Hospital of FuyangHangzhou 311400Zhejiang ProvinceChina

BACKGROUND Non-alcoholic fatty liver disease(NAFLD)and alcohol-related liver disease(Ar-LD)constitute the primary forms of chronic liver disease,and their incidence is progressively increasing with changes in lifestyle *** studies have do-cumented a correlation between the occurrence and development of prevalent mental disorders and fatty *** To investigate the correlation between fatty liver and mental disorders,thus ne-cessitating the implementation of a mendelian randomization(MR)study to elu-cidate this *** Data on NAFLD and ArLD were retrieved from the genome-wide association studies catalog,while information on mental disorders,including Alzheimer's disease,schizophrenia,anxiety disorder,attention deficit hyperactivity disorder(ADHD),bipolar disorder,major depressive disorder,multiple personality dis-order,obsessive-compulsive disorder(OCD),post-traumatic stress disorder(PTSD),and schizophrenia was acquired from the psychiatric genomics consor-tium.A two-sample MR method was applied to investigate mediators in signifi-cant *** After excluding weak instrumental variables,a causal relationship was identified between fatty liver disease and the occurrence and development of some psychia-tric ***,the findings indicated that ArLD was associated with a significantly elevated risk of developing ADHD(OR:5.81,95%CI:5.59-6.03,Pbipolar disorder(OR:5.73,95%CI:5.42-6.05,P=0.03),OCD(OR:6.42,95%CI:5.60-7.36,Pbipolar disorder(OR:55.08,95%CI:3.59-845.51,Pliver disease and an increased risk of a broad range of psychiatric disorders,namely bipolar disorder,OCD,and PTSD,highlighting the significance of preven-tive measures against psy

关键词： Non-alcoholic fatty liver disease Alcohol-related liver disease Psychiatric disorders Mendelian randomization Single nucleotide polymorphisms

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Chaiqin Chengqi Decoction as an adjuvant treatment for mild/moderately severe hypertriglyceridemic acute pancreatitis: A retrospective study

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World Journal of Clinical Cases 2024年第11期12卷 1918-1928页

作者： Hai-Fu Zhang Ze-Xuan Su Yong-Hang Feng Shuo-jun li bi-Yun xie Department of Internal Medicine The First People's Hospital of FuyangHangzhou 311400Zhejiang ProvinceChina

Hypertriglyceridemia is the third leading cause of acute pancreatitis(AP),and its incidence is *** to its relatively insidious etiology,it is easy to be ignored in the early *** China,Chaiqin Chengqi Decoction(CQCQD)has long been employed for treating *** To evaluate the effectiveness of CQCQD in patients diagnosed with mild/moderately severe hypertriglyceridemic AP(HTG-AP).METHODS In this study,the clinical data of 39 patients with HTG-AP admitted from January 2019 to November 2022 were *** changes of blood lipids,gastrointestinal symptoms,and abdominal pain before and after treatment were analyzed and compared between the two *** Twenty patients were treated with the conventional HTG-AP regimen,and 19 patients were additionally treated with *** receiving treatment,the triglycerides(TG)level of the CQCQD group was lower than that of the CQCQD group(3.14±0.25 mmol/L vs 4.96±0.47 mmol/L,P<0.01).After 3 d of treatment,the patients in the CQCQD group had more bowel movements than the control group(2.51±0.25 times vs 1.00±0.17 times,P=0.01).The gastrointestinal function of most patients returned to normal,and the acute gastrointestinal injury score was significantly lower than that of the control group(0.11±0.07 vs 0.42±0.11,P<0.01).CONCLUSION In patients with HTG-AP,CQCQD can significantly reduce the TG level,shorten the recovery time of defecation,significantly improve the gastrointestinal function.

关键词： Hypertriglyceridemic acute pancreatitis Chinese medicine Chaiqin Chengqi Decoction Serum lipid Triglycerides

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Reducing Operation Emissions and Improving Work Efficiency Using a Pure Electric Wheel Drive Tractor

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Engineering 2024年第6期37卷 230-245页

作者： Chang-Kai Wen Wen Ren Qing-Zhen Zhu Chun-Jiang Zhao Zhen-Hao Luo Sheng-li Zhang bin xie Zhi-jun Meng Research Center of Intelligent Equipment Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China State Key Laboratory of Intelligent Agricultural Power Equipment Beijing 100097China BYD Company limited Shenzhen 518118China College of Agricultural Engineering Jiangsu UniversityZhenjiang 212013China College of Engineering China Agricultural UniversityBeijing 100083China

In response to the problems of excessive greenhouse-gas and particulate emissions and the low traction efficiency of conventional diesel tractors in the field,a purely electric wheel-side drive tractor was studied,including an electric motor drive system,a battery ballast system,and an electro–hydraulic suspension *** paper develops a dynamics model of an electric tractor-ploughing unit under complex soil conditions,leading to the proposal of an active control method for drive wheel torque and a joint control method for the traction force of the suspension system and the front-and rear-axle loads of a ***,the tractor is prototyped and assembled,and ploughing tests are carried *** ploughing results show that the active torque-distribution control method proposed in this study reduces the tractor slip by 14.83%and increases the traction efficiency by 10.28%compared with the average torquedistribution *** with the conventional traction control mode,the joint control method for traction and ballast proposed in this paper results in a 3.7%increase in traction efficiency,a 15.05%decrease in slip,and a 4.9%reduction in total drive motor energy *** study will help to improve the operation quality and traction efficiency of electric tractors in complex soil conditions.

关键词： Electric tractor Ploughing unit Torque distribution Active ballast Traction performance

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Demethylase-assisted site-specific detection of N^(1)-methyladenosine in RNA

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Chinese Chemical Letters 2024年第5期35卷 397-401页

作者： jun Xiong Ke-Ke Chen Neng-bin xie Wei Chen Wen-Xuan Shao Tong-Tong Ji Si-Yu Yu Yu-Qi Feng bi-Feng Yuan College of Chemistry and Molecular Sciences Research Center of Public HealthRenmin Hospital of Wuhan UniversitySchool of Public HealthWuhan UniversityWuhan 430071China Department of Laboratory Medicine Zhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan 430071China

The dynamic RNA modifications have been viewed as new posttranscriptional regulator in modulating gene expression as well as in a broad range of physiological processes.N^(1)-methyladenosine(m^(1)A)is one of the most prevalent modifications existing in multiple types of ***-depth investigation of the functions of m^(1)A requires the site-specific assessment of m^(1)A stoichiometry in ***,we established a demethylase-assisted method(DA-m^(1)A)for the site-specific detection and quantification of m^(1)A in RNA.N^(1)-methyl group in m^(1)A could result in the stalling of reverse transcription at m^(1)A site,thus producing the truncated *** AlkB is a demethylase that can demethylate m^(1)A to produce adenine in RNA,thus generating full-length cDNA from AlkB-treated *** of the produced amounts of full-length cDNA by quantitative real-time PCR can achieve the site-specific detection and quantification of m^(1)A in *** the DA-m^(1)A method,we examined and successfully confirmed the previously well-characterized m^(1)A sites in various types of RNAs with low false positive *** addition,we found that the level of m^(1)A was significantly decreased at the bromodomain containing 2(BRD2)mRNA position 1674 and CST telomere replication complex component 1(CTC1)mRNA position 5643 in human hepatocellular carcinoma *** results suggest that these two m^(1)A sites in mRNA may be involved in liver *** together,the DA-m^(1)A method is simple and enables the rapid,cost-effective,and site-specific detection and quantification of m^(1)A in RNA,which provides a valuable tool to decipher the functions of m^(1)A in human diseases.

关键词： N^(1)-methyladenosine RNA modification AlkB demethylase RNA epigenetics Quantitative real-time PCR Hepatocellular carcinoma

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A bioorthogonal Post-modification of N^(6)-Isopentenyl Adenosine i^(6) A RNA in live Cells

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CCS Chemistry 2024年第9期6卷 2241-2253页

作者： li-jun xie Hou-Ping Cheng Meng-Yuan Chen Xin Wang li liu bi-Feng Yuan liang Cheng Beijing National Laboratory for Molecular Sciences(BNLMS) CAS Key Laboratory of Molecular Recognition and FunctionCAS Research/Education Center for Excellence in Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100190 School of Public Health Wuhan UniversityWuhan 430071 University of Chinese Academy of Sciences Beijing 100049

Selective methods for modulating RNA epigenetic modifications within living cells and organisms represent attractive techniques for investigating biological functions and medicinal *** contrast to enzymatic methods,abiotic chemical modulation offers access to diverse new-to-natural *** herein report a visible light-assisted bioorthogonal reaction involving flavin mononucleotide,sodium azide,and blue light *** concert with previous chemical approaches mimicking the demodification pathway,our system functions as a powerful and selective post-modification enzyme that targets N^(6)-prenyl adenosine i^(6) A in RNA and enables the efficient construction of an artificial N^(6)-cyanomethyl adenosine(cnm^(6) A).Notably,most endogenous biomacromolecular functions,including other common RNA epigenetics,remained ***,we have successfully modified i^(6) A in tRNA to cnm^(6) A in human cells and establish this system as a bona fide bioorthogonal reaction with potential applications in chemical biology and in-cell modulation.

关键词： chemical post-modification bioorthogonal reactions RNA modifications N^(6)-isopentenyl adenosine N^(6)-cyanomethyl adenosine

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